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News tips from the journal mBio

2011-11-03
Antibodies Trick Bacteria into Killing Each Other The dominant theory about antibodies is that they directly target and kill disease-causing organisms. In a surprising twist, researchers from the Albert Einstein College of Medicine have discovered that certain antibodies to Streptococcus pneumoniae actually trick the bacteria into killing each other. Pneumococcal vaccines currently in use today target the pneumococcal capsular polysaccharide (PPS), a sort of armor that surrounds the bacterial cell, protecting it from destruction. Current thought hold that PPS-binding ...

Solar power could get boost from new light absorption design

2011-11-03
Solar power may be on the rise, but solar cells are only as efficient as the amount of sunlight they collect. Under the direction of a new professor at Northwestern University's McCormick School of Engineering and Applied Science, researchers have developed a new material that absorbs a wide range of wavelengths and could lead to more efficient and less expensive solar technology. A paper describing the findings, "Broadband polarization-independent resonant light absorption using ultrathin plasmonic super absorbers," was published Tuesday in the journal Nature Communications. "The ...

Exenatide (Byetta) has rapid, powerful anti-inflammatory effect, UB study shows

2011-11-03
BUFFALO, N.Y. -- Exenatide, a drug commonly prescribed to help patients with type 2 diabetes improve blood sugar control, also has a powerful and rapid anti-inflammatory effect, a University at Buffalo study has shown. The study of the drug, marketed under the trade name Byetta, was published recently in the Journal of Clinical Endocrinology and Metabolism. "Our most important finding was this rapid, anti-inflammatory effect, which may lead to the inhibition of atherosclerosis, the major cause of heart attacks, strokes and gangrene in diabetics," says Paresh Dandona, ...

Manufacturing microscale medical devices for faster tissue engineering

Manufacturing microscale medical devices for faster tissue engineering
2011-11-03
WASHINGTON, Nov. 2—In the emerging field of tissue engineering, scientists encourage cells to grow on carefully designed support scaffolds. The ultimate goal is to create living structures that might one day be used to replace lost or damaged tissue, but the manufacture of appropriately detailed scaffolds presents a significant challenge that has kept most tissue engineering applications confined to the research lab. Now a team of researchers from the Laser Zentrum Hannover (LZH) eV Institute in Hannover, Germany, and the Joint Department of Biomedical Engineering at the ...

Dirt prevents allergy

2011-11-03
Oversensitivity diseases, or allergies, now affect 25 per cent of the population of Denmark. The figure has been on the increase in recent decades and now researchers at the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), University of Copenhagen, are at last able to partly explain the reasons. "In our study of over 400 children we observed a direct link between the number of different bacteria in their rectums and the risk of development of allergic disease later in life," says Professor Hans Bisgaard, consultant at Gentofte Hospital, head of the Copenhagen ...

Cardiovascular magnetic resonance now an important first-line test

2011-11-03
Philadelphia, PA, November 2, 2011 – Cardiovascular Magnetic Resonance (CMR) has undergone substantial development and offers important advantages compared with other well-established imaging modalities. In the November/December issue of Progress in Cardiovascular Diseases, published by Elsevier, a series of articles on key topics in CMR will foster greater understanding of the rapidly expanding role of CMR in clinical cardiology. "Until a decade ago, CMR was considered mostly a research tool, and scans for clinical purpose were rare," stated guest editors Theodoros ...

Thousand-color sensor reveals contaminants in Earth and sea

Thousand-color sensor reveals contaminants in Earth and sea
2011-11-03
The world may seem painted with endless color, but physiologically the human eye sees only three bands of light — red, green, and blue. Now a Tel Aviv University-developed technology is using colors invisible to the naked eye to analyze the world we live in. With the ability to detect more than 1,000 colors, the "hyperspectral" (HSR) camera, like Mr. Spock's sci-fi "Tricorder," is being used to "diagnose" contaminants and other environmental hazards in real time. Prof. Eyal Ben-Dor of TAU's Department of Geography and the Human Environment says that reading this extensive ...

Rutgers neuroscientist says protein could prevent secondary damage after stroke

2011-11-03
One of two proteins that regulate nerve cells and assist in overall brain function may be the key to preventing long-term damage as a result of a stroke, the leading cause of disability and third leading cause of death in the United States. In a recent study published in the Journal of Neuroscience, Bonnie Firestein, professor of cell biology and neuroscience, in the School of Arts and Sciences, says the new research indicates that increased production of two proteins – cypin and PSD-95 – results in very different outcomes. While cypin – a protein that regulates nerve ...

