CAMBRIDGE, MA -- Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, described in the March 30 issue of Nature Biotechnology, offer the first evidence that this gene-editing technique, known as CRISPR, can reverse disease symptoms in living animals. CRISPR, which offers an easy way to snip out mutated DNA and replace it with the correct sequence, holds potential for treating many genetic disorders, according to the research team. "What's exciting about ...

Pioneering new research from the University of Exeter could have a major impact on climate and environmental science by drastically transforming the perceived reliability of key observations of precipitation, which includes rain, sleet and snow. The ground breaking study examines the effect that increased aerosol concentrations in the atmosphere, emitted as a result of burning fossil fuels, had on regional temperature and precipitation levels. Scientists from Exeter's Mathematics department compared observed regional temperature and precipitation changes throughout ...

Researchers have discovered that mutations in a specific gene are responsible for a hereditary form of melanoma. Every year in the UK, almost 12,000 people are diagnosed with melanoma, a form of skin cancer. About 1 in 20 people with melanoma have a strong family history of the disease. In these patients, pinpointing the genetic mutations that drive disease development allows dermatologists to identify people who should be part of melanoma surveillance programmes. The team found that people with specific mutations in the POT1 gene were extremely likely to develop melanoma. ...

JUPITER, FL, March 30, 2014 – At first glance, measuring what the common fruit fly eats might seem like a trivial matter, but it is absolutely critical when it comes to conducting studies of aging, health, metabolism and disease. How researchers measure consumption can make all the difference in the accuracy of a study's conclusions. Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed what amounts to a best practices guide to the most accurate way of measuring fruit fly food consumption that could lead to more informed research and ...

Researchers at the Intermountain Medical Center Heart Institute in Murray, Utah, have discovered that elevated levels of two recently identified proteins in the body are inflammatory markers and indicators of the presence of cardiovascular disease. These newly identified markers of inflammation, GlycA and GlycB, have the potential to contribute to better understanding of the inflammatory origins of heart disease and may be used in the future to identify a heart patient's future risk of suffering a heart attack, stroke, or even death. Inflammation occurs in the body ...

Among patients undergoing aortic valve replacement using a catheter tube, a comparison of two types of heart valve technologies, balloon-expandable or self-expandable valve systems, found a greater rate of device success with the balloon-expandable valve, according to a JAMA study released online to coincide with presentation at the 2014 American College of Cardiology Scientific Sessions. Transcatheter aortic valve replacement (TAVR) has emerged as a new option for patients with severe narrowing of the aortic valve and as an effective alternative treatment method to ...

Use of the drug aleglitazar, which has shown the ability to lower glucose levels and have favorable effects on cholesterol, did not reduce the risk of cardiovascular death, heart attack or stroke among patients with type 2 diabetes and recent heart attack or unstable angina, according to a JAMA study released online to coincide with presentation at the 2014 American College of Cardiology Scientific Sessions. Cardiovascular disease remains the dominant cause of death among patients with type 2 diabetes. No drug therapy specifically directed against diabetes nor strategy ...

Puritas Organic Gold, the official hydration sponsor of actress/singer/TV personality Lauren Mayhew, announces her "WHAT IS LOVE" video will debut on FOX Sports homepage April 8th, and be televised nationwide on April 9th on FOX's "UFC Tonight." Puritas Organic Gold is the only USDA certified organic fulvic-infused, naturally stable 9.5pH high alkaline water, which meets or exceeds standards for kosher and vegan, contains more than 77 trace minerals and provides superior hydration. "We are thrilled to be able to support Lauren Mayhew's newest video, while also increasing ...

Recent controversy erupted after an unknowing breastfeeding mum was blasted with derogatory comments after being secretly photographed breastfeeding her 8 months old baby in public. The image went viral after being published on social media website, facebook, yet received a deluge of support which became the catalyst for a pro-breastfeeding campaign in Rugeley. To show their support for the rights of breastfeeding mums, 'Neuner's' are showing a united front with one of their stockists, Peak Health Food, by supplying the Rugeley store with hundreds of free samples of ...

