Cambridge, MA, February xx, 2013 – Eleven Biotherapeutics, a biopharmaceutical company creating novel and differentiated protein-based biotherapeutics, has published preclinical data in Proceedings of the National Academy of Sciences (PNAS) showing beneficial effects of EBI-005, the first rationally-designed topically administered IL-1 protein for the treatment of ocular diseases. In the paper entitled "Design of a superior cytokine antagonist for topical ophthalmic use," the scientists, including drug developers from Eleven Biotherapeutics and collaborators from Howard ...

Hepatitis C virus (HCV) infection affects about 4.1 million in the United States and is the primary cause of liver cirrhosis and liver cancer. Current therapy against HCV is suboptimal. Daclatasvir, a direct acting antiviral (DAA) agent in development for the treatment of HCV, targets one of the HCV proteins (i.e., NS5A) and causes the fastest viral decline (within 12 hours of treatment) ever seen with anti-HCV drugs. An interdisciplinary effort by mathematical modelers, clinicians and molecular virologists has revealed that daclatasvir has two main modes of action against ...

SALT LAKE CITY, Feb. 19, 2013 – University of Utah researchers ran computer simulations to show that the snow-producing "lake effect" isn't always enough to cause heavy snowfall, but that mountains or other surrounding topography sometimes are necessary too. The study is relevant not only to forecasting lake-effect storms near the Great Salt Lake, Sea of Japan, Black Sea and other mountainous regions, but also sheds light on how even gentle topography near the Great Lakes helps enhance lake-effect snowstorms, says the study's senior author, Jim Steenburgh, a professor ...

OAK BROOK, Ill. – Coronary computed tomography angiography (CCTA) is an effective tool for determining the risk of heart attacks and other adverse cardiac events in patients with suspected coronary artery disease but no treatable risk factors, such as high cholesterol or high blood pressure, according to a new study published online in the journal Radiology. "CCTA should be considered as an appropriate first- line test for patients with atypical chest pain and suspected but not confirmed coronary artery disease," said the study's lead author, Jonathon Leipsic, M.D., ...

Researchers have determined that fibromyalgia prevalence is 2.1% of the general population in Germany. Results appearing in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR), suggest that fibromyalgia is a spectrum disorder rather than a categorical illness. Additionally, a number of fibromyalgia cases in the general population satisfy proposed criteria for physical symptom disorder—the presence of one or more physical symptoms that impair function, which cannot be explained by another clinical or psychiatric ...

The new coronavirus that has emerged in the Middle East is well-adapted to infecting humans but could potentially be treated with immunotherapy, according to a study to be published on February 19 in mBio®, the online open-access journal of the American Society for Microbiology. The study indicates that the virus HCoV-EMC can penetrate the lining of the passageways in the lung and evade the innate immune system as easily as a cold virus can, signs that HCoV-EMC is well-equipped for infecting human cells. The study also reveals that the virus is susceptible to treatment ...

The advancement of women in leadership has fundamentally shaped the business landscape, and Stiletto Woman Media celebrates this evolving influence. The company's mission to empower women in business has flourished into an effort that cultivates leaders and contributes to the progression of business owners and independent professionals. Stiletto Woman In Business Awards (SWIBA) is a nationally recognized comprehensive awards program that exclusively honors women in the micro business sector. Known for its influential reach, this initiative commemorates prolific leaders ...

Joseph Spinella, international tenor sensation, performs a special music and magic show in Venice, Florida for 16 shows starting on March 7, 2013. Returning from his recording sessions with the Macedonian Radio Symphonic Orchestra, Spinella sings classic Neapolitan songs from his latest album and performs exhilarating magic illusions on-stage. The show starts out with a spot-on impersonation of Luciano Pavarotti and goes into a quick-change to a Venetian gondola. He sings in this magnificent tenor voice and performs magic as his assistant comes on stage and then disappears ...

