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Toxic nanoparticles might be entering human food supply

2013-08-23
COLUMBIA, Mo. – Over the last few years, the use of nanomaterials for water treatment, food packaging, pesticides, cosmetics and other industries has increased. For example, farmers have used silver nanoparticles as a pesticide because of their capability to suppress the growth of harmful organisms. However, a growing concern is that these particles could pose a potential health risk to humans and the environment. In a new study, researchers at the University of Missouri have developed a reliable method for detecting silver nanoparticles in fresh produce and other food ...

Harvard Stem Cell researchers create cells that line blood vessels

2013-08-23
In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels—called vascular endothelial cells—from human induced pluripotent stem cells (iPSCs), revealing new details about how these cells function. Using a unique approach, the researchers induced the differentiation of specific cell types by generating mechanical forces on the surface of the iPSC-derived endothelium mimicking the flow of blood. For example, cells that felt a stronger "flow" became artery cells, while those that felt a weaker "flow" became ...

The stress and cancer link: 'Master switch' stress gene enables cancer's spread

2013-08-23
COLUMBUS, Ohio – In an unexpected finding, scientists have linked the activation of a stress gene in immune-system cells to the spread of breast cancer to other parts of the body. Researchers say the study suggests this gene, called ATF3, may be the crucial link between stress and cancer, including the major cause of cancer death – its spread, or metastasis. Previous public health studies have shown that stress is a risk factor for cancer. Researchers already know that ATF3 is activated, or expressed, in response to stressful conditions in all types of cells. Under ...

Princeton researchers use mobile phones to measure happiness

2013-08-23
Researchers at Princeton University are developing ways to use mobile phones to explore how one's environment influences one's sense of well-being. In a study involving volunteers who agreed to provide information about their feelings and locations, the researchers found that cell phones can efficiently capture information that is otherwise difficult to record, given today's on-the-go lifestyle. This is important, according to the researchers, because feelings recorded "in the moment" are likely to be more accurate than feelings jotted down after the fact. To conduct ...

Article examines fecal microbiota transplantation in the August issue of GIE®

2013-08-23
DOWNERS GROVE, Ill. – August 22, 2013 – Fecal microbiota transplantation (FMT) has emerged as a highly effective treatment for recurrent Clostridium difficile (C. difficile) infection, with very early experience suggesting that it may also play a role in treating other gastrointestinal (GI) and non-GI diseases. The topic is examined in the Review Article, "An overview of fecal microbiota transplantation: techniques, indications, and outcomes" in the August issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for ...

Scientists pinpoint a new molecular mechanism tied to pancreatic cancer

2013-08-23
New research led by scientists at The University of Texas Health Science Center at Houston (UTHealth) and Baylor College of Medicine could aid efforts to diagnose and treat one of the most lethal and hard-to-treat types of cancer. In the EMBO Molecular Medicine journal, the investigators report that they have identified a new molecular mechanism that contributes to the spread of malignant tumors in the pancreas. The hope is that drugs could one day be developed to block this pathway. Most people with pancreatic cancer die within one to two years of diagnosis and it ...

Art preserves skills despite onset of vascular dementia in 'remarkable' case of a Canadian sculptor

2013-08-23
TORONTO, Aug. 22, 2013—The ability to draw spontaneously as well as from memory may be preserved in the brains of artists long after the deleterious effects of vascular dementia have diminished their capacity to complete simple, everyday tasks, according to a new study by physicians at St. Michael's Hospital. The finding, scheduled to be released today in the Canadian Journal of Neurological Sciences, looked at the last few years of the late Mary Hecht, an internationally renowned sculptor, who was able to draw spur-of-the moment and detailed sketches of faces and figures, ...

Single injection may revolutionize melanoma treatment, Moffitt study shows

2013-08-23
A new study at Moffitt Cancer Center could offer hope to people with melanoma, the deadliest form of skin cancer. Researchers are investigating whether an injectable known as PV-10 can shrink tumors and reduce the spread of cancer. PV-10 is a solution developed from Rose Bengal, a water-soluble dye commonly used to stain damaged cells in the eye. Early clinical trials show PV-10 can boost immune response in melanoma tumors, as well as the blood stream. "Various injection therapies for melanoma have been examined over the past 40 years, but few have shown the promising ...

