For decades, numerous investigations have only focused on axon regeneration to restore function after traumatic spinal cord injury (SCI), as interrupted neuronal pathways have to be reconnected for sensorimotor and autonomic recovery to occur. Experimental approaches have ranged from drug delivery and cell transplantation to genetic manipulations. Certainly, it would be an extraordinary achievement for injured axons to regenerate over long distances, to form synapses with target neurons, and to result in dramatic functional improvement. Dr. Shaoping Hou from Drexel University ...

Bethesda, MD (August 6, 2014) – Immunosuppressive drugs called thiopurines have been found to increase the risk of myeloid disorders, such as acute myeloid leukemia and myelodysplastic syndrome, a rare bone marrow disorder, seven-fold among inflammatory bowel disease (IBD) patients. These data were reported in a new study published in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association (AGA). Thiopurines are an established treatment for IBD patients, used to reduce inflammation and provide symptom ...

Evolution of the first burrowing animals may have played a major role in stabilizing the Earth's oxygen reservoir, according to a new study in Nature Geoscience. Around 540 million years ago, the first burrowing animals evolved. When these worms began to mix up the ocean floor's sediments (a process known as bioturbation), their activity came to significantly influence the ocean's phosphorus cycle and as a result, the amount of oxygen in Earth's atmosphere. "Our research is an attempt to place the spread of animal life in the context of wider biogeochemical cycles, ...

New research has identified two significant risk factors associated with painful neurological diseases in the skull shape of the Cavalier King Charles Spaniel (CKCS). The findings could help in tackling these conditions in toy dog breeds and could be used in breeding guidelines. The study conducted by undergraduate student, Thomas Mitchell, from the University of Bristol's School of Veterinary Sciences, and supervised by Dr Clare Rusbridge, is published online in the journal Canine Genetics and Epidemiology. Syringomyelia (SM) is a painful condition in dogs and is ...

Adolescents who behave aggressively are more likely to drink alcohol and in larger quantities than their peers, according to a recent study completed in Finland. Depression and anxiety, on the other hand, were not linked to increased alcohol use. The study investigated the association between psychosocial problems and alcohol use among 4074 Finnish 13- to 18-year-old adolescents. The results were published in Journal of Adolescence. The results indicate that smoking and attention problems also increase the probability of alcohol use. Furthermore, among girls, early menarche ...

An extensive study by Smithsonian scientists presents a synopsis of the carabid beetle tribe Lachnophorini. The research contains a new genus and the remarkable 24 new species added to the tribe. The study was published in the open access journal ZooKeys. Beetles from the family Carabidae, commonly known as ground beetles are a large, cosmopolitan group, with more than 40,000 species worldwide, Carabid beetles range in size from 0.6 mm to 90.2 mm and occur in nature in several fractal universes influencing life therein as predators, ectoparasitoids, seed eaters, and even ...

Fortunately, you are not always what you eat – at least in Canada's Arctic. New research from the University of Guelph reveals that arctic mammals such as caribou can metabolize some current-use pesticides (CUPs) ingested in vegetation. This limits exposures in animals that consume the caribou – including humans. "This is good news for the wildlife and people of the Arctic who survive by hunting caribou and other animals," said Adam Morris, a PhD student in the School of Environmental Sciences and lead author of the study published recently in Environmental Toxicology ...

CAMBRIDGE, MA -- MIT engineers have fabricated a new elastic material coated with microscopic, hairlike structures that tilt in response to a magnetic field. Depending on the field's orientation, the microhairs can tilt to form a path through which fluid can flow; the material can even direct water upward, against gravity. Each microhair, made of nickel, is about 70 microns high and 25 microns wide — about one-fourth the diameter of a human hair. The researchers fabricated an array of the microhairs onto an elastic, transparent layer of silicone. In experiments, the ...

