A new study by rheumatologists at Hospital for Special Surgery in New York has shown that a powerful pro-inflammatory protein, tumor necrosis factor (TNF), can also suppress aspects of inflammation. The researchers say the identification of the mechanism of how this occurs could potentially lead to new treatments for diseases such as rheumatoid arthritis. The study was published May 22 online in advance of publication in the journal Nature Immunology. "Prior to this study, TNF has long been known as a potent pro-inflammatory cytokine, but if you look carefully through ...

Adevarul, Romania's premier integrated multimedia business publishing magazines such as OK!, Forbes, etc. chooses LockLizard Safeguard Enterprise PDF DRM to secure ebooks in their new ebook shop, www.adevarulshop.ro. Adevarul had been looking to provide digital products and take a leading position in the rapidly developing ebook marketplace, but concerns over piracy and associated loss of revenue had prevented them from pursuing this avenue further. Enter LockLizard with their PDF DRM software - a DRM solution for secure ebooks in PDF format. LockLizard PDF DRM has been ...

Researchers have identified a new protein involved in the development of drug resistance in breast cancer which could be a target for new treatments, they report today in the journal Nature Medicine. In a mouse model of breast cancer, blocking production of the protein using genetic techniques caused tumours to shrink. The scientists are now looking for new drugs which could achieve a similar effect. Breast cancer is the most common cancer in the UK, affecting about 46,000 women each year. More than two thirds of breast tumours contain oestrogen receptors, meaning that ...

A new computer model of the Gulf of Mexico in the period after the oil spill provides insights into how underwater currents may have primed marine microorganisms to degrade the oil. "It is called dynamic auto-inoculation. Parcels of water move over the ruptured well, picking up hydrocarbons. When these parcels come back around and cross back over the well, the bacteria have already been activated, are more abundant than before, and degrade hydrocarbons far more quickly," says David Valentine of the University of California, Santa Barbara, speaking today at the 111th ...

Page 1 Solutions, a Colorado-based Internet marketing and website design agency, just launched a new website design and new logo for the company on May 17th, 2011. Page 1 offers Web marketing services to attorneys, dentists, plastic surgeons, and ophthalmologists across the U.S. and Canada. It has been three years since Page 1 has had a new website design and the timing was perfect for the new site to go live. It was launched right before the American Academy of Cosmetic Dentistry (AACD) meeting in Boston, MA, where Page 1 is exhibiting. Spring and summer are busy travel ...

Boston, MA – The physical forces that guide how cells migrate—how they manage to get from place to place in a coordinated fashion inside the living body— are poorly understood. Scientists at the Harvard School of Public Health (HSPH) and the Institute for Bioengineering of Catalonia (IBEC) have, for the first time, devised a way to measure these forces during collective cellular migration. Their surprising conclusion is that the cells fight it out, each pushing and pulling on its neighbors in a chaotic dance, yet together moving cooperatively toward their intended direction. The ...

Boston - A study by researchers at Children's Hospital Boston and collaborators at other institutions has provided new insights into the means by which bone cells produce new bone in response to mechanical stresses, such as exercise. Their findings lay a path for developing new strategies for treating diseases characterized by low bone density, such as osteoporosis in adults and osteogenesis imperfecta in children. The research team, led by Matthew Warman, MD, of the Orthopedic Research Laboratories (ORL) in the Department of Orthopedic Surgery at Children's Hospital ...

The HIV epidemic is the largest in the world and represents one of the most serious public health problems, according to data from the World Health Organization (WHO). Only 30% of the more than 10 million patients in need have the access to the antiretroviral treatment. The total number of infected people exceeds 30 million and there are about 3 million new infections per year. The best hope for reducing the incidence of AIDS (Acquired Immune Deficiency Syndrome) is a preventive vaccine. The most effective preventive vaccines act by inducing a response based on neutralizing ...

