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NIH study provides clarity on supplements for protection against blinding eye disease

2013-05-06
Adding omega-3 fatty acids did not improve a combination of nutritional supplements commonly recommended for treating age-related macular degeneration (AMD), a major cause of vision loss among older Americans, according to a study from the National Institutes of Health (NIH). The plant-derived antioxidants lutein and zeaxanthin also had no overall effect on AMD when added to the combination; however, they were safer than the related antioxidant beta-carotene, according to the study published online today in the Journal of the American Medical Association. "Millions of ...

'Look but don't touch'

2013-05-06
Improving our understanding of the human brain, gathering insights into the origin of our universe through the detection of gravitational waves, or optimizing the precision of GPS systems- all are difficult challenges to master because they require the ability to visualize highly fragile elements, which can be terminally damaged by any attempt to observe them. Now, quantum physics has provided a solution. In an article published in Nature Photonics, researchers at the Institute of Photonic Sciences (ICFO) report the observation of a highly fragile and volatile body through ...

Organic vapors affect clouds leading to previously unidentified climate cooling

2013-05-06
University of Manchester scientists, writing in the journal Nature Geoscience, have shown that natural emissions and manmade pollutants can both have an unexpected cooling effect on the world's climate by making clouds brighter. Clouds are made of water droplets, condensed on to tiny particles suspended in the air. When the air is humid enough, the particles swell into cloud droplets. It has been known for some decades that the number of these particles and their size control how bright the clouds appear from the top, controlling the efficiency with which clouds scatter ...

Improving materials that convert heat to electricity and vice-versa

2013-05-06
ANN ARBOR---Thermoelectric materials can be used to turn waste heat into electricity or to provide refrigeration without any liquid coolants, and a research team from the University of Michigan has found a way to nearly double the efficiency of a particular class of them that's made with organic semiconductors. Organic semiconductors are carbon-rich compounds that are relatively cheap, abundant, lightweight and tough. But they haven't traditionally been considered candidate thermoelectric materials because they have been inefficient in carrying out the essential heat-to-electricity ...

Protein complex may play role in preventing many forms of cancer, Stanford study shows

2013-05-06
STANFORD, Calif. - Researchers at the Stanford University School of Medicine have identified a group of proteins that are mutated in about one-fifth of all human cancers. The finding suggests that the proteins, which are members of a protein complex that affects how DNA is packaged in cells, work to suppress the development of tumors in many types of tissues. The broad reach of the effect of mutations in the complex, called BAF, rivals that of another well-known tumor suppressor called p53. It also furthers a growing notion that these so-called chromatin-regulatory complexes ...

Portable device provides rapid, accurate diagnosis of tuberculosis, other bacterial infections

2013-05-06
A handheld diagnostic device that Massachusetts General Hospital (MGH) investigators first developed to diagnose cancer has been adapted to rapidly diagnose tuberculosis (TB) and other important infectious bacteria. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe portable devices that combine microfluidic technology with nuclear magnetic resonance (NMR) to not only diagnose these important infections but also determine the presence of antibiotic-resistant bacterial strains. "Rapidly identifying the pathogen responsible for ...

Study evaluates effect of different supplements on reducing risk of progression to advanced AMD

2013-05-06
In a large, multicenter, randomized clinical trial that included persons at high risk for progression to advanced age-related macular degeneration (AMD), adding the carotenoids lutein and zeaxanthin, the omega-3 fatty acids DHA and EPA, or both to a formulation of antioxidant vitamins and minerals that has shown effectiveness in reducing risk did not further reduce risk of progression to advanced AMD, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the Association for Research in Vision and Ophthalmology ...

Discovery helps show how breast cancer spreads

2013-05-06
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis. It has long been known that women with denser breasts are at higher risk for breast cancer. This greater density is caused by an excess of a structural protein called collagen. "We have shown how increased collagen in the breasts could increase the chances of breast tumors spreading and becoming more ...

Discovery may help prevent chemotherapy-induced anemia

2013-05-06
May 5, 2013 — (Bronx, NY) — Cancer chemotherapy can cause peripheral neuropathy—nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that chemo also induces an insidious type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation. The findings, made in mice and published online today in Nature Medicine, suggest that combining chemotherapy with nerve-protecting agents may prevent long-term bone marrow injury ...

