Opposites attract: How cells and cell fragments move in electric fields
2013-03-28
VIDEO:
These fish cells crawl towards the negative electrode, or cathode, and change direction when the electric field is reversed. Electric fields may recruit or guide cells into wounded tissue.
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Like tiny crawling compass needles, whole living cells and cell fragments orient and move in response to electric fields — but in opposite directions, scientists at the University of California, Davis, have found. Their results, published April 8 in ...
UMMS scientists tie dietary influences to changes in gene expression and physiology
2013-03-28
WORCESTER, MA – Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts Medical School (UMMS) raises the striking possibility that even small amounts of these occasional indulgences may produce significant changes in gene expression that could negatively impact physiology and health.
A pair of papers published in Cell by A.J. Marian Walhout, PhD, co-director of the Program in Systems Biology and professor ...
Hubble observes the hidden depths of Messier 77
2013-03-28
Messier 77 is a galaxy in the constellation of Cetus, some 45 million light-years away from us. Also known as NGC 1068, it is one of the most famous and well-studied galaxies. It is a real star among galaxies, with more papers written about it than many other galaxies put together!
Despite its current fame and striking swirling appearance, the galaxy has been a victim of mistaken identity a couple of times; when it was initially discovered in 1780, the distinction between gas clouds and galaxies was not known, causing finder Pierre Mechain to miss its true nature and ...
Study reveals how diabetes drug delays ageing in worms
2013-03-28
A widely prescribed type 2 diabetes drug slows down the ageing process by mimicking the effects of dieting, according to a study published today using worms to investigate how the drug works.
Following a calorie-restricted diet has been shown to improve health in later life and extend lifespan in a number of animals, ranging from the simple worm to rhesus monkeys. The type 2 diabetes drug metformin has been found to have similar effects in animals but until now it was not clear exactly how the drug delays the ageing process.
Researchers supported by the Wellcome Trust ...
What attracts people to violent movies?
2013-03-28
Washington, DC (March 26, 2013) – Why are audiences attracted to bloodshed, gore and violence? A recent study from researchers at the University of Augsburg, Germany and the University of Wisconsin-Madison found that people are more likely to watch movies with gory scenes of violence if they felt there was meaning in confronting violent aspects of real life.
Anne Bartsch, University of Augsburg, Germany and Louise Mares, University of Wisconsin-Madison, will present their findings at the 63rd Annual Conference of the International Communication Association. Their study ...
A social network for young Londoners on the buses
2013-03-28
Free bus travel has improved the social lives and independence of 12-18 year olds in London, according to research published today in the journal Mobilities.
Researchers from the London School of Hygiene & Tropical Medicine and UCL (University College London) found that free bus travel – which all young Londoners are entitled to by registering for a Zip Oyster Card – increased young people's ability to travel independently and extended their opportunities through facilitating extra trips, trips further afield and/or exploratory trips with friends.
Travelling together ...
Should I trust my intuition?
2013-03-28
A study led by Zachary Mainen, Director of the Champalimaud Neuroscience Programme, and published today (March 28th) in the scientific journal, Neuron, reports that when rats were challenged with a series of perceptual decision problems, their performance was just as good when they decided rapidly as when they took a much longer time to respond. Despite being encouraged to slow down and try harder, the subjects of this study achieved their maximum performance in less than 300 milliseconds.
'There are many kinds of decisions, and for some, having more time appears to be ...
Protective prion keeps yeast cells from going it alone
2013-03-28
CAMBRIDGE, Mass. (March 28, 2013) – Most commonly associated with such maladies as "mad cow disease" and Creutzfeldt-Jakob disease, prions are increasingly recognized for their ability to induce potentially beneficial traits in a variety of organisms, yeast chief among them.
Now a team of scientists has added markedly to the job description of prions as agents of change, identifying a prion capable of triggering a transition in yeast from its conventional single-celled form to a cooperative, multicellular structure. This change, which appears to improve yeast's chances ...
Scientists propose revolutionary laser system to produce the next LHC
2013-03-28
An international team of physicists has proposed a revolutionary laser system, inspired by the telecommunications technology, to produce the next generation of particle accelerators, such as the Large Hadron Collider (LHC).