Roderick Hubbard, long-time expert in the field of drug design, will deliver the keynote address at GTC's 7th Drug Design & Medicinal Chemistry Conference, to be held May 8-10, 2013 in Boston, MA. Professor Hubbard, who divides his time between academic research at the York Structural Biology Laboratory and applied research at the pharmaceutical company Vernalis, has a unique and balanced perspective of drug discovery in both academia and industry. He will review recent developments in the field during his presentation, "Current Perspectives in Fragment-Based ...

NC Beautiful has announced that Bobby Cremins will serve as Honorary Chair of the 28th NC Beautiful Golf Classic. The environmental non-profit's fundraiser will be held from July 19-21 at Pinehurst Resort & Spa, one of the world's finest golf resorts located among the Sandhills of North Carolina. Cremins is a veteran of 31 seasons as a college basketball head coach. Cremins graduated from the University of South Carolina in 1970 and played professional basketball in Ecuador before beginning his collegiate coaching career at Point Park College in Pittsburgh, PA in ...

Urban Psalmist and Artist Kevin Gray is coming back, guns blazing with his fourth project, "Chapter Next" which will be releasing Summer 2013. The first single "Fill This Temple" which was written by Darrel Walls of The Walls Group is set to drop digitally everywhere March 5th. Kevin is very confident that his fans and new listeners will enjoy this energetic worship infused single. He adds that Fill This Temple is a song that in its pure simplicity evokes the magnitude presence of God. "Chapter Next" will consist of Kevin's signature R&B ...

Organisers of the inaugural 2013 Phuket ITU Long Distance Triathlon Series event presented by the Absolute World Group are proud to announce that Phuket has been chosen as host of the Long Distance Triathlon Series (LD) event under the International Triathlon Union (ITU) banner. The event is part of a triathlon weekend on Phuket which will take place 9th and 10th November in Patong, Phuket, Thailand. The weekend starts with a Sprint triathlon (750m swim, 20km bike, 5km run), Olympic Distance triathlon (1.5km/ 40km/ 10km) and relay events on Saturday 9th November, followed ...

On February 18, 2013, Real Senior Living Reviews (RSLR) is launching its online review site for the senior care industry. Real Senior Living Reviews allows companies in the senior care industry to put their reviews directly on their website. Besides online reviews, RSLR also helps senior care companies build and maintain an online reputation management system. For more information, visit http://www.realseniorlivingreviews.com Real Senior Living Reviews' mission, unlike other review sites, is focused on the companies rather than the reviewers and end users. Their mission ...

Due to the success it experienced last year, MPGQS has been invited to return to this years event which is expected to attract more than 4,000 investors globally. MIPIM is the largest event of its kind in the world, held annually in Cannes, France. As a result of attending in 2012, MPGQS was appointed as the monitoring and evaluation expert for the Telephone House in London, awarded a commercial role for MEP contractors on Doha Land, and provided a dispute resolution service to an electrical contractor on the FSA building. The company is hoping for similar success ...

VA Investment Software would like to announce that it has released 6 Value Averaging (VA) back testing analysis reports. The reports show how an investor would have done by investing using VA compared to dollar cost averaging or investing a lump sum over the last 5 years. The results of the reports shows that VA definitely offers investors a better alternative to other stock market investment methods with less risk. VA helps investors to invest in 2 ways: 1. by helping investors invest a lump sum of capital over time and 2. by helping investors accumulate a target amount ...

Fresh off several successful speaking engagements, window fashion expert, Deb Barrett is slated to speak at the several upcoming Design Arts events. Barrett is scheduled with Design Arts Seminars for presentations in Fort Lauderdale, February 22, 2013, and San Antonio, March 14, 2013, Dallas, May 16, 2013 and Houston, June 6, 2013. During her program, "High Impact Materials for High Income Projects", Ms. Barrett will share thoughtful, innovative ideas, materials and processes design professionals can work into their own projects to wow clients, increase sales ...

2013 has begun on a great note for Calgary with 80 participants collaborating to create 11 new startups at the recently concluded Startup Weekend. Startup Weekend is a global grassroots movement of active and empowered entrepreneurs who are learning the basics of founding startups and launching successful ventures. It is the largest community of passionate entrepreneurs with over 400 past events in 100 countries around the world in 2012. The concept is simple - people get together on a Friday evening and pitch startup ideas, the community votes for the ideas they'd like ...