Epilepsy cured in mice using brain cells

2013-05-06
UCSF scientists controlled seizures in epileptic mice with a one-time transplantation of medial ganglionic eminence (MGE) cells, which inhibit signaling in overactive nerve circuits, into the hippocampus, a brain region associated with seizures, as well as with learning and memory. Other researchers had previously used different cell types in rodent cell transplantation experiments and failed to stop seizures. Cell therapy has become an active focus of epilepsy research, in part because current medications, even when effective, only control symptoms and not underlying ...

Microwave oven cooks up solar cell material

2013-05-06
SALT LAKE CITY, May 6, 2013 – University of Utah metallurgists used an old microwave oven to produce a nanocrystal semiconductor rapidly using cheap, abundant and less toxic metals than other semiconductors. They hope it will be used for more efficient photovoltaic solar cells and LED lights, biological sensors and systems to convert waste heat to electricity. Using microwaves "is a fast way to make these particles that have a broad range of applications," says Michael Free, a professor of metallurgical engineering. "We hope in the next five years there will be some commercial ...

Flame retardants may be toxic to children

2013-05-06
WASHINGTON, DC – Chemicals called polybrominated diphenyl ethers (PBDEs) have been used for decades to reduce fires in everyday products such as baby strollers, carpeting and electronics. A new study to be presented on Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting shows that prenatal exposure to the flame retardants is associated with lower intelligence and hyperactivity in early childhood. "In animal studies, PBDEs can disrupt thyroid hormone and cause hyperactivity and learning problems," said lead author Aimin Chen, MD, PhD, assistant professor ...

Teen girls who exercise are less likely to be violent

2013-05-06
WASHINGTON, DC – Regular exercise is touted as an antidote for many ills, including stress, depression and obesity. Physical activity also may help decrease violent behavior among adolescent girls, according to new research to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. Researchers from Columbia University analyzed results of a 2008 survey completed by 1,312 students at four inner-city high schools in New York to determine if there was an association between regular exercise and violence-related behaviors. "Violence ...

High school athletes say concussions won't sideline them

2013-05-06
WASHINGTON, DC – Many high school football players say it's OK to play with a concussion even though they know they are at risk of serious injury, according to a study to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. The study of 120 high school football players in the Cincinnati area also found that one-quarter had suffered a concussion, and more than half acknowledged they would continue to play with symptoms of a concussion. "These attitudes could leave young athletes vulnerable to injury from sports-related ...

Research supports laws that require bicyclists to wear helmets

2013-05-06
WASHINGTON, DC —Bicycle helmets save lives, and their use should be required by law. That's the conclusion of a study to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. "This study highlights the importance of regulations in the promotion of safe exercise," said lead author William P. Meehan III, MD, FAAP, director of the Micheli Center for Sports Injury Prevention and the Sports Concussion Clinic at Boston Children's Hospital. About 900 people die each year in bicycle crashes, three-quarters of them from head ...

Many parents multi-task while driving kids

2013-05-06
WASHINGTON, DC – Many parents are putting their precious cargo at risk while driving, according to survey results that will be presented May 5 and 6 at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. Researchers from the University of Michigan surveyed more than 600 parents to find out what distractions they face while driving with their children, whether they use age-appropriate child restraints and if they had ever been in a motor vehicle accident. "Lots of attention has been given to distracted teen drivers. However, our results indicate ...

Foster care a sound choice for some maltreated children

2013-05-06
WASHINGTON, DC – Newspaper articles, TV shows and books are filled with horror stories of children placed in foster care. A new study bucks that trend by showing out-of-home placements can improve the emotional health of some youths who have been maltreated by a parent. The study, led by Ann-Marie Conn, PhD, general pediatric academic fellow at University of Rochester Medical Center in New York, will be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. Dr. Conn and her colleagues compared mental health problems in ...

