Microchip reveals how tumor cells transition to invasion
2014-08-17
VIDEO:
Cancer cells advance across a microchip designed to be an obstacle course for cells. The device sheds new light on how cancer cells invade and could be used to test...
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PROVIDENCE, R.I. [Brown University] — Using a microengineered device that acts as an obstacle course for cells, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body.
The epithelial-mesenchymal transition ...
'Cavity protection effect' helps to conserve quantum information
2014-08-17
The electronics we use for our computers only knows two different states: zero or one. Quantum systems on the other hand can be in different states at once, they can store a superposition of "zero" and "one". This phenomenon could be used to build ultrafast quantum computers, but there are several technological obstacles that have to be overcome first. The biggest problem is that quantum states are quickly destroyed due to interactions with the environment. At TU Wien (Vienna), scientists have now succeeded in using a protection effect to enhance the stability of a particularly ...
FDA-approved drug restores hair in patients with Alopecia Areata
2014-08-17
NEW YORK, NY (August 17, 2014) —Researchers at Columbia University Medical Center (CUMC) have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients.
The results appear in today's online issue of Nature Medicine.
In the paper, the researchers report initial results from an ongoing clinical trial of the drug, which has produced complete hair regrowth ...
Fascinating rhythm: Light pulses illuminate a rare black hole
2014-08-17
The universe has so many black holes that it's impossible to count them all. There may be 100 million of these intriguing astral objects in our galaxy alone. Nearly all black holes fall into one of two classes: big, and colossal. Astronomers know that black holes ranging from about 10 times to 100 times the mass of our sun are the remnants of dying stars, and that supermassive black holes, more than a million times the mass of the sun, inhabit the centers of most galaxies.
But scattered across the universe like oases in a desert are a few apparent black holes of a more ...
A shift in the code: New method reveals hidden genetic landscape
2014-08-17
Cold Spring Harbor, NY – With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health. In fact, such insertions and deletions can dramatically alter biological function, leading to diseases from autism to cancer. Still, it is has been difficult to detect these mutations. Now, a team of scientists at Cold Spring Harbor Laboratory (CSHL) has devised a new way to analyze genome sequences that pinpoints so-called insertion and deletion mutations (known as "indels") ...
New home for an 'evolutionary misfit'
2014-08-17
One of the most bizarre-looking fossils ever found - a worm-like creature with legs, spikes and a head difficult to distinguish from its tail – has found its place in the evolutionary Tree of Life, definitively linking it with a group of modern animals for the first time.
The animal, known as Hallucigenia due to its otherworldly appearance, had been considered an 'evolutionary misfit' as it was not clear how it related to modern animal groups. Researchers from the University of Cambridge have discovered an important link with modern velvet worms, also known as onychophorans, ...
Stem cells reveal how illness-linked genetic variation affects neurons
2014-08-17
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Human neurons firing
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A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports. The study, led by Guo-li Ming, M.D., Ph.D., and Hongjun Song, Ph.D., of the Johns Hopkins University School of Medicine and described online Aug. 17 in the journal Nature, used stem cells generated from people with and without mental illness ...
New Stanford research sheds light on how children's brains memorize facts
2014-08-17
As children learn basic arithmetic, they gradually switch from solving problems by counting on their fingers to pulling facts from memory. The shift comes more easily for some kids than for others, but no one knows why.
Now, new brain-imaging research gives the first evidence drawn from a longitudinal study to explain how the brain reorganizes itself as children learn math facts. A precisely orchestrated group of brain changes, many involving the memory center known as the hippocampus, are essential to the transformation, according to a study from the Stanford University ...
Suspect gene corrupts neural connections
2014-08-17
Researchers have long suspected that major mental disorders are genetically-rooted diseases of synapses – the connections between neurons. Now, investigators supported in part by the National Institutes of Health have demonstrated in patients' cells how a rare mutation in a suspect gene disrupts the turning on and off of dozens of other genes underlying these connections.
"Our results illustrate how genetic risk, abnormal brain development and synapse dysfunction can corrupt brain circuitry at the cellular level in complex psychiatric disorders," explained Hongjun Song, ...