Mr. Robert L. Parker has started his new adventure by producing and directing his own movie from his book, "The Awakening of A Troubled Mind!" He said he has gotten so many positive responses from the book that he decided to shoot the movie/fim on it. The Casting Calls are due to be administered on April 5, 2014 from 1-4pm at Next Level Complex at 5070 Raleigh Lagrange Rd, Memphis, Tn. He says that this will be a big break for Memphis to really get on the map with the movie scene! The plans for this movie goes far beyond to what is expected and is looking to be a huge success! ...

The Engineering and Science University Magnet School (ESUMS), an innovative STEM school in the New Haven Public School District, is celebrating the announcement of its first Student Innovation Expo Mini event that will take place on April 8, 2014. The event is open to the general public, and will take place on their temporary campus at 130B Leeder Hill Drive in Hamden, Connecticut. The school has enlisted educators, college professors, and industry professionals to judge the projects and provide feedback to the student groups. The winners of this event will move forward ...

According to one of the nation's leading movers, the 2013 Atlas Van Lines Migration Patterns study found the majority of the country achieved a balance between inbound and outbound moves while the total number of moves increased six percent from 2012. Having started in 1993, Atlas conducts the annual study to track the nation's interstate (or between states) moving patterns year to year. Two states that were outbound in 2012 are now balanced states, Vermont and West Virginia. Formerly inbound states Alaska and Washington also became balanced. After spending 2012 as balanced ...

Next-generation POS retail software system pioneer LightSpeed and Montreal yoga instructor Jennifer Kruidbos, MA, are streamlining corporate wellness with a partnership that will offer in-office yoga classes to LightSpeed employees. LightSpeed, currently Quebec's fastest growing company, has been streamlining the retail world with a comprehensive suite of retail tools for the iGeneration. Winner of the Next-Gen Retail Award and two-time recipient of the Profit 200 award (2011 and 2012), LightSpeed is blazing new technology trails. The recent partnership between Jennifer ...

The research and development department at Antennas Direct is ruled by a mantra: let's make our best antennas even better. The latest example of this commitment to excellence is the new ClearStream 2V. Even after being named the Best HDTV Antenna for Cities by Wired Magazine, Antennas Direct has made enhancements to the award-winning antenna. "The cable companies may turn a deaf ear to their customers, but we love to listen," said Richard Schneider, president of Antennas Direct. "Customers reached out to us, we took their comments about our products and redesigned them ...

Using MRI and X-ray images, Dr. Anand P. Lalaji of Inside Injuries provides avid baseball fans with an "inside" scoop on baseball injuries leading up to the much anticipated Opening Day: March 31, 2014 and throughout the season. Dr. Lalaji, a former baseball player and sports aficionado, created Inside Injuries to provide casual sports fans and diehard enthusiasts alike with the chance to establish a stronger connection with their favorite players and celebrities. "As fans, we are driven to connect with famous people--it's just human nature," said Dr. Lalaji. "Inside ...

UniKey, the industry leader in smart access control technology, announced today that it has released updates to the firmware in the Kevo lock, enabling quicker and easier calibration, performance and speed enhancements, as well as security updates. With more than 100,000 units shipped, Kevo powered by UniKey remains the only keyless Bluetooth residential door lock on the market. UniKey continues to make its access control solution more convenient than any other traditional lock, while also eliminating the need for keys, PINs and passwords, without compromising design ...

As a national provider of multilingual nurse triage and health education services for nearly five million lives each year - including many parents and their children -- the RNs at NurseWise have put together some tips to help guide in your search for the best pediatrician for your family. • Create a provider list. During the beginning stages of your search - whether it be due to pregnancy, relocation or another reason-- set out with the goal of identifying seven to 10 pediatric providers or practices to review thoroughly. Set a hard deadline for finalizing your top provider ...

