Purdue-led TOMI project receives $3.5M grant to turn a decade of data into new tools and strategies for tomato farmers WEST LAFAYETTE, Ind. — Indiana ranks third in the nation for tomato production. Lori Hoagland, a professor in Purdue University’s Department of Horticulture and Landscape Architecture, recently received ​​a third grant from the U.S. Department of Agriculture’s National Institute of Food and Agriculture (USDA-NIFA) for the Tomato Organic Management and ...

More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime. Does an encounter with one virus influence how your immune system responds to a different one? If so, how? Does it weaken your defenses, boost them, or have some other impact altogether? These are questions Rockefeller University scientists from the Laboratory of Virology and Infectious Disease,headed by Charles M. Rice, and Weill Cornell Medicine’s Laboratory of Epigenetics and Immunity, headed by Steven Z. Josefowicz, teamed up to answer in a new study published in the journal Immunity. ...

Hoboken, N.J., September 30, 2024 – It has been estimated that nearly 300 million people, or about 4% of the global population, are afflicted by some form of depression. But detecting it can be difficult, particularly when those affected don’t (or won't) report negative feelings to friends, family or clinicians. Now Stevens professor Sang Won Bae is working on several AI-powered smartphone applications and systems that could non-invasively warn us, and others, that we may be becoming depressed. “Depression is a major challenge,” says Bae. “We want to help.” "And since most people in the world today use smartphones daily, this could ...

The addition of the cancer immunotherapy drug atezolizumab to the standard of care concurrent chemoradiation (cCRT) did not improve overall survival for patients with limited-stage small cell lung cancer (LS-SCLC) in the second planned interim analysis of the NRG Oncology/Alliance NRG-LU005 clinical trial. These results were recently reported during the Plenary Session of the American Society for Radiation Oncology Annual Meeting in Washington, DC. “While atezolizumab given concurrently with chemoradiation did not improve survival, we have still learned quite a bit from these findings. With the success of the ADRIATIC trial ...

The NRG Oncology NRG-HN005 phase II/III clinical trial did not meet the non-inferiority criteria to proceed to the phase III portion of the study. The phase II portion of the NRG-HN005 evaluated two experimental treatment arms against a control arm for patients with p16-positive (p16+, accepted as a surrogate for HPV+ status), locoregionally advanced oropharyngeal cancer. The interim futility results were recently reported during the Plenary Session of the American Society for Radiation Oncology Annual Meeting in Washington, DC. “This ...

A study carried out at Mount Sinaí Fuster Heart Hospital in New York in collaboration with the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid provides important new information about atherosclerosis, a disease in which lipids (cholesterol) and other substances accumulate in plaques on the arterial wall, causing the vessels to harden and narrow, and increasing the risk of severe cardiovascular conditions.  The study, published in The Journal of the American College of Cardiology (JACC), was led by Dr. Valentín Fuster, Director of the Cardiovascular ...

The progression of atherosclerosis in people who have no symptoms of it is independently associated with the risk of dying from any cause, according to a new study led by researchers from Mount Sinai Fuster Heart Hospital, published September 30 in the Journal of the American College of Cardiology. This research is also the first to show that advanced imaging can detect atherosclerotic disease of the large vessels long before the appearance of symptoms—an approach that could be used worldwide to prevent cardiovascular disease and risk of death. Together, the findings ...

Lily Wang, Professor, Statistics, College of Engineering and Computing (CEC), received funding for the project: “Collaborative Research: Unlocking Complex Heterogeneity in Large Spatial-Temporal Data with Scalable Quantile Learning.” Wang and her collaborator, Huixia Judy Wang, Department Chair and Professor of Statistics at The George Washington University, are developing scalable and efficient quantile learning techniques and theories to address challenges in analyzing large-scale heterogeneous spatial and temporal data. These new analytical techniques will have wide-ranging applications, revolutionizing scientists’ understanding of spatial and temporal ...