Stuck in neutral: Brain defect traps schizophrenics in twilight zone
2014-08-17
People with schizophrenia struggle to turn goals into actions because brain structures governing desire and emotion are less active and fail to pass goal-directed messages to cortical regions affecting human decision-making, new research reveals.
Published in Biological Psychiatry, the finding by a University of Sydney research team is the first to illustrate the inability to initiate goal-directed behaviour common in people with schizophrenia.
The finding may explain why people with schizophrenia have difficulty achieving real-world goals such as making friends, completing ...
Virginity pledges for men can lead to sexual confusion -- even after the wedding day
2014-08-17
Bragging of sexual conquests, suggestive jokes and innuendo, and sexual one-upmanship can all be a part of demonstrating one's manhood, especially for young men eager to exert their masculinity.
But how does masculinity manifest itself among young men who have pledged sexual abstinence before marriage? How do they handle sexual temptation, and what sorts of challenges crop up once they're married?
"Sexual purity and pledging abstinence are most commonly thought of as feminine, something girls and young women promise before marriage," said Sarah Diefendorf, a sociology ...
Study finds range of skills students taught in school linked to race and class size
2014-08-17
SAN FRANCISCO -- Pressure to meet national education standards may be the reason states with significant populations of African-American students and those with larger class sizes often require children to learn fewer skills, finds a University of Kansas researcher.
"The skills students are expected to learn in schools are not necessarily universal," said Argun Saatcioglu, a KU associate professor of education and courtesy professor of sociology.
In effort to increase their test scores and, therefore, avoid the negative consequences of failing to meet the federal standards ...
Study suggests federal law to combat use of 'club drugs' has done more harm than good
2014-08-17
SAN FRANCISCO — A federal law enacted to combat the use of "club drugs" such as Ecstasy — and today's variation known as Molly — has failed to reduce the drugs' popularity and, instead, has further endangered users by hampering the use of measures to protect them.
University of Delaware sociology professor Tammy L. Anderson makes that case in a paper she will present at the 109th Annual Meeting of the American Sociological Association. The paper, which has been accepted for publication this fall in the American Sociological Association journal Contexts, examines the unintended ...
Risky situations increase women's anxiety, hurt their performance compared to men
2014-08-17
SAN FRANCISCO — Risky situations increase anxiety for women but not for men, leading women to perform worse under these circumstances, finds a study to be presented at the 109th Annual Meeting of the American Sociological Association.
"On the surface, risky situations may not appear to be particularly disadvantageous to women, but these findings suggest otherwise," said study author Susan R. Fisk, a doctoral candidate in sociology at Stanford University, who defines a risky situation as any setting with an uncertain outcome in which there can be both positive or negative ...
Most temporary workers from Mexico no better off than undocumented workers
2014-08-17
SAN FRANCISCO -- Many politicians see the temporary worker program in the U.S. as a solution to undocumented immigration from Mexico. But an Indiana University study finds that these legal workers earn no more than undocumented immigrants, who unlike their legal counterparts can improve their situation by changing jobs or negotiating for better pay.
"Just because temporary workers are legally present in the country does not mean that they will have better jobs or wages than undocumented workers," said Lauren Apgar, lead researcher of the study "Temporary Worker Advantages? ...
Bone chemistry reveals royal lifestyle of Richard III
2014-08-17
Oxford, August 17, 2014 - A recent study by the British Geological Survey, in association with researchers at the University of Leicester, has delved into the bone and tooth chemistry of King Richard III and uncovered fascinating new details about the life and diet of Britain's last Plantagenet king. The study, published in Elsevier's Journal of Archaeological Science indicates a change in diet and location in his early childhood, and in later life, a diet filled with expensive, high status food and drink. This forensic study, the most complete to have been conducted on ...
'Getting-by girls' straddle gap between academic winners and losers
2014-08-17
Everyone notices the academic superstars and failures, but what about the tens of millions of American teens straddling these two extremes? A new study from the University of California, Berkeley, has spotlighted a high school subculture that has made an art of slacking – even with ample educational resources – and may be destined to perpetuate the nation's struggling lower-middle class.
UC Berkeley sociologist Michele Rossi studied white teenage girls in their last year of a well-funded high school. What she found was a group she dubbed "getting-by girls," whose coping ...