Brain size may signal risk of developing an eating disorder

2013-08-22
AURORA, Colo. (August 22, 2013) - New research indicates that teens with anorexia nervosa have bigger brains than teens that do not have the eating disorder. That is according to a study by researchers at the University of Colorado's School of Medicine that examined a group of adolescents with anorexia nervosa and a group without. They found that girls with anorexia nervosa had a larger insula, a part of the brain that is active when we taste food, and a larger orbitofrontal cortex, a part of the brain that tells a person when to stop eating. Guido Frank, MD, assistant ...

Lower-cost drug substitutions could mean big savings for Medicare patients, government

2013-08-22
As everyone knows, medications are expensive, and even with insurance coverage, patients' out-of-pocket drug costs can be quite hefty. This holds true for individuals with Medicare Part D, also known as the prescription drug benefit, which subsidizes the cost of medications for about 28 million Medicare beneficiaries. About one-fifth of these Part D beneficiaries have out-of-pocket costs that top $100 a month. As a result, some 10 percent are forced to use less medication than prescribed due to financial hardship. And while the program's low-income subsidy can help ...

Gladstone scientists transform non-beating human cells into heart-muscle cells

2013-08-22
VIDEO: This is a 3D image of a heart muscle cell that has been derived from a fibroblast via a process called direct reprogramming. Direct reprogramming allows one cell type to... Click here for more information. SAN FRANCISCO, CA—August 22, 2013—In the aftermath of a heart attack, cells within the region most affected shut down. They stop beating. And they become entombed in scar tissue. But now, scientists at the Gladstone Institutes have demonstrated that this damage ...

How hormones and microbes drive the gender bias in autoimmune diseases

2013-08-22
Females can mount more powerful immune responses than males, but the flip side of this enhanced protection against infections is a greater risk for autoimmune disorders. Shedding light on the underlying causes of the gender bias in autoimmune diseases, a study published by Cell Press August 22nd in the journal Immunity reveals that certain gut microbes prevalent in males can help protect them against type 1 diabetes. The study demonstrates that these microbes cooperate with sex hormones to cause this gender bias and provides an important framework that could lead to better ...

Wolves howl because they care

2013-08-22
When a member of the wolf pack leaves the group, the howling by those left behind isn't a reflection of stress but of the quality of their relationships. So say researchers based on a study of nine wolves from two packs living at Austria's Wolf Science Center that appears in Current Biology, a Cell Press publication, on August 22. The findings shed important light on the degree to which animal vocal production can be considered as voluntary, the researchers say. "Our results suggest the social relationship can explain more of the variation we see in howling behavior ...

New technique may help regenerate heart cells to treat heart disease

2013-08-22
Researchers have developed a new technique that might one day be used to convert cells from heart disease patients into heart muscle cells that could act as a personalized treatment for their condition. The research is published online on August 22 in the journal of the International Society of Stem Cell Research, Stem Cell Reports, published by Cell Press. The investigators previously reported the ability to convert scar-forming cells in the heart (called fibroblasts) into new, beating muscle in mice that had experienced heart attacks, thereby regenerating a heart from ...

Study helps explain increased melanoma risk in individuals with red hair

2013-08-22
BOSTON -- A person's skin pigment, which determines hair color and skin tone, is influenced by the melanocortin-1 (MC1R) gene receptor. For the population's one to two percent of redheads, a mutation in MC1R accounts for their red hair color and typical light skin. Now researchers from Beth Israel Deaconess Medical Center (BIDMC) and Boston University School of Medicine (BUSM) have discovered that the same MC1R mutation responsible for the red hair phenotype also promotes an important cancer-causing pathway. The new findings, reported on-line today in the journal Molecular ...

Human brains are hardwired for empathy, friendship, study shows

2013-08-22
Perhaps one of the most defining features of humanity is our capacity for empathy – the ability to put ourselves in others' shoes. A new University of Virginia study strongly suggests that we are hardwired to empathize because we closely associate people who are close to us – friends, spouses, lovers – with our very selves. "With familiarity, other people become part of ourselves," said James Coan, a psychology professor in U.Va.'s College of Arts & Sciences who used functional magnetic resonance imaging brain scans to find that people closely correlate people to whom ...

23andMe conducts the first genetic study of non-syndromic striae distensae (stretch marks)

2013-08-22
Mountain View, Calif. –August 22nd, 2013 23andMe, the leading personal genetics company, has conducted the first genetic study of striae distensae (stretch marks). Researchers at the company identified four genetic markers significantly associated with the development of stretch marks that inform why some individuals are more susceptible to the skin condition. Estimates of the prevalence of stretch marks range from 50-80 percent, however the exact causes of stretch marks are still widely unknown. Many factors, including excessive skin distension (during pregnancy, ...

