Raghu R. Chivukula, MD, PhD, a physician-investigator in the Departments of Medicine & Surgery and the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School, is the senior author of a paper published in Science, “Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders.”   Q: How would you summarize your study for a lay audience? Neurodegenerative disorders, such as Alzheimer’s disease and Parkinson’s disease, are devastating and incurable diseases. Although many neurodegenerative ...

Quicker health diagnoses, smarter energy supplies, tackling climate change and improved public service delivery – just some huge potential benefits of the new compute roadmap, launched by DSIT and UKRI. The roadmap heralds a significant increase in publicly accessible compute capacity. Investments include up to £2 billion to deliver a holistic and user-centred compute ecosystem with  £1 billion to expand the AI Research Resource 20-fold by 2030. It also provides up to £750 million for UKRI to invest in a new national supercomputing service at Edinburgh. UKRI is further ...

South San Francisco, CA (July 17, 2025) - A new study sponsored by Mirvie, which is the first to evaluate U.S. Preventive Services Task Force (USPSTF) guidelines for preeclampsia risk and aspirin prescription in a single, nationally representative, prospective population, found while high-risk factors had sufficient value in estimating risk, there’s limited value for the moderate risk category - leading to nonspecific recommendations for aspirin use, a recognized prevention tool.    This cohort study of 5684 participants, culled from the multi-center Miracle of Life prospective study, found the guidelines ...

A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer. The study, published in JAMA Network Open in collaboration with researchers at Mayo Clinic in Arizona, found that the absence of detectable tumors after treatment – a key metric in clinical cancer drug trials known as pathologic complete response or pCR – does not reliably predict an improvement in long-term survival for patients diagnosed with ...

Q: How would you summarize your study for a lay audience? Dr. McElrath: Preeclampsia (PE) is a hypertensive disease that complicates 7-10% of pregnancies. While recent advances in understanding the underlying causes of PE have been made, predicting its occurrence has historically been difficult because it is a complex condition that likely results from a variety of causes and can present in different ways. To address this challenge, the United States Preventive Services Task Force (USPSTF) reviewed ...

CORVALLIS, Ore. – Oregon State University pigment researchers are using a rare mineral discovered in Norway more than a century ago as a road map for creating new yellows, oranges and reds that are vibrant, durable, non-toxic and inexpensive. The new pigments also carry energy-saving potential: Their ability to reflect heat from the sun means that buildings and vehicles coated in them will require less air conditioning. The study led by Mas Subramanian, who made color history in 2009 with the discovery of a vivid blue pigment now known commercially as YInMn Blue, was published in Chemistry of Materials. Funded by the National Science Foundation, ...

Increased transparency from countries about how they use AI to manage migration is needed to boost trust and strengthen the rule of law, a new study says. Any overuse of AI in migration management may perpetuate biases and errors, promoting excessive reliance on technology and undermining trust in decision‑making processes, an expert has warned. Adequate cybersecurity measures are also needed to protect sensitive data about vulnerable migrants. However, using AI for migrant management could present opportunities such as freeing up caseworkers’ time to focus on other critical areas, ...

Centuries ago, alchemists worked furiously to convert the common metal lead to valuable gold. Today, chemists are repurposing discarded solar panels to create valuable organic compounds from carbon dioxide (CO2), a common greenhouse gas. Significantly reducing greenhouse gasses in the atmosphere to mitigate the most devastating effects of climate change will require a large reduction in emissions as well as strategies designed to sequester emitted CO2 and other offending gasses. While simply sequestering ...

Several local factors — including the minimum temperature reached in autumn, the water level in lakes and ponds in winter, and the presence of mute swans (Cygnus olor) — could be key for predicting the potential of an outbreak of highly pathogenic avian flu (HPAI) occurring in Europe. The findings, published in Scientific Reports, are derived from a machine learning model trained on the characteristics of 21st century European HPAI outbreaks and could help improve future monitoring programmes. HPAI outbreaks are a serious concern for both animal and public health. A wave of HPAI outbreaks across the Northern Hemisphere during 2022 were associated with an ...

