Toronto – Brokers are supposed to recommend investments that are in the best interests of their clients. But a study published in the February 2013 issue of the Journal of Finance has found that mutual funds offering higher broker fees attract the most investments, especially when the broker is not affiliated with the mutual fund company. Every additional dollar paid to a broker corresponds with another six dollars invested into the fund, and another fourteen dollars if the broker is an unaffiliated third party whose compensation depends exclusively on sales commissions. ...

Disrupting a key interaction between two types of proteins in cells inhibits the spread of cancerous cells, providing researchers with a new pathway toward developing cancer-fighting drugs, according to new findings by Georgia State University scientists. Cell migration is essential for the spread of cancerous cells, also known as metastasis, as well as for other diseases. The research team in the labs of Zhi-Ren Liu, professor of biology, and Jenny Yang, professor of biochemistry, studied the interaction of two molecules, p68 RNA helicase and calcium-calmodulin. Interrupting ...

Bulky and noisy air-conditioning compressors and refrigerators may soon be a thing of the past. With the latest discovery by scientists from Nanyang Technological University (NTU), current cooling systems which uses refrigerant harmful to the ozone layer could be replaced by a revolutionary cooling system using lasers. This discovery, published and featured on the cover of the 24 January 2013 issue of Nature, the world's top scientific journal, could also potentially lead to a host of other innovations. This includes making huge Magnetic Resonance Imaging (MRI) machines, ...

Nurses are the largest group of health care providers in the U.S., and health care leaders and experts agree that engaging registered nurses (RNs) in quality improvement (QI) efforts is essential to improving our health care system, patient care and our nation's health. Unfortunately, despite studies demonstrating the value of nurse-led quality improvement efforts, far too few nurses are involved in these efforts, and the number is not growing, according to a study published in the Journal of Nursing Care Quality. The study—part of the RN Work Project funded by the Robert ...

ANN ARBOR—Working beneath the towering oaks and maples on the University of Michigan's central campus Diag, undergraduate researchers and their faculty adviser helped explain an observation that had puzzled insect ecologists who study voracious leaf-munching gypsy moth caterpillars. The caterpillars, which defoliate and sometimes kill stands of trees in the Upper Midwest and the Northeast, are especially fond of oaks, but sugar maple trees appear to be relatively resistant to the European pest. Biologists wondered whether the caterpillars shun sugar maples in part because ...

"We have continued with our study and for the first time are able to present a five-year follow-up on the need for and results of ACL surgery as compared with physiotherapy. The findings have been published in the British Medical Journal and are basically unchanged from 2010. This will no doubt surprise many people, as we have not seen any difference in the incidence of osteoarthritis", says Richard Frobell, one of the researchers behind the study, who is an associate professor at Lund University and a clinician at the orthopaedic department, Helsingborg Hospital. Richard ...

(Boston)–Researchers at Boston University School of Medicine (BUSM) led by Carmela Abraham, PhD, professor of biochemistry, along with Cidi Chen, PhD, and other collaborators, report that the protein Klotho plays an important role in the health of myelin, the insulating material allowing for the rapid communication between nerve cells. These findings, which appear online in Journal of Neuroscience, may lead to new therapies for multiple sclerosis (MS) and Alzheimer's disease (AD), in which white matter abnormalities are also common but have been largely ignored. MS is ...

A new study provides the first evidence of polyandry – when females choose to mate with more than one male – in female fallow deer. According to a team of scientists from Queen Mary, University of London, UWEHartpury, and University College Dublin, female fallow deer play an active role in selecting their mates, with a consistent proportion (on average 12 per cent) choosing to mate with multiple males each year. "Until now there has been limited understanding of female mate choice during this process, with many people believing that female deer are controlled by males ...

In an advance toward closing a major gap in defenses against terrorist attacks and other mass casualty events, scientists are reporting discovery of a promising substance that could be the basis for development of a better antidote for cyanide poisoning. Their report, which describes a potential antidote that could be self-administered, much like the medication delivered by allergy injection pens, appears in ACS' Journal of Medicinal Chemistry. Steven E. Patterson, Ph.D., and colleagues at the University of Minnesota Center for Drug Design explain that the only existing ...

CAMBRIDGE, MA -- For immigrants, the path to citizenship in many countries is filled with hurdles: finding a job, learning the language, passing exams. But for some people, the biggest obstacle of all may be one they cannot help: their country of origin. That's one conclusion of a methodologically innovative study of European immigrants suggesting that, other qualifications being equal, migrants from certain countries may be roughly 40 percent less likely than others to gain citizenship. Even if an immigrant has obtained a good education and job, and solid language ...

Mention mobile applications, or mobile apps, and people think of games, email, news, weather, productivity and other software for Apple, Android and other smart phones and tablet computers. But an app with broader impact — the first mobile application to foster wider use of the environmentally friendly and sustainable principles of green chemistry — is the topic of a report in the American Chemical Society's new journal, ACS Sustainable Chemistry & Engineering. Sean Ekins, Alex M. Clark and Antony Williams point out that the companies that manufacture medicines, electronics ...

A team of scientists at Umeå University, in collaboration with colleagues in Melbourne, Australia, have found that television viewing and lack of exercise at age 16 is associated with the risk of developing metabolic syndrome at 43 years age. Metabolic syndrome is a name for the disorder of metabolism - a combination of abdominal obesity, elevated blood lipids, hypertension and impaired glucose tolerance - which provides for a significantly increased risk of developing type 2 diabetes, stroke and cardiovascular disease. It has previously been shown that lack of physical ...

