PORTLAND, Ore. − Patients with two forms of leukemia, who currently have no viable treatment options, may benefit from existing drugs developed for different types of cancer, according to a study conducted by researchers at the Knight Cancer Institute at Oregon Health & Science University (OHSU). The study, published in the May 9 edition of the New England Journal of Medicine, isolated the molecular mutation that causes chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) in some patients. That mutation, occurring in a gene called colony ...

Sunless tanning — whether with lotions, bronzers or tanning pills — has been promoted as an effective substitute to dodge the health risks of ultraviolet rays, but if the products don't provide the perfect tan, young women likely will not use them, according to a Baylor University researcher. "The feeling is 'I tan, I feel good, I'll look good tomorrow . . . What's health?'" said Jay Yoo, Ph.D., an assistant professor of family and consumer sciences in Baylor's College of Arts & Sciences. He conducted a study of 182 Caucasian female college students, with an average age ...

A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division -- the hallmark of the disease -- it also can help make cells more fit by allowing them to fend off stress, says a University of Colorado Boulder study. CU-Boulder Professor Min Han said the research team was interested in how a common tumor suppressor gene known as Retinoblastoma 1, or Rb, behaved under conditions of starvation. The question is important, said Han, because it may help researchers understand why many cancer cells are more susceptible to starvation ...

From the several pandemics generally called 'pestilences' three are historically recognized as due to plague, but only for the third pandemic of the 19th to 21st centuries AD there were microbiological evidences that the causing agent was the bacterium Yersinia pestis. "For a long time scholars from different disciplines have intensively discussed about the actual etiological agents of the past pandemics. Only ancient DNA analyses carried out on skeletal remains of plague victims could finally conclude the debate", said Dr. Barbara Bramanti of the Palaeogenetics Group at ...

A University of Southampton professor has carried out the most detailed analysis ever of the archaeological remains of the lost medieval town of Dunwich, dubbed 'Britain's Atlantis'. Funded and supported by English Heritage, and using advanced underwater imaging techniques, the project led by Professor David Sear of Geography and Environment has produced the most accurate map to date of the town's streets, boundaries and major buildings, and revealed new ruins on the seabed. Professor Sear worked with a team from the University's GeoData Institute; the National Oceanography ...

The so-called Elephant's Tomb in the Roman necropolis of Carmona (Seville, Spain) was not always used for burials. The original structure of the building and a window through which the sun shines directly in the equinoxes suggest that it was a temple of Mithraism, an unofficial religion in the Roman Empire. The position of Taurus and Scorpio during the equinoxes gives force to the theory. The Carmona necropolis (Spain) is a collection of funeral structures from between the 1st century B.C. and the 2nd century A.D. One of these is known as the Elephant's Tomb because a ...

Researchers from IMDEA-Nanociencia Institute and from Autonoma and Complutense Universities of Madrid (Spain) have managed to give graphene magnetic properties. The breakthrough, published in the journal 'Nature Physics', opens the door to the development of graphene-based spintronic devices, that is, devices based on the spin or rotation of the electron, and could transform the electronics industry. Scientists were already aware that graphene, an incredible material formed of a mesh of hexagonal carbon atoms, has extraordinary conductivity, mechanical and optical properties. ...

WASHINGTON--Researchers at the U.S. Naval Research Laboratory flew their fuel cell powered Ion Tiger unmanned aerial vehicle (UAV) for 48 hours and 1 minute, April 16 to 18, by using liquid hydrogen (LH2) fuel in a new, NRL-developed, cryogenic fuel storage tank and delivery system. This flight shatters their previous record of 26 hours and 2 minutes set in 2009 using the same vehicle, but with gaseous hydrogen stored at 5,000 pounds per square inch (psi). Liquid hydrogen is three times denser than compressed hydrogen. The cryogenic liquid is stored in a lightweight tank, ...

ANN ARBOR, Mich. — When it comes to a cancer diagnosis, timing can be everything – the sooner it's found, the more treatable it is. But when and how often should someone get screened? A growing number of educational, interactive tools known as "decision aids" – such as videodiscs, audiotapes, workbooks and pamphlets – are intended to supplement patient-doctor discussions on the pros and cons of timing, methods and frequency for different types of cancer screening. A University of Michigan study found that despite strong recommendations from the medical community ...

Our ability to assess biological diversity, ecosystem health, ecological interactions, and a wide range of other important processes is largely dependent on accurately recognizing species. However, identifying and describing species is not always a straightforward task. In some cases, a single species may show a high level of morphological variation, while in other cases, multiple morphologically similar species may be hidden under a single species name. Cryptic species, two or more distinct species that are erroneously classified under a single species name, are found ...

WACO, Texas (May 9, 2013) -- A recent Baylor University research study has shed new light on the diet and food acquisition strategies of some the earliest human ancestors in Africa. Beginning around two million years ago, early stone tool-making humans, known scientifically as Oldowan hominin, started to exhibit a number of physiological and ecological adaptations that required greater daily energy expenditures, including an increase in brain and body size, heavier investment in their offspring and significant home-range expansion. Demonstrating how these early humans ...

Philadelphia, Pa. (May 10, 2013) – Exercise has been shown to be an effective treatment for major depressive disorder (MDD), both when used alone and in combination with other treatments. There's now sufficient research data to provide specific guidance on how to prescribe exercise for depressed patients, according to a report in the May Journal of Psychiatric Practice®. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. "Despite the substantial evidence supporting the use of exercise in the treatment of MDD, previous studies ...

