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Strengthening Canada's research capacity: The gender dimension

2012-11-21
Ottawa (November 23rd, 2012) - An in-depth, authoritative assessment of women in university research has found that although there has been significant progress in the representation of women in the university research ranks, there are still gender equity challenges that must be overcome and the passage of time will not be enough to ensure parity. A newly released report by the Council of Canadian Academies entitled, Strengthening Canada's Research Capacity: The Gender Dimension provides an assessment of the the factors that influence university research careers of women. ...

Novel mechanism through which normal stromal cells become cancer-promoting cells identified

2012-11-21
PHILADELPHIA — New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research. "New approaches for treating patients with ovarian cancer are desperately needed," said Ernst Lengyel, M.D., Ph.D., professor in the department of obstetrics and gynecology at the University of Chicago. "There have been no new approaches ...

MicroRNAs can convert normal cells into cancer promoters

2012-11-21
Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease. In the December issue of the American Association for Cancer Research journal Cancer Discovery, a team or researchers from the University of Chicago Medicine and Northwestern University Feinberg School of Medicine show that ovarian cancer cells induce nearby cells to alter their production of three microRNAs—small strands of genetic material that are important regulators ...

Early birds had an old-school version of wings

2012-11-21
In comparison to modern birds, the prehistoric Archaeopteryx and bird-like dinosaurs before them had a more primitive version of a wing. The findings, reported on November 21 in Current Biology, a Cell Press publication, lend support to the notion that birds are the descendants of gliding dinosaurs that spent much of their days in the trees. "By studying fossils carefully, we are now able to start piecing together how the wing evolved," said Nicholas Longrich of Yale University. "Before, it seemed that we had more or less modern wings from the Jurassic onwards. Now it's ...

Drug resistance biomarker could improve cancer treatment

2012-11-21
Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published by Cell Press November 21st in the journal Cell. The study reveals a biomarker that can predict responses to cancer drugs and offers a strategy to treat drug-resistant tumors based on their genetic signature. "We need to understand the mechanisms of drug resistance to effectively prevent it from occurring in the first place," says senior study author ...

Biomarking time

2012-11-21
Women live longer than men. Individuals can appear or feel years younger – or older – than their chronological age. Diseases can affect our aging process. When it comes to biology, our clocks clearly tick differently. In a new study, researchers at the University of California, San Diego School of Medicine, with colleagues elsewhere, describe markers and a model that quantify how aging occurs at the level of genes and molecules, providing not just a more precise way to determine how old someone is, but also perhaps anticipate or treat ailments and diseases that come ...

Brain waves encode rules for behavior

2012-11-21
CAMBRIDGE, MA -- One of the biggest puzzles in neuroscience is how our brains encode thoughts, such as perceptions and memories, at the cellular level. Some evidence suggests that ensembles of neurons represent each unique piece of information, but no one knows just what these ensembles look like, or how they form. A new study from researchers at MIT and Boston University (BU) sheds light on how neural ensembles form thoughts and support the flexibility to change one's mind. The research team, led by Earl Miller, the Picower Professor of Neuroscience at MIT, identified ...

A*STAR scientists identify potential drug target for inflammatory diseases including cancers

2012-11-21
A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as diabetes. This enzyme, which is known to be responsible for providing cancer cells the endless ability to divide, is now found to also jumpstart and maintain chronic inflammation in cancers. In identifying this enzyme, inflammation can be prevented or reduced, and the common ...

Feature package of Congo Basin forest photos, stories & videos

2012-11-21
Stretching across central Africa, the Congo Basin forest is the second largest tract of rainforest in the world and a lifeline for more than 60 million people – providing food and income for many remote communities, storing huge amounts of carbon, supporting unique ecosystems and regulating the flow of the major rivers across Central Africa. Yet the Congo's forests are being cleared at an alarming rate amid global demand for the continent's minerals, energy and wood resources. Current methods and rates of extracting these resources are unsustainable and threatening the ...

Kidney tumors have a mind of their own

2012-11-21
TORONTO, Nov. 21, 2012-- New research has found there are several different ways that kidney tumours can achieve the same result – namely, grow. Scientists have been trying to figure out how different people have kidney tumours with the same histology, or shape, although the genetic changes can vary among individual tumours. Solving that puzzle could have implications for the diagnosis and treatment if kidney cancer, which has 35 per cent mortality rate and is becoming more common. Despite advances in early detection and treatment, the mortality rate hasn't changed in ...

