The world's most expensive coffee can cost $80 a cup, and scientists now are reporting development of the first way to verify authenticity of this crème de la crème, the beans of which come from the feces of a Southeast Asian animal called a palm civet. Their study appears in ACS' Journal of Agricultural and Food Chemistry. Eiichiro Fukusaki and colleagues point out that Kopi Luwak (Indonesian for "civet coffee") is the world's costliest coffee, often fetching $150-$200 per pound. Palm civets eat coffee berries, digest the soft fruit surrounding the bean and excrete the ...

A group of international experts from government, industry and academia have concluded that alternative testing strategies (ATSs) that don't rely on animals will be needed to cope with the wave of new nanomaterials emerging from the boom in nanoscience and nanotechnology. Their consensus statement from a workshop on the topic appears in the journal ACS Nano. Andre Nel and colleagues explain that many new engineered nanomaterials (ENMs) are appearing in laboratories, factories and consumer products as a result of advances in nanoscience and nanotechnology. These fields ...

The Fukushima Daiichi nuclear disaster spread significant radioactive contamination over more than 3500 square miles of the Japanese mainland in the spring of 2011. Now several recently published studies of Chernobyl, directed by Timothy Mousseau of the University of South Carolina and Anders Møller of the Université Paris-Sud, are bringing a new focus on just how extensive the long-term effects on Japanese wildlife might be. Their work underscores the idea that, in the wake of the Chernobyl catastrophe in 1986, there have been many lost opportunities to better understand ...

Almost 80 percent of air pollution involving soot that spreads from China over large areas of East Asia — impacting human health and fostering global warming — comes from city traffic and other forms of fossil-fuel combustion, such as home cooking with coal briquettes. That's the conclusion of a study in ACS' journal Environmental Science & Technology, which resolves long-standing questions about sources of air pollution responsible for Asia's infamous atmospheric brown clouds. Örjan Gustafsson and colleagues from China, South Korea and the United States point out in ...

For the first time in more than 100 years, drug and dietary supplement manufacturers are updating the tests used to ensure that their products contain safe levels of metal impurities, and the stringent new requirements, instruments and costs are the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society. Ann Thayer, C&EN senior correspondent, explains that in 1905, the nonprofit standards-setting U.S. Pharmacopeial Convention (USP) first introduced ...

PROVIDENCE, R.I. [Brown University] — Psychotherapy has issues. Evidence shows that some psychosocial treatments work well for common mental health problems such as anxiety and depression and that consumers often prefer them to medication. Yet the use of psychotherapy is on a clear decline in the United States. In a set of research review papers in the November issue of the journal Clinical Psychology Review, now available online, psychologists put psychotherapy on the proverbial couch to examine why it's foundering. Their diagnosis? Much as in many human patients, psychotherapy ...

Contact: Cassandra Aviles cmaviles@partners.org 617-724-6433 Sue McGreevey smcgreevey@partners.org 617 724-2764 Massachusetts General Hospital Use of tPA for ischemic stroke nearly doubled from 2003 to 2011 Clot-dissolving drug administered to greater variety of patients, still not fully utilized Use of the "clot-busting" drug tissue plasminogen activator (tPA) to treat patients with strokes caused by a blockage of blood flow nearly doubled between 2003 and 2011. In their paper receiving online release in the journal Circulation: Cardiovascular Quality and ...

IRVINE, Penn., August 21, 2013 – Efforts to conserve declining populations of forest-interior birds have largely focused on preserving the mature forests where birds breed, but a U.S. Forest Service study suggests that in the weeks leading up to migration, younger forest habitat may be just as important. In an article published recently in the American Ornithologist Union's publication "The Auk," research wildlife biologist Scott Stoleson of the U.S. Forest Service's Northern Research Station suggests that forest regrowth in clearcuts may be vital to birds as they prepare ...

