SEATTLE – A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors still suffer acute graft-versus-host disease (GVHD). The answer appears to lie in the discovery of previously undetected genetic differences in the DNA of patients and unrelated marrow donors. The laboratory-based study findings by Effie Petersdorf, M.D., and colleagues soon will be translated to the clinic when a Hutchinson Center transplant ...

Los Angeles, CA (September 4, 2012) While the effects of sexualized media on young women has long been debated, a new study finds that women who read sex-related magazine articles from popular women's magazines like Cosmopolitan are less likely to view premarital sex as a risky behavior. Additionally, the women who are exposed to these articles are more supportive of sexual behavior that both empowers women and prioritizes their own sexual pleasure. This study was published in a recent article from Psychology of Women Quarterly (published by SAGE). Study authors Janna ...

Might it one day be possible to transmit electricity from an offshore wind turbine to land-based users without any loss of current? Materials known as "high temperature" superconductors (even though they must be maintained at -140°C!), which can conduct electricity without any losses, were supposed to make this dream a reality. But over the past twenty-five years, scientists have not been able to make any progress in this area. Research being done in EPFL's Laboratory for Quantum Magnetism (LQM) could change that. Their study of magnetism at extremely small scales could ...

Released en masse, sterile Mexican fruit flies can undermine a wild population of the fruit-damaging pests so that fewer applications of insecticide are needed. But the irradiation used to sterilize the flies weakens them, hindering their ability to outcompete wild-type males for female mates. Now, U.S. Department of Agriculture (USDA) and collaborating scientists have devised a hormone therapy for making sterile flies "more macho," improving their chances of mating with female flies before their wild rivals do. Peter Teal, a chemist with USDA's Agricultural Research ...

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens understanding of how gene changes may make a child susceptible to this early childhood cancer, as well as causing a tumor to progress. "We discovered common variants in the HACE1 and LIN28B genes that increase the risk of developing neuroblastoma. For LIN28B, these variants also appear to contribute to the tumor's progression once it forms," said ...

Coastline recession The anticipated rise in sea levels due to climate change will result in coastlines receding worldwide through erosion. This is a known phenomenon that can in principle be calculated and predicted based on a given sea-level rise, by means of the so-called Bruun effect. However, things are a little more complicated when it comes to coastlines in the vicinity of inlets, such as river mouths, lagoons and estuaries. These places are affected by other factors, such as changes in rainfall due to climate change, and certain compensating effects (basin infilling). Accurate ...

A lone rooster sees a lot of all the hens in the flock, but the hen with the largest comb gets a bigger dose of sperm - and thus more chicks. This sounds natural, but behind all this is humanity's hunger for eggs. For thousands of years, people have tinkered with the development of domestic chickens. Through selective breeding for a few characteristics such as large muscle mass and increased egg-laying, we have at the same time caused numerous other radical changes in appearance and behaviour. A research group at Linköping University in Sweden has now shown how the size ...

A new fungal species, called 'Hebelomagriseopruinatum', has now officially been included in the list of species. The fungus, whose name can be translated into 'the grey-dewy tear leaf', was discovered on Zealand in Denmark during a mushroom-hunting tour headed by postdoc Jacob Heilman-Clausen from the University of Copenhagen. During a mushroom-hunting excursion in 2009, postdoc Jacob Heilman-Clausen from the Center for Macroecology, Evolution and Climate at the Department of Biology, University of Copenhagen, was handed a very interesting looking fungus. Following ...

Inexperienced psychiatrists are less likely than their veteran peers to accurately predict violence by their patients, but a simple assessment checklist might help bridge that accuracy gap, according to new research from the University of Michigan. Led by psychiatrist Alan Teo, M.D., a Robert Wood Johnson Foundation Clinical Scholar of the University of Michigan, researchers examined how accurate psychiatrists were at predicting assaults by acutely ill patients admitted to psychiatric units. Their results found that inexperienced psychiatric resident doctors did no ...

WCS invests in a diverse array of long term, seascape-scale and species-focused conservation strategies across the waters of 20 countries and all five oceans. We inspire millions to take action for the oceans through the New York Aquarium and all our parks in New York City. To achieve our long-term conservation goals, WCS marine conservationists work with local and national governments, as well as an array of partners to improve management of coastal fisheries, mitigate key threats to marine species, expand effective marine protected areas, enhance ocean industry sustainability, ...

A large meta-analysis conducted by researchers at Moffitt Cancer Center has concluded that breast cancer patients treated with chemotherapy are at risk for mild cognitive deficits after treatment. The meta-analysis, or analytic review of previously published studies, found that study participants on average had mild impairments in verbal abilities (such as difficulty choosing words) and visuospatial abilities (such as getting lost more easily). The study noted that cognitive functioning varies across survivors, with some reporting no impairments and others reporting more ...

1. A*STAR scientists have identified a biomarker of the most lethal form of brain tumours in adults- glioblastoma multiforme. The scientists found that by targeting this biomarker and depleting it with a potential drug, they were able to prevent the progression and relapse of the brain tumour. 2. This research was conducted by scientists at A*STAR's Institute of Medical Biology led by Dr Prabha Sampath, Principal Investigator, in collaboration with A*STAR's Bioinformatics Institute (BII), and clinical collaborators from Medical University of Graz, Austria, and National ...