The most popular TV series among youngsters in Spain recreates violence

2012-11-21
Published in the Comunicación journal, a study conducted by the University of Seville analyses violence content in Spanish TV series. It concludes that Telecinco's Sin tetas no hay paraíso is the most violent of the five studied. Despite the fact that other series have more scenes or minutes of violence, according to the study, the Telecinco series is more powerful in its transmission of values that are more detrimental to youngsters in terms of their perception of aggressive behaviour and its consequences. Sara González, the author of the study, explains to SINC ...

Flower power to purge poison and produce platinum

Flower power to purge poison and produce platinum
2012-11-21
A consortium of researchers led by WMG at the University of Warwick are to embark on a £3 million research programme called "Cleaning Land for Wealth" (CL4W), that will use a common class of flower to restore poisoned soils while at the same time producing perfectly sized and shaped nano sized platinum and arsenic nanoparticles for use in catalytic convertors, cancer treatments and a range of other applications. A "Sandpit" exercise organised by the Engineering and Physical Sciences Research Council (EPSRC) allowed researchers from WMG (Warwick Manufacturing group) at ...

Researchers detail the migrations of the wood wasp Sirex noctilio

2012-11-21
In order to find out about its migrations, various research centres in South Africa, Sweden, Canada, Chile, Australia, Spain, Argentina and Switzerland have conducted research detailing its routes and expansion periods. A significant new fact has emerged and it is that the wasps returning to Europe from Chile and South Africa have undergone a genetic micro-evolution which makes them more resistant to their natural European enemy, a nematode that sterilises them. The Sirex noctilio wasp is regarded as a secondary pest in Europe because in this geographical area there is ...

VTT: Indicators and methods of sustainable development 1-sided

2012-11-21
"Methods are required that take the social and environmental impacts of business operations better into account, both within the company and among its network of partners and stakeholders," says Uusitalo. "If a change cannot be effected, the current unsustainable way of life will continue, and we might also miss some opportunities for creating new business. Market share is at stake here." According to Uusitalo, other companies and customers demand that companies take a wider view of sustainable development. "Legislation will also inevitably lead development in this ...

Herbivore defense in ferns

Herbivore defense in ferns
2012-11-21
This press release is available in German. They dominated the earth for 200 million years and numerous different species can still be found all over the world: mosses, horsetails and ferns. Researchers from the Max Planck Institute for Chemical Ecology in Jena, Germany, have now found out that bracken ferns (Pteridium aquilinum) do not release any volatiles when they are attacked − unlike many of the now dominant and evolutionary younger flowering plants. Such an emission of volatile compounds may attract the pest insects' enemies, such as ichneumon wasps or ...

Researchers identify a simple way to precipitate phosphorus from the wastewater of a pulp mill

Researchers identify a simple way to precipitate phosphorus from the wastewater of a pulp mill
2012-11-21
Researchers at Aalto University have developed a simple method for reducing the amount of phosphorus in the wastewater of a pulp mill. The method is called simultaneous precipitation using iron sulphate. A separate treatment stage is not required, as the precipitation takes place simultaneously with the actual biological wastewater treatment. Iron sulphate is added to the wastewater prior to the biological wastewater treatment process, and the phosphorus dissolved into the water is precipitated with the biomass at the treatment plant. Finally, the phosphorus is removed ...

'Trust' provides answer to handaxe enigma

2012-11-21
Trust rather than lust is at the heart of the attention to detail and finely made form of handaxes from around 1.7 million years ago, according to a University of York researcher. Dr Penny Spikins, from the Department of Archaeology, suggests a desire to prove their trustworthiness, rather than a need to demonstrate their physical fitness as a mate, was the driving force behind the fine crafting of handaxes by Homo erectus/ergaster in the Lower Palaeolithic period. Dr Spikins said: "We sometimes imagine that early humans were self-centred, and if emotional at all, that ...