Single women are invited to swap the finest bachelors they know, with whom they are NOT romantically involved (brothers, fathers, sons, co-workers, ex-husbands, etc.), Saturday, March 9, 2013, 8pm-Midnight, at the Marriott Hotel, 11950 Dublin Canyon Blvd, Pleasanton, CA. The cost is $20 at the door, which includes dancing to your favorite hits. As an incentive, each man/woman pair who RSVP receive 2-for-1 admission, $10 apiece. "Many women believe that all the men in the Bay Area are either married, gay, or dead," says Rich Gosse, Chairman of The Society of ...

Mold consultant Phillip Fry has introduced the newly-updated Worldwide Directory of Certified Mold Inspectors and Environmental and Industrial Hygienists for the mold and environmental inspection and testing of residences, commercial buildings, and public buildings in the USA, Canada, Philippines, Asia, Europe, Middle East, and Africa. The directory is available at http://www.certifiedmoldinspectors.com. The listed mold inspectors and hygienists have been trained and certified by the Environmental Hygienists Association (E.H.A.) at http://www.ecology-college.com. Phillip ...

Don McCauley of the Free Publicity Focus Group and Danielle Hampson of eBroadcastMedia.com, founders of Book Marketing, announced today The Authors Show radio and TV weekly broadcast schedule. Book Marketing, branded as 'The Authors Marketing Powerhouse', allows authors and publishers the opportunity to upload photos, bios, book covers, video and book videos. The site also offers discussion forums, segmented special interest groups and allows for event listings. Each author can develop a personalized page. In addition the site allows for integration with Facebook and ...

Alexander brings with him extensive experience in residential and commercial property, modernisation contracts, school developments, upgrades, extensions and new build, tender submission and evaluation, BIM cost modelling, ISO 9001 certification, risk management policy and value engineering. A graduate from Heriot-Watt University in Edinburgh, Alexander has an MSc in Construction Project Management. He also holds a certificate in Management of Risk and Uncertainty and has a BSc in Economics and Management of Industrial Enterprise. Michael Gallucci, Chairman of MPG, ...

W2 and 1099 software developer Halfpricesoft.com has added the pdf printing feature and e-file feature to its new edition of ezW2 software for 2013 tax season. With all the forms and paperwork necessary, tax season may be the most environmentally unfriendly part of the year for businesses. Halfpricesoft.com developers hope this W2 and 1099 software can add a little Green to this bleak season with electronic PDF printing and e-file features that save time, money and the environment. - ezW2 2012 can print ALL W-2 forms (copy A, B, C, D, 1 and 2) and W-3 forms on plain ...

Belli is now available at 130 Destination Maternity and A Pea in the Pod Maternity stores across the U.S. The Belli Skincare line includes an assortment of specially formulated beauty products that CLEANSE, TREAT, HYDRATE and PROTECT a woman's skin during and after her pregnancy. Belli Skincare products feature effective, safety-screened ingredients designed to help expectant mothers achieve a healthy, glowing complexion. The Belli line includes a regimen of complementary facial skin care products for hormonal acne, dry skin and uneven skin tone, with products ranging in ...

Celebrity HotSpots introduces expanded platform, http://www.celebhotspots.com, featuring an easy-to-use searchable proprietary database filled with over 85,000 documented celebrity spottings over the past few years, with new sightings added daily. The one-of-a-kind searchable database features more than 3000 hotspots from around the world, especially in Los Angeles, New York, Las Vegas, Miami and London. Fans can discover where their favorite celebrities hang, eat, and socialize—anyone can live like a celebrity with Celebrity HotSpots. Susan Zechter, Founder of ...

Many patients report oral pain, and many more Canadians who have oral pain go untreated. Oral pain causes patients to miss school, which results in interrupted learning and lowered grades. Oral pain can also keep adults from work, which results in decreased pay. A new study by the University of Toronto and McGill University researchers examines the variables that determine oral pain among the Canadian population. Our team that offers dentistry in Kanata at Trillium Dental, understands how oral pain affects patients and works hard to relieve oral pain and improve oral ...