Some young women simply have more resilience and better coping skills and can shrug off the effect of unwanted cat calls, demeaning looks and sexual advances. Women with low resilience struggle and could develop psychological problems when they internalize such behavior, because they think they are to blame. So say Dawn Szymanski and Chandra Feltman of the University of Tennessee in the US, in Springer's journal Sex Roles, after studying how female college students handle the sexually objectifying behavior of men. According to the popular feminist Objectification Theory, ...

Rheumatoid arthritis is a condition that causes painful inflammation of several joints in the body. The joint capsule becomes swollen, and the disease can also destroy cartilage and bone as it progresses. Rheumatoid arthritis affects 0.5% to 1% of the world's population. Up to this point, doctors have used various drugs to slow or stop the progression of the disease. But now, ETH Zurich researchers have developed a therapy that takes the treatment of rheumatoid arthritis in mice to a new level: after receiving the medication, researchers consider the animals to be fully ...

Non-tenure-track academics experience stress, anxiety, and depression due to their insecure job situation, according to the first survey of its kind published in the open-access journal Frontiers in Psychology. There were 1.4 contingent faculty workers in the USA, according to a report by the American Association of University Professors. These faculty members, such as research adjunct faculty, lecturers and instructors, are off the so-called "tenure track". They work under short-term contracts with limited health and retirement benefits, often part-time and at different ...

Two Ignite sessions focusing on findings in the United States National Climate Assesment5 (NCA) will take place on Monday, August 11th during the Ecological Society of America's 99th Annual Meeting, held this year in Sacramento, California. The first session, Ignite 1: From Plains to Oceans to Islands: Regional Findings from the Third National Climate Assessment will highlight major findings from the report about the regional effects of climate change, discuss impacts to the ecosystems of the region, and explore how changes in those ecosystems can moderate or exacerbate ...

Messier 33, otherwise known as NGC 598, is located about three million light-years away in the small northern constellation of Triangulum (The Triangle). Often known as the Triangulum Galaxy it was observed by the French comet hunter Charles Messier in August 1764, who listed it as number 33 in his famous list of prominent nebulae and star clusters. However, he was not the first to record the spiral galaxy; it was probably first documented by the Sicilian astronomer Giovanni Battista Hodierna around 100 years earlier. Although the Triangulum Galaxy lies in the northern ...

ATLANTA – August 6, 2014–Nearly one in ten cancer survivors reports smoking many years after a diagnosis, according to a new study by American Cancer Society researchers. Further, among ten cancer sites included in the analysis, the highest rates of smoking were in bladder and lung cancers, two sites strongly associated with smoking. The study appears early online in Cancer Epidemiology, Biomarkers & Prevention. Cigarette smoking decreases the effectiveness of cancer treatments, increases the probability of recurrence, and reduces survival time. Nonetheless, some studies ...

PHILADELPHIA — Nine years after diagnosis, 9.3 percent of U.S. cancer survivors were current smokers and 83 percent of these individuals were daily smokers who averaged 14.7 cigarettes per day, according to a report in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research (AACR). "We need to follow up with cancer survivors long after their diagnoses to see whether they are still smoking and offer appropriate counseling, interventions, and possible medications to help them quit," said Lee Westmaas, PhD, director of tobacco ...

Promoting a healthy diet from infancy is important to prevent childhood obesity and the onset of chronic disease. This is the finding from a study published in the latest issue of Australian and New Zealand Journal of Public Health. Led by Rebecca Byrne from QUT, the study described quantity and diversity of food and drinks consumed by children aged 12-16 months. "The toddler years are a critical age in the development of long-term food preferences, but this is also the age that autonomy, independence and food fussiness begins," Ms Byrne said. "Childhood obesity in ...

Nutrition has not been given enough priority in national Aboriginal and Torres Strait Islander health policy in recent years. This is the finding from a study published in the latest issue of Australian and New Zealand Journal of Public Health. Led by Jennifer Browne from La Trobe University, the study examined Aboriginal-specific health policies and strategies developed between 2000 and 2012. "Increased inclusion of nutrition in Aboriginal health policy was identified during the first half of this period, but less during the second where a much greater emphasis was ...