Comet explosions did not end the prehistoric human culture, known as Clovis, in North America 13,000 years ago, according to research published in the journal Geophysical Monograph Series. Researchers from Royal Holloway university, together with Sandia National Laboratories and 13 other universities across the United States and Europe, have found evidence which rebuts the belief that a large impact or airburst caused a significant and abrupt change to the Earth's climate and terminated the Clovis culture. They argue that other explanations must be found for the apparent ...

Philadelphia, PA, January 30, 2013 – Once heavy drinking impairs function, a variety of punishment-related threats may motivate people to stop drinking: spouses may threaten divorce, employers may threaten job loss, and courts threaten drunk drivers with losing their driver's license or incarceration. In the face of these threats, many alcohol abusers refrain from drinking, but relapse is very common when the threats of punishment fade, particularly when exposed to alcohol-associated environments (contexts). A new study by researchers at the National Institute on Drug ...

A new analysis has found that some second trimester markers for Down's syndrome that are detected by ultrasound are more telling than others. Published early online in Ultrasound in Obstetrics & Gynecology, the study's results will help adjust pregnant women's risks for having a child with the condition. Screening for Down's syndrome is offered to all pregnant women, who start out with a background risk based on their age. Certain features detected during a second trimester ultrasound exam are potential markers for Down's syndrome, and they include dilated brain ventricles, ...

Forestry and nature conservation can benefit from promoting more different varieties of trees, according to a new study in which researchers from the University of Gothenburg, Sweden, were involved. Modern forestry is based largely on monocultures – usually pine or spruce trees in Sweden – mainly because this is seen to be more rational. However, a forest also contributes ecosystem services other than just wood production, such as biological diversity, carbon sequestration and berries. A new study by the Swedish University of Agricultural Sciences (SLU) and Future Forests ...

Western babies are potty trained later these days and need diapers until an average of three years of age. But even infants can be potty trained. A study by researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, followed 47 infants and their mothers in Vietnam – where potty training starts at birth and the need for diapers is usually eliminated by nine months of age. Not only does eliminating the need for diapers save money and remove one practical chore for parents, but the baby's ability to control its bladder improves efficiency and reduces the risk ...

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people. Functional signs of brain damage from alcohol misuse in young people mainly include deficits in visual learning and memory as well as executive functions. These functions are controlled by the hippocampus and frontal structures of the brain, which are not fully mature until ...

This press release is available in German. Up to now, it has been a case of "either/or." On the one hand, we have the typical ultra-compact, lightweight electric car, where designers have had to compromise on safety. With larger e-cars on the other hand, the heavier frames and crumple zones come at the expense of battery range. But now researchers as well as engineers from some of Germany's top technology firms are looking to create the best of both worlds. The aim of the Visio.M project is to develop a mobility concept for an efficient electric vehicle, making ...

In this week's issue of the prestigious journal Nature Chemical Biology, scientists Carole Linster (University of Luxembourg), Emile Van Schaftingen (Louvain University), and Andrew D. Hanson (University of Florida, Gainesville) review an important, but so far neglected, part of metabolism, namely metabolite damage-control. In their publication 'Metabolite damage and its repair or pre-emption', the authors present a comprehensive overview of the known reactions generating unwanted small molecules in the cell as well as of the corresponding control mechanisms, and discuss ...

New research has shown that a protein, known as IL-13, could be the key to the development of fibrosis in Crohn's disease. This breakthrough could help to advance new medicines to treat people suffering with the disease. Crohn's disease is a chronic, debilitating condition characterised by inflammation and ulceration occurring at any point in the gastrointestinal tract. Currently there is no cure. One of the major complications of Crohn's disease is the development of fibrosis – hardening and thickening – in the bowel wall. This causes the intestine to lose its mobility ...

BEND, Ore. – A new study by Oregon State University researchers finds that Head Start can make a positive impact in the lives of some of its highest risk children, both academically and behaviorally. Published in the current issue of the Journal of Applied Developmental Psychology, the study sheds light on how Head Start has helped children living in non-parental care, or living with someone who is not a parent or step-parent by biology or adoption. "These children tend to have unstable home lives, sometimes transitioning between different relatives, living with their ...

An international team of researchers has shown that old wives' tales that snails can tell us about the weather should not be dismissed too hastily. While the story goes that if a snail climbs a plant or post, rain is coming, research led by the University of York goes one better: it shows snails can provide a wealth of information about the prevailing weather conditions thousands of years ago. The researchers, including scientists from the Scottish Universities Environmental Research Centre (SUERC), analysed the chemistry of snail shells dating back 9,000 to 2,500 years ...

AUGUSTA, Ga. – Scientists have found an early step in how the brain's inhibitory cells get excited. A natural balance of excitement and inhibition keeps the brain from firing electrical impulses randomly and excessively, resulting in problems such as schizophrenia and seizures. However excitement is required to put on the brakes. "When the inhibitory neuron is excited, its job is to suppress whatever activity it touches," said Dr. Lin Mei, Director of the Institute of Molecular Medicine and Genetics at the Medical College of Georgia at Georgia Regents University ...

Enzymes, workhorse molecules of life that underpin almost every biological process, may have a new role as "intelligent" micro- and nanomotors with applications in medicine, engineering and other fields. That's the topic of a report in the Journal of the American Chemical Society, showing that single molecules of common enzymes can generate enough force to cause movement in specific directions. Peter J. Butler, Ayusman Sen and colleagues point out that enzymes — proteins that jump-start chemical reactions — are the basis of natural biological motors essential to life. ...