Sustainable new catalysts fueled by a single proton
2013-02-14
CHESTNUT HILL, MA (Feb. 14, 2013) – Chemists at Boston College have designed a new class of catalysts triggered by the charge of a single proton, the team reports in the most recent edition of the journal Nature. The simple organic molecules offer a sustainable and highly efficient platform for chemical reactions that produce sets of molecules crucial to advances in medicine and the life sciences.
Unearthing a reliable, truly general, efficient synthesis of single mirror-image isomers has proven elusive. Previous methods suffer from a combination of extreme temperatures, ...
'Significant' proportion of HIV positive patients may not be telling NHS staff about their infection
2013-02-14
A significant proportion of HIV positive patients may not be disclosing their infection to NHS staff, when turning up for treatment at sexual health clinics, suggests preliminary research published online in the journal Sexually Transmitted Infections.
If the findings reflect a national trend, this could have implications for the true prevalence of undiagnosed HIV infection in the population, which is based on the numbers of "undiagnosed" patients at sexual health clinics, say the authors.
Currently, it is estimated that around one in four people in the UK who is HIV ...
California's Tobacco Control Program generates huge health care savings, UCSF study shows
2013-02-14
Over a span of nearly 20 years, California's tobacco control program cost $2.4 billion and reduced health care costs by $134 billion, according to a new study by UC San Francisco.
Additionally, the study -- covering the beginning of the program in 1989 to 2008 -- found that the state program helped lead to some 6.8 billion fewer packs of cigarettes being sold that would have been worth $28.5 billion in sales to cigarette companies.
The study was designed to calculate the fiscal impact of California's large public health program on smoking prevalence and cigarette consumption. ...
Cracking the semantic code
2013-02-14
We make choices about pretty much everything, all the time – "Should I go for a walk or grab a coffee?"; "Shall I look at who just came in or continue to watch TV?" – and to do so we need something common as a basis to make the choice.
Dr John Fennell and Dr Roland Baddeley of Bristol's School of Experimental Psychology followed a hunch that the common quantity, often referred to simply as reward, was a representation of what could be gained, together with how risky and uncertain it is. They proposed that these dimensions would be a unique feature of all objects and ...
Finding 'Mr. Right,' how insects sniff out the perfect mate
2013-02-14
TEMPE, Ariz. – You may want to ramp up your romance this year by sharing a candlelight dinner, a walk on the beach, or even the scent of a perfume, but will that help you find your perfect mate? For one wasp species, it only takes a whiff of his special love potion to know whether he's "Mr. Right."
Unlike humans, most insects rely on their sense of smell when looking for a mate. Scientists have found that sex pheromones play an important role in finding a suitable partner of the same species; yet, little is known about the evolution and genetic basis of these alluring ...
Scientists discover how animals taste, and avoid, high salt concentrations
2013-02-14
New York, NY (February 13, 2013) —For consumers of the typical Western diet—laden with levels of salt detrimental to long-term health—it may be hard to believe that there is such a thing as an innate aversion to very high concentrations of salt.
But Charles Zuker, PhD, and colleagues at Columbia University Medical Center have discovered how the tongue detects high concentrations of salt (think seawater levels, not potato chips), the first step in a salt-avoiding behavior common to most mammals.
The findings could serve as a springboard for the development of taste ...
A war without end -- with Earth's carbon cycle held in the balance
2013-02-14
CORVALLIS, Ore. – The greatest battle in Earth's history has been going on for hundreds of millions of years, isn't over yet, and until now no one knew it existed, scientists reported today in the journal Nature.
In one corner is SAR11, a bacterium that's the most abundant organism in the oceans, survives where most other cells would die and plays a major role in the planet's carbon cycle. It had been theorized that SAR11 was so small and widespread that it must be invulnerable to attack.
In the other corner, and so strange looking that scientists previously didn't ...
Penn geologists quantify, characterize sediment carried by Mississippi flood to Louisiana's wetlands
2013-02-14
PHILADELPHIA — The spring 2011 flood on the Mississippi was among the largest floods ever, the river swelling over its banks and wreaking destruction in the surrounding areas. But a University of Pennsylvania-led study also shows that the flood reaped environmental benefits — transporting and laying down new sediment in portions of the Delta — that may help maintain the area's wetlands.
The study, led by Ph.D. student Nicole Khan of the Department of Earth and Environmental Science, is the first to quantify the amount of sediment transported to wetlands by a flood on ...