Study reveals details of alternative splicing circuitry that promotes cancer's Warburg effect

2011-11-03
Cold Spring Harbor, N.Y. – Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose – a phenomenon known as the Warburg effect. Professor Adrian Krainer, Ph.D., and his team at Cold Spring Harbor Laboratory (CSHL), who seek to reverse this effect and force cancer cells to regain the metabolism of normal cells, have discovered details of molecular events that cause cancer cells to produce PK-M2 instead of its harmless counterpart, an isoform ...

Mysterious absorption lines could illuminate 90-year puzzle

2011-11-03
The discovery of 13 diffuse interstellar bands with the longest wavelengths to date could someday solve a 90-year-old mystery. Astronomers have identified the new bands using data collected by the Gemini North telescope of stars in the center of the Milky Way. Nature reports on its website today findings that support recent ideas about the presence of large, possibly carbon-based organic molecules—"carriers"—hidden in interstellar dust clouds. The paper will also appear in the Nov. 10 print issue of the journal. "These diffuse interstellar bands—or DIBs—have never ...

Homo sapiens arrived earlier in Europe than previously known

Homo sapiens arrived earlier in Europe than previously known
2011-11-03
Members of our species (Homo sapiens) arrived in Europe several millennia earlier than previously thought. At this conclusion a team of researchers, led by the Department of Anthropology, University of Vienna, arrived after re-analyses of two ancient deciduous teeth. These teeth were discovered 1964 in the "Grotta del Cavallo", a prehistoric cave in southern Italy. Since their discovery they have been attributed to Neanderthals, but this new study suggests they belong to anatomically modern humans. Chronometric analysis, carried out by the Oxford Radiocarbon Accelerator ...

Geologists find ponds not the cause of arsenic poisoning in India's groundwater

2011-11-03
MANHATTAN, Kan. -- The source of arsenic in India's groundwater continues to elude scientists more than a decade after the toxin was discovered in the water supply of the Bengal delta in India. But a recent study with a Kansas State University geologist and graduate student, as well as Tulane University, has added a twist -- and furthered the mystery. Arsenic is a naturally occurring trace element, and it causes skin lesions, respiratory failure and cancer when present in high concentrations in drinking water. The environmental crisis began after large traces of the element ...

LSU researchers find link between personality and credit scores

2011-11-03
BATON ROUGE – The use of credit scores as employment screening tools is a hotly debated topic. According to a 2010 poll by the Society for Human Resource Management, 60 percent of surveyed employers conducted credit checks for some or all candidates as part of the hiring process. With unemployment rates in the United States at double digits, losing a career opportunity has a potentially higher impact than nearly ever before, while the nationwide wave of foreclosures simultaneously makes it more likely for an individual to have a black mark on their record. In an upcoming ...

eLearners.com Career Confidence Poll Indicates a Confidence Crisis Among Americans

2011-11-03
Amid high unemployment rates and a volatile job market, new research released today by eLearners.com signals even greater concern among Americans. Even those employed lack the confidence that they have what it takes to remain competitive in their careers. The eLearners.com Career Confidence Poll found that 22 percent of Americans over the age of 18 don't feel competitive long-term (5+ years) and that among the employed, nearly one in four (23 percent) don't even feel they can remain competitive for the next two years. "America's economic recovery and long-term ...

Analysis reveals malaria, other diseases as ancient, adaptive and persistent foes

2011-11-03
CORVALLIS, Ore. – One of the most comprehensive analyses yet done of the ancient history of insect-borne disease concludes for the first time that malaria is not only native to the New World, but it has been present long before humans existed and has evolved through birds and monkeys. The findings, presented in a recent issue of American Entomologist by researchers from Oregon State University, are based on the study of insect specimens preserved in amber. The study outlines the evolution of several human diseases, including malaria, leishmaniasis and trypanosomiasis. ...

Genome-scale network of rice genes to speed the development of biofuel crops

Genome-scale network of rice genes to speed the development of biofuel crops
2011-11-03
The first genome-scale model for predicting the functions of genes and gene networks in a grass species has been developed by an international team of researches that includes scientists with the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI), a multi-institutional partnership led by Lawrence Berkeley National Laboratory (Berkeley Lab). Called RiceNet, this systems-level model of rice gene interactions should help speed the development of new crops for the production of advanced biofuels, as well as help boost the production and improve the quality ...

Interactive play with blocks found to facilitate development of spatial vocabulary

2011-11-03
In a recent study published in Mind, Brain and Education, researchers at Temple's Infant Lab found there are some very real benefits to playing with that old toy classic — blocks. Parents and researchers have long speculated that play with construction toys might offer a rich environment that would support later learning in the science, technology, engineering and mathematics (STEM) disciplines. The study led by Katrina Ferrara found that when playing with blocks under interactive conditions, children hear the kind of language that helps them think about space, such ...

