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Penn engineers enable 'bulk' silicon to emit visible light for the first time

2013-03-27
Electronic computing speeds are brushing up against limits imposed by the laws of physics. Photonic computing, where photons replace comparatively slow electrons in representing information, could surpass those limitations, but the components of such computers require semiconductors that can emit light. Now, research from the University of Pennsylvania has enabled "bulk" silicon to emit broad-spectrum, visible light for the first time, opening the possibility of using the element in devices that have both electronic and photonic components. The research was ...

Hot flashes? Active days bring better nights

2013-03-27
CLEVELAND, Ohio (March 27, 2013)—Getting a good night's sleep isn't always easy for women at menopause. Exercise may help, but women can have a tough time carving out leisure time for it. The good news from a study published online today in Menopause, the journal of the North American Menopause Society, is that higher levels of routine daily physical activity may be the more important key to a better night's sleep for many women who have hot flashes or night sweats. Although exercise is known to improve sleep for people in general, studies in menopausal women haven't ...

Telling tales can be a good thing

2013-03-27
The act of talking is not an area where ability is usually considered along gender lines. However, a new study published in Springer's journal Sex Roles has found subtle differences between the sexes in their story-relating ability and specifically the act of reminiscing. The research by Widaad Zaman from the University of Central Florida and her colleague Robyn Fivush from Emory University in Atlanta, Georgia, discusses how these gender differences in parents can affect children's emotional development. Previous research in this area has concluded that the act of parents ...

New test for skin sensitization without using animals

2013-03-27
In an advance in efforts to reduce the use of animals in testing new cosmetic and other product ingredients for skin allergies, scientists are describing a new, highly accurate non-animal test for these skin-sensitizers. Their study appears in ACS' journal Chemical Research in Toxicology. Bruno Miguel Neves and colleagues explain that concerns about the ethics and costs of animal-based tests for skin sensitizers, plus regulations in the European Union, are fostering a search for alternative tests. Testing product ingredients prior to marketing is important, because allergic ...

Environmental enrichment important factor impacting cell transplantation and brain repair

2013-03-27
Putnam Valley, NY. (March. 27, 2013) – A team of Korean researchers investigated whether "environmental enrichment" can improve the neurobehavioral function of six week-old mice after transplantation of adipose-derived stem cells (ASCs) to treat hypoxic-ischemic brain injury, and found that brain repair (neurogenesis) was aided in some animals through exercise-induced fibroblast growth factor 2 (FGF2), a strong pro-angiogenic factor. The post-transplantation environmental enrichment (EE) included use of a running wheel and exposure to "novel objects." The study ...

Forced methadone withdrawal in jails creates barrier to treatment in community

2013-03-27
PROVIDENCE, R.I. – Methadone treatment for opioid dependence remains widely unavailable behind bars in the United States, and many inmates are forced to discontinue this evidence-based therapy, which lessens painful withdrawal symptoms. Now a new study by researchers from the Center for Prisoner Health and Human Rights, a collaboration of The Miriam Hospital and Brown University, offers some insight on the consequences of these mandatory withdrawal policies. According to their research, published online by the Journal of Substance Abuse Treatment and appearing in the ...

Ultrafine particles raise concerns about improved cookstoves

2013-03-27
A new study raises concerns about possible health impacts of very small particles of soot released from the "improved cookstoves" that international aid agencies are promoting to replace open-fire cooking in developing countries. It appears in the ACS journal Environmental Science & Technology. Brian Just and colleagues point out that 3 billion people worldwide still cook meals on stoves or open fires that burn wood, animal dung or other biomass fuel. These fires, which sometimes are indoors, release air pollutants linked to 3.5 million deaths annually. Soot, or so-called ...

Stressful life events may increase stillbirth risk, NIH network study finds

2013-03-27
Pregnant women who experienced financial, emotional, or other personal stress in the year before their delivery had an increased chance of having a stillbirth, say researchers who conducted a National Institutes of Health network study. Stillbirth is the death of a fetus at 20 or more weeks of pregnancy. According to the National Center for Health Statistics, in 2006, there was one stillbirth for every 167 births. The researchers asked more than 2,000 women a series of questions, including whether they had lost a job or had a loved one in the hospital in the year before ...