Philadelphia, Pa. (May 10, 2013) – A new "alternative model" included in the upcoming Fifth Edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM -5) lines up well with the current approach to diagnosis of personality disorder, according to a study in the May Journal of Psychiatric Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The findings lend support to the new "hybrid" model, which combines the "core" dimensions of personality disorder with various maladaptive ...

Many people express objections against child labor, exploitation of the workforce or meat production involving cruelty against animals. At the same time, however, people ignore their own moral standards when acting as market participants, searching for the cheapest electronics, fashion or food. Thus, markets reduce moral concerns. This is the main result of an experiment conducted by economists from the Universities of Bonn and Bamberg. The results are presented in the latest issue of the renowned journal "Science". Prof. Dr. Armin Falk from the University of Bonn and ...

Quantum dots are tiny nanocrystals with extraordinary optical and electrical properties with possible uses in dye production, bioimaging, and solar energy production. Researchers at the University of Illinois at Chicago have developed a way to introduce precisely four copper ions into each and every quantum dot. The introduction of these "guest" ions, called doping, opens up possibilities for fine-tuning the optical properties of the quantum dots and producing spectacular colors. "When the crystallinity is perfect, the quantum dots do something that no one expected--they ...

Chicago (May 10, 2013): Ambient background noise—whether it is the sound of loud surgical equipment, talkative team members, or music—is a patient and surgical safety factor that can affect auditory processing among surgeons and the members of their team in the operating room (OR), according to a new study that appears in the May issue of the Journal of the American College of Surgeons. The findings are the first to demonstrate that a surgeon's ability to understand spoken words in the OR is directly affected by noise in the environment. "The operating room is a very ...

This news release is available in German. AMHERST, Mass., USA; COLOGNE, Germany; MAGADAN, Russia – Analyses of the longest continental sediment core ever collected in the Arctic, recently completed by an international team led by Julie Brigham-Grette of the University of Massachusetts Amherst, provide "absolutely new knowledge" of Arctic climate from 2.2 to 3.6 million years ago. "While existing geologic records from the Arctic contain important hints about this time period, what we are presenting is the most continuous archive of information about past ...

The DFG-Center for Regenerative Therapies Dresden - Cluster of Excellence at the TU Dresden (CRTD), the Dresden site of the German Center for Neurodegenerative Diseases (DZNE), and the Max Planck Institute for Human Development in Berlin played a pivotal role in the study. The adult brain continues to grow with the challenges that it faces; its changes are linked to the development of personality and behavior. But what is the link between individual experience and brain structure? Why do identical twins not resemble each other perfectly even when they grew up together? ...

Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have established an inheritable bacterial infection in malaria-transmitting Anopheles mosquitoes that renders them immune to malaria parasites. Specifically, the scientists infected the mosquitoes with Wolbachia, a bacterium common among insects that previously has been shown to prevent malaria-inducing Plasmodium parasites from developing in Anopheles mosquitoes. Before now, researchers had been unable to create mosquitoes with a stable Wolbachia ...

PROVIDENCE, R.I. [Brown University] —Water inside the Moon's mantle came from primitive meteorites, new research finds, the same source thought to have supplied most of the water on Earth. The findings raise new questions about the process that formed the Moon. The Moon is thought to have formed from a disc of debris left when a giant object hit the Earth 4.5 billion years ago, very early in Earth's history. Scientists have long assumed that the heat from an impact of that size would cause hydrogen and other volatile elements to boil off into space, meaning the Moon must ...

Having a pet might lower your risk of heart disease, according to a new American Heart Association scientific statement. The statement is published online in the association's journal Circulation. "Pet ownership, particularly dog ownership, is probably associated with a decreased risk of heart disease" said Glenn N. Levine, M.D., professor at Baylor College of Medicine in Houston, Texas, and chair of the committee that wrote the statement after reviewing previous studies of the influence of pets. Research shows that: Pet ownership is probably associated with a reduction ...

A team of NIH scientists has developed a new tool to identify broadly neutralizing antibodies (bNAbs) capable of preventing infection by the majority of HIV strains found around the globe, an advance that could help speed HIV vaccine research. Scientists have long studied HIV-infected individuals whose blood shows powerful neutralization activity because understanding how HIV bNAbs develop and attack the virus can yield clues for HIV vaccine design. But until now, available methods for analyzing blood samples did not easily yield specific information about the HIV bNAbs ...

Washington, D.C.— Water is perhaps the most important molecule in our solar system. Figuring out where it came from and how it was distributed within and among the planets can help scientists understand how planets formed and evolved. New research from a team including Carnegie's Erik Hauri demonstrates that water from the interiors of the Earth and Moon has a common origin. Their work is published online in Science Express. The Moon is thought to have formed from a disc of debris left when a Mars-sized impactor hit the Earth 4.5 billion years ago, the Giant Impact. ...

New research shows that growing up in areas where air pollution is increased raises the risk of insulin resistance (the prescursor to diabetes) in children. The research is published in Diabetologia, the journal of the European Association for the Study of Diabetes (EASD), and is by Elisabeth Thiering and Joachim Heinrich, Helmholtz Zentrum München, Neuherberg, Germany, and colleagues. Previous studies have identified links between air pollution and other chronic conditions such as atherosclerosis and heart disease. However to date, epidemiological studies that have ...

A large scale, five year study of mosquitoes from different ecological regions in Kenya, including savannah grassland, semi-arid Acacia thorn bushes, and mangrove swamps, found a reservoir of viruses carried by mosquitoes (arboviruses) that are responsible for human and animal diseases. This research, published in BioMed Central's open access journal Virology Journal, highlights the need for continued surveillance in order to monitor the risk of disease outbreaks. Over 450,000 mosquitoes from 11 sites across Kenya were screened by researchers from the United States Army ...