Working with an international consortium conducting research on breast, ovarian and prostate cancer among 200,000 people, Professor Jacques Simard, holder of the Canada Research Chair in Oncogenetics at Laval University, was actively involved in the discovery of DNA "spelling mistakes" linked to breast cancer. These mistakes – known as genetic variations – are directly involved in the risk of developing breast cancer. The research was part of an international study on an unprecedented scale performed by the largest international consortia, the Collaborative Oncological ...

Bonn, Germany 27 March 2013 – In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate between interconnected areas of the brain, thereby contributing to the development of the illness. Now, a new laboratory study by scientists from Germany and the US shows that certain protein particles are indeed capable of multiplying and spreading from one cell to the next. The investigation was conducted by researchers ...

For around 50 million years, placodonts populated the flat coastal regions of the Tethys Ocean, in modern day Europe and China. The most distinctive feature of these dinosaurs was their teeth: The upper jaw had two rows of flattened teeth – one on the palate and one on the jawbone – while the lower jaw only had one set of teeth ideal for crushing shellfish and crustaceans. The evolutionary origins of these placodonts remained unclear. However, a new find in a 246-million-year-old sediment layer now sheds light on the origin and phylogenetic development of the placodonts. ...

Researchers from Lund University, Yale University and the University of Oxford have been able to give an answer to why cuckolded males in many species still provide paternal care. When the conditions are right, this strategy is actually the most successful. In many species males put a lot of effort into caring for offspring that are not their own. At first glance this makes no sense at all because natural selection should design males to only care for offspring that carry their genes. However, males are much more astute than we might think and maximise their care according ...

New research into ageing processes, based on modern genetic techniques, confirms theoretical expectations about the correlation between reproduction and lifespan. Studies of birds reveal that those that have offspring later in life and have fewer broods live longer. And the decisive factor is telomeres, shows research from The University of Gothenburg, Sweden. Telomeres are the protective caps at the end of chromosomes. The length of telomeres influences how long an individual lives. Telomeres start off at a certain length, become shorter each time a cell divides, ...

This press release is available in German. Zooplankton, small fish and squid spend hardly any time at the surface when there's a full moon. To protect themselves from their natural enemies, they hide deeper down in the water on bright nights, coming up to the surface under cover of darkness when there's a new moon instead. Scientists at the Max Planck Institute for Ornithology in Radolfzell discovered that this also influences the behaviour of swallow-tailed gulls (Creagrus furcatus), a unique nocturnal species of gull from the Galapagos Islands. They fitted the ...

Philadelphia, PA, March 26, 2013 – Like it or not and despite the surrounding debate of its merits, 3-D is the technology du jour for movie-making in Hollywood. It now turns out that even our brains use 3 dimensions to communicate emotions. According to a new study published in Biological Psychiatry, the human report of emotion relies on three distinct systems: one system that directs attention to affective states ("I feel"), a second system that categorizes these states into words ("good", "bad", etc.); and a third system that relates the intensity of affective responses ...

Since its introduction fifty or so years ago, thermography has been increasingly used by vets to pinpoint the cause of lameness in horses. The method is fast and safe and is based on a simple idea. The horse's body surface emits infrared radiation that can be detected by an infrared camera, which is both easy and inexpensive to use. The camera produces a coloured image that shows the variation in surface temperature across the area investigated. The temperature is directly related to the presence of blood vessels near the skin, so the method can detect local inflammatory ...

PHILADELPHIA (March 27, 2013) -- In 370 million-year-old red sandstone deposits in a highway roadcut, scientists have discovered a new species of armored fish in north central Pennsylvania. Fossils of armored fishes like this one, a phyllolepid placoderm, are known for the distinctive ornamentation of ridges on their exterior plates. As with many such fossils, scientists often find the remains of these species as impressions in stone, not as three-dimensional versions of their skeletons. Therefore, in the process of studying and describing this fish's anatomy, scientists ...

Working with the International Tennis Federation and colleagues at the University of Exeter, the team from the University of Sheffield's Faculty of Engineering developed a test machine which applies large forces to a surface to mimic the impact of elite tennis players on tennis courts. This impact can be up to four times the bodyweight of a player. They used the machine to measure the friction on an acrylic (hard) court in dry conditions and two artificial clay court surfaces in both wet and dry conditions. The team found that on clay surfaces the size of the sand particles ...

In theory, silicon-based solar cells are capable of converting up to 30 percent of sunlight to electricity - although, in reality, the different kinds of loss mechanisms ensure that even under ideal lab conditions it does not exceed 25 %. Advanced heterojunction cells shall affront this problem: On top of the wafer's surface, at temperatures below 200 °C, a layer of 10 nanometer disordered (amorphous) silicon is deposited. This thin film is managing to saturate to a large extent the interface defects and to conduct charge carriers out of the cell. Heterojunction solar cells ...

This press release is available in Spanish. Researchers with the joint program between IRB Barcelona and the Barcelona Supercomputing Center (BSC) have devised a new strategy to study the shape of proteins. This study has been led by Modesto Orozco, head of the Molecular Modeling and Bioinformatics Group, and Xavier Salvatella, head of the Molecular Biophysics Group, both ICREA scientists at IRB Barcelona. According to Orozco, also senior professor of the University of Barcelona and director of the Life Sciences Department at BSC, "by combining computational modeling ...

A new study by University of Pennsylvania linguists shows that the Philadelphia accent has changed in the last century. The traditional Southern inflections associated with Philadelphia native-born speakers are increasingly being displaced by Northern influences. "A Hundred Years of Sound Change," published in the March issue of the journal Language, documents Philadelphia's changing accent through an analysis of speech patterns of city residents spanning more than a century. The study is co-authored by William Labov, professor of linguistics and director of Penn's ...