Boston, MA – July 17, 2025 – Early-onset gastrointestinal (GI) cancers are rising at alarming rates worldwide and, in the U.S., are increasing faster than any other type of early-onset cancer, including breast cancer, according to two recent literature reviews from Dana-Farber Cancer Institute. "Early-Onset Gastrointestinal Cancers: A Review," published today in JAMA, provides a comprehensive analysis of the incidence, risk factors, and treatment approaches for early-onset GI cancers. Authors note the rising rate goes ...

Vaccine boosters help keep cancer patients from being hospitalized or admitted to intensive care units due to COVID-19, according to a new study led by Cedars-Sinai investigators. Their findings, published in JAMA Oncology, offer real-world evidence to support vaccine recommendations for these patients. “Cancer patients are a vulnerable population,” said Jane Figueiredo, PhD, director of Community Health and Population Research at Cedars-Sinai and senior author of the study. “Their immune systems can be weakened by their disease and the treatments they receive, ...

About The Study: In this retrospective cohort study, COVID-19 booster vaccinations were associated with significant protection against severe COVID-19, with a favorable number needed to vaccinate among persons with cancer. However, uptake of COVID-19 vaccine boosters was low, and interventions are therefore justified to increase COVID-19 vaccine uptake in this high-risk population. Corresponding Author: To contact the corresponding author, Jacek Skarbinski, MD, email jacek.skarbinski@kp.org. To access the ...

About The Study: The results of this study suggest an association between cannabis use disorder and benign salivary gland tumors. Future prospective research with large samples and data on cannabis dosing, method of use, and benign salivary gland neoplasm pathology is required to further assess and confirm this association. Corresponding Author: To contact the corresponding author, Niels C. Kokot, MD, email niels.kokot@med.usc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoto.2025.1955) Editor’s ...

About The Study: In line with prior research, the results of this study indicate that the public has certain reservations about the integration of artificial intelligence (AI) in health care. While the present effect sizes are relatively small, in particular regarding AI use for administrative purposes, they may be highly relevant as trust in health care practitioners is closely linked to subjective treatment outcomes.  Corresponding Author: To contact the corresponding author, Moritz Reis, MSc, email moritz.reis@uni-wuerzburg.de. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.21643) Editor’s ...

The way household dogs engage with TV may depend on their personalities, suggests research published in Scientific Reports. Excitable dogs were more likely to follow on-screen objects while fearful or anxious dogs were more likely to respond to stimuli such as cars or a doorbell, with the dogs surveyed watching TV for an average of 14 minutes and eight seconds.  There has been an increase in dog-specific television programming in recent years and the frequency with which dogs are exposed to different forms of media is increasing. However, to date there has been no systematic assessment of the way in which pet dogs engage with TV at the population-level. Lane Montgomery and colleagues ...

ITHACA, N.Y. — Why is it so hard to stick to New Year’s resolutions all year long? A new study from Cornell University has found an answer: The key to achieving goals is less about the outcome and more about enjoying the journey. The findings, published July 15 in Psychological Science, challenge the assumption that if a goal is important or valuable, we’ll naturally be more likely to stick with it. Instead, they show people are more likely to stay committed to resolutions that are fun, engaging, and personally rewarding. “Across ...

Recently, Nano Research announced awardees of the 2024 Nano Research Young Innovators (NR45) Awards in Nanomaterial Self-assembly. Twenty-four outstanding young investigators under the age of 45 were selected for their extraordinary contributions in nanomaterial self-assembly. They were selected through a competitive process by an award committee from Nano Research’s editorial board. Congratulations to all the 24 awardees in 2024!   The 24 awardees include Dr. Jiarong Cai from Nankai University; Dr. Jie Chao from Nanjing University of Post & Telecommunications; ...

