PHILADELPHIA — With a new insight into a model of Parkinson's disease, researchers from the University of Pennsylvania School of Veterinary Medicine have identified a novel target for mitigating some of the disease's toll on the brain. Narayan G. Avadhani, Harriet Ellison Woodward Professor of Biochemistry and chair of the Department of Animal Biology at Penn Vet, was the senior author on the research. Other department members contributing to the work included Prachi Bajpai, Michelle C. Sangar, Shilpee Singh, Weigang Tang, Seema Bansal and Ji-Kang Fang. Co-authors from ...

NASA's next Small Explorer (SMEX) mission to study the little-understood lower levels of the sun's atmosphere has been fully integrated and final testing is underway. Scheduled to launch in April 2013, the Interface Region Imaging Spectrograph (IRIS) will make use of high-resolution images, data and advanced computer models to unravel how matter, light, and energy move from the sun's 6,000 K (10,240 F / 5,727 C) surface to its million K (1.8 million F / 999,700 C) outer atmosphere, the corona. Such movement ultimately heats the sun's atmosphere to temperatures much hotter ...

A new view of a 20,000-year old supernova remnant demonstrates the upgraded imaging power of the National Science Foundation's (NSF) Karl G. Jansky Very Large Array (VLA) and provides more clues to the history of this giant cloud that resembles a beloved endangered species, the Florida Manatee. W50 is one of the largest supernova remnants ever viewed by the VLA. At nearly 700 light years across, it covers two degrees on the sky – that's the span of four full Moons! Turbulent History The enormous W50 cloud formed when a giant star, 18,000 light years away in the constellation ...

Employee versus independent contractor Most small business owners want to expand their businesses. With expansion comes the need for additional help. Before doing so, however, business owners need to understand the difference between an employee and independent contractor. There can be significant legal consequences for misclassifying workers as independent contractors when they are really employees. What is an independent contractor? Independent contractors, sometimes referred to as a freelancers or consultants, are self-employed. They are hired by a business ...

Women sue National Basketball Association over gender discrimination In the fall of 2012, three women filed suit against the National Basketball Association, or NBA, and its subsidiaries NBA Entertainment and NBA Properties for gender discrimination. The women claim that the NBA changed their work schedules to make it impossible for them to continue to work with the company due to child care concerns. Lawsuit claims NBA forced working mothers to resign The women worked for a print group in a creative division of the NBA. In their lawsuit, the plaintiffs claim that ...

Discharging tax debts through bankruptcy In many cases, people who are overwhelmed by unmanageable income tax debts are able find relief by filing for bankruptcy. However, not all tax debt can be discharged in bankruptcy. It is important to understand the basic requirements when weighing the options for dealing with tax debts. Other debt relief solutions may be available for those whose tax debts do not qualify for discharge in bankruptcy. When can tax debt be discharged in bankruptcy? Even if a person has other debts that qualify for discharge during bankruptcy, ...

Sex crime detection software and your privacy When people log onto the popular social networking site Facebook, they expect that their conversations are only read by those given permission through their privacy settings. However, an anonymous, automated presence constantly trolls Facebook accounts, hunting for inappropriate language and the sharing of personal contact information. This presence is Facebook's sophisticated software created to identify and block people who appear to be soliciting sex online. Some believe its implementation goes too far and violates ...

Pennsylvania enhancing enforcement of DUI-Ds Pennsylvania police officers are targeting drivers who are driving under the influence of drugs and substances other than alcohol. Driving under the influence of drugs does not just include illegal drugs; instead, prescription drugs and certain medicines obtained over the counter can also cause driver impairment and thereby fall under the DUI statute. Many Pennsylvania DUIs involve more than just alcohol According to a Moon Township police officer, the department believes that about half of the drivers charged with DUIs ...

Georgia's implied consent law: what it means for you If you are pulled over for driving under the influence (DUI) in Georgia, you may be asked to submit to a blood, breath or urine test. You may wonder if you have to submit to the test or if you can refuse. The answer to these questions lies in Georgia's implied consent law. Requirements of the law Under Georgia's implied consent law, in exchange for the privilege of operating a motor vehicle on the state's roadways, the driver is legally deemed to have consented to take a chemical test of his or her blood, breath, ...

A city official's resignation and the gravity of a DUI in Colorado Recently, a Larimer County deputy clerk was pulled over on suspected drinking and driving. The deputy clerk -- a former Fort Collins city councilman -- has not yet pled to the charge in court but has already given the city notice of his resignation. When asked about the incident, he simply stated, "Stuff happens," but otherwise remained quiet about the situation. The city official's nearly-immediate resignation, however, demonstrates the gravity of a driving under the influence offense. A ...

Study connects bedsores to increased patient mortality, hospitalization According to a recent study by the UCLA School of Nursing, there is a direct correlation between pressure ulcers (commonly called bedsores) and patient deaths or increases in the length of hospitalization. During the study, researchers tracked approximately 51,000 hospitalized Medicare beneficiaries across the nation who were randomly selected. The study found that about 4.5 per cent of the patients developed a bedsore during their stay in the hospital. Most of the bedsores developed on the sacrum ...

Missouri drivers not immune from problem of distracted driving Twenty years ago, the idea that everyone would have a cellphone would seem like a stretch. However, the age of ubiquitous mobile devices is upon us. For all of the convenience and good that mobile technology has brought us, it has also brought a new danger that plagues roadways both in Missouri and nationwide--distracted driving. When you have driven down the road, you may have noticed drivers performing odd tasks while behind the wheel such as text messaging, talking on the phone or putting on makeup--all ...