Heart transplant patients who live in socioeconomically disadvantaged areas are more likely to experience post-surgical complications and die within five years than patients who live in more advantaged areas, even when those patients were transplanted at topnotch high-volume hospitals, new UCLA research suggests. The findings, to be published September 30 in the peer-reviewed Journal of Heart and Lung Transplantation, the official publication of the International Society for Heart and Lung Transplantation, suggest that a lack of access ...

Researchers at University of California San Diego School of Medicine have identified a new mechanism underlying inflammatory skin diseases, such as psoriasis and seborrheic dermatitis. They found that a protein essential in forming the skin’s protective barrier (ZNF750) also plays a role in controlling inflammation in skin cells, shedding light on why some people are more susceptible to inflammatory skin diseases than others. The study paves the way for more effective and personalized therapies for these debilitating diseases and also offers broader ...

KANSAS CITY, Mo. (September 30, 2024) – The University of Missouri-Kansas City Healthcare Institute for Innovations in Quality and Saint Luke’s Mid America Heart Institute today announced a nationwide, four-year observational study of U.S. pregnant people with cardiovascular disease to better understand and combat maternal mortality and morbidity. The National Heart, Lung, and Blood Institute of the National Institutes of Health awarded more than $7.9 million to the UMKC Healthcare Institute for Innovations in Quality to fund the study, Heart Outcomes in Pregnancy Expectations (HOPE) ...

WASHINGTON, September 30, 2024 — Spiritual beliefs and a historically-based distrust of clinical research may factor into Black patients’ decisions about whether to participate in cancer trials, according to surveys of patients treated at two Baltimore medical centers. Findings will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting.  This cross-sectional, descriptive study found lingering distrust in clinical research among Black patients, despite their self-reported trust in their cancer medical teams. The surveys sought to shed light on what might be contributing to the growing underrepresentation of Black people in cancer trials ...

In a retrospective study of Medicare claims data, researchers found dementia was more frequently diagnosed within one year of a fall compared to other types of injuries. KEY TAKEAWAYS In a retrospective cohort study involving more than 2 million older adults who sustained an injury, 10.6% of patients who experienced a fall were subsequently diagnosed with dementia. Compared to other types of injuries, falls were associated with a 21% increased risk for future dementia diagnosis. Findings support implementing cognitive screenings for older adults who have experienced a fall resulting in an emergency room visit or hospital admission. Researchers ...

About The Study: This study found that female physicians were underrepresented among residents entering high-compensation specialties compared with non–high-compensation specialties. However, while high-compensation surgical specialties experienced a steady increase in the proportion of female applicants and matriculants over time, high-compensation nonsurgical specialties experienced an overall decrease in the proportion of female applicants and no significant changes in the proportion of female matriculants. Corresponding Author: To contact the corresponding author, Karina Pereira-Lima, PhD, ...

Mount Everest is about 15 to 50 metres taller than it would otherwise be because of uplift caused by a nearby eroding river gorge, and continues to grow because of it, finds a new study by UCL researchers. The study, published in Nature Geoscience, found that erosion from a river network about 75 kilometres from Mount Everest is carving away a substantial gorge. The loss of this landmass is causing the mountain to spring upwards by as much as 2 millimetres a year and has already increased its height by between 15 and 50 metres over the past 89,000 years. At 8,849 metres high, Mount Everest, also known as Chomolungma in Tibetan or Sagarmāthā ...

About The Study: Most 3- and 4-year-old children in this pooled analysis did not meet the current World Health Organization guidelines for physical activity, sedentary behavior, and sleep. Priority must be given to understanding factors that influence these behaviors in this age group and to implementing contextually appropriate programs and policies proven to be effective in promoting healthy levels of movement behaviors. Corresponding Author: To contact the corresponding author, Kar Hau Chong, PhD, email khchong@uow.edu.au. To access the embargoed ...

About The Study: This study highlights that progress in reducing excess mortality rates among Black individuals was made primarily in reducing deaths from cancer and cardiovascular diseases among males and from cardiovascular diseases and diabetes among females. However, this progress was stalled or reversed by an increase in mortality from external causes, such as assaults and accidents, as well as a stagnation in advancements against cardiovascular diseases during periods without decrease. Corresponding Author: To contact the corresponding author, Harlan M. Krumholz, ...