The International Coherent Amplification Network (ICAN) sets out a new laser system composed of massive arrays of thousands of fibre lasers, for both fundamental research at laboratories such as CERN and more applied tasks such as proton therapy and nuclear transmutation.
The results of this study are published today in Nature Photonics.
Lasers ...
Scientists identify brain's 'molecular memory switch'
2013-03-28
Scientists have identified a key molecule responsible for triggering the chemical processes in our brain linked to our formation of memories. The findings, published in the journal Frontiers in Neural Circuits, reveal a new target for therapeutic interventions to reverse the devastating effects of memory loss.
The BBSRC-funded research, led by scientists at the University of Bristol, aimed to better understand the mechanisms that enable us to form memories by studying the molecular changes in the hippocampus — the part of the brain involved in learning.
Previous ...
Declaring a truce with our microbiological frienemies
2013-03-28
Managing bacteria and other microorganisms in the body, rather than just fighting them, may be lead to better health and a stronger immune system, according to a Penn State biologist.
Researchers have historically focused on microbes in the body as primarily pathogens that must be fought, said Eric Harvill, professor of microbiology and infectious disease. However, he said that recent evidence of the complex interaction of the body with microbes suggests a new interpretation of the relationship.
"Now we are beginning to understand that the immune system interacts with ...
Parkinson's disease protein gums up garbage disposal system in cells
2013-03-28
PHILADELPHIA – Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.
"No one has been able to determine if Lewy bodies and Lewy neurites, hallmark pathologies in Parkinson's disease can be degraded," says Virginia Lee, PhD, director of the Center for Neurodegenerative Disease Research, at the Perelman School of Medicine, University of Pennsylvania.
"With the new neuron model system of Parkinson's disease pathologies our lab has developed recently, we demonstrated that these aberrant clumps ...
Common -- but without a name
2013-03-28
The most commonly occurring red alga in the algal order Bangiales in New Zealand has at last received a formal scientific name. Pyropia plicata, is an intertidal red alga, found in abundance in the North, South and Chatham Islands. It has been confused for many years with a species first collected from the New Zealand subantarctic islands in 1840. Recent research had clarified the identity and distribution of the southern species, Porphyra columbina, and also transferred it to the genus Pyropia. The description of Py. plicata was published in the open access journal PhytoKeys.
The ...
Mayo Clinic study: Physician spouses very satisfied in relationships
2013-03-28
ROCHESTER, Minn. -- It appears that the majority of spouses/partners of physicians in the United States are happy with their relationships, according to Mayo Clinic research. Of the about 900 spouses/partners of physicians who responded to a national survey, 85 percent said that they were satisfied in their relationship and 80 percent said they would choose a physician spouse/partner again if they could revisit their choice. These values are similar to those of married adults in the U.S. overall. The study appears in the March edition of Mayo Clinic Proceedings.
Consistent ...
Proximity to coal-tar-sealed pavement raises risk of cancer, study finds
2013-03-28
WACO, Texas (March 28, 2013)- People living near asphalt pavement sealed with coal tar have an elevated risk of cancer, according to a study in the journal Environmental Science and Technology. Much of this calculated excess risk results from exposures in children, age six or younger, to polycyclic aromatic hydrocarbons (PAHs) from the sealant.
"The increased cancer risk associated with coal-tar-sealed asphalt (CSA) likely affects a large number of people in the U.S. Our results indicate that the presence of coal-tar-based pavement sealants is associated with significant ...
Common gene variants explain 42 percent of antidepressant response
2013-03-28
Philadelphia, PA, March 28, 2013 – Antidepressants are commonly prescribed for the treatment of depression, but many individuals do not experience symptom relief from treatment. The National Institute of Mental Health's STAR*D study, the largest and longest study ever conducted to evaluate depression treatment, found that only approximately one-third of patients responded within their initial medication trial and approximately one-third of patients did not have an adequate clinical response after being treated with several different medications. Thus, identifying predictors ...
Wilderness therapy programs less risky than daily life, UNH research finds
2013-03-28
DURHAM, N.H. – Adolescents participating in wilderness and adventure therapy programs are at significantly less risk of injury than those playing football and are three times less likely to visit the emergency room for an injury than if they were at home, a new study by University of New Hampshire researchers finds. These findings, based on an analysis of risk management data from 12 programs providing outdoor behavioral healthcare in 2011, were reported in the latest issue of the Journal of Therapeutic Schools and Programs.