Summer melt season is getting longer on the Antarctic Peninsula, new research shows.

2013-03-27
The Antarctic Peninsula – a mountainous region extending northwards towards South America – is warming much faster than the rest of Antarctica. Temperatures have risen by up to 3 oC since the 1950s – three times more than the global average. This is a result of a strengthening of local westerly winds, causing warmer air from the sea to be pushed up and over the peninsula. In contrast to much of the rest of Antarctica, summer temperatures are high enough for snow to melt. This summer melting may have important effects. Meltwater may enlarge cracks in floating ice shelves ...

Riding the exosome shuttle from neuron to muscle

2013-03-27
WORCESTER, MA – Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting discovery that means these tiny vehicles could one day be loaded with therapeutic agents, such as RNA interference (RNAi), and directly target disease-carrying cells. The study, published this month in the journal Neuron, is the first evidence that exosomes can transfer membrane proteins that play an important role in cell-to-cell signaling in the nervous system. "There ...

HIV sufferers need hepatitis safeguards

2013-03-27
Stronger protections are needed to prevent people with HIV from also becoming infected with hepatitis, researchers argue in a new study led by Michigan State University. Behaviors that put people at higher risk of contracting HIV – sharing needles, having unprotected sex or getting blood transfusions, for instance – also raise their risk of getting hepatitis B or C, diseases that attack the liver and, if untreated, can be deadly. The study, which included all registered cases of HIV in Michigan, found about four percent of HIV-positive people also had hepatitis. That's ...

New type of solar structure cools buildings in full sunlight

2013-03-27
Homes and buildings chilled without air conditioners. Car interiors that don't heat up in the summer sun. Tapping the frigid expanses of outer space to cool the planet. Science fiction, you say? Well, maybe not any more. A team of researchers at Stanford has designed an entirely new form of cooling structure that cools even when the sun is shining. Such a structure could vastly improve the daylight cooling of buildings, cars and other structures by reflecting sunlight back into the chilly vacuum of space. Their paper describing the device was published March 5 in Nano ...

How hard is it to 'de-anonymize' cellphone data?

2013-03-27
CAMBRIDGE, MA -- The proliferation of sensor-studded cellphones could lead to a wealth of data with socially useful applications — in urban planning, epidemiology, operations research and emergency preparedness, among other things. Of course, before being released to researchers, the data would have to be stripped of identifying information. But how hard could it be to protect the identity of one unnamed cellphone user in a data set of hundreds of thousands or even millions? According to a paper appearing this week in Scientific Reports, harder than you might think. Researchers ...

An international study identifies new DNA variants that increase the risk for cancer

2013-03-27
The European Collaborative Oncological Gen-Environmental Study (COGS) project, whose main goal is to decipher the complex genetic bases of breast, prostate and ovarian cancers, publishes today a total of 12 research articles in several prestigious journals, including Nature Genetics, Nature Communications, The American Journal of Human Genetics and PLOS Genetics. Using mass sequencing techniques, the study has identified up to 80 new regions of the genome associated with an increased susceptibility to developing breast, prostate and ovarian cancers. The conclusions are ...

New system to restore wetlands could reduce massive floods, aid crops

2013-03-27
CORVALLIS, Ore. – Engineers at Oregon State University have developed a new interactive system to create networks of small wetlands in Midwest farmlands, which could help the region prevent massive spring floods and also retain water and mitigate droughts in a warming climate. The planning tool, which is being developed and tested in a crop-dominated watershed near Indianapolis, is designed to identify the small areas best suited to wetland development, optimize their location and size, and restore a significant portion of the region's historic water storage ability by ...

New insights into how genes turn on and off

2013-03-27
(SACRAMENTO, Calif.) — Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed. Working with placentas, the team discovered that 37 percent of the placental genome has regions of lower methylation, called partially methylated domains (PMDs), in which gene expression is turned off. This differs from most human tissues, in which 70 percent of the genome is highly methylated. While PMDs have been identified in cell lines, this is the first time they have been found in ...

Just 'weight' until menopause

2013-03-27
This press release is available in French. Montreal, March 27, 2013 – Women tend to carry excess fat in their hips and thighs, while men tend to carry it on their stomachs. But after menopause, things start to change: many women's fat storage patterns start to resemble those of men. This indicates that there's a link between estrogen and body fat storage. This connection is well documented, but the underlying mechanisms remained poorly understood until now. New research conducted by Sylvia Santosa, assistant professor in Concordia University's Department of Exercise ...