The level of education of parents has an influence on the frequency with which their children eat foods linked to obesity. The children of parents with low and medium levels of education eat fewer vegetables and fruit and more processed products and sweet drinks. An international group of experts from eight European countries have analysed the relation between parents' levels of education and the frequency with which their children eat food linked to overweight. The Identification and prevention of dietary- and lifestyle-induced health effects in children and infants ...

New research from the Massachusetts Eye and Ear, Harvard Medical School and Harvard Program in Speech and Hearing Bioscience and Technology may have discovered a key piece in the puzzle of how hearing works by identifying the role of the olivocochlear efferent system in protecting ears from hearing loss. The findings could eventually lead to screening tests to determine who is most susceptible to hearing loss. Their paper is published today in the Journal of Neuroscience. Until recently, it was common knowledge that exposure to a noisy environment (concert, iPod, mechanical ...

Researchers are arguing about whether or not the Xenoturbella bocki worm is the progenitor of mankind. But new studies indicate that this is actually the case. Swedish researchers from the University of Gothenburg and the Gothenburg Natural History Museum are involved in the international study. The results have been published in Nature Communications. The Xenoturbella bocki worm is a one-centimetre long worm with a simple body plan that is only found regularly by the west coast of Sweden. The worm lacks a brain, sexual organs and other vital organs. Zoologists have ...

Some people may joke about living on caffeine, but scientists now have genetically engineered E. coli bacteria to do that — literally. Their report in the journal ACS Synthetic Biology describes bacteria being "addicted" to caffeine in a way that promises practical uses ranging from decontamination of wastewater to bioproduction of medications for asthma. Jeffrey E. Barrick and colleagues note that caffeine and related chemical compounds have become important water pollutants due to widespread use in coffee, soda pop, tea, energy drinks, chocolate and certain medications. ...

Now, a group of researchers led by two astronomers at the University of Toronto suggests that baby stars may grow to great mass if they happen to be born within a corral of older stars –with these surrounding stars favorably arranged to confine and thus feed gas to the younger ones in their midst. The astronomers have seen hints of this collective feeding, or technically "convergent constructive feedback," in a giant cloud of gas and dust called Westerhout 3 (W3), located 6,500 light years from us. Their results are published in April in The Astrophysical Journal. ### ...

PHILADELPHIA (March 27, 2013)— "We call it a 'fish-eat-fish world,' an ecosystem where you really needed to escape predation," said Dr. Ted Daeschler, describing life in the Devonian period in what is now far-northern Canada. This was the environment where the famous fossil fish species Tiktaalik roseae lived 375 million years ago. This lobe-finned fish, co-discovered by Daeschler, an associate professor at Drexel University in the Department of Biodiversity, Earth and Environmental Science, and associate curator and vice president of the Academy of Natural Sciences of ...

ROCHESTER, Minn. -- Patients receiving antihistamines to suppress stomach acid are at greater risk of infection from Clostridium difficile, or C. diff, a common cause of diarrhea, particularly in health care settings, Mayo Clinic researchers have found. The study focused on histamine 2 receptor antagonists. The researchers found no significant risk for people taking over-the-counter antihistamine drugs, however. The findings appear in the online journal PLOS ONE. Researchers reviewed 35 observations based on 33 separate studies involving C. diff and antihistamines used ...

Electronic computing speeds are brushing up against limits imposed by the laws of physics. Photonic computing, where photons replace comparatively slow electrons in representing information, could surpass those limitations, but the components of such computers require semiconductors that can emit light. Now, research from the University of Pennsylvania has enabled "bulk" silicon to emit broad-spectrum, visible light for the first time, opening the possibility of using the element in devices that have both electronic and photonic components. The research was ...

CLEVELAND, Ohio (March 27, 2013)—Getting a good night's sleep isn't always easy for women at menopause. Exercise may help, but women can have a tough time carving out leisure time for it. The good news from a study published online today in Menopause, the journal of the North American Menopause Society, is that higher levels of routine daily physical activity may be the more important key to a better night's sleep for many women who have hot flashes or night sweats. Although exercise is known to improve sleep for people in general, studies in menopausal women haven't ...

The act of talking is not an area where ability is usually considered along gender lines. However, a new study published in Springer's journal Sex Roles has found subtle differences between the sexes in their story-relating ability and specifically the act of reminiscing. The research by Widaad Zaman from the University of Central Florida and her colleague Robyn Fivush from Emory University in Atlanta, Georgia, discusses how these gender differences in parents can affect children's emotional development. Previous research in this area has concluded that the act of parents ...

In an advance in efforts to reduce the use of animals in testing new cosmetic and other product ingredients for skin allergies, scientists are describing a new, highly accurate non-animal test for these skin-sensitizers. Their study appears in ACS' journal Chemical Research in Toxicology. Bruno Miguel Neves and colleagues explain that concerns about the ethics and costs of animal-based tests for skin sensitizers, plus regulations in the European Union, are fostering a search for alternative tests. Testing product ingredients prior to marketing is important, because allergic ...

Putnam Valley, NY. (March. 27, 2013) – A team of Korean researchers investigated whether "environmental enrichment" can improve the neurobehavioral function of six week-old mice after transplantation of adipose-derived stem cells (ASCs) to treat hypoxic-ischemic brain injury, and found that brain repair (neurogenesis) was aided in some animals through exercise-induced fibroblast growth factor 2 (FGF2), a strong pro-angiogenic factor. The post-transplantation environmental enrichment (EE) included use of a running wheel and exposure to "novel objects." The study ...