Los Angeles, Calif., May 22, 2011—Some men of African descent may have a higher genetic risk of developing prostate cancer, according to research conducted at the Keck School of Medicine of the University of Southern California (USC). The genome-wide association study, published in the journal Nature Genetics on May 22, determined a marker of risk for prostate cancer in men of African descent, who tend to more susceptible to prostate cancer than men of non-African descent. The research team was led by Christopher Haiman, ScD., at the USC Norris Comprehensive Cancer Center ...

STANFORD, Calif. — A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres (protective caps on the ends of chromosomes), can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine. Although dyskeratosis affects only about one in a million people, the scientists' findings could greatly facilitate research into this and other diseases caused by stem cell malfunctions, including some bone marrow failure syndromes and, perhaps, pulmonary ...

A mushroom used in Asia for its medicinal benefits has been found to be 100 per cent effective in suppressing prostate tumour development in mice during early trials, new Queensland University of Technology (QUT) research shows. The compound, polysaccharopeptide (PSP), which is extracted from the 'turkey tail' mushroom, was found to target prostate cancer stem cells and suppress tumour formation in mice, an article written by senior research fellow Dr Patrick Ling in the international scientific journal PLoS ONE said. Dr Ling, from the Australian Prostate Cancer Research ...

BlackjackChamp.com is the leading all inclusive online gambling directory, as well as mobile gambling news and information portal. Blackjack Champ was established to help players find trustworthy and reputable businesses to play real money casino online games on the Internet. For the past 8 years, Blackjack Champ earned the trust and loyalty of thousands of satisfied visitors. The Blackjack Champ brand is respected by both the gaming industry and mainstream media, which acknowledges us as mobile and online gambling industry experts. During the past year, the mobile ...

STANFORD, Calif. — Researchers at Stanford University have developed a special wound dressing that they report was able to significantly reduce scar tissue caused by incisions. Results of animal tests and of an early clinical trial of the dressing were "stunning," said Michael Longaker, MD, MBA, the Deane P. and Louise Mitchell Professor at the School of Medicine and senior author of a study that details the findings. "It was a surprisingly effective treatment." The study will be published online May 23 in the Annals of Surgery. After sutures are removed, the edges ...

A new analysis has found that allowing full access to personal medical records increases satisfaction without increasing anxiety in newly diagnosed cancer patients. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that providing accurate information to patients through medical records can be a beneficial complement to verbal communication with their physicians. Most cancer patients say they are eager to receive comprehensive information about their disease, but many physicians believe that providing it increases ...

NEW ORLEANS, LA – May 23, 2011 -- The next agricultural revolution may be sparked by fungi, helping to greatly increase food-production for the growing needs of the planet without the need for massive amounts of fertilizers according to research presented today at the 111th General Meeting of the American Society for Microbiology in New Orleans. "The United Nations conservatively estimates that by the year 2050 the global human population is expected to reach over 9 billion. Feeding such a population represents an unprecedented challenge since this goes greatly beyond ...

NEW ORLEANS, LA – May 23, 2011 -- As the United States continues to import increasingly more of its food from developing nations, we are putting ourselves at greater risk of foodborne disease as many of these countries do not have the same sanitary standards for production, especially in the case of seafood and fresh produce, say scientists today at the 111th General Meeting of the American Society for Microbiology in New Orleans. "Approximately 15 percent of food consumed in the United States in 2006 was imported. Sanitation practices for food production are not universally ...

Philadelphia, PA, May 23, 2011 – Researchers from the Centers for Disease Control and Prevention (CDC) have examined the potential for human exposure to prion diseases, looking at hunting, venison consumption, and travel to areas in which prion diseases have been reported in animals. Three prion diseases in particular – bovine spongiform encephalopathy (BSE or "Mad Cow Disease"), variant Creutzfeldt-Jakob disease (vCJD), and chronic wasting disease (CWD) – were specified in the investigation. The results of this investigation are published in the June issue of the Journal ...

