Emanuel Petricoin, Co-Director, Center for Applied Proteomics and Molecular Medicine (CAPMM), received funding for the project: “Protein Pathway Activation Based Signaling Mapping of Head And Neck Cancers.” CAPMM researchers will receive laser microdissected tumor samples from banked Formalin-Fixed Paraffin-Embedded (FFPE) clinical biopsy samples from patients with HPV‐positive head and neck cancers who were treated for newly diagnosed disease. The researchers will utilize comprehensive reverse‐phase ...

Emanuela Marasco, Assistant Professor, Center for Secure Information Systems, received funding for the project: “Identity Verification in Smartphones as Social Intersectionality: Inclusive Design of Contactless Fingerprints to Mitigate Skin Tone and Gender Bias.” She is developing a contactless biometric mobile security application that can mitigate the vulnerabilities of deep artificial intelligence and optical sensors and allow marginalized identities the same access to data security.  As part of their work, members of the project team will identify the impact of physical vulnerabilities; their ...

Cancer treatments often cause nerve damage that can lead to long-lasting symptoms. Medication has proven ineffective in these cases. A sports scientist at the University of Basel, together with an interdisciplinary team from Germany, has now shown that simple exercises can prevent nerve damage. Cancer therapies have improved over the years. It is no longer just about sheer survival: quality of life after recovery is gaining more importance. Unfortunately, many cancer medications, from chemotherapy to modern immunotherapies, attack the nerves as well as the tumor cells. Some therapies, such as oxaliplatin or vinca alkaloids, leave 70 to 90 percent of patients complaining of pain, balance ...

New UCSF study shows that suppressing a protein turns ordinary fat into a calorie burner and may explain why drug trials attempting the feat haven’t been successful. Researchers at UC San Francisco have figured out how to turn ordinary white fat cells, which store calories, into beige fat cells that burn calories to maintain body temperature.     The discovery could open the door to developing a new class of weight-loss drugs and may explain why clinical trials of related therapies have ...

Politicians around the world are increasingly mobilizing anti-immigrant sentiment to garner support and votes—a trend that is especially evident as the US presidential election approaches. While political rhetoric that stereotypes and scapegoats immigrants is well-documented, less attention has been given to the impact of these sentiments on immigrants themselves. In an article published today in the Journal of the American Medical Association (JAMA) and in a recently published book, Migration Stigma (MIT Press), scholars identify “migration ...

About The Study: The mortality gap between the U.S. and comparison countries widened in the last decade. Each year, nearly 20,000 deaths among youths ages 0 to 19 years would not have occurred had U.S. youths experienced the median mortality rates of 16 comparison countries. More than half of these deaths involved infants, reflecting disproportionately high U.S. infant mortality rates. Corresponding Author: To contact the corresponding author, Steven H. Woolf, M.D., M.P.H., email steven.woolf@vcuhealth.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2024.1869) Editor’s ...

About The Study: Among live-born infants, first-trimester mRNA COVID-19 vaccine exposure was not associated with an increased risk for selected major structural birth defects in this multisite cohort study. Corresponding Author: To contact the corresponding author, Elyse O. Kharbanda, M.D., M.P.H., email elyse.o.kharbanda@healthpartners.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2024.1917) Editor’s Note: Please see the article for additional ...

With Donald Trump and other right-wing politicians increasingly using dehumanizing rhetoric to stigmatize immigrants coming to our nation's borders, doctors and other health officials should prepare for the resulting health consequences. Such is the message of a “Viewpoint” article co-authored by UC Riverside professor Bruce Link and published Monday, July 1, in the Journal of the American Medical Association. Link and his co-authors quote Trump as saying, “No, they’re not humans. They’re not humans. They’re ...

State-of-the-art prosthetic limbs can help people with amputations achieve a natural walking gait, but they don’t give the user full neural control over the limb. Instead, they rely on robotic sensors and controllers that move the limb using predefined gait algorithms. Using a new type of surgical intervention and neuroprosthetic interface, MIT researchers, in collaboration with colleagues from Brigham and Women’s Hospital, have shown that a natural walking gait is achievable using a prosthetic leg fully driven by the body’s own nervous system. ...

The earlier a cancer is detected, the better the chances that treatment will be effective. This applies to almost all types of cancer. Another crucial element in successfully treating patients is to individually assess the benefits and risks of individual forms of therapy and to regularly monitor treatment success. To do this, oncologists have a range of methods at their disposal, most notably imaging technology and invasive measures such as tissue biopsies, punctures and endoscopic procedures. Analyzing gene fragments in the bloodstream Researchers ...

Korea University's College of Medicine (Dean Pyun, Sung Bom) hosted the 1st Research Nexus Program in order to enhance international research network cooperation and vitalize global joint research.   This program shares the latest research trends and aims to invigorate international joint research by opening a seminar inviting top global scholars to promote international research performances.   The 1st program held an invitation seminar of Prof. Jeffrey D. Macklis, the "global authority in the field of neurogenesis" (Department of Stem Cell and Regenerative Biology at Harvard University).   Prof. Macklis ...

A study at Umeå University, Sweden, provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics. "You could say that we are adding a piece of the puzzle to the understanding of how antibiotic resistance spreads between bacteria," says Ronnie Berntsson, Associate Professor at Umeå University and one of the authors behind the study. The Umeå researchers have studied Enterococcus faecalis, which is a bacterium that often ...