Happily married couples consider themselves healthier, expert says
2013-02-14
COLUMBIA, Mo. – Research shows that married people have better mental and physical health than their unmarried peers and are less likely to develop chronic conditions than their widowed or divorced counterparts. A University of Missouri expert says that people who have happy marriages are more likely to rate their health as better as they age; aging adults whose physical health is declining could especially benefit from improving their marriages.
Christine Proulx, an assistant professor in the MU Department of Human Development and Family Studies, examined the long-term ...
Facial structure may predict endorsement of racial prejudice
2013-02-14
The structure of a man's face may indicate his tendency to express racially prejudiced beliefs, according to new research published in Psychological Science, a journal of the Association for Psychological Science.
Studies have shown that facial width-to-height ratio (fWHR) is associated with testosterone-related behaviors, which some researchers have linked with aggression. But psychological scientist Eric Hehman of Dartmouth College and colleagues at the University of Delaware speculated that these behaviors may have more to do with social dominance than outright aggression.
The ...
NASA scientists part of Arctic Sea ice study
2013-02-14
New research using combined records of ice measurements from NASA's Ice, Cloud and Land Elevation Satellite (ICESat), the European Space Agency's CryoSat-2 satellite, airborne surveys and ocean-based sensors shows Arctic sea ice volume declined 36 percent in the autumn and 9 percent in the winter over the last decade. The work builds on previous studies using submarine and NASA satellite data and confirms computer model estimates that showed ice volume decreases over the last decade, and builds a foundation for a multi-decadal record of sea ice volume changes.
In a report ...
Resignation of Pope Benedict XVI demands a close look at rules of modern papal election
2013-02-14
New Rochelle, NY, February 13, 2013—When Pope Benedict XVI ends his reign at the end of February he will be the first pope to do so before his death in nearly 600 years. He shocked the Catholic Church by announcing his resignation and set in place a centuries-old process to select his successor. The fascinating Conclaves system for electing a new pope, which has been in place since the late 1200s is described in "Creating the Rules of the Modern Papal Election," published in Election Law Journal, from Mary Ann Liebert, Inc., publishers. The article is available on the Election ...
Why there are bad learners: EEG activity predicts learning success
2013-02-14
The reason why some people are worse at learning than others has been revealed by a research team from Berlin, Bochum, and Leipzig, operating within the framework of the Germany-wide network "Bernstein Focus State Dependencies of Learning". They have discovered that the main problem is not that learning processes are inefficient per se, but that the brain insufficiently processes the information to be learned. The scientists trained the subjects' sense of touch to be more sensitive. In subjects who responded well to the training, the EEG revealed characteristic changes ...
Genetic study pursues elusive goal: How many humpbacks existed before whaling?
2013-02-14
Scientists from Stanford University, the Wildlife Conservation Society, the American Museum of Natural History, and other organizations are closing in on the answer to an important conservation question: how many humpback whales once existed in the North Atlantic?
Building on previous genetic analyses to estimate the pre-whaling population of North Atlantic humpback whales, the research team has found that humpbacks used to exist in numbers of more than 100,000 individuals. The new, more accurate estimate is lower than previously calculated but still two to three times ...
Robots with lift
2013-02-14
They can already stand, walk, wriggle under obstacles, and change colors. Now researchers are adding a new skill to the soft robot arsenal: jumping.
Using small explosions produced by a mix of methane and oxygen, researchers at Harvard have designed a soft robot that can leap as much as a foot in the air. That ability to jump could one day prove critical in allowing the robots to avoid obstacles during search and rescue operations. The research is described in a Feb. 6 paper in the international edition of Angewandte Chemie.
"Initially, our soft robot systems used pneumatic ...
Study supports regulation of hospitals
2013-02-14
EAST LANSING, Mich. — Hospital beds tend to get used simply because they're available – not necessarily because they're needed, according to a first-of-its-kind study that supports continued regulation of new hospitals.
Michigan State University researchers examined all 1.1 million admissions at Michigan's 169 acute-care hospitals in 2010 and found a strong correlation between bed availability and use, even when accounting for myriad factors that may lead to hospitalization. These factors include nature of the ailment, health insurance coverage, access to primary care ...
Clues to chromosome crossovers
2013-02-14
Neil Hunter's laboratory in the UC Davis College of Biological Sciences has placed another piece in the puzzle of how sexual reproduction shuffles genes while making sure sperm and eggs get the right number of chromosomes.