Another week and another great promotion from RakeTheRake.com to celebrate its new site launch. There's $11,000 worth of prizes to be snapped up, provided by InterPoker and RakeTheRake. InterPoker's very special promotion is one of a wealth of amazing additional prizes running for three months until the end of July 2011. This three month period of extra special poker promotions is over and above the regular $500k+ of monthly promotions at RakeTheRake. InterPoker has put together a great competition over the full three month period. Online poker players at the room have ...

CORAL GABLES, FL (May 23, 2011)-- Economist Christopher Cotton from the University of Miami (UM), uses game theory to explore two of the most famous military bluffs in history. The findings are published in the current issue of the Journal of Peace Research. The study is one of the first to use game theory to assess the Chinese military legends of Li Guang and his 100 horsemen (144 BC), and Zhuge Liang and the Empty City (228 AD). The stories appear in modern day translations of Sun Tzu's fundamental book on military strategy "The Art of War" to explain what is meant ...

JUPITER, FL, May 23, 2011 – Scientists from the Florida campus of The Scripps Research Institute have for the first time accomplished a laboratory synthesis of a rare natural product isolated from the bark of a plant widely employed in traditional medicine. This advance may provide the scientific foundation to develop an effective alternative to commonly prescribed narcotic pain treatments. The study, published May 23, 2011, in an advanced online edition of the journal Nature Chemistry, defines a chemical means to access meaningful quantities of the rare natural product ...

Lombard, IL, May 23, 2011 – Headache is a very common complaint, with over 90% of all persons experiencing a headache at some time in their lives. Headaches commonly are tension-type (TTH) or migraine. They have high socioeconomic impact and can disturb most daily activities. Treatments range from pharmacologic to behavioral interventions. In a study published online today in the Journal of Manipulative and Physiological Therapeutics, a group of Dutch researchers analyzed 119 randomized controlled clinical trials (RCTs) and determined the magnitude of placebo effect and ...

Raleigh criminal attorney Patrick Roberts at the Roberts Law Group PLLC defended a North Carolina man against the statutory rape charges. A man who was caught engaging in sexual acts with a minor by the young woman's mother pled guilty to a misdemeanor in exchange for the dismissal of more serious statutory rape charges. The man pled guilty to contributing to the delinquency of a minor and assault on a female. The man fell prey to a common situation in North Carolina - the alleged victim, a girl under 16 years old, lied about her age on a social networking website. ...

WINSTON-SALEM, N.C. – Monday, May 23, 2011 – New findings out of Wake Forest Baptist Medical Center reveal that a common test may be useful in predicting early death in individuals with diabetes. The study appears in the May issue of Diabetes Care. "People with diabetes are already at high risk of developing heart disease and experiencing an early death," said Donald W. Bowden, Ph.D., the director of the Center for Diabetes Research at Wake Forest Baptist and lead investigator. "With this study, we've discovered that we can identify a subset of individuals within ...

How well a family recovers from a natural catastrophe may be tied to the household's pre-disaster make up and socio-economic status. In a recent study, Dr. Michael Rendall of the RAND Corporation compared the number of households in New Orleans, LA that broke up following Hurricane Katrina to the national rate of household break-ups over an equivalent period. An estimated 1.3 million people fled the Gulf Coast during that emergency in 2005 – the largest urban evacuation America has ever seen. The results are published today in the Journal of Marriage and Family. Relying ...

Jerusalem, May 23, 2011 – A little bitter with a little sweet, in the form of a nano-complex dietary supplement taken before meals, can result in a substantial reduction of fat and sugar absorption in the body, Hebrew University of Jerusalem and Harvard University researchers have found. The researchers previously showed that naringenin, the molecule responsible for the bitter taste in grapefruits, could potentially be used in the treatment of diabetes, arteriosclerosis and hyper-metabolism. However, the absorption of naringenin in its natural form is very low. To ...