The invitational event will be held at the Holiday Inn Bangkok Sukhumvit 22 on March 30 and will be run by DAE Thailand to educate local timeshare owners on the full advantages available to them through their holiday ownership. Daniel Chou, Director of DAE Thailand said DAE members and timeshare owners would benefit from the friendly information session that has worked well in other DAE regions. "We look forward to welcoming Thai timeshare owners to this informal session to bring them up to date with all the wonderful things their holiday ownership entitles them ...

The Russell Bedford accounting network has published the Spring 2014 edition of its twice-yearly Business World magazine, a publication aimed primarily at owners and managers of small and medium-sized enterprises. Business World delivers views, analysis and guidance written by specialists from within the Russell Bedford network, together with guest authors from other organisations. Articles in the Spring 2014 edition are: - Poland - developing business opportunities. Poland has become increasingly attractive as a place to do business. Lower taxes, a skilled workforce, ...

The Loway Company, known for the developent of the QueueMetrics call-center suite, released its first call-centre customer satisfaction survey as a free eBook. According to their corporate philosophy that binds accurate data measurement to relevant business improvements, the Swiss company sent to their customers a survey about the usage of Asterisk and QueueMetrics for their daily needs in call-centers management, analysis and statistics. This was done to assess the perceived needs of existing customers so that future improvements could be prioritized. This is the first ...

When one reads articles in the US Media that depict Palestinians living in abject poverty, suffering harassment constantly by the Israelis, the astute reader soon learns that this information is not always accurate. It doesn't really take much research to bring to light the readily available history and current events that give a solid rebuttal to these claims. "The Obama Administration," Attanasio stated, "recently gave the Palestinian Authority (PA) 450 million dollars. This is in addition to 950 million dollars that has been given outright to the PA over the past ...

Bahia Principe is proud to announce that once again it has been awarded the prestigious Blue Flag. The award is a reflection of Bahia Principe's commitment to environmental protection and sustainability. Each Bahia Principe strives to teach guests and staff members about the importance of conservation. Bahia Principe's recognition by the Foundation of Education Environmental reiterates the high standard of water, beaches, and safety found at a Bahia Principe Resort. The Blue Flag award was given to Bahia Principe Bavaro, Grand Bahia Principe La Romana, Grand Bahia Principe ...

BPMonline, the world's fastest growing vendor of CRM + BPM cloud solutions, for the third year running has been recognized as the one that impacts the CRM market, as it was mentioned in Paul Greenberg's review for CRM Watchlist 2014, published on ZDNet.com. It has become a good tradition to stay under CRM industry most prominent thought leader's vigilant eye. The 2014 is not an exception as highlighted in Paul Greenberg's recently issued review. Paul describes BPMonline as a company that 'has grown, become more of an impact player, and continues to develop what has become ...

Paul W. Bohn, Arthur J Schmitt Professor of Chemical & Biomolecular Engineering, University of Notre Dame, to give a presentation titled "Tight Coupling of Chemical Sensing and Reactivity in Nanofluidic Architectures" at the Inaugural Bioanalytical Sensors Conference, May 22 & 23, 2014 in Cambridge, MA. Paul Bohn received his Ph.D. in Chemistry from the University of Wisconsin-Madison. He subsequently joined the faculty at the University of Illinois at Urbana-Champaign, where he served in numerous roles, including Head of the Chemistry Department, Director of ...

Today, Greg Miller, CEO of MagicKitchen.com announced a new partner in the MagicKitchen.com Local Partner Program for North and South Carolina. "Our new Partner Hearthside Home Care in Greensboro, North Carolina will represent our full line of HomeStyle and Special Diets menu items to the full spectrum of residential and commercial prepared meal customers in both North and South Carolina." said Greg Miller. MagicKitchen.com customers include Healthcare Organizations and Health Plans, specialized medical facilities such as clinics, dialysis centers, assisted living facilities, ...