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How bacteria talk to each other and our cells

2012-11-06
Bacteria can talk to each other via molecules they themselves produce. The phenomenon is called quorum sensing, and is important when an infection propagates. Now, researchers at Linköping University in Sweden are showing how bacteria control processes in human cells the same way. The results are being published in the journal PLOS Pathogens with Elena Vikström, researcher in Medical Microbiology, as the main author. When an infection is signaled, more and more bacteria gather at the site of the attack – a wound, for example. When there are enough of them, they start ...

Combating a crisis: Global burden of preterm birth can be reduced if critical actions are taken

2012-11-06
New surveys of researchers and funders reveal a lack of consensus regarding researching and developing interventions to prevent prematurity and stillbirth, according to an article published in the American Journal of Obstetrics and Gynecology ahead of World Prematurity Day on November 17. Authored by Michael G. Gravett, MD, scientific director of the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS), an initiative of Seattle Children's, and Craig E. Rubens, MD, PhD, executive director of GAPPS, the article outlines significant opportunities to enhance research ...

New bacteria to fight against intestinal inflammation

2012-11-06
This protection is provided by a human protein, Elafin, which is artificially introduced into dairy produce bacteria (Lactococcus lactis and Lactobacillus casei). In time, this discovery could be useful for individuals suffering from chronic inflammatory diseases such as Crohn's disease or ulcerative colitis. The results of this research were published in the Science Translational Medicine review on 31 October 2012. In France, nearly 200,000 individuals suffer from chronic inflammatory bowel disease, known as IBD, (specifically Crohn's disease and ulcerative colitis). ...

Supercomputing for a superproblem: A computational journey into pure mathematics

2012-11-06
A world-famous mathematician responsible for solving one of the subject's most challenging problems has published his latest work as a University of Leicester research report. This follows the visit that famed mathematician Yuri Matiyasevich made to the Department of Mathematics where he talked about his pioneering work. He visited UK by invitation of the Isaac Newton Institute for Mathematical Sciences. In 1900, twenty-three unsolved mathematical problems, known as Hilbert's Problems, were compiled as a definitive list by mathematician David Hilbert. A century later, ...

New strategy for fingerprint visualization developed at Hebrew University

New strategy for fingerprint visualization developed at Hebrew University
2012-11-06
Jerusalem, Nov. 6, 2012 -- Identifying fingerprints on paper is a commonly used method in police forensic work, but unfortunately it is not easy to make those fingerprints visible. Now, scientists at the Hebrew University of Jerusalem have developed a new approach for making such fingerprints more readily readable. The new method, created by a team headed by Prof. Yossi Almog and Prof. Daniel Mandler of the Institute of Chemistry at the Hebrew University, uses an innovative chemical process to produce a negative of the fingerprint image rather than the positive image ...

Strange diet for methane consuming microorganisms

Strange diet for methane consuming microorganisms
2012-11-06
This press release is available in German. Methane is formed under the absence of oxygen by natural biological and physical processes, e.g. in the sea floor. It is a much more powerful greenhouse gas than carbon dioxide. Thanks to the activity of microorganisms this gas is inactivated before it reaches the atmosphere and unfolds its harmful effects on Earth's climate. Researchers from Bremen have now proven that these microorganisms are quite picky about their diet. All life on Earth is based on carbon and its compounds. Cell components of all creatures contain carbon. ...

Early treatment sparks striking brain changes in autism

2012-11-06
When given early treatment, children with autism spectrum disorders (ASD) made significant improvements in behavior, communication, and most strikingly, brain function, Yale School of Medicine researchers report in a new study. The study was published in the current issue of the Journal of Autism and Developmental Disorders by Yale Child Study Center researchers Fred Volkmar, M.D., Kevin A. Pelphrey, and their colleagues. The results suggest that brain systems supporting social perception respond well to an early intervention behavioral program called pivotal response ...

HF patients treated by a cardiologist, rather than hospitalist, have fewer readmissions

2012-11-06
MINNEAPOLIS, MN – November 6, 2012 – When a cardiologist attends to heart failure patients, even when the severity of illness is higher, patients have reduced rates of hospital readmissions, compared with those patients who are treated by a hospitalist, according to a trial being presented today at the American Heart Association's scientific sessions in Los Angeles. Congestive heart failure (CHF) is the most common cause for hospital readmission in patients over the age of 65 years. Whereas efforts to reduce readmission rates have focused on transitions of care and short-term ...

