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Scientists identify gene that is consistently altered in obese individuals

Scientists identify gene that is consistently altered in obese individuals
2013-03-21
AUGUSTA, Ga. – Food and environment can chemically alter your gene function and scientists have identified a gene that is consistently altered in obesity. The gene LY86 was among a group of 100 genes identified as likely contributors to obesity through genome-wide association studies comparing the DNA of thousands of obese and lean individuals, said Dr. Shaoyong Su, genetic epidemiologist at the Medical College of Georgia at Georgia Regents University. Su looked at progressively larger groups of obese versus lean individuals and found LY86 consistently and highly chemically ...

Researchers' new method may sharpen microscopic images

2013-03-21
UT Dallas researchers are developing a new low-light imaging method that could improve a number of scientific applications, including the microscopic imaging of single molecules in cancer research. Electrical engineering professor Dr. Raimund Ober and his team recently published their findings in the journal Nature Methods. In the journal, they describe a method which minimizes the deterioration of images that can occur with conventional imaging approaches. "Any image you take of an object is translated by the camera into pixels with added electronic noise," Ober said. ...

Do I know you? Memory patterns help us recall the social webs we weave, finds new Cornell study

2013-03-21
ITHACA, N.Y. — With a dizzying number of ties in our social networks – that your Aunt Alice is a neighbor of Muhammad who is married to Natasha who is your wife's boss – it's a wonder we remember any of it. How do we keep track of the complexity? We cheat, says a Cornell University sociologist in Scientific Reports (March 21), a publication of Nature. Study: http://www.nature.com/srep/2013/130321/srep01513/full/srep01513.html Humans keep track of social information not by rote memorization but with simplifying rules, as you might remember a number sequence that always ...

Genetic risk strategies needed for young, black, female breast cancer patients, Moffitt study shows

2013-03-21
Researchers at Moffitt Cancer Center and colleagues in Canada have published study results focused on black women younger than 50, a population disproportionately afflicted with and dying from early-onset breast cancer compared to their white counterparts. The research published in the Jan. 16 issue of The Breast Journal. Early-onset breast cancer has been associated with mutations in the BRCA1 and BRCA2 genes. These breast cancer predisposing genes were discovered almost 20 years ago and confer a lifetime risk of breast cancer of 60 to 70 percent, as well as a much higher ...

Berkeley Lab scientists read the cosmic writing on the wall

Berkeley Lab scientists read the cosmic writing on the wall
2013-03-21
Thanks to a supersensitive space telescope and some sophisticated supercomputing, scientists from the international Planck collaboration have made the closest reading yet of the most ancient story in our universe: the cosmic microwave background (CMB). Today, the team released preliminary results based on the Planck observatory's first 15 months of data. Using supercomputers at the U.S. Department of Energy's (DOE) National Energy Research Scientific Computing Center (NERSC) Planck scientists have created the most detailed and accurate maps yet of the relic radiation ...

For the first time, recommendations offer guidance about incidental genetic findings

2013-03-21
Boston – In a highly anticipated report, landmark recommendations on the handling of incidental findings in clinical genome and exome sequencing are being issued from the American College of Medical Genetics and Genomics (ACMG). A report of the recommendations, led by Robert C. Green, MD, MPH, a medical geneticist at Brigham and Women's Hospital (BWH), outlines for the first time a minimum list of genetic conditions, genes and variants that laboratories performing clinical sequencing should seek and report to the physicians that ordered the testing -- regardless of the ...

European Guidance for the diagnosis & management of osteoporosis in postmenopausal women

2013-03-21
A new Guidance recently published by the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the International Osteoporosis Foundation (IOF) reflects the most current advances in the diagnosis and management of osteoporosis, the 'silent disease' which affects up to one in two postmenopausal women. "The serious impact of fragility fractures due to osteoporosis is vastly underestimated by many health care professionals," stated ESCEO President Professor Jean-Yves Reginster. "Statistics clearly show that fragility fractures in older adults ...

Differences in bone healing in old mice may hold answers to better bone healing for seniors

2013-03-21
Philadelphia – By studying the underlying differences in gene expression during healing after a bone break in young versus aged mice, Jaimo Ahn, MD, PhD, assistant professor of Orthopaedic Surgery at the Perelman School of Medicine, University of Pennsylvania, and his colleagues aim to find specific pathways of fracture healing in humans. The team of researchers will present their findings in a poster presentation beginning Tuesday, March 19, 2013 at the 2013 American Academy of Orthopedic Surgeons annual meeting in Chicago. Problems with healing after bone fractures ...