Ocean currents play a role in predicting extent of Arctic sea ice

2012-11-21
CAMBRIDGE, MA -- Each winter, wide swaths of the Arctic Ocean freeze to form sheets of sea ice that spread over millions of square miles. This ice acts as a massive sun visor for the Earth, reflecting solar radiation and shielding the planet from excessive warming. The Arctic ice cover reaches its peak each year in mid-March, before shrinking with warmer spring temperatures. But over the last three decades, this winter ice cap has shrunk: Its annual maximum reached record lows, according to satellite observations, in 2007 and again in 2011. Understanding the processes ...

Daily steps add up for midlife women's health

2012-11-21
CLEVELAND, Ohio (November 21, 2012)—Moving 6,000 or more steps a day—no matter how—adds up to a healthier life for midlife women. That level of physical activity decreases the risk of diabetes and metabolic syndrome (a diabetes precursor and a risk for cardiovascular disease), showed a study published online this month in Menopause, the journal of the North American Menopause Society. Although other studies have shown the value of structured exercise in lowering health risks such as diabetes, high blood pressure, and heart disease, this study has shown that habitual physical ...

Brainy babies – Research explores infants' skills and abilities

2012-11-21
Infants seem to develop at an astoundingly rapid pace, learning new things and acquiring new skills every day. And research suggests that the abilities that infants demonstrate early on can shape the development of skills later in life, in childhood and beyond. Read about the latest research on infant development published in the November 2012 issue of Psychological Science, a journal of the Association for Psychological Science. How Do You Learn to Walk? Thousands of Steps and Dozens of Falls per Day How do babies learn to walk? In this study, psychological scientist ...

Short DNA strands in the genome may be key to understanding human cognition and diseases

2012-11-21
Short snippets of DNA found in human brain tissue provide new insight into human cognitive function and risk for developing certain neurological diseases, according to researchers from the Departments of Psychiatry and Neuroscience at Mount Sinai School of Medicine. The findings are published in the November 20th issue of PLoS Biology. There are nearly 40 million positions in the human genome with DNA sequences that are different than those in non-human primates, making the task of learning which are important and which are inconsequential a challenge for scientists. ...

It takes two to tangle: Wistar scientists further unravel telomere biology

2012-11-21
Chromosomes - long, linear DNA molecules – are capped at their ends with special DNA structures called telomeres and an assortment of proteins, which together act as a protective sheath. Telomeres are maintained through the interactions between an enzyme, telomerase, and several accessory proteins. Researchers at The Wistar Institute have defined the structure of one of these critical proteins in yeast. Understanding how telomeres keep chromosomes – and by extension, genomes – intact is an area of intense scientific focus in the fields of both aging and cancer. In aging, ...

Pathway identified in human lymphoma points way to new blood cancer treatments

Pathway identified in human lymphoma points way to new blood cancer treatments
2012-11-21
PHILADELPHIA – A pathway called the "Unfolded Protein Response," or UPR, a cell's way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma. Research, led by Lori Hart, Ph.D., research associate and Constantinos Koumenis, Ph.D., associate professor,and research division director in the Department of Radiation Oncology, both from the Perelman School of Medicine, University of Pennsylvania, and Davide Ruggero, Ph.D., associate professor, Department of Urology, University of California, San Francisco, ...

University of Tennessee study: Unexpected microbes fighting harmful greenhouse gas

2012-11-21
The environment has a more formidable opponent than carbon dioxide. Another greenhouse gas, nitrous oxide, is 300 times more potent and also destroys the ozone layer each time it is released into the atmosphere through agricultural practices, sewage treatment and fossil fuel combustion. Luckily, nature has a larger army than previously thought combating this greenhouse gas—according to a study by Frank Loeffler, University of Tennessee, Knoxville–Oak Ridge National Laboratory Governor's Chair for Microbiology, and his colleagues. The findings are published in the ...

Saving water without hurting peach production

2012-11-21
U.S. Department of Agriculture (USDA) scientists are helping peach growers make the most of dwindling water supplies in California's San Joaquin Valley. Agricultural Research Service (ARS) scientist James E. Ayars at the San Joaquin Valley Agricultural Sciences Center in Parlier, Calif., has found a way to reduce the amount of water given post-harvest to early-season peaches so that the reduction has a minimal effect on yield and fruit quality. ARS is USDA's principal intramural scientific research agency, and the research supports the USDA priority of promoting international ...
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