Beetles modify emissions of greenhouse gases from cow pats

2013-08-22
Cattle contribute to global warming by burping and farting large amounts of greenhouse gases. Some of the same gases are also emitted from cow pats on pastures. But now researchers from the University of Helsinki have found that beetles living in cow pats may reduce emissions of the key greenhouse gas - methane. Agriculture is one of the biggest sources of the anthropogenic greenhouse gases responsible for global warming. Among these, cattle farming for meat and milk are major sources of methane, a gas with a potent warming effect. Much of this methane comes from the ...

Relating animals to humans could help conservation projects

2013-08-22
In a paper published by the journal Biodiversity Conservation, the researchers also suggest that anthropomorphism is overlooked as a powerful tool for promoting low-profile species that are either endangered or require urgent attention. At present, anthropomorphism in conservation is limited to social, intelligent animals, such as chimpanzees, polar bears and dolphins. According to the research, this would imply that other species are not worthy of conservation because they are not like humans in the 'right' ways. However, by making conservationists more aware of how ...

Old concrete can protect nature

2013-08-22
Usually we think of demolished concrete walls and floors as environmental contaminants, but in fact this material may turn out to be a valuable resource in nature protection work. This is the conclusion from researchers from University of Southern Denmark after studying the ability of crushed concrete to bind phosphorus. "We have shown that crushed concrete can bind up to 90 per cent of phosphorus, "says PhD student and environmental engineer, Melanie Sønderup, Department of Biology at the University of Southern Denmark. Contributors to the research are also postdoc, ...

A mother's genes influence her child's aging

2013-08-22
As we grow older, not only the function of organs slows down. Also on a cellular level more and more damages occur. One reason is that DNA errors accumulate which cause defective cells. Now a team of researchers lead by Nils-Göran Larsson at the Max Planck Institute for Biology of Ageing in Cologne has shown that ageing is determined not only by the accumulation of DNA damage that occurs during lifetime but also by damage that we acquire from our mothers. In a study on mice, the researchers have shown that mutations of maternally inherited mitochondrial DNA influence the ...

First laser-like X-ray light from a solid

2013-08-22
Researchers have for the first time created an X-ray laser based on a solid. The method developed at DESY's free-electron laser FLASH opens up new avenues of investigation in materials research, as reported by the team of Prof. Alexander Föhlisch of the Helmholtz Zentrum Berlin (HZB) in the British scientific journal "Nature." "This technology makes it possible to analyse sensitive samples that otherwise are quickly destroyed by intense X-ray light," notes co-author Prof. Wilfried Wurth of the University of Hamburg and the Hamburg Center for Free-Electron Laser Science ...

Engaging in a brief cultural activity can reduce implicit prejudice

2013-08-22
A small cue of social connection to someone from another group — such as a shared interest — can help reduce prejudice immediately and up to six months later, according to new research published in Psychological Science, a journal of the Association for Psychological Science. "Our research shows that even a brief opportunity to take part in another group's culture can improve intergroup attitudes even months later," says psychological scientist and lead researcher Tiffany Brannon of Stanford University. Decades of research in psychology show that extended relationships ...

2 alternative treatments may help relieve postoperative nausea

2013-08-22
San Francisco, CA. (August 22, 2013) – Two simple, non-drug treatments—aromatherapy and intravenous administration of a simple sugar solution—may offer effective new approaches to relieving nausea and vomiting after surgery, report a pair of studies in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS). "Aromatherapy is promising as an inexpensive, noninvasive treatment for postoperative nausea that can be administered and controlled by patients as needed," according to a research report by Dr Ronald ...

Study finds grandmothers who raise their grandkids struggle with depression

2013-08-22
Grandmothers who care for their grandkids fulltime need help for depression and family strains, report researchers from the Case Western Reserve University's Frances Payne Bolton School of Nursing. Carol Musil, PhD, RN, FAAN, professor of nursing, recently conducted one the longest-running studies on grandmothers in various family situations, from serving as their grandkids' fulltime caregivers to those not caring for their grandchildren as a comparison. "Although we expected the primary caregiver grandmothers raising grandchildren would have more strain and depressive ...
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