NEW YORK (August 21, 2013) — It turns out that alligators do not live on meat alone. Neither do Nile crocodiles. A new study led by the Wildlife Conservation Society says that the American alligator and a dozen other crocodile species enjoy an occasional taste of fruit along with their normal meat-heavy diets of mammals, birds, and fish. The study gives new insight into the possible role that crocodilians, some of which have large territories, may play in forest regeneration through digesting and passing seeds from fruits. The study appears in the July issue of the ...

Fires that started in July continue on in late August in Idaho and Montana. Actively burning areas, detected by the Moderate Resolution Imaging Spectroradiometer's (MODIS) thermal bands, are outlined in red. The Gold Pan complex fire in Idaho near the Bitterroot National Forest began on July 16, 2013 with a lightning strike. So far 27,000 acres have burned and the fire crews have not yet been able to contain the spread of the fire. Resources on the fire include 17 engines, 4 helicopters, 4 crews, and 4 water tenders (approximately 233 personnel). Unfortunately the ...

PHILADELPHIA — A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his team from the Perelman School of Medicine at the University of Pennsylvania, discovered an entirely new aspect of the gene-splicing process that produces messenger RNA (mRNA). The investigators found that a scarce, small RNA, called U6atac, controls the expression of hundreds of genes that have critical functions in cell growth, cell-cycle ...

Men with neurotic personality traits are having fewer children compared to previous generations, according to a new study published in the European Journal of Personality. The study examined the effect of personality on how likely a person is to have children, using extensive survey and birth registry data from Norway. It also found that men who are extraverted and open tend to have more children, while women who rank as conscientious on personality tests tend to have fewer children, although these findings were constant across generations. The study could have important ...

This news release is available in German. Genome researchers from Bielefeld University's Center for Biotechnology (CeBiTec) headed by Professor Dr. Alfred Pühler have succeeded in sequencing the genome of the Chinese hamster. The Chinese hamster supplies the cell cultures used by the pharmaceutical industry to produce biopharmaceutical products such as antibodies used in medicine. This costly project was only possible thanks to a cooperation between Bielefeld University and its international project partners. The researchers have now published their results in the ...

Amsterdam, NL, 21 August 2013 – Metals such as iron, copper, and zinc are important for many biological processes. In recent years, studies have shown that these nutritionally-essential metals are elevated in human Alzheimer's disease (AD) brains and some animal models of AD. Scientists are now exploring whether these metals are causing the neurodegeneration seen in AD or are indicative of other ongoing pathologic processes. In a new study, investigators used synchrotron x-ray fluorescence microscopy to image metal ions in the brain, focusing on the amyloid plaques that ...

NASA's Terra satellite captured an image of Typhoon Trami's center just north of Taiwan as it headed for landfall in eastern China. On Aug. 21 at 02:45 UTC/10:45 p.m. EDT on Aug. 20, NASA's Terra satellite passed over the Northwestern Pacific Ocean and the Moderate Resolution Imaging Spectroradiometer or MODIS instrument that flies aboard it, captured a visible image of Trami. The MODIS image showed a tight circulation center with bands of thunderstorms have wrapped more tightly into the center of circulation from the north to east to south of the center. The band of ...

(WASHINGTON, August 21, 2013) – New research suggests that restricting calories for a defined period of time may improve the success of cancer treatment, offering valuable new data on how caloric intake may play a role in programmed cancer cell death and efficacy of targeted cancer therapies. Study results were published online today in Blood, the Journal of the American Society of Hematology (ASH). While previous studies suggest a connection between caloric intake and the development of cancer, scientific evidence about the effect of caloric intake on the efficacy of ...

The small size and abnormal anatomy of children born with heart defects often force doctors to place lifesaving defibrillators entirely outside the heart, rather than partly inside — a less-than-ideal solution to dangerous heart rhythms that involves a degree of guesstimating and can compromise therapy. Now, by marrying simple MRI images with sophisticated computer analysis, a team of Johns Hopkins researchers says it may be possible to take the guesswork out of the process by using a virtual 3-D heart model that analyzes a child's unique anatomy and pinpoints the best ...