Living abroad can bring success -- If you do it right

Living abroad can bring success -- If you do it right
2012-11-06
"Travel broadens the mind" goes the old adage, and potential employers often agree, valuing the open-mindedness and creativity fostered by such worldliness. But according to new Tel Aviv University research, not all international experiences are created equal. "Although living abroad does help to hone creative abilities, not all individuals who have lived abroad derive an equal benefit from such experiences," explains Dr. Carmit Tadmor of TAU's Recanati School of Business, who conducted the study with Dr. Adam Galinsky of the Kellogg School of Management at Northwestern ...

Team finds a new way to inhibit blood clotting and inflammation

Team finds a new way to inhibit blood clotting and inflammation
2012-11-06
CHAMPAIGN, lll. — Scientists have identified a group of small molecules that interfere with the activity of a compound that initiates multiple steps in blood clotting, including those that lead to the obstruction of veins or arteries, a condition called thrombosis. Blocking the activity of this compound, polyphosphate, could treat thrombosis with fewer bleeding side effects than the drugs that are currently on the market. Their findings appear in the journal Blood. Blood clots are formed at the site of an injured blood vessel to prevent blood loss. Sometimes, however, ...

New study reveals challenge facing designers of future computer chips

2012-11-06
To build the computer chips of the future, designers will need to understand how an electrical charge behaves when it is confined to metal wires only a few atom-widths in diameter. Now, a team of physicists at McGill University, in collaboration with researchers at General Motors R&D, have shown that electrical current may be drastically reduced when wires from two dissimilar metals meet. The surprisingly sharp reduction in current reveals a significant challenge that could shape material choices and device design in the emerging field of nanoelectronics. The size of ...

ICDs can reduce sudden death in young patients with hypertrophic cardiomyopathy

2012-11-06
MINNEAPOLIS, MN – November 5, 2012 – A multicenter registry has demonstrated that the use of implantable cardioverter-defibrillators (ICDs) to combat sudden cardiac death in high-risk pediatric patients suffering from hypertrophic cardiomyopathy (HCM). The study is being presented Nov. 5 at the 2012 Scientific Sessions of the American Heart Association (AHA) in Los Angeles. While the study found that the rate of possible device complications adds a level of complexity to this age group, it also demonstrated that life-saving ICD interventions were common in younger patients ...

Higher anxiety associated with poorer functioning in children with 22q11.2 deletion syndrome

2012-11-06
UC Davis researchers have found that for children with the genetic disorder known as chromosome 22q11.2 deletion syndrome anxiety -- but not intelligence -- is linked to poorer adaptive behaviors, such as self-care and communication skills, that affect daily life. The developmental syndrome, which is associated with a constellation of physical, cognitive and psychiatric problems, usually is apparent at birth or early childhood, and leads to lifelong challenges. The study findings suggest that helping children cope with fear-based symptoms may be the best strategy for ...

Overweight patients hospitalized with pneumonia more apt to survive

2012-11-06
Medical researchers at the University of Alberta studied the records of nearly 1000 patients who were admitted to hospital with pneumonia and noted those who were obese were more apt to survive compared to those who were of normal weight. For their research study, the team examined the records of 907 patients with pneumonia who were admitted to six Edmonton hospitals and also had their body mass index recorded. Two-thirds of the patients had severe pneumonia and 79 died in hospital. Of those who died, 12 were under weight, 36 were normal weight, 21 were overweight and ...

Older adults who are frail much more likely to be food insufficient, according to national study

2012-11-06
CORVALLIS, Ore. – A national study of older Americans shows those who have limited mobility and low physical activity – scientifically categorized as "frail" – are five times more likely to report that they often don't have enough to eat, defined as "food insufficiency," than older adults who were not frail. The nationally representative study of more than 4,700 adults older than age 60 in the United States uses data from the Third National Health and Nutrition Examination Survey. The results are online today in the British Journal of Nutrition. Lead author Ellen Smit, ...

Daily multivitamin use does not reduce cardiovascular disease risk in men

2012-11-06
Boston, Mass. – Approximately one-third of Americans take a daily multivitamin, but little is known about a multivitamin's long-term affect on chronic diseases. Now, new research from Brigham and Women's Hospital (BWH) finds that daily multivitamin use does not reduce the risk of cardiovascular disease in men. A similar BWH study, announced last month, found daily multivitamin use can reduce a man's risk of cancer by 8 percent. The cardiovascular disease findings will be presented Nov. 5 at the American Heart Association's Scientific Sessions 2012 and published simultaneously ...