Nearly 20 percent of suicidal youths have guns in their home

2013-05-06
WASHINGTON, DC – Nearly one in five children and teens found to be at risk for suicide report that there are guns in their homes, and 15 percent of those at risk for suicide with guns in the home know how to access both the guns and the bullets, according to a study to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. Suicide is the second leading cause of death among young people ages 10 to 24 years in the United States, according to Centers for Disease Control and Prevention data. Nearly half of youths who die by ...

Children living near toxic waste sites experience higher blood lead levels resulting in lower IQ

2013-05-06
May 6, 2013 /Press Release/ –– Children living near toxic waste sites in lower and middle income countries such as India, Philippines and Indonesia may experience higher blood lead levels, resulting in a loss of IQ points and a higher incidence of mental retardation, according to a study presented today by Kevin Chatham-Stephens, MD, Pediatric Environmental Health Fellow at the Icahn School of Medicine at Mount Sinai, at the Pediatric Academic Societies (PAS) annual meeting on May 6 in Washington, DC. The study titled, "The Pediatric Burden of Disease from Lead Exposure ...

Zeal to ensure clean leafy greens takes bite out of riverside habitat in California

2013-05-06
Meticulous attention to food safety is a good thing. As consumers, we like to hear that produce growers and distributers go above and beyond food safety mandates to ensure that healthy fresh fruits and vegetables do not carry bacteria or viruses that can make us sick. But in California's Salinas Valley, some more vigorous interventions are cutting into the last corners of wildlife habitat and potentially threatening water quality, without evidence of food safety benefits. These policies create tensions between wildlife preservation and food safety where none need exist, ...

National study of nanomaterial toxicity sets stage for policies to address health risks

2013-05-06
For the first time, researchers from institutions around the country have conducted an identical series of toxicology tests evaluating lung-related health impacts associated with widely used engineered nanomaterials (ENMs). The study provides comparable health risk data from multiple labs, which should help regulators develop policies to protect workers and consumers who come into contact with ENMs. Researchers have done a great deal of toxicological research on ENMs over the past 10 years, but the results have often been difficult to interpret. This is because ENMs from ...

Study raises concerns that teen athletes continue to play with concussion symptoms

2013-05-06
Despite knowing the risk of serious injury from playing football with a concussion, half of high school football players would continue to play if they had a headache stemming from an injury sustained on the field. In a new study, physicians from Cincinnati Children's Hospital Medical Center also report that approximately half of athletes wouldn't report concussion symptoms to a coach. The study will be presented May 6 at the annual meeting of the Pediatric Academic Societies in Washington, DC. "We aren't yet at the point where we can make specific policy recommendations ...

Summer sees a spike in chemical injuries in kids

2013-05-06
VIDEO: A new study from Nationwide Children's Hospital shows that more than 100,000 injuries were reported in children due to hydrocarbons between 2000-2009. Hydrocarbons are chemicals that are stored as liquids,... Click here for more information. (COLUMBUS, Ohio) – Hydrocarbons, a chemical compound commonly found in household items from cleaning products to gasoline, are among the top 10 causes of pediatric poisoning deaths in the United States. A new study by researchers ...

Oral drops can give kids needle-free relief from asthma, allergies

2013-05-06
Allergy shots are commonly used to treat children with severe environmental allergies and asthma, but under-the-tongue drops may offer yet another beneficial — and stick-free — option for pediatric allergy sufferers, according to a Johns Hopkins Children's Center review of existing scientific evidence. The new research comes on the heels of another recent Hopkins study, which showed that oral drops provide a safe and effective alternative for adult allergy sufferers. The new review, appearing May 6 in the journal Pediatrics, is an analysis of 34 previously published ...

Savant Books Releases Tom Donnelly/Mike Munger's New Novel, "Blessed Are the Peacekeepers"

2013-05-06
Seeking a mid-life adventure, Detective Mike Granger leaves his small city police department in New Hampshire to join the little-known United Nations Police Force. While facing armed assailants and bloody riots in war-torn Kosovo, he slowly learns the skills necessary to survive. The final test will be if he and the UN Spec-Ops team he now leads can protect a young human-trafficking victim who has been targeted for death by a brutal crime boss. Tom Donnelly has a background that includes work as a U.S. Customs officer, business intelligence analyst and trade compliance ...
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