The basis of sexual reproduction is that a fertilized egg gets half its chromosomes from each parent — sperm and eggs each contributing one partner in each pair of chromosomes. We humans have 23 pairs of 46 chromosomes: so our sperm or eggs have 23 chromosomes each.
Before we get to the sex part, though, those sperm and eggs have to be formed from ...
Preventing obesity transmission during pregnancy
2013-02-14
A much neglected part of the obesity epidemic is that it has resulted in more overweight/obese women before and during pregnancy. Their offspring also tend to have higher birth weights and more body fat, and carry an increased risk of obesity and chronic diseases later in life. However, the nutritional factors and mechanisms involved pre and during pregnancy that may influence child obesity remain uncertain. A recent publication by ILSI Europe identifies and discusses key contributing factors leading to obesity.
In an article recently published in Annals of Nutrition and ...
Probiotic-derived treatment offers new hope for premature babies
2013-02-14
BETHESDA, Md. (Feb. 13, 2013)—"Good" bacteria that live in our intestines have been linked with a variety of health benefits, from fighting disease to preventing obesity. In a new study, Kriston Ganguli of Massachusetts General Hospital for Children and Harvard Medical School and her colleagues have discovered another advantage to these friendly microscopic tenants: Chemicals secreted by good bacteria that typically live in the intestines of babies could reduce the frequency and severity of a common and often-lethal disease of premature infants.
This disease, known as ...
Marsh plants actively engineer their landscape
2013-02-14
DURHAM, NC -- Marsh plants, far from being passive wallflowers, are "secret gardeners" that actively engineer their landscape to increase their species' odds of survival, says a team of scientists from Duke University and the University of Padova in Italy.
Scientists have long believed that the distribution of plants within a marsh is a passive adaption in which species grow at different elevations because that's where conditions like soil aeration and salinity best meet their needs.
But this team found intertidal marsh plants in Italy's famed Venetian lagoon were ...
Cellular renewal process may underlie benefits of omega fatty acids
2013-02-14
A search for genes that change their levels of expression in response to nutrient deprivation has uncovered potential clues to the mechanism underlying the health benefits of omega fatty acids. In the Feb. 15 issue of Genes & Development, Massachusetts General Hospital (MGH) researchers describe finding that feeding omega-6 fatty acids to C. elegans roundworms or adding them to cultured human cells activates a cellular renewal process called autophagy, which may be deficient in several important diseases of aging. A process by which defective or worn-out cellular components ...
Vanderbilt study reveals clues to childhood respiratory virus
2013-02-14
New Vanderbilt-led research published in the Feb. 14 issue of the New England Journal of Medicine has identified the relatively unknown human metapneumovirus (MPV) as the second most common cause of severe bronchiolitis in young children.
Senior author John Williams , M.D., associate professor of Pediatric Infectious Diseases and a well-known expert in MPV research, said it is gratifying to offer a clearer picture of how this virus impacts children.
"We found MPV is as important a cause of respiratory illness as influenza, and caused more illness than the three common ...
Rewiring the serotonin system
2013-02-14
An interdisciplinary team of researchers from the University of Texas Medical Branch at Galveston and the University of Houston has found a new way to influence the vital serotonin signaling system — possibly leading to more effective medications with fewer side effects.
Scientists have linked malfunctions in serotonin signaling to a wide range of health issues, everything from depression and addictions to epilepsy and obesity and eating disorders. Much of their attention has focused on complex proteins called serotonin receptors, which are located in the cell membrane. ...
Light-emitting bioprobe fits in a single cell
2013-02-14
If engineers at Stanford have their way, biological research may soon be transformed by a new class of light-emitting probes small enough to be injected into individual cells without harm to the host. Welcome to biophotonics, a discipline at the confluence of engineering, biology and medicine in which light-based devices – lasers and light-emitting diodes (LEDs) – are opening up new avenues in the study and influence of living cells.
The team described their probe in a paper published online February 13 by the journal Nano Letters. It is the first study to demonstrate ...
Recent marijuana use in HIV-infected Russians associated with increased sex and drug risk behaviors
2013-02-14
(Boston) – Researchers from Boston Medical Center (BMC) and Boston University's School of Medicine (BUSM) and School of Public Health (BUSPH) have found that in Russian HIV-infected risky drinkers, marijuana use is associated with other increased risky behaviors involving drug use and sex. These findings, published online in the journal Drug and Alcohol Dependence, may aid clinicians and public health experts in detecting individuals at a higher risk of transmitting HIV.
Marijuana, otherwise known as cannabis, is the most frequently used illicit drug worldwide. Previous ...
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