GALVESTON, Texas — Prescriptions for testosterone therapy have increased significantly during the last 10 years, according to a study in the current issue of JAMA Internal Medicine conducted by researchers at the University of Texas Medical Branch. About 50 percent of the men in the study who had received testosterone therapy had been diagnosed as having hypogonadism, a condition where a man is unable to produce the normal levels of testosterone. But the study also found that, among new users of a prescription androgen product, about 25 percent did not have their testosterone ...

Using cholesterol-lowering statins may be associated with musculoskeletal conditions, arthropathies (joint diseases) and injuries, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication. While statins effectively lower cardiovascular illnesses and death, the full spectrum of statin musculoskeletal adverse events (AEs) is unknown. Statin-associated musculoskeletal AEs include a wide variety of clinical presentations, including muscle weakness, muscle cramps and tendinous (tendon) diseases, the authors write in the study background. Ishak ...

Vegetarian diets are associated with reduced death rates in a study of more than 70,000 Seventh-day Adventists with more favorable results for men than women, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication. The possible relationship between diet and mortality is an important area of study. Vegetarian diets have been associated with reductions in risk for several chronic diseases, including hypertension, metabolic syndrome, diabetes mellitus and ischemic heart disease (IHD), according to the study background. Michael ...

Racial and ethnic disparities in children who are overweight and obese may be determined by risk factors in infancy and early childhood, according to a study published Online First by JAMA Pediatrics, a JAMA Network publication. Over three decades, the rates of overweight and obesity among children have substantially increased worldwide. In the United States, the prevalence is estimated to be 32 percent among children and adolescents, according to the study background. Elsie M. Taveras, M.D., M.P.H., now of the MassGeneral Hospital for Children, Boston, and colleagues ...

A study by Helen Wong, R.D., of The Hospital for Sick Children, Ontario, Canada, and colleagues examined the safety and efficacy of dietary flaxseed supplementation in the management of hypercholesterolemia (high levels of cholesterol) in children. (Online First) The randomized clinical trial included 32 participants ages 8 to 18 years with low-density lipoprotein cholesterol levels ranging from 135 mg/dL to less than 193 mg/dL. Participants were randomly assigned to either the intervention group or control group. The intervention group ate 2 muffins and 1 slice of bread ...

A study by Hans-Peter Hartung, M.D., of Heinrich-Heine-Universität, Düsseldoft, Germany, and colleagues examines the association between IL-17F and treatment response to interferon beta-1b among patients with relapsing-remitting multiple sclerosis. (Online First) Serum samples were analyzed with an immunoassay from 239 randomly selected patients treated with interferon beta-1b, 250 micrograms, for at least 2 years in the Betaferon Efficacy Yielding Outcomes of a New Dose Study. Researchers measured the levels of IL-17F at baseline and month 6, as well as the difference ...

Employers have to pay around £4,000 more a year to employ a member of staff who smokes compared to a non-smoking employee, finds research published online in the Tobacco Control journal. US researchers found that several factors including absenteeism, smoking breaks and healthcare costs result in a greater cost to the employer for having a smoker on staff and this cost could help inform their workplace tobacco policies. The risks to a person's health from smoking include a higher risk of developing cancer, heart or lung disease and currently around 10 million adults ...

Around half of people with an extreme form of obsessive compulsive disorder responded well to a type of psychosurgery that proved to be safe and effective, according to research published online in the Journal of Neurology, Neurosurgery, & Psychiatry. Researchers from Canada have now recommended physicians should consider this approach in helping people with OCD who have not responded to any other type of treatment. Obsessive compulsive disorder (OCD) is a psychiatric disease which leads to anxiety-provoking thoughts (obsessions) causing repeated, time-consuming behaviors ...

Less than half of terminally ill patients are placed on the Liverpool Care Pathway for the Dying Patient (LCP) despite it being recommended nationally, concludes UK research published online in the BMJ Supportive & Palliative Care journal. Durham University researchers found that in many parts of England, staff may have limited training or support to use the care pathway, which is a model of care that enables healthcare professionals to focus on care in the last hours or days of life when a death is expected. The pathway was jointly developed by the Marie Curie Hospice ...

Scientists have discovered a new enzyme that could prove an important step in the quest to turn waste (such as paper, scrap wood and straw) into liquid fuel. To do this they turned to the destructive power of tiny marine wood-borers called 'gribble', which have been known to destroy seaside piers. Using advanced biochemical analysis and X-ray imaging techniques, researchers from the University of York, University of Portsmouth and the National Renewable Energy Laboratory in the USA have determined the structure and function of a key enzyme used by gribble to break down ...

4th June 2013, Zaragoza, Spain – Alzheimer researchers in Spain have taken a step closer to finding a blood test to help in the diagnosis of Alzheimer's disease. With approximately 75% of the estimated 36 million Alzheimer's sufferers worldwide yet to receive a reliable diagnosis, the potential impact on the lives of possible sufferers, present and future, could be huge. Alzheimer's disease is a neurodegenerative disease most frequently affecting the elderly. The most commonly associated symptom is a progressive loss of memory to the stage in which the patient is ...

COLUMBUS, Ohio – A new study suggests that U.S. businesses pay almost $6,000 per year extra for each employee who smokes compared to the cost to employ a person who has never smoked cigarettes. Researchers say the study is the first to take a comprehensive look at the financial burden for companies that employ smokers. By drawing on previous research on the costs of absenteeism, lost productivity, smoke breaks and health care costs, the researchers developed an estimate that each employee who smokes costs an employer an average of $5,816 annually above the cost of ...