HUNTVILLE (8/6/14) -- According to a 2010 survey by the Center for Disease Control and Prevention (CDC), an estimated 1.4 million women in Texas experience stalking during their lifetimes. Despite recent laws adopted in the state to protect stalking victims, little information is available about the crime or policies and procedures to aid the criminal justice system, according to a report from the Crime Victims' Institute (CVI). According to CDC estimates, 15.6 percent of the female population in Texas will experience stalking, slightly less than the 16.2 percent national ...

Researchers in the Vanderbilt University Institute of Imaging Science (VUIIS) have achieved the first conclusive non-invasive measurement of neural signaling in the spinal cords of healthy human volunteers. Their technique, described today in the journal eLife, may aid efforts to help patients recover from spinal cord injuries and other disorders affecting spinal cord function, including multiple sclerosis. "We definitely hope that this work can be translated to address many neurological disorders," said the paper's first author, Robert Barry, Ph.D., a postdoctoral ...

CHAMPAIGN, Ill. — Scientists report they can crank up insect aggression simply by interfering with a basic metabolic pathway in the insect brain. Their study, of fruit flies and honey bees, shows a direct, causal link between brain metabolism (how the brain generates the energy it needs to function) and aggression. The team reports its findings in the Proceedings of the National Academy of Sciences. The new research follows up on previous work from the laboratory of University of Illinois entomology professor and Institute for Genomic Biology director Gene Robinson, ...

From AGU's blogs: Sea-level spikes can harm beaches worse than hurricane Unforeseen, short-term increases in sea level caused by strong winds, pressure changes and fluctuating ocean currents can cause more damage to beaches on the East Coast over the course of a year than a powerful hurricane making landfall, according to a new study. The new research suggests that these sea-level anomalies could be more of a threat to coastal homes and businesses than previously thought, and could become higher and more frequent as a result of climate change, according to a new study ...

In general, our knowledge of biology—and much of science in general—is limited by our ability to actually see things. Researchers who study developmental problems and disease, in particular, are often limited by their inability to look inside an organism to figure out exactly what went wrong and when. Now, thanks to techniques developed at Caltech, scientists can see through tissues, organs, and even an entire body. The techniques offer new insight into the cell-by-cell makeup of organisms—and the promise of novel diagnostic medical applications. "Large volumes of tissue ...

MADISON, Wis. — A team of researchers at the University of Wisconsin-Madison has identified the genes and enzymes that create a promising compound — the 19 carbon furan-containing fatty acid (19Fu-FA). The compound has a variety of potential uses as a biological alternative for compounds currently derived from fossil fuels. Researchers from the Great Lakes Bioenergy Research Center (GLBRC), which is headquartered at UW-Madison and funded by the U.S. Department of Energy, discovered the cellular genomes that direct 19Fu-FA's synthesis and published the new findings Aug. ...

A majority of middle-aged men and women eligible to take aspirin to prevent heart attack and stroke do not recall their doctors ever telling them to do so, according to a University of Rochester study of a national sample of more than 3,000 patients. Published online by the Journal of General Internal Medicine, the finding illustrates a common disconnect between public health guidelines and what occurs in clinical practice. The UR study is consistent with other research showing that physicians often do not recommend aspirin as prevention therapy to the general population, ...

Among people with type 2 diabetes, eating pistachios may reduce the body's response to the stresses of everyday life, according to Penn State researchers. "In adults with diabetes, two servings of pistachios per day lowered vascular constriction during stress and improved neural control of the heart," said Sheila G. West, professor of biobehavioral health and nutritional sciences. "Although nuts are high in fat, they contain good fats, fiber, potassium and antioxidants. Given the high risk of heart disease in people with diabetes, nuts are an important component of a ...