Metabolic biomarkers for preventive molecular medicine
2012-12-04
One of the big challenges of biomedicine is understanding the origin of illnesses in order to improve early detection and significantly increase recovery rates, as well as being able to do what CNIO researchers call preventive molecular medicine, which consists of identifying those individuals who have a greater molecular risk of suffering certain pathologies in order to prevent them. The ageing of the organism, and therefore of the cells and tissues it is made of, represents the greatest risk factor for the majority of developed-world illnesses, including cancer.
A team ...
Carnegie debuts revolutionary biosphere mapping capability at AGU
2012-12-04
San Francisco, CA —Researchers from the Carnegie Institution are rolling out results from the new Airborne Taxonomic Mapping System, or AToMS, for the first time at the American Geophysical Union (AGU) meetings in San Francisco. The groundbreaking technology and its scientific observations are uncovering a previously invisible ecological world. To watch a video about how AToMS is helping researchers look at the world in a whole new way, click here.
AToMS, which launched in June 2011, uniquely combines laser and spectral imaging instrumentation onboard a twin-engine aircraft ...
African savannah -- and its lions -- declining at alarming rates
2012-12-04
DURHAM, NC -- About 75 percent of Africa's savannahs and more than two-thirds of the lion population once estimated to live there have disappeared in the last 50 years, according to a study published this week in the journal Biodiversity and Conservation.
The study, led by Duke University researchers, estimates the number of lions now living on the savannahs to be as low as 32,000, down from nearly 100,000 in 1960. Lion populations in West Africa have experienced the greatest declines.
"The word savannah conjures up visions of vast open plains teeming with wildlife. ...
Driverless vehicles expected to navigate intersection of safety, speed
2012-12-04
How do driverless vehicles navigate through intersections? Faster and safer than if humans were in charge, according to researchers with the Virginia Tech Transportation Institute.
Autonomous vehicles will turn themselves over to an automated intersection controller, which adjusts the trajectory and speed of the vehicles to prevent crashes, said Ismail Zohdy of Cairo, Egypt, a Ph.D. student in civil engineering at Virginia Tech, and Hesham Rakha, director of the Center for Sustainable Mobility at the transportation institute and professor of civil engineering at the university. ...
New method for creating long-lived stem cells used for bone replacement
2012-12-04
New Rochelle, NY, December 4, 2012—Human mesenchymal stem cells (hMSCs) can develop into bone cells and are useful for tissue engineering and regeneration. However, when grown in the laboratory they quickly lose their ability to continue dividing and they die. A method for genetically engineering hMSCs so they become immortal and still retain their ability to become bone cells is described in an article published in BioResearch Open Access, a bimonthly peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access ...
Nanotechnology drug delivery shows promise for treatment of pediatric cancer
2012-12-04
Wilmington, DE – This month, Molecular Pharmaceutics reported promising findings from the Nemours Center for Childhood Cancer Research and the Materials Science and Engineering Department at the University of Delaware, about the potential for nanotechnology to deliver chemotherapeutic agents in a way that attacks cancer cells without harming healthy cells. To date, nanoparticle-based drug delivery approaches have been poorly developed for the treatment of childhood leukemia, which comprises 30% of childhood cancers. In the Nemours study, encapsulated dexamethasone ("dex") ...
Study finds prioritizing rather than canvassing entire plant genome may lead to improved crops
2012-12-04
MANHATTAN, Kan. -- A new study may help scientists produce better climate-resistant corn and other food production plants by putting a spin on the notion that we are what we eat.
Kansas State University geneticists and colleagues found that by applying a genetic-analysis method used to study and prioritize the genes in humans, it improved the likelihood of finding critical genes in food production plants. These genes control quantitate traits in plants, such as how the plants grow and when they flower.
Additionally, this method can be used to study how food production ...
Emergency physician's loss sparks advocacy
2012-12-04
Boston – Jonathan Welch, MD, a physician in the Department of Emergency Medicine at Brigham and Women's Hospital, never thought his family would be part of a medical error. But when his mother's battle with cancer took a sudden turn and she was rushed to a community hospital in Wisconsin, Welch watched in helpless horror as a series of mistakes lead to her death. After the funeral, he encouraged the Wisconsin hospital's administrators to make changes to avoid future errors and deaths, but his experience proved frustrating and fruitless. Now, in an essay that appears ...