Understanding Earth processes and human impacts, plus another look at Mars

2013-03-27
Boulder, Colo., USA - New Geology articles cover using the architecture of ancient lava-fed deltas to estimate paleo-water levels and past ice thicknesses; bubbles and bubble haloes in lava; iron-silicate microgranules; the importance of durable, biomineralized hard parts; the link between wastewater disposal and earthquakes; shells, ocean pH, and atmospheric CO2; a SWEET hypothesis for mound-building on Mars; marine oxygenation may have preceded oxygenation on land; analysis of fossil plant tissues from Pakistan; and imaging the Transition fault. Detailed highlights ...

Do intellectual property rights on existing technologies hinder subsequent innovation?

2013-03-27
A recent study published in the Journal of Political Economy suggests that some types of intellectual property rights discourage subsequent scientific research. "The goal of intellectual property rights – such as the patent system – is to provide incentives for the development of new technologies. However, in recent years many have expressed concerns that patents may be impeding innovation if patents on existing technologies hinder subsequent innovation," said Heidi Williams, author of the study. "We currently have very little empirical evidence on whether this is ...

Why sticking around is sometimes the better choice for males

2013-03-27
Researchers from Lund University and the University of Oxford have been able to provide one answer as to why males in many species still provide paternal care, even when their offspring may not belong to them. The study finds that, when the conditions are right, sticking around despite being 'cuckolded' actually turns out to be the most successful evolutionary strategy. The study, by Charlie Cornwallis and colleagues, is published 26 March in the open access journal PLOS Biology. In many species, males put a lot of effort into caring for offspring that are not their ...

Researchers discover how model organism Tetrahymena plays roulette with 7 sexes

2013-03-27
It's been more than fifty years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined; now they do. The new findings are published 26 March in the open access journal PLOS Biology. By identifying Tetrahymena's long-unknown mating-type genes, a team of UC Santa Barbara biologists, with research colleagues in the Institute of Hydrobiology of the Chinese Academy of Sciences, and in the J. Craig Venter Institute, also uncovered the ...

Certified stroke centers more likely to give clot-busting drugs

2013-03-27
Stroke patients are three times more likely to receive clot-busting medication if treated at a certified stroke center, according to a study in the Journal of the American Heart Association. Intravenous tissue plasminogen activator (tPA) is the only drug approved by the Food and Drug Administration for emergency treatment for people who have ischemic (clot-caused) stroke. The durg can reduce stroke disability. "The stroke center concept has rapidly taken off, and this data demonstrates one way that certified centers are doing better than non-certified centers," said Michael ...

Chelation therapy may result in small reduction of risk of CV events

2013-03-27
Although chelation therapy with the drug disodium EDTA has been used for many years with limited evidence of efficacy for the treatment of coronary disease, a randomized trial that included patients with a prior heart attack found that use of a chelation regimen modestly reduced the risk of a composite of adverse cardiovascular outcomes, but the findings do not support the routine use of chelation therapy for treatment of patients who have had a heart attack, according to a study in the March 27 issue of JAMA. Chelation therapy is an intravenous administration of chelating ...

Azithromycin may provide benefit for treatment of respiratory disorder

2013-03-27
Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA. Bronchiectasis is characterized by abnormal widening of the bronchi (air tubes that branch deep into the lungs) and can cause recurrent lung infections, a disabling cough, shortness of breath, and coughing up blood. "If progressive, this process may lead to respiratory failure and the need for lung transplantation ...

Antibiotic may provide benefit for treatment of respiratory disorder

2013-03-27
Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic erythromycin resulted in improvement in symptoms but also increased the risk of antibiotic resistance, according to a study appearing in the March 27 issue of JAMA. David J. Serisier, M.B.B.S., D.M., F.R.A.C.P., of Mater Adult Hospital, South Brisbane, Australia, and colleagues tested the hypothesis that low-dose erythromycin would reduce pulmonary exacerbations in patients with non-CF bronchiectasis with a history of frequent exacerbations. The study consisted of ...
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