Microalgae could be a profitable source of biodiesel

2013-03-21
Researchers at the UAB's Institute of Environmental Science and Technology (ICTA-UAB) and the Institute of Marine Sciences (ICM-CSIC), have analysed the potential of different species of microalgae for producing biodiesel, comparing their growth, production of biomass and the quantity of lipids per cell (essential for obtaining fuel). Their study shows that one type of marine algae that has received little attention till now - dinoflagellate microalgae - is highly suitable for cultivation with the aim of producing biodiesel. The scientists carried out the whole production ...

Findings to help in design of drugs against virus causing childhood illnesses

2013-03-21
WEST LAFAYETTE, Ind. - New research findings may help scientists design drugs to treat a virus infection that causes potentially fatal brain swelling and paralysis in children. The virus, called enterovirus 71, causes hand, foot and mouth disease and is common throughout the world. Although that disease usually is not fatal, the virus has been reported to cause fatal encephalitis in infants and young children, primarily in the Asia-Pacific region. Currently, no cure exists for the infection. New findings show the precise structure of the virus bound to a molecule that ...

Understanding the continuous corn yield penalty

2013-03-21
URBANA – As escalating corn prices have encouraged many farmers to switch to growing corn continuously, they wonder why they have been seeing unusually high yield reductions over the past several years. The University of Illinois conducted a six-year study that identified three key factors affecting yield in continuous corn (CC) systems. "Prior to this study, the most common management recommendations for continuous corn production were to apply an additional 45 pounds of nitrogen per acre and reserve your best crop land for it," said U of I soil scientist and lead author ...

Park amenities differ according to income of neighborhoods

Park amenities differ according to income of neighborhoods
2013-03-21
COLUMBIA, Mo. – Every community in America has its share of parks. However, park amenities in certain communities can be lacking, which can be detrimental to the health of potential patrons. Now, a University of Missouri researcher has found that while more parks exist in lower-income neighborhoods, they tend to be less attractive than parks in upper- and middle-class neighborhoods, which have more amenities and are more visually pleasing. "Parks are important for physical activity and socialization among community members," said Sonja Wilhelm Stanis, assistant professor ...

Planck's new map brings universe into focus

2013-03-21
The Planck space mission has today (March 21) released the most accurate and detailed map ever made of the oldest light in the universe. The universe according to Planck is expanding a bit more slowly than thought, and at 13.8 billion is 100 million years older than previously estimated. There is a bit less dark energy and a bit more of both normal and dark matter in the universe — although the nature of dark energy and dark matter remain mysterious. "Planck's high-precision map of the oldest light in our universe allows us to extract the most refined values yet of the ...

Physical therapy as effective as surgery for torn meniscus and arthritis of the knee

2013-03-21
Alexandria, VA, March 21, 2013 — A New England Journal of Medicine (NEJM) study showing that physical therapy is just as effective as surgery in patients with meniscal tears and arthritis of the knee should encourage many health care providers to reconsider their practices in the management of this common injury, according to the American Physical Therapy Association (APTA). The study, published March 19, showed no significant differences in functional improvement after 6 months between patients who underwent surgery with postoperative physical therapy and those who received ...

Archerfish get an eye test

2013-03-21
Dr Shelby Temple, now at the University of Bristol, and his team at the University of Queensland and the University of Western Australia used a modified version of the Landolt C test to discover just how fine a detail the archerfish could resolve. The researchers first trained the fish to spit at one of two letters – an 'O' or a 'C' – by rewarding them with food. Then they showed them small versions of both letters together and recorded which letter they spat at. Dr Temple said: "This modified Landolt C test works because the only difference between the two letters ...

Quantum computers counting on carbon nanotubes

Quantum computers counting on carbon nanotubes
2013-03-21
Using quantum mechanical phenomena, computers could be much more powerful than their classical digital predecessors. Scientists all over the world are working to explore the basis for quantum computing. To date most systems are based on electrically charged particles that are held in an "electromagnetic trap." A disadvantage of these systems is that they are very sensitive to electromagnetic interference and therefore need extensive shielding. Physicists at the Technische Universitaet Muenchen have now found a way for information to be stored and quantum mechanically processed ...

Discovery could increase efficacy of promising cystic fibrosis drug

Discovery could increase efficacy of promising cystic fibrosis drug
2013-03-21
A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future. Described in the current issue of the Proceedings of the National Academy of Sciences, MU researchers have redefined a key regulatory process in the defective protein responsible for cystic fibrosis that could change the way scientists approach the lethal genetic disease. "They know the drug ...