Integrated carbon capture and utilization has become a promising technology to achieve carbon neutrality. However, conventional studies focused on the development of novel dual-functional materials while neglecting the impact of common impurities such as sulfur oxides (SOx) and nitrogen oxides (NOx), thereby limiting the practical industrial applicability of ICCU technology. A team of scientists has investigated the impact of SO2 and NO2 on the ICCU-dry reforming of methane (ICCU-DRM) process using a representative Ni-Ca dual-functional material. Their work is published in the journal Industrial Chemistry & Materials on 04 July 2025. “We ...

The University of Virginia School of Medicine’s Harald Sontheimer, PhD, and Stanford’s Michelle Monje, MD, PhD, have received the 2025 International Prize in Translational Neuroscience from the Gertrud Reemtsma Foundation for their pioneering research in the emerging field of cancer neuroscience. In announcing this year’s recipients, the foundation noted that Sontheimer and Monie’s work has “fundamentally changed our understanding of brain tumors” and opened ...

Background and objectives Soft tissue cytopathology plays a vital role in the diagnosis and management of soft tissue neoplasms, necessitating a standardized classification system to improve diagnostic accuracy and guide clinical decision-making. This article provides a concise review of the World Health Organization (WHO) Reporting System for Soft Tissue Cytopathology and presents a practical diagnostic approach to soft tissue cytopathology. Methods The WHO Reporting System is reviewed in conjunction with relevant literature. The reporting system employs a six-category framework: non-diagnostic, benign, atypical, soft tissue neoplasm of uncertain malignant potential, suspicious ...

“Non-sarcopenic, community-dwelling middle-aged and older adults could be validly classified in terms of their individual musculoskeletal ageing trajectories with a novel muscular clock, MAA.” BUFFALO, NY — July 17, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 9, 2025, titled “Developing a quantitative estimate of muscle age acceleration by a novel phenotypic clock: cross-sectional study in healthy, middle-aged and older adults.” In this study, led by first authors Lucia Ventura, Antonella Cano and Marco Morrone, along with corresponding ...

Learning to swim is important, especially in a country like Norway, where many people live near the coast, a river, or a lake. For this reason, swimming instruction is included in the physical education curriculum in primary and lower secondary schools. But does the swimming instruction children in Norway receive actually help when the knowledge and skills are needed the most? “In Norway, swimming instruction mainly takes place in stable, controlled and predictable environments, such as heated swimming pools,” explained Jon Sundan, from the ...

The artificial intelligence revolution hasn’t passed older adults by, a new poll suggests. But the data show that people over 50 have both curiosity and skepticism about AI, depending on how much they’ve used it, the data show.   No matter what their level of experience with AI, nearly all people over 50 (92%) say they want to know when the information they read, see or hear is AI-generated, according to the new findings from the University of Michigan National Poll on Healthy Aging.  In all, just over half (55%) of people age 50 and older have ever used an AI technology ...

Generative artificial intelligence (AI) has the potential to revolutionize fashion design. By recognizing patterns in data and generating new text and images, AI models powered by deep learning algorithms can help fashion designers develop new catalogues, expanding their creativity, with added efficiency, helping to bring products to the market faster. Large language models (LLMs) like ChatGPT and AI image generators like DALL-E have already shown promising results for many industries and have popularized the use of AI. In fashion, LLMs can help designers and even non-experts understand past styles and predict future ...

Microbial contaminants like airborne bacteria and fungi can make up more than a third of indoor air pollution. Yet, while many countries regulate chemical pollutants, most have no legally binding thresholds for microbial exposure, particularly fungi. This lack of toxicological benchmarks leaves a major gap in indoor air safety policy. Addressing this gap, a new study led by Professor Wonsuck Yoon of Korea University provides the first species-specific health risk estimates for indoor airborne microbes based on animal toxicity data. This study was made available online on June 9, 2025, and was published on Sep 5, 2025, ...