Study: Parents key to preventing alcohol, marijuana use by kids
2012-12-04
New research from North Carolina State University, Brigham Young University and the Pennsylvania State University finds that parental involvement is more important than the school environment when it comes to preventing or limiting alcohol and marijuana use by children.
"Parents play an important role in shaping the decisions their children make when it comes to alcohol and marijuana," says Dr. Toby Parcel, a professor of sociology at NC State and co-author of a paper on the work. "To be clear, school programs that address alcohol and marijuana use are definitely valuable, ...
Working towards happiness
2012-12-04
Raising the retirement age to increase financial stability does not make men worse off psychologically in the long-run, according to a new study by Dr. Elizabeth Mokyr Horner, from the University of California, Berkeley in the US. Her work shows that individuals go through the same psychological stages as they adjust to retirement, with life satisfaction stabilizing after 70, irrespective of how old they are when they retire. The study is published online in Springer's Journal of Happiness Studies.
As we live longer, the size of the retired population relative to that ...
A bridge to the quantum world: Dirac electrons found in unique material
2012-12-04
ANN ARBOR—In a discovery that helps clear a new path toward quantum computers, University of Michigan physicists have found elusive Dirac electrons in a superconducting material.
Quantum computers use atoms themselves to perform processing and memory tasks. They promise dramatic increases in computing power because of their ability to carry out scores of calculations at once. They could factor numbers dramatically faster than conventional computers, and would be game-changers for computer security.
The combination of properties the researchers identified in a shiny, ...
Predicting the age at menopause of women having suffered from childhood cancers
2012-12-04
This press release is available in French. This study provided important data about the fertility window of women who had suffered from childhood cancer and information concerning the associated risk factors, but did not confirm the greater risk of premature menopause (before the age of 40) that was reported by the American studies.
The results were published in the review Human Reproduction of November 15.
Women who have suffered from childhood cancer are known to run a greater risk of premature menopause. However, data about the associated risk factors is limited. ...
Multiple media use tied to depression, anxiety
2012-12-04
EAST LANSING, Mich. — Using multiple forms of media at the same time – such as playing a computer game while watching TV – is linked to symptoms of anxiety and depression, scientists have found for the first time.
Michigan State University's Mark Becker, lead investigator on the study, said he was surprised to find such a clear association between media multitasking and mental health problems. What's not yet clear is the cause.
"We don't know whether the media multitasking is causing symptoms of depression and social anxiety, or if it's that people who are depressed ...
Research shows immune system response is detrimental to novel brain cancer therapy
2012-12-04
Boston -- For the first time, researchers have demonstrated that the response of natural killer (NK) cells is detrimental to glioblastoma virotherapy, a novel way of treating malignant brain cancer by injecting a virus into the tumor. A number of clinical trials are currently underway to test whether glioblastoma virotherapy will facilitate antitumor efficacy, but research led by E. Antonio Chiocca, MD, PhD, chairman of the Department of Neurosurgery at Brigham and Women's Hospital, and published in Nature Medicine, shows that in pre-clinical models, NK cells are killing ...
The radical restructuring of brain networks in comatose patients
2012-12-04
This press release is available in French.The researchers are focusing on analysing brain networks of brain-damaged comatose (non-traumatised) patients, a state where the individual is considered to be unconscious.
The authors of the study used an original graph theory-based methodology, where images were constructed using functional MRI data at rest and using robust statistical signal-processing methods. Local and overall effectiveness indices of functional brain networks were obtained for 17 brain-damaged patients and 20 healthy volunteers. Correlations in 417 brain ...
Nature Materials study: Boosting heat transfer with nanoglue
2012-12-04
Troy, N.Y. – A team of interdisciplinary researchers at Rensselaer Polytechnic Institute has developed a new method for significantly increasing the heat transfer rate across two different materials. Results of the team's study, published in the journal Nature Materials, could enable new advances in cooling computer chips and lighting-emitting diode (LED) devices, collecting solar power, harvesting waste heat, and other applications.
By sandwiching a layer of ultrathin "nanoglue" between copper and silica, the research team demonstrated a four-fold increase in thermal ...
Fish oil helps heal bed sores of the critically ill
2012-12-04
Chock-full of Omega-3 fatty acids and antioxidants, fish oil can help lower blood pressure, reduce inflammation in the skin and joints, and promote healthy fetal development. Now a Tel Aviv University researcher has found that it has a positive effect on bedsores, too.
A common problem in critically ill patients, bedsores result from constant pressure on the skin and underlying tissue due to prolonged sitting or lying down. Painful and prone to infection, the pressure ulcers need to be healed, says Prof. Pierre Singer of the Sackler Faculty of Medicine. With Ph.D. candidate ...
