Use of a patient's bone marrow cells for treating chronic ischemic heart failure did not result in improvement on most measures of heart function, according to a study appearing in JAMA. The study is being published early online to coincide with its presentation at the American College of Cardiology's annual scientific sessions. Cell therapy has emerged as an innovative approach for treating patients with advanced ischemic heart disease, including those with heart failure. "In patients with ischemic heart disease and heart failure, treatment with autologous [derived from ...

CHICAGO— Cell therapy may present an option for patients with ischemic heart disease to use their own bone marrow cells to repair the damaged areas of their hearts, and may pave the way for future treatment options, according to the FOCUS trial, which will be presented as a late-breaking clinical trial March 24 at the 61st annual American College of Cardiology (ACC) scientific session. This is the largest study to date to look at stem cell therapy, using a patient's own stem cells, to repair damaged areas of the heart in patients with chronic ischemic heart disease and ...

CHICAGO – Researchers from Thomas Jefferson University Hospital discovered that blockages in the right coronary artery and those in bending areas of the coronary artery are the most common places for dissection, a tear in the artery that can occur during balloon angioplasty of the coronary arteries. They will present their findings at the American College of Cardiology annual meeting in Chicago on Saturday, March 24 at 9 AM. A 'controlled tear' is the mechanism by which angioplasty dilates the blocked vessels. A large tear, or spiral dissection, that continues ...

SAN DIEGO, March 25, 2012 — Popcorn's reputation as a snack food that's actually good for health popped up a few notches today as scientists reported that it contains more of the healthful antioxidant substances called "polyphenols" than fruits and vegetables. They spoke at the 243rd National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society, being held here this week. Joe Vinson, Ph.D., a pioneer in analyzing healthful components in chocolate, nuts and other common foods, explained that the polyphenols are more concentrated ...

SAN DIEGO, March 25, 2012 — Scientists are enlisting the living, self-propelled microbes found in pond scum — the pea-green surface slicks that form on ponds — in the development of a long-awaited new test to detect the cells that spread cancer through the bloodstream from the original tumor to new sites in the body. In a report here today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society, they described how the test is intended to not only identify the spreading of cells, but allow lab analysis of ...

SAN DIEGO, March 25, 2012 — A preservative in toothpastes, hand soaps, underarm deodorants and other everyday products is getting a second life, helping crime scene investigators preserve evidence of arson, scientists reported here today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS). The preservative, triclosan, would be the first evidence preservative for traces of gasoline and other ignitable fluids, or flame "accelerants," commonly used in arson, according to John V. Goodpaster, Ph.D., an international expert who reported on evidence ...

SAN DIEGO, March 25, 2012 — The long-sought technology for enabling the fabled "hydrogen economy" — an era based on hydrogen fuel that replaces gasoline, diesel and other fossil fuels, easing concerns about foreign oil and air pollution — has been available for decades and could begin commercial production of hydrogen in this decade, a scientist reported here today. Speaking at the 243rd National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society, Ibrahim Khamis, Ph.D., described how heat from existing nuclear plants could ...

SAN DIEGO, March 25, 2012 —Just as aspiring authors often read hundreds of books before starting their own, scientists are using decades of knowledge garnered from sequencing or "reading" the genetic codes of thousands of living things to now start writing new volumes in the library of life. J. Craig Venter, Ph.D., one of the most renowned of those scientists, described the construction of the first synthetic cell and many new applications of this work today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific ...

SAN DIEGO, March 25, 2012 — Medicine's recipe for keeping older people active and functioning in their homes and workplaces — and healing younger people injured in catastrophic accidents — may include "noodle gels" and other lab-made invisible filaments that resemble uncooked spaghetti with nanoscale dimensions, a scientist said here today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS). The world's largest scientific society, ACS is meeting here this week with reports on more than 11,000 reports on new advances in science on its schedule. Samuel ...

SAN DIEGO, March 25, 2012 — Bassam Z. Shakhashiri, Ph.D., president of the American Chemical Society (ACS) — the world's largest scientific society — today described initiatives on climate science, the education of future scientists and commemoration of a landmark federal law that engendered some of the nation's greatest universities. Those initiatives will be the theme of Shakhashiri's presidential year. A chemistry professor who holds the William T. Evjue Distinguished Chair for the Wisconsin Idea at the University of Wisconsin-Madison, Shakhashiri discussed the projects ...

SAN DIEGO, March 25, 2012 — Combining the secrets that enable water striders to walk on water and give wood its lightness and great strength has yielded an amazing new material so buoyant that, in everyday terms, a boat made from 1 pound of the substance could carry five kitchen refrigerators, about 1,000 pounds. One of the lightest solid substances in the world, which is also sustainable, it was among the topics of a symposium here today at the 243rd National Meeting & Exposition of the American Chemical Society, the world's largest scientific society. The symposium ...

A new interventional radiology treatment, prostatic artery embolization, may bring hope to men with debilitating symptoms caused by an enlarged prostate, say the group of researchers who pioneered its use. The findings were presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif. "Having an enlarged prostate is very common in many men over the age of 50, and these new findings provide hope for those who might not be candidates for transurethral resection of the prostate, or TURP—and may allow them to avoid serious ...

Researchers who investigated the connection between chronic cerebrospinal venous insufficiency (a reported condition characterized as a blockage in the veins that drain blood from the brain and spinal cord and returns it to the heart) and multiple sclerosis indicate that a minimally invasive endovascular treatment for CCSVI, is safe and may produce "significant," short-term improvement in physical- and mental health-related quality of life in individuals with MS. These findings were presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in ...