New study reveals coral reefs may support much more biodiversity than previously thought

New study reveals coral reefs may support much more biodiversity than previously thought
2011-11-03
Smithsonian scientists and colleagues conducted the first DNA barcoding survey of crustaceans living on samples of dead coral taken from the Indian, Pacific and Caribbean oceans. The results suggest that the diversity of organisms living on the world's coral reefs is seriously underestimated. The team's research "The Diversity of Coral Reefs: What Are We Missing?" was published in October in the journal PLoS ONE. At depths of 26 to 39 feet, the scientists collected dead coral from five different locations. At two sites where removing coral is prohibited, the scientists ...

UCSB physicists identify room temperature quantum bits in widely used semiconductor

UCSB physicists identify room temperature quantum bits in widely used semiconductor
2011-11-03
Santa Barbara, Calif. –– A discovery by physicists at UC Santa Barbara may earn silicon carbide –– a semiconductor commonly used by the electronics industry –– a role at the center of a new generation of information technologies designed to exploit quantum physics for tasks such as ultrafast computing and nanoscale sensing. The research team discovered that silicon carbide contains crystal imperfections that can be controlled at a quantum mechanical level. The finding is published this week in the journal Nature. The research group of David Awschalom, senior author, ...

Texas A&M professor helping to unravel causes of Ice Age extinctions

2011-11-03
COLLEGE STATION -- Did climate change or humans cause the extinctions of the large-bodied Ice Age mammals (commonly called megafauna) such as the woolly rhinoceros and woolly mammoth? Scientists have for years debated the reasons behind the Ice Age mass extinctions, which caused the loss of a third of the large mammals in Eurasia and two thirds of the large mammals in North America, and now, an inter-disciplinary team from more than 40 universities around the world led by Professor Eske Willerslev and his group from the Centre for GeoGenetics, University of Copenhagen, ...

Fruit fly intestine may hold secret to the fountain of youth

Fruit fly intestine may hold secret to the fountain of youth
2011-11-03
One of the few reliable ways to extend an organism's lifespan, be it a fruit fly or a mouse, is to restrict calorie intake. Now, a new study in fruit flies is helping to explain why such minimal diets are linked to longevity and offering clues to the effects of aging on stem cell behavior. Scientists at the Salk Institute for Biological Studies and their collaborators found that tweaking a gene known as PGC-1, which is also found in human DNA, in the intestinal stem cells of fruit flies delayed the aging of their intestine and extended their lifespan by as much as 50 ...

Maryland climate plan passes key tests in UMD studies

Maryland climate plan passes key tests in UMD studies
2011-11-03
COLLEGE PARK, Md. - Maryland's plan to cut greenhouse gas emissions 25 percent by 2020 meets a series of benchmark tests set by state lawmakers, concludes a new pair of studies by the University of Maryland Center for Integrative Environmental Research (CIER). The findings should help clear the way for adoption of a full Climate Action Plan next year, the researchers say. Maryland's 2009 Greenhouse Gas Reduction Act ordered independent studies to make sure that its provisions won't hurt the reliability of the state's electricity supply or damage the manufacturing sector ...

Study: Crop diversity myths persist in media

Study: Crop diversity myths persist in media
2011-11-03
CHAMPAIGN, Ill. – The conventional wisdom that says the 20th century was a disaster for crop diversity is nothing more than a myth, according to a forthcoming study by a University of Illinois expert in intellectual property law. Law professor Paul Heald says overall varietal diversity of the $20 billion market for vegetable crops and apples in the U.S. actually has increased over the past 100 years, a finding that should change the highly politicized debate over intellectual property policy. "The conventional wisdom, as illustrated in the July 2011 issue of National ...

Unsaturated fat breakdown leads to complications of acute pancreatitis in obese patients

2011-11-03
PITTSBURGH -- The toxic byproducts produced by the breakdown of unsaturated fats lead to a higher likelihood of severe inflammation, cell death and multi-system organ failure among acute pancreatitis patients who are obese, say researchers at the University of Pittsburgh School of Medicine. Their findings, published online today in Science Translational Medicine, provide new insight into how fat can induce complications after sudden inflammatory, non-infectious illnesses. Doctors have observed that obese people are at greater risk for adverse outcomes after trauma, severe ...

NIH scientists outline steps toward Epstein-Barr virus vaccine

2011-11-03
WHAT: Epstein-Barr virus (EBV) infects nine out of ten people worldwide at some point during their lifetimes. Infections in early childhood often cause no disease symptoms, but people infected during adolescence or young adulthood may develop infectious mononucleosis, a disease characterized by swollen lymph nodes, fever and severe fatigue. EBV also is associated with several kinds of cancer, including Hodgkin lymphoma and stomach and nasal cancers. Organ transplant recipients and people infected with HIV (who become infected with or who already are infected with EBV) ...
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