Understanding anger, overcoming anxiety
2012-12-04
Montreal, December 4, 2012 – Anger is a powerful emotion with serious health consequences. A new study from Concordia University shows that for millions of individuals around the world who suffer from Generalized Anxiety Disorder (GAD), anger is more than an emotion; it's an agent that exacerbates their illness.
Concordia graduate student Sonya Deschênes investigated the subject after conducting a literature review for her PhD research, supervised by psychology professor Michel Dugas. While some of the studies she came across showed that anger and anxiety were linked, ...
Sunshine, biofuel and the tides, oh my!
2012-12-04
SAN FRANCISCO - Scientists from the Department of Energy's Pacific Northwest National Laboratory will present a variety of alternative energy-related research at the 2012 American Geophysical Union Fall Meeting, which runs Monday, Dec. 3 through Friday, Dec. 7 at the Moscone Convention Center in San Francisco. Topics to be discussed include improving solar power forecasting, measuring the resources needed to grow algae for biofuel and predicting the environmental impacts of ocean energy. Summaries of some of PNNL's noteworthy presentations are below.
Forecasting clouds ...
Herschel and Keck take census of the invisible Universe
2012-12-04
By combining the observing powers of ESA's Herschel space observatory and the ground-based Keck telescopes, astronomers have characterised hundreds of previously unseen starburst galaxies, revealing extraordinary high star-formation rates across the history of the Universe.
Starburst galaxies give birth to hundreds of solar masses' worth of stars each year in short-lived but intense events.
By comparison, our own Milky Way Galaxy on average produces the equivalent of only one Sun-like star per year.
Starburst galaxies generate so much starlight that they should outshine ...
Overprescribing of opioids impacts patient safety and public health
2012-12-04
A Viewpoint article published recently in the Journal of the American Medical Association suggests that the clinical practice of prescribing amphetamines, opioids, and benzodiazepines to treat chronic pain may be contributing to the increase in fatal drug overdoses and the likelihood that those drugs will be diverted to the illegal market. "Rethinking Opioid Prescribing to Protect Patient Safety and Public Health" was authored by Johns Hopkins Bloomberg School of Public Health researchers G. Caleb Alexander, MD, MS, and Daniel Webster, ScD, MPH, and Stefan P. Kruszewski, ...
Targeting neurotransmitter may help treat gastrointestinal conditions
2012-12-04
HERSHEY, Pa. -- Selective targeting of the neurotransmitter that differentially affects brain cells that control the two distinct functions of the pancreas may allow for new medication therapies for conditions like diabetes, dyspepsia and gastro-esophageal reflux, according to Penn State College of Medicine researchers.
"This study differs from what's been reported previously about brain neurons that control the gastrointestinal tract," said R. Alberto Travagli, professor, Department of Neural and Behavioral Sciences, and lead investigator. "It provides further support ...
Telecommuting increases work hours and blurs boundary between work and home, new study shows
2012-12-04
AUSTIN, Texas — With fluctuating gas prices and the increasing call for work-life balance, telecommuting has become an attractive option for busy professionals. Yet according to a new study from The University of Texas at Austin, for most employees who work remotely, telecommuting equates to working more hours.
The study, co-authored by Jennifer Glass, professor in the Department of Sociology and the Population Research Center, shows that most of the 30 percent of respondents who work from home add five to seven hours to their workweek compared with those who work exclusively ...
Infants learn to look and look to learn
2012-12-04
Researchers at the University of Iowa have documented an activity by infants that begins nearly from birth: They learn by taking inventory of the things they see.
In a new paper, the psychologists contend that infants create knowledge by looking at and learning about their surroundings. The activities should be viewed as intertwined, rather than considered separately, to fully appreciate how infants gain knowledge and how that knowledge is seared into memory.
"The link between looking and learning is much more intricate than what people have assumed," says John Spencer, ...
Improving chemotherapy effectiveness by acting on the immune system
2012-12-04
This press release is available in French. These results reveal how the immune system can then limit the effectiveness of some cancer chemotherapies. The researchers now intend to block the molecules responsible for negative immune system activation to increase the efficiency of chemotherapy. A clinical trial to test this hypothesis should begin very soon.
Chemotherapy is one of the most frequently used treatments to eliminate cancerous cells. These drugs kill all cells that are multiplying, or block their proliferation (for example, cells responsible for hair growth, ...
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