About The Study: The findings of this study suggest the enduring effects of systemic racism on present-day health outcomes among persons with HIV. Regardless of their neighborhood’s contemporary level of gentrification, individuals diagnosed with HIV while living in historically redlined neighborhoods may experience a significantly longer time to viral suppression.  Corresponding Author: To contact the corresponding author, John R. Bassler, MS, email jbassle1@uab.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2024.5003) Editor’s ...

Rare diseases, which affect 30 million people across Europe, are entering a new phase in diagnosis and treatment. Key initiatives include the creation of a European registry dedicated to rare diseases and the launch of Europe’s first postgraduate specialization program with academic credit recognition (a second-level master’s degree). This joint degree, offered in collaboration with various European universities, aims to train professionals with expertise in rare disease research.          The team is coordinated by Professor Wanda Lattanzi, Associate Professor of Cellular ...

Embargoed for release: Monday, September 30, 11:00 AM ET Key points: There are no nationally required nutrition competencies within medical education in the U.S. In that context, researchers surveyed a professionally diverse panel of medical and nutrition experts to reach a consensus on proposed nutrition competencies for medical students and physician trainees, as well as recommendations for how to evaluate them.  The proposed competencies directly respond to Congress’ bipartisan resolution H. Res. 1118, which calls for “meaningful physician ...

Earlier this summer, members of the National Center for Supercomputing Applications traveled to Alaska as part of their continued work with the Permafrost Discovery Gateway, a project led by the Woodwell Climate Research Center using artificial intelligence (AI) and machine learning (ML) in tracking Arctic permafrost thaw. NCSA’s Associate Director for Software Kenton McHenry and Research Software Engineer Todd Nicholson visited Fairbanks, Alaska along with 12 Google.org fellows to see first hand the melting permafrost and the impacts to those that live there. “I have seen ...

Rockville, MD. (September 30, 2024) – The 2024 Global Summit and Award Ceremonies for Cancer Research & Entrepreneurship, co-hosted by the National Foundation for Cancer Research (NFCR) and AIM-HI Accelerator Fund, will be held on October 18th at the National Press Club in Washington, DC. This is the one event each year where key leaders from the entire cancer research and patient care ecosystem come together under one roof to share critical discoveries and ideas from all areas of cancer research, drug development, and patient care. This is where many innovative ...

About The Study: In an open-label trial in patients with heart failure with preserved ejection fraction with left ventricular ejection fraction of 60% or greater, mavacamten, a cardiac myosin inhibitor, was associated with improvements in biomarkers of cardiac wall stress and injury, with no sustained reductions in left ventricular ejection fraction observed.  Corresponding Authors: To contact the corresponding authors, email Sanjiv J. Shah, MD, (sanjiv.shah@northwestern.edu) and Scott ...

NEW YORK — The American Federation for Aging Research (AFAR) is pleased to announce the recipient of the 2024 Sagol Network GerOmic Award for Junior Faculty: Amy Vandiver, MD, PhD, Clinical Instructor Clinician-Investigator Track, University of California Los Angeles. Established in 2020, the Sagol Network GerOmic Award for Junior Faculty is a one- to two-year award given to junior faculty (MDs and PhDs) to conduct aging-related Omics (GerOmics) research.  Omics is a rapidly evolving, multi-disciplinary, and emerging field that encompasses genomics, epigenomics, transcriptomics, ...

WASHINGTON, September 30, 2024 — An accelerated course of radiation therapy does not increase complications for patients who undergo breast reconstruction following a mastectomy, new research shows. Findings of the large, phase III RT CHARM trial (Alliance A221505) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. While radiation therapy following mastectomy to remove breast cancer is known to improve survival rates for certain patients who are at higher risk of recurrence, RT CHARM is the first multi-institutional international study to show that a shorter course ...