HOUSTON -- (Sept. 4, 2012) -- In the face of mounting evidence that cancer cells communicate, cooperate and even engage in collective decision-making, biophysicists and cancer researchers at Rice University, Tel Aviv University and Johns Hopkins University are suggesting a new strategy for outsmarting cancer through its own social intelligence. "We need to get beyond the notion that cancer is a random collection of cells running amok," said Herbert Levine, co-director of Rice's Center for Theoretical Biological Physics (CTBP) and co-author of the cover article in this ...

HOUSTON – (Sept. 4, 2012) – Like tiny ships finding port in a storm, carbon atoms dock with the greater island of graphene in a predictable manner. But until recent research by scientists at Rice University, nobody had the tools to make that kind of prediction. Electric current shoots straight across a sheet of defect-free graphene with almost no resistance, a feature that makes the material highly attractive to engineers who would use it in things like touchscreens and other electronics, said Rice theoretical physicist Boris Yakobson. He is co-author of a new paper about ...

Almost three quarters of disposed electrical household appliances in Spain are processed out of the Integrated Waste Management System (SIG). A study at the University of Salamanca exposes how many manufacturers are not registered in the established waste management system and avoid payment. According to the European directive on waste electrical and electronic equipment, manufacturers of such products should recycle the waste they generate during their activity until reaching an annual level of 4 kg per inhabitant. However, in Spain the majority of unused equipment is ...

The governance of Canada's massive Mackenzie River Basin holds enormous national but also global importance due to the watershed's impact on the Arctic Ocean, international migratory birds and climate stability, say experts convening a special forum on the topic. "Relevant parties in western Canada have recognized the need for a multi-party transboundary agreement that will govern land and water management in the Mackenzie River watershed. Successful collaboration will effectively determine the management regime for a watershed covering 1.8 million square kilometers or ...

1. No Nutritional or Safety Differences Between Organic and Conventional Foods There is generally no difference in nutritional value or risk for bacterial contamination between organic and conventional foods, according to a new study being published in Annals of Internal Medicine, the flagship journal of the American College of Physicians (ACP). While the consumption of organic fruits and vegetables reduced exposure to any detectable pesticide residues by 30 percent, pesticide levels were generally within the allowable limits for safety. Researchers conducted a systematic ...

MINNEAPOLIS – People whose blood sugar is on the high end of the normal range may be at greater risk of brain shrinkage that occurs with aging and diseases such as dementia, according to new research published in the September 4, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology. "Numerous studies have shown a link between type 2 diabetes and brain shrinkage and dementia, but we haven't known much about whether people with blood sugar on the high end of normal experience these same effects," said study author Nicolas Cherbuin, ...

STANFORD, Calif. — You're in the supermarket eyeing a basket of sweet, juicy plums. You reach for the conventionally grown stone fruit, then decide to spring the extra $1/pound for its organic cousin. You figure you've just made the healthier decision by choosing the organic product — but new findings from Stanford University cast some doubt on your thinking. "There isn't much difference between organic and conventional foods, if you're an adult and making a decision based solely on your health," said Dena Bravata, MD, MS, the senior author of a paper comparing the nutrition ...

Tigers don't have a reputation for being accommodating, but a new study indicates that the feared and revered carnivores in and around a world-renowned park in Nepal are taking the night shift to better coexist with their human neighbors. The revelation that tigers and people are sharing exactly the same space – such as the same roads and trails – of Chitwan National Park flies in the face of long-held convictions in conservation circles. It also underscores how successful conservation efforts need sciences that takes into account both nature and humans. "As our planet ...

While exchanging favors with others, humans tend to think in terms of tit-for-tat, an assumption easily extended to other animals. As a result, reciprocity is often viewed as a cognitive feat requiring memory, perhaps even calculation. But what if the process is simpler, not only in other animals but in humans as well? Researchers at the Yerkes National Primate Research Center, Emory University, have determined monkeys may gain the advantages of reciprocal exchange of favors without necessarily keeping precise track of past favors. Malini Suchak, a graduate student at ...

STANFORD, Calif. — You already know it's hard to balance your checkbook while simultaneously reflecting on your past. Now, investigators at the Stanford University School of Medicine — having done the equivalent of wire-tapping a hard-to-reach region of the brain — can tell us how this impasse arises. The researchers showed that groups of nerve cells in a structure called the posterior medial cortex, or PMC, are strongly activated during a recall task such as trying to remember whether you had coffee yesterday, but just as strongly suppressed when you're engaged in solving ...

RICHLAND, Wash. -- Combining two well-established analytic techniques and adding a twist identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online. The technique should be able to speed up development of diagnostic tests and treatments based on proteins specific to certain diseases. The team of scientists at the Department of Energy's Pacific Northwest National Laboratory found that their technique, called PRISM, ...

For decades before antibiotics became generally available, sunshine was used to treat tuberculosis, with patients often being sent to Swiss clinics to soak up the sun's healing rays. Now, for the first time scientists have shown how and why heliotherapy might, indeed, have made a difference. A study led by researchers at Queen Mary, University of London, conducted in collaboration with the Medical Research Council's National Institute for Medical Research, has shown that high doses of vitamin D, given in addition to antibiotic treatment, appear to help patients with tuberculosis ...

CHICAGO – Prenatal exposure to maternal cigarette smoking appears associated with an increased risk for adolescent obesity, and is possibly related to subtle structural variations in the brain that create a preference for eating fatty foods, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication. "Prenatal exposure to maternal cigarette smoking is a well-established risk factor for obesity, but the underlying mechanisms are not known," the authors write as background information. "Preference for fatty foods, regulated ...