Study identifies factors that contribute to food trucks' fast spread
2014-08-16
ANN ARBOR---They're not your father's lowbrow roach coaches serving up greasy burgers and bad dogs. Today's gourmet food trucks peddle sushi, hybrid Korean tacos and other dishes that combine different types of cuisine to create a highbrow dining experience for foodies in search of eclectic, local eats.
That's the take of researchers from the University of Michigan and Northwestern University who harvested Twitter data to conduct a de facto census of up-scale U.S. food trucks, invented in Los Angeles in 2008.
"Virtually all these trucks are online and use Twitter to ...
Middle-aged women missing passion (and sex) seek affairs, not divorce
2014-08-16
SAN FRANCISCO — When middle-aged women seek extra-marital affairs, they are looking for more romantic passion, which includes sex — and don't want to divorce their husbands, suggests new research to be presented at the 109th Annual Meeting of the American Sociological Association.
"Being happy in marriage is far different than being happy in bed," said Eric Anderson, a professor of masculinity, sexuality, and sport at the University of Winchester in England and the chief science officer at AshleyMadison.com, a popular website for those interested in having extra-marital ...
For men in pink-collar jobs, a tradeoff: Lower pay, more job security
2014-08-16
SAN FRANCISCO — Is a man without a four-year college degree better off trying to land a well-paying but insecure job in traditionally male fields such as manufacturing or construction, or should he consider lower-paying but steadier employment in a female-dominated field?
Janette Dill, a University of Akron sociology professor, and her colleagues try to answer that question in a new study she will present at the 109th Annual Meeting of the American Sociological Association.
"It's such a hard labor market if you don't have a college degree," Dill says. "You're just ...
Parental incarceration can be worse for a child than divorce or death of a parent
2014-08-16
SAN FRANCISCO — With more than 2 million people behind bars, the U.S. has the highest incarceration rate in the world. This mass incarceration has serious implications for not only the inmates, but their children, finds a new University of California-Irvine study. The study found significant health problems, including behavioral issues, in children of incarcerated parents and also that, for some types of health outcomes, parental incarceration can be more detrimental to a child's well-being than divorce or the death of a parent.
"We know that poor people and racial minorities ...
Peers, but not peer pressure, key to prescription drug misuse among young adults
2014-08-16
SAN FRANCISCO — Current efforts to prevent prescription drug misuse among young adults need to consider peers — but not peer pressure — according to a Purdue University study.
"With the 18-29 age group we may be spending unnecessary effort working a peer pressure angle in prevention and intervention efforts. That does not appear to be an issue for this age group," said study co-author Brian Kelly, a professor of sociology and anthropology who studies drug use and youth cultures. "Rather, we found more subtle components of the peer context as influential. These include ...
Disconnect between parenting and certain jobs a source of stress, study finds
2014-08-16
SAN FRANCISCO — Some working parents are carrying more psychological baggage than others — and the reason has nothing to do with demands on their time and energy.
The cause is their occupation.
According to University of Iowa researchers, parents who hold jobs viewed by society as aggressive, weak, or impersonal are likely to be more stressed out than parents whose occupations are seen in a light similar to parenting — good, strong, and caring.
"We know that one source of stress for parents is the time and energy bind," says Mark Walker, a doctoral student in sociology ...
Ethnoburbs: Segregation in suburbia
2014-08-16
White flight does not end when residents move from poor urban neighborhoods to the suburbs. An Indiana University study found that white flight from one suburban neighborhood to another occurs when white residents move away from "ethnoburbs," suburban neighborhoods that attract a growing number of middle-class minority residents.
"The sheer force of immigration and suburbanization has resulted in the unmistakable rise of middle-class yet ethnic suburban communities. However, my research shows that despite their distinct middle-class character, ethnoburbs have lost a steady ...
The notion of love can lead to greater acceptance of couples' rights
2014-08-16
SAN FRANCISCO -- An Indiana University study found that how "in love" a romantic couple appears to be is interpreted differently based on the couple's sexual orientation, affecting what formal and informal rights people think that couple deserves.
Long Doan, a doctoral student in the Department of Sociology at IU Bloomington's College of Arts and Sciences, said the study was created to understand how people's attitudes differ based on sexual orientation.
"If you ask what someone thinks of a same-sex couple or what they think of a straight couple, they usually have different ...
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