Researchers report that performing angioplasty (a treatment that involves temporarily inserting and blowing up a tiny balloon inside a clogged artery to help widen it) on veins in the neck and chest is safe—and may be an effective way to treat the venous abnormalities found in those with multiple sclerosis and provide symptom relief. The findings were presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif. "Our results are important because there are an estimated 400,000 individuals affected by multiple sclerosis ...

New guidelines for CT-guided biopsies of lung nodules significantly reduce radiation exposure allowing individuals the benefit of the procedure, which may cut down on overall lung cancer deaths. This research is being presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif. "The published early results of a trial using computed tomography to detect lung nodules demonstrated that screening with low-dose CT reduced mortality from lung cancer by 20 percent compared to screening with chest X-rays alone," said Jeremy Collins, ...

A burst aneurysm (a local area of bulge) in the abdominal aorta—the largest blood vessel in the body— is a deadly condition. In fact, about half of these patients don't make it to the hospital in time. Those who do more often than not face open surgery to repair the blood vessel. This study finds that a minimally invasive interventional radiology treatment for ruptured aneurysms called endovascular aneurysm repair (EVAR) is safer than open surgical repair and is associated with lower mortality rates, say researchers Society of Interventional Radiology's 37th Annual Scientific ...

KANSAS CITY, MO—Few molecules are more interesting than DNA—except of course RNA. After two decades of research, that "other macromolecule" is no longer considered a mere messenger between glamorous DNA and protein-synthesizing machines. We now know that RNA has been leading a secret life, regulating gene expression and partnering with proteins to form catalytic ribonucleoprotein (RNP) complexes. One of those RNPs is telomerase, an enzyme that maintains chromosome integrity. In the March 25, 2012, advance online edition of Nature, researchers at the Stowers Institute ...

A genetic finding could help explain why influenza becomes a life-threating disease to some people while it has only mild effects in others. New research led by the Wellcome Trust Sanger Institute has identified for the first time a human gene that influences how we respond to influenza infection. People who carry a particular variant of a gene called IFITM3 are significantly more likely to be hospitalised when they fall ill with influenza than those who carry other variants, the team found. This gene plays a critical role in protecting the body against infection with ...

The ripeness of fruit could determine how food-poisoning bacteria grow on them, according to scientists presenting their work at the Society for General Microbiology's Spring Conference in Dublin this week. Their work could lead to new strategies to improve food safety, bringing many health and economic benefits. A wide range of fresh produce has been linked to outbreaks of Escherichia coli and Salmonella enterica including melons, jalapeño and serrano peppers, basil, lettuce, horseradish sprouts and tomatoes. Researchers at Imperial College London are looking at how ...

Henderson Properties, a full service real estate company, last week, celebrated the opening of its Union County office in Indian Trail with a ribbon cutting and business networking event in conjunction with the Union County Chamber. The office, located at 4389 Indian Trail-Fairview Road, is the company's fourth branch location. Henderson Properties also has offices in South Charlotte, Lake Norman and Fort Mill. The new office allows Henderson Properties real estate agents to better serve Union County residents. In attendance was Kara Disotell, manager of Henderson ...

Wall Templeton & Haldrup, P. A. (www.WallTempleton.com), is pleased to announce Tommy Boger has joined the firm's Charleston office as an associate attorney. A graduate of Clemson University and the Charleston School of Law, Boger will focus his practice in the areas of complex litigation, construction, and commercial litigation. Prior to attending law school, Boger worked in the mortgage industry as an online marketing manager and a loan consultant, originating residential mortgage loans in Columbia and Charleston, SC. He is a member of the South Carolina Bar and ...

Oral bacteria that escape into the bloodstream are able to cause blood clots and trigger life-threatening endocarditis. Further research could lead to new drugs to tackle infective heart disease, say scientists presenting their work at the Society for General Microbiology's Spring Conference in Dublin this week. Streptococcus gordonii is a normal inhabitant of the mouth and contributes to plaque that forms on the surface of teeth. If these bacteria enter into the blood stream through bleeding gums they can start to wreak havoc by masquerading as human proteins. Researchers ...

Viruses that can target and destroy bacteria have the potential to be an effective strategy for tackling hard-to-treat bacterial infections. The development of such novel therapies is being accelerated in response to growing antibiotic resistance, says Dr David Harper at the Society for General Microbiology's Spring Conference in Dublin. Bacteriophages are viruses that can infect bacteria and multiply within them, breaking down the cell and destroying the bacteria - amplifying themselves in the process to deal with more bacteria. They are found everywhere including in ...

In a report published in recent weeks, Technology Evaluation Centers (TEC) announced that The Answer Company is the newest recipient of its Accreditation for Enterprise Resource Planning (ERP) Providers. The Answer Company, with offices in Vancouver, Calgary and Toronto, is the first ERP reseller in Western Canada to receive the rigorous TEC Accreditation, demonstrating its commitment to show prospective and existing clientele that users of the company's solutions are confident in the abilities and services. Recent emphasis on the high failure rate of software implementations, ...

UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. Published March 25 online in Nature Medicine, the team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae. Dendritic cells, like scouts in the field of a military operation, deliver key information about an invading pathogen that helps activate the T-cells in launching a more effective attack. It ...