The debate has raged for decades: Was it humans or climate change that led to the extinction of many species of large mammals, birds, and reptiles that have disappeared from Earth over the past 50,000 years? By "large," we mean animals that weighed at least 45 kilograms – known as megafauna. At least 161 species of mammals were driven to extinction during this period. This number is based on the remains found so far. The largest of them were hit the hardest – land-dwelling herbivores weighing over a ton, the megaherbivores. Fifty thousand years ago, there were 57 species of megaherbivores. Today, only 11 remain. These remaining ...

Analyzing nasal swabs taken during the pandemic, researchers at Yale School of Medicine suggest that the frequent presence of other viruses and bacteria may have helped to protect children from the worst effects of COVID-19 by boosting their immune systems. Their results will be published July 1 in the Journal of Experimental Medicine (JEM). Children are generally more susceptible than adults to respiratory infections such as the common cold, and yet, for unknown reasons, the SARS-CoV-2 virus tends to cause less severe ...

BATON ROUGE, La. – Ochsner Medical Center – Baton Rouge now offers robotic-assisted bronchoscopy using the Ion robotic platform, a new, minimally invasive option for lung biopsy. With bronchoscopy, doctors insert a long, thin tube with a camera to examine lung tissue and retrieve a biopsy sample. The Ion robot enables doctors to perform a biopsy quicker and safer than ever before. These advancements are especially critical for treating lung cancer, since early detection is key to achieving the best outcome. Every six weeks of delayed treatment lowers ...

Chicago (July 1, 2024) — New research performed with mice suggests that daily time in a warm environment such as a sauna might help older adults, especially women, combat age-related obesity and insulin resistance. The study shows the potential of heat treatments as a simple way to promote healthier aging. The researchers found that older female mice receiving a daily 30-minute whole-body heat treatment gained less weight and showed improved use of insulin, which helps control blood sugar. The investigators ...

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics. One such bacterium is Pseudomonas aeruginosa, which is naturally found in soil and water, but also hospitals, nursing homes and similar institutions for persons with weakened immune systems are home for strains of this bacterium. As many P. Aeruginosa strains found in hospitals are resistant to most antibiotics in use, science is forced to constantly search for new ways to kill them.   Now, at team of researchers from Department of Biochemistry and Molecular Biology and Department of ...

Not everything in the brain is meant to last. As our brains assemble, trillions of neural connections have to be built or torn down at the right time and place. Otherwise, the seeds of disorders like autism can take root. Cold Spring Harbor Laboratory Assistant Professor Gabrielle Pouchelon studies how the brain is wired early in life. In doing so, she hopes to find the origins of various brain dysfunctions and new ways to treat them. In a new study, Pouchelon and her team zero in on a process known as pruning. This is when the brain removes unnecessary connections between ...

DALLAS, July 1, 2024 — The American Heart Association, celebrating 100 years of lifesaving service as the world’s leading nonprofit organization focused on heart and brain health for all, has named its volunteer leadership for fiscal year 2024-25. Keith Churchwell, M.D., FAHA, serving as the new volunteer president, and Marsha Jones, continuing a two-year term as volunteer board chairperson, will help guide the Association as it enters its second century. Churchwell and Jones are long-time volunteer leaders for ...

FOR IMMEDIATE RELEASE 1 July 2024 The Geological Society of America Release No. 24-06 Contact: Jason Elkins +1-303-357-1026 jelkins@geosociety.org Boulder, Colo., USA: The Geological Society of America (GSA) is excited to announce a significant reduction in membership fees for students. Effective 1 July 2024, undergraduate and graduate students majoring in geology or related sciences can sign up for an annual student membership for just $25. This initiative underscores GSA's commitment to supporting the next generation of geoscientists by making membership more accessible and affordable. The ...

Every year, the negative effects of human activities on the environment become increasingly clear. From climate change and microplastics to the endangerment and extinction of countless species, it is evident that we need to find new ways to achieve sustainability. Fortunately, many research groups in prominent fields like chemistry and materials science are tirelessly working to develop solutions to get us closer to circular and sustainable economies. One area that has attracted much attention in this regard is biomass upcycling. It refers to the transformation of naturally available organic materials into ...

Pioneering AI-powered research on butterflies has probed the under-studied evolution of females and adds to a debate between the founding fathers of evolution. The University of Essex study – published in Communications Biology – explores a controversy between Victorian scientists Charles Darwin and Alfred Russel Wallace. Darwin thought males had more variation, as females often chose mates based on male appearance. Whereas Wallace thought natural selection across sexes was the biggest factor in difference. For over a century, scientists ...

Our bodies are inhabited by trillions of microorganisms, with specific microbes unique to each individual. Through experimentation, scientists have pinpointed certain factors that account for variation in the gut: diet, living conditions, exercise and maternal line. Now, scientists at University of California San Diego have discovered another factor that affects the composition of the gut microbiome: time of day. In fact, the scientists have found that time of day is such an important factor that they’re calling on the National Institutes of Health (NIH) to require researchers ...

Researchers at Karolinska Institutet in Sweden have developed nanorobots that kill cancer cells in mice. The robot’s weapon is hidden in a nanostructure and is exposed only in the tumour microenvironment, sparing healthy cells. The study is published in the journal Nature Nanotechnology. The research group at Karolinska Institutet has previously developed structures that can organise so-called death receptors on the surface of cells, leading to cell death. The structures exhibit six peptides (amino acid chains) assembled in a hexagonal pattern. “This hexagonal nanopattern of peptides becomes a lethal weapon,” explains Professor ...

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found. Other genes can directly affect age of puberty, some with profound effects. In the largest study of its kind to date, an international team led by researchers at the Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, studied the DNA of around 800,000 women from Europe, North America, China, Japan, and Korea. Published today in Nature Genetics, the researchers found more than 1,000 variants – small changes in DNA – that ...