CAMBRIDGE, MA -- Anxiety disorders, which include posttraumatic stress disorder, social phobias and obsessive-compulsive disorder, affect 40 million American adults in a given year. Currently available treatments, such as antianxiety drugs, are not always effective and have unwanted side effects. To develop better treatments, a more specific understanding of the brain circuits that produce anxiety is necessary, says Kay Tye, an assistant professor of brain and cognitive sciences and member of MIT's Picower Institute for Learning and Memory. "The targets that current ...

A 100% genetic match for Middle East Respiratory Syndrome (MERS) has been discovered in an insect-eating bat in close proximity to the first known case of the disease in Saudi Arabia. The discovery points to the likely animal origin for the disease, although researchers say that an intermediary animal is likely also involved. Led by team of investigators from the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, EcoHealth Alliance, and the Ministry of Health of the Kingdom of Saudi Arabia, the study is the first to search ...

(Santa Barbara, Calif.) –– Fruit flies have a lot to teach us about the complexity of food. Like these tiny little creatures, most animals are attracted to sugar but are deterred from eating it when bitter compounds are added. A new study conducted by UC Santa Barbara's Craig Montell, Duggan Professor of Neuroscience in the Department of Molecular, Cellular and Developmental Biology, explains a breakthrough in understanding how sensory input impacts fruit flies' decisions about sweet taste. The findings were published today in the journal Neuron. It is generally well ...

Infection during a newborn's first 7 days of life is associated with bacterial infection or colonization in the mother Early-onset neonatal infection, defined as infection in the first 7 days of life, is associated with maternal infection and colonization, a systematic review and meta-analysis by Grace Chan (Johns Hopkins School of Public Health) and colleagues found in this week's issue of PLOS Medicine. Newborns of mothers with laboratory-confirmed infection had an odds ratio of 6.6 (95%CI 3.9-11.2) for laboratory-confirmed infection themselves compared with newborns ...

Mental health conditions contribute to approximately 14% of the total global burden of disease but there is a substantial treatment gap in both developed and developing countries. Treatment of mental health conditions in low resource settings such as Nigeria, one of Africa's most populous countries, is particularly challenging where that are few mental health professionals. For example Nigeria has a population of ~150 million but only 0.06 psychiatrists and 0.02 psychologists per 100,000 people. In order to address the treatment gap the World Health Organization (WHO) ...

Research at the University of Liverpool has shown that the mechanisms of the human foot are not as unique as originally thought and have much more in common with the flexible feet of other great apes. Current understanding of the evolution of human walking is based on research from the 1930s, which proposes that human feet function very differently to those of other apes, due to the development of arches in the mid-foot region and the supposed rigidity of that on the outside edge of the foot. In a study of more than 25,000 human steps made on a pressure-sensitive treadmill ...

OAKLAND, Calif., August 20, 2013 — Kaiser Permanente Northern California nearly doubled the rate of blood pressure control among adult members with diagnosed hypertension between 2001 and 2009 through one of the largest, community-based hypertension programs in the nation, as reported today in the Journal of the American Medical Association. The rate of hypertension control throughout Kaiser Permanente Northern California increased from 43.6 in 2001 to 80.4 percent in 2009, as measured by the Healthcare Effectiveness Data and Information Set quality measurement set by ...

Implementation of a large-scale hypertension program that included evidence-based guidelines and development and sharing of performance metrics was associated with a near-doubling of hypertension control between 2001 and 2009, compared to only modest improvements in state and national control rates, according to a study in the August 21 issue of JAMA. "Hypertension affects 65 million adults in the United States (29 percent) and is a major contributor to cardiovascular disease. Although effective therapies have been available for more than 50 years, fewer than half of ...