Our Solar System's Milky Way neighborhood just went upscale. We reside between two major spiral arms of our home galaxy, in a structure called the Local Arm. New research using the ultra-sharp radio vision of the National Science Foundation's Very Long Baseline Array (VLBA) indicates that the Local Arm, previously thought to be only a small spur, instead is much more like the adjacent major arms, and is likely a significant branch of one of them. "Our new evidence suggests that the Local Arm should appear as a prominent feature of the Milky Way," said Alberto Sanna, of ...

Even if Australians with newly diagnosed bowel cancer were routinely tested for a genetic predisposition to further cancers, one in three people would still not take the necessary steps to use that information to prevent further disease. Researchers from UNSW Medicine took the extra step of screening for the hereditary Lynch syndrome in the 2,100 people with colorectal cancer who presented at a number of NSW hospitals* over a three-year period. Researchers found that a significant number of these people (245) had a bowel cancer with features that suggested Lynch syndrome, ...

There is an increasing need for safe emergency anaesthesia as cases of emergency Caesarean section (CS) continue to rise, say experts speaking at Euroanaesthesia, the annual congress of the European Society of Anaesthesiology (ESA). Dr Geraldine O'Sullivan (Lead clinician for obstetric anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK) discusses how in the UK between 25-30% of deliveries are by CS, well above the WHO recommended rate of 15% (England 25%, Scotland/Wales 26%, Northern Ireland 30%, UK overall 25%). The 25% overall rate in the UK is made ...

U.S. workfare programs have been praised by some for cutting welfare rolls and improving the economic well-being of families. But little is known about how these policies affected participants' health and mortality. Researchers at Columbia University's Mailman School of Public Health studied enrollees in Florida's Family Transition Program who were given a time limit for welfare benefits and exposed to job training. They were compared to a control group who received traditional welfare benefits. In this randomized controlled trial, the researchers found that participants ...

ROCHESTER, Minn. -- Go ye and sin no more -- or pay for it, when it comes to junk food, smoking and consuming alcohol. That's the message from two Mayo Clinic physicians who say raising "sin" taxes on tobacco and alcoholic beverages and imposing them on sugary drinks and fatty foods would lead many people to cut back, improving public health. The article by Michael Joyner, M.D., and David Warner, M.D., appears in the June issue of the journal Mayo Clinic Proceedings. The physicians contend that much of overall health depends on behavior and is relatively independent of ...

The long-standing mystery behind dormant disseminated breast tumor cells and what activates them after years and even decades of latency may have been solved. Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified the microenvironment surrounding microvasculature – the small blood vessels that transport blood within tissues – as a niche where dormant cancer cells reside. When these blood vessels begin to sprout, the new tips produce molecules that transform dormant cancer cells into metastatic tumors. In ...

In a bid to save £10 million a year the British Treasury is replacing copper–nickel five and ten pence coins with new nickel-plated steel versions. However, while no UK health assessment has taken place, scientists in Sweden have analyzed the allergy risk after the Swedish state bank announced it will reduce traces of nickel in Swedish coinage. The assessment, published in Contact Dermatitis reveals that the UK public's exposure to nickel allergic reactions will increase four fold. The team analyzes skin exposure and metal release in artificial sweat to find that the ...

(PHILADELPHIA) – Research from Thomas Jefferson University is laying the foundation for a genetic test to accurately identify hip dysplasia in newborns so that early intervention can be initiated to promote normal development. This research from Jefferson Orthopedics physician-scientists is currently available in the Journal of Bone and Mineralizing Research (JBMR) online at http://onlinelibrary.wiley.com/doi/10.1002/jbmr.1999/abstract. The researchers studied four generations of a Utah family affected by developmental dysplasia of the hip (DDH) in most generations. ...

In a report to be released this month, the Promoting Malaria Prevention and Treatment (ProMPT) Project will describe an innovative model for distributing over 12 million mosquito nets to prevent the transmission of malaria in Ghana. In collaboration with the Ghana Health Service (GHS), and funding from the US Agency for international Development (USAID), the four year long project ensured that millions of households learned how to use nets treated with insecticide to kill mosquitoes, which can transmit malaria. The $20 million project, funded through the United States ...

ITHACA, N.Y. – Preschoolers universally recognize that one's choices are not always free – that our decisions may be constrained by social obligations to be nice to others or follow rules set by parents or elders, even when wanting to do otherwise. As they age, however, American kids are more prone to acknowledge one's freedom to act against such obligations compared to Nepalese children, who are less willing to say that people can and will violate social codes, finds a cross-cultural study by Cornell University development psychologists published in the current issue ...

Fish can hide in the open ocean by manipulating how light reflects off their skin, according to researchers at The University of Texas at Austin. The discovery could someday lead to the development of new camouflage materials for use in the ocean, and it overturns 40 years of conventional wisdom about fish camouflage. The researchers found that lookdown fish camouflage themselves through a complex manipulation of polarized light after it strikes the fishes' skin. In laboratory studies, they showed that this kind of camouflage outperforms by up to 80 percent the "mirror" ...

(WINSTON-SALEM, NC, June 3, 2013) – When it comes to saving its own hide, the tiger moth can predict the future. A new study by researchers at Wake Forest University shows Bertholdia trigona, a species of tiger moth found in the Arizona desert, can tell if an echo-locating bat is going to attack it well before the predator swoops in for the kill – making the intuitive, tiny-winged insect a master of self-preservation. Predators in the night A bat uses sonar to hunt at night. The small mammal emits a series of ultrasonic cries and listens carefully to the echoes ...

This news release is available in German. The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish 12 new Collaborative Research Centres (CRCs). This was decided by the responsible Grants Committee during its spring session in Bonn. The new CRCs will receive a total of 94 million euros for an initial period of three years and nine months. There will also be a 20% programme allowance for indirect project costs. The new CRCs cover a wide range of topics, including the sociocultural importance of oil, metals, food and other natural resources ...