Helping children in Texas through divorce Divorcing Texas parents must help their children adjust to a new life. Experts have suggestions for supporting children during and beyond what is likely to be a major upheaval in their lives. Talking with children Regardless of the child's age, some basic principles always apply: tell the truth, keep it simple and avoid bad-mouthing or blaming the other parent. Children want to know what is going on and why, but they don't need a lengthy, involved explanation. The simplest statements are the best. When explaining why ...

Financial issues related to divorce Article provided by Collier, House and Brown, PLLC Visit us at http://www.joydaviscollier.com Tennessee couples going through divorce are experiencing changes on many levels, not the least of which is financial. Managing finances during and beyond divorce is a challenging enterprise, and the pitfalls can be devastating for those who do not become informed and take appropriate action. Here are just a few financial concerns to watch out for. Joint obligations One major mistaken belief is that when one spouse has been ordered by ...

Antitrust concerns with Accountable Care Organizations The new Patient Protection and Affordable Care Act that was passed by Congress and President Obama provides for the creation of Accountable Care Organizations, or ACOs. An ACO is a group of medical professionals, including doctors and hospitals, who voluntarily come together to give high quality health care to Medicare patients. The goal of the ACO is to provide high quality patient care at a lower cost. Experts in the health care industry have raised concerns about the antitrust implications of ACOs; specifically, ...

New Jersey Supreme Court rules on surrogate parent law Couples struggling with infertility have several possible options; recently, surrogacy has become more a prevalent choice. In 2010, 1,488 children in the United States were born to surrogates--that is almost double the rate in 2004. With the increased use of surrogacy, many states are concerned about their laws regarding parental rights and surrogacy. The New Jersey Supreme Court recently upheld New Jersey's current and controversial surrogate parentage law. Controversy over New Jersey's surrogacy laws In ...

New Jersey is ready to update employee privacy rights The New Jersey Senate has approved a bill that protects the social media privacy rights of employees, job applicants and college students in the state. The bill is one measure to keep privacy rights up-to-date with new technology that is increasingly integrating work and personal lives. New Jersey may enact new worker privacy laws This past October, the New Jersey Senate unanimously passed two New Jersey Assembly bills that protect the privacy rights of job applicants, employees and college students. Violating ...

Despite myth, Nevada does not give child custody preference to mothers A common misconception about divorce cases in Nevada is that the law gives preference to mothers when deciding child custody matters. This is not true. If the parents cannot agree on custody matters themselves during the divorce process with which the judge approves, then the judge must decide custody based on the best interests of the child regardless of the gender of the parent given custody. However, though there is no law granting preference, many people do perceive a gender bias in the system. ...

What is carpal tunnel syndrome? Carpal tunnel syndrome is a kind of repetitive stress injury that occurs when the median nerve in the hand, which runs from the palm of a hand through the carpal tunnel in the wrist and connects the forearm to the palm, is compressed by any of the nine long flexor tendons that also pass through the carpel tunnel either swell or start to degenerate. This can be extremely painful, with patients who suffer from this condition experiencing tingling, burning and itching in the hand and fingers for extended periods of time. Workers who ...

Financial tips for divorce when children are involved Getting a divorce is challenging on multiple levels, and it can be especially difficult financially. The divorce process necessitates making determinations about how assets will be divided, and, if there are children involved, how to pay for their needs while managing two separate households. Maintaining a standard of living for children Often, parents hope to maintain the standard of living their children were accustomed to before the divorce. While doing so may be helpful for the children, it can be difficult ...

Study finds fewer medication errors when pharmacists in emergency room Most patients who are admitted into the emergency room do not come to the hospital with a detailed list of the medications they are taking at the time. For obvious reasons, it can be challenging to obtain accurate information regarding medications from people who are in need of emergency medical care. Nevertheless, accurate medication information is typically critical for physicians to provide the best possible care for the patient. In many cases, if a doctor fails to obtain enough information regarding ...

Pursuing wrongful death claims in North Carolina For any family, the death of a loved one is a considerable burden to bear. However, when that death was caused by an act of negligence -- like a car accident, nursing home neglect or the failure to diagnose a fatal medical condition -- the family's grief is frequently compounded by a sense of tragic injustice. When fatal accidents happen, North Carolina law allows the victim's survivors to pursue wrongful death lawsuits on behalf of their deceased loved one. Wrongful death claims serve the dual purpose of seeking justice ...

Women everywhere are growing tired of beauty products and advice that just don't work. Gimmicky, all-natural cures, and products full of chemicals that damage skin leave women looking for a better solution. Say hello to JiaPin Beauty, a new oriental lifestyle brand with a unique skincare line. With the launch of their new website, JiaPin Beauty aims to provide oriental health and beauty advice, seasonal recipes, well balanced products, and ingredient information right to any woman's home. JiaPin Beauty products are formulated using only effective, active ingredients. ...

MailXaminer can be the best choice of forensic investigators because of the multi talent it shows in revealing forensic evidence case studies executing analyze email evidence process. The particular enterprise forensic software helps cyber crime experts to analyze evidence collected in form of emails. The peculiarities of the software MailXaminer ( http://www.mailxaminer.com/) is many and some among them are: * Help for forensic evidence case studies by examining emails and disclosing the entire details of the email including email header, email sent receiving details ...

When a historically sensitive building was going to be turned into one of the areas many fine wineries, Craftsman Construction was brought in to Design & Build this project. The building consisted of a old dairy barn and silo located on the old army base in Vint Hill VA. The old barn had been converted into a listening post during the war. Here men and women would listen for enemy radio traffic and try to break the enemies codes. The building was very important to the war effort and old photos of the building show it surrounded by Barb Wire fencing and patrolling MP's After ...