"After 'does this program work?', the question ...
Brain scans might predict future criminal behavior
2013-03-28
ALBUQUERQUE, NM and DURHAM, NC--A new study conducted by The Mind Research Network in Albuquerque, N.M., shows that neuroimaging data can predict the likelihood of whether a criminal will reoffend following release from prison.
The paper, which is to be published in the Proceedings of the National Academy of Sciences, studied impulsive and antisocial behavior and centered on the anterior cingulate cortex (ACC), a portion of the brain that deals with regulating behavior and impulsivity.
You can view the paper by clicking here: http://www.pnas.org/cgi/doi/10.1073/pnas.1219302110.
The ...
Cell reprogramming during liver regeneration
2013-03-28
PHILADELPHIA — During embryonic development, animals generate many different types of cells, each with a distinct function and identity.
"Although the identities of these cells remain stable under normal conditions, some cells can be persuaded to take on new identities, through reprogramming," says Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania.
Researchers have been able to reprogram cells experimentally, but few have shown that cells can change their identities ...
Theory and practice key to optimized broadband, low-loss optical metamaterials
2013-03-28
The union of theory and practice makes broadband, low-loss optical devices practical, which is why two groups of Penn State engineers collaborated to design optical metamaterials that have custom applications that are easily manufactured.
Metamaterials are manufactured materials that derive their unusual properties from structure rather than only composition, and possess exotic properties not usually found in nature. Nanostructured metamaterials appear different for signals of different frequencies. They are dispersive, so that if researchers manipulate this material ...
Surgical menopause may prime brain for stroke, Alzheimer's
2013-03-28
Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.
"This is what the clinical studies indicate and our animal studies looking at the underlying mechanisms back this up," said Brann, corresponding author of the study in the journal Brain. "We wanted to find out why that is occurring. We suspect it's due to the premature loss of estrogen."
In an effort to mimic what occurs in women, Brann and his colleagues looked at rats 10 weeks after removal of their estrogen-producing ovaries that were ...
Swarming robots could be the servants of the future
2013-03-28
Swarms of robots acting together to carry out jobs could provide new opportunities for humans to harness the power of machines.
Researchers in the Sheffield Centre for Robotics, jointly established by the University of Sheffield and Sheffield Hallam University, have been working to program a group of 40 robots, and say the ability to control robot swarms could prove hugely beneficial in a range of contexts, from military to medical.
The researchers have demonstrated that the swarm can carry out simple fetching and carrying tasks, by grouping around an object and working ...
New research on the effects of traumatic brain injury
2013-03-28
Considerable opportunity exists to improve interventions and outcomes of traumatic brain injury (TBI) in older adults, according to three studies published in the recent online issue of NeuroRehabilitation by researchers from the Icahn School of Medicine at Mount Sinai.
An Exploration of Clinical Dementia Phenotypes Among Individuals With and Without Traumatic Brain Injury
Some evidence suggests that a history of TBI is associated with an increased risk of dementia later in life, but the clinical features of dementia associated with TBI have not been well investigated. ...
Creating inclusive child-care spaces
2013-03-28
(Edmonton) Researchers from the University of Alberta are teaming up with child-care providers and day-home operators to ensure they have adequate training and support needed to offer inclusive spaces for children with disabilities.
Lesley Wiart was the lead author of a new study that identified challenges in providing inclusive spaces for children with physical disabilities, cognitive impairments and behavioural issues. The research showed that many Alberta child-care centres and day homes support inclusion but sometimes lack training and support.
"Even though providers ...
Mate choice in mice is heavily influenced by paternal cues
2013-03-28
This press release is available in German.
Mate choice is a key factor in the evolution of new animal species. The choice of a specific mate can decisively influence the evolutionary development of a species. In mice, the attractiveness of a potential mate is conveyed by scent cues and ultrasonic vocalizations. Researchers from the Max Planck Institute for Evolutionary Biology in Plön investigated whether house mice (Mus musculus) would mate with each other even if they were from two populations which had been separated from each other for a long time period. To do this, ...
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