Tech fund boosts Binghamton inventors

2012-11-06
BINGHAMTON, NY -- Binghamton University researcher Ron Miles invented a tiny directional microphone — suitable for use in hearing aids — that filters out unwanted sounds. Now, with help from the SUNY Technology Accelerator Fund, he hopes to bring the idea to the marketplace. Technology for the hearing-impaired is hardly perfect. The small microphones contained within hearing aids do a good job of boosting volume, but that can be a problem in a noisy restaurant as background sounds get boosted as much as your dinner date's conversation. Miles used a tiny structure found ...

Medical care presents update on pharmaceutical health services research

2012-11-06
Philadelphia, Pa. (November 5, 2012) - Pharmaceutical health services research goes beyond studying the effects of individual drugs, to looking at the complex and interrelated effects of medications on the health of patients and the population. The special November issue of Medical Care highlights important new papers in key areas of pharmaceutical health services research. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The 14 papers in the special issue cover a wide range of topics related to the health effects of marketed ...

Air exposure between blinks affects deposits on contact lenses

2012-11-06
Philadelphia, Pa. (November 5, 2012) - Modern contact lens materials are prone to drying when exposed to air, which contributes to the buildup of deposits on contact lenses, according to a study – "The Impact of Intermittent Air Exposure on Lipid Deposition", appearing in the November issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. With significant differences between materials, the buildup of lipid deposits on contact lenses is affected ...

Assessing the risk of heart attack and stroke among Hispanics

2012-11-06
A study published today in the Journal of the American Medical Association (JAMA) indicated that many Hispanic/Latino adults living in the United States are at high risk for heart attack or stroke. This risk is highest in men and in older people, born in the US or that have lived in the US more than 10 years, that prefer to speak English, are lower income, or never finished high school. "The finding that longer residence in the US increases disease risk may seem counterintuitive, but has previously been reported," says study co-author Schneiderman, James L. Knight Professor ...

We're more passive than we predict when sexually harassed, new study shows

2012-11-06
Sexual harassment is devastating in and of itself for its victims, but new research shows there can be an even more insidious and troubling consequence that goes along with it: When confronted with sexual harassment, we don't stand up for ourselves to the extent we believe we will, and because we use false predictions as a benchmark, we condemn others who are passive in the face of sexual harassment, according to a new study co-authored by Ann Tenbrunsel, professor of business ethics at the University of Notre Dame. In "Double Victimization in the Workplace: Why ...

Superbug MRSA identified in US wastewater treatment plants

2012-11-06
College Park, Md. – A team led by researchers at the University of Maryland School of Public Health has found that the "superbug" methicillin-resistant Staphylococcus aureus (MRSA) is prevalent at several U.S. wastewater treatment plants (WWTPs). MRSA is well known for causing difficult-to-treat and potentially fatal bacterial infections in hospital patients, but since the late 1990s it has also been infecting otherwise healthy people in community settings. "MRSA infections acquired outside of hospital settings – known as community-acquired MRSA or CA-MRSA– are on the ...

HIV and AIDS prevention--Progress and the challenges ahead

HIV and AIDS prevention--Progress and the challenges ahead
2012-11-06
New Rochelle, NY, November 5, 2012—At least 2 million people worldwide will be infected with HIV this year, driving the need for better HIV prevention strategies to slow the global pandemic. A better understanding of how to prevent HIV transmission using antiviral drugs led to approval of the first oral pill for HIV prevention, and microbicides delivered as topical gels or via intravaginal rings are in clinical testing and have yielded both positive and negative results. The complex factors involved in the sexual transmission of HIV, the urgent need for new preventive approaches, ...

Imaging facility develops successful radiation dose reduction program

2012-11-06
According to an article in the November issue of the Journal of the American College of Radiology, a medical imaging facility in San Diego, Imaging Healthcare Specialists, has implemented a successful radiation dose reduction program, reducing radiation exposure by up to 90 percent in some patients. "In the past decade, there have been unparalleled technological advances and growth in CT imaging, with many lives saved and more costly and invasive procedures avoided. This growth in CT imaging, however, has also been accompanied by an unavoidable increase in cumulative ...

November 2012 story tips

2012-11-06
ENVIRONMENT – Ozone affecting watersheds . . . U.S. Forest Service and Oak Ridge National Laboratory scientists have found that rising levels of ozone may amplify the impacts of higher temperatures and reduce streamflow from forests to rivers, streams and other water bodies. Such effects could potentially reduce water supplies available to support forest ecosystems and people in the southeastern United States. Using data on atmospheric water supply and demand and statistical models, researchers with the Forest Service and ORNL were able to show what effects ozone, categorized ...
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