The Seven Star Global Luxury Awards has Confirmed their Final Travel, Tourism and Hospitality Nominees; With Voting Now Open to the Public and Trade...

The Seven Star Global Luxury Awards has Confirmed their Final Travel, Tourism and Hospitality Nominees; With Voting Now Open to the Public and Trade...
2013-03-21
The Seven Star Global Luxury Awards continues to gain momentum with online voting already exceeding expectations after only a few weeks. With the most sought-after brands in the travel, tourism and hospitality industries vying to be honored with the Signum Virtutis - the seal of excellence, being bestowed upon them for 2013; competition is becoming fierce on a global scale. The results will be revealed at the Awards Ceremony; honoring this elite collection of nominees with this highest and most exclusive award for being the pinnacle of luxury and lifestyle in these ...

Warm springs may be best winter refuge for Florida manatees

Warm springs may be best winter refuge for Florida manatees
2013-03-21
During the winter, manatees in Florida rely on warm-water refuges in the southern peninsula, and consistently return to one more specific areas. This new study assessed the proportion of manatees that use natural springs, power plant discharge areas, and passive 'thermal basins' that trap warm water for a week or more. They found that nearly half of all animals they counted sought out power plant outfalls for warmth, while approximately 17% chose warm springs. In the coldest periods the proportion at power plants can increase to two-thirds. Despite this relatively small ...

3-year olds know rules of sharing but don't follow them until older

2013-03-21
The authors note, "People who spend time with young children will know that they often favor themselves when sharing, but surprisingly they endorse equal sharing not just by other people but also in their own case. In our research, we were able to rule out a number of explanations for this early gap between word and deed." When the researchers gave 3-8-year-olds stickers they valued and asked them about sharing, children of all ages readily asserted that they themselves should share equally, and others should as well. However, when given the chance to actually share, ...

Fear factor increases, emotions decrease in books written in last 50 years

2013-03-21
The authors analyzed trends in the use of 'mood words' that convey joy, anger, fear and other emotions and found a general, overall decrease in the use of words that convey emotions. They found distinct historical periods of positive and negative moods in books that correlated with socio-political events like World War II, the Great Depression or the Baby Boom. In contrast to the five other moods studied, words that convey fear showed an opposite trend. Words conveying fear declined in use through the early 20th century but increased markedly since the 1970s, despite ...

Roman mausoleum tested for ancient earthquake damage

2013-03-21
Please cite the Bulletin of the Seismological Society of America (BSSA) as the source of this information. Built under a sheer cliff, with a commanding view of the forum and castle in the ancient city of Pinara in Turkey, a Roman mausoleum has been knocked off-kilter, its massive building blocks shifted and part of its pediment collapsed. The likely cause is an earthquake, according to a new detailed model by Klaus-G. Hinzen and colleagues at the University of Cologne. They conclude that a 6.3 magnitude earthquake could have caused the damage, and their new finding gives ...

Can intraplate earthquakes produce stronger shaking than at plate boundaries?

2013-03-21
Please cite the Bulletin of the Seismological Society of America (BSSA) as the source of this information. New information about the extent of the 1872 Owens Valley earthquake rupture, which occurs in an area with many small and discontinuous faults, may support a hypothesis proposed by other workers that these types of quakes could produce stronger ground shaking than plate boundary earthquakes underlain by oceanic crust, like many of those taking place along the San Andreas fault. Published estimates of the 1872 Owens Valley earthquake in southeastern California put ...

Maternal diabetes impairs methylation of imprinted gene in oocytes

2013-03-21
For the first time, researchers have shown that poorly controlled maternal diabetes has an adverse effect on methylation of the maternal imprinting gene Peg3, contributing to impaired development in offspring. Previous studies have revealed that offspring of diabetic mothers display a higher incidence of malformations and fetal death, even when a one-cell embryo is transplanted from a diabetic to a non-diabetic mother. Diabetic mothers' oocytes tend to exhibit reduced glucose metabolism, compromised communication between cumulus cells and oocytes, mitochondrial malfunction, ...

Researchers link Gulf War Illness to physical changes in brain fibers that process pain

2013-03-21
WASHINGTON — Researchers at Georgetown University Medical Center (GUMC) have found what they say is evidence that veterans who suffer from "Gulf War Illness" have physical changes in their brains not seen in unaffected individuals. Brain scans of 31 veterans with the illness, compared to 20 control subjects, revealed anomalies in the bundles of nerve fibers that connect brain areas involved in the processing and perception of pain and fatigue. The discovery, published online March 20 in PLOS ONE, could provide insight into the mysterious medical symptoms reported by more ...
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