Fasthosts has revealed that British web designers continue to face tough market conditions, according to recently conducted research. The study of 300 web design firms* by Fasthosts, a leading web hosting provider, finds that whilst 72 per cent have seen an increase in expectations from their SME clients, the majority are struggling with lower budgets and under-cutting by cut-price competitors. 71 per cent of web designers believe that insufficient investment is holding back SME websites. In the past two years, 1 in 3 web pros have been expected to supply more out-of-hours ...

KLAS today released the "2010 Top 20 Best in KLAS Awards: Software & Professional Services" report. The report includes the annual rankings of the best-performing healthcare IT vendors based on more than 17,000 interviews conducted yearly with healthcare providers. KLAS rankings measure a vendor's performance in areas of product quality, implementation, and service and support. The top-rated companies in key market categories earned the 2010 Best in KLAS distinction, signifying their leadership in meeting customer expectations. The award is reserved for companies in ...

H. Ross Ford, president and CEO of TCN Worldwide, has announced the appointment of David Greene, president of the commercial brokerage division of Murray Hill Properties/TCN Worldwide in New York City, to the Board of Directors for 2011. "We are very pleased to announce David Greene as a TCN Worldwide Board Member," stated H. Ross Ford. "David's impressive background, stellar reputation within the industry and his continued commitment to both Murray Hill Properties as well as our organization has made him an ideal candidate to serve as a member of our Board of Directors. ...

The holiday season is upon us, and many of us are still on that frantic search for the perfect gift for that special someone. If that certain someone happens to hold a place in their heart for a good poker game, MyPokerBasics.com may just have some good ideas for you. MyPokerBasics.com is a leading authority in the online poker industry, delivering a throng of resources for online poker players. The internet gaming guide is proud to announce a vast expansion in its content offerings just in time for Christmas. The expansion includes the provision of daily poker news, ...

Gridiron Fulfillment, a leading fulfillment warehousing company, has adopted new RFID technology that combines enhanced efficiency and communication with significantly lower costs for its customers. Gridiron manages the fulfillment needs of many businesses simultaneously and each of its customers looks to Gridiron for speed, accuracy and cost-effectiveness. While many fulfillment services continue to rely on spreadsheets for managing inventory and email for communicating with customers, Gridiron has committed to Radio Frequency Identification (RFID) technology throughout ...

PokerNews.com has been expanding their content offerings in order to provide more information and better value to their readers. Some of the new additions to the site are top list pages that are geared towards specific groups, such as players from different countries or players looking for specific information on things such as mobile poker and bad beat jackpots. In addition to the new top list pages, the PokerNews.com team has been busy improving their PokerNews Strategy section, continuing to build upon the success of their staking site ChipMeUp, and offering new online ...

Thomas, 36, began soccer at the age of 4 and played professionally until the age of 30 before succumbing to chronic knee problems. Thomas by sharing his talent and dedication to excellence with his readers, hopes to encourage his followers to excel in soccer through hard work, commitment, discipline and love. "I invite all soccer players, coaches and parents - especially kids and teens - to join me at www.soccermastermind.com and witness first hand the power of Love Based Soccer." "You can't deny the passion, power and excitement of Love Based Soccer," said Thomas. Karapatsos ...

Thursday, December the 16th, will be a very unique day at the Washington offices of the USCIS. People waiting in long lines at the U.S. immigration office (USCIS) in Washington D.C. will receive a special Christmas present: a 5-hour DVD explaining every single visa and Green Card along with tips and secrets to making the American dream come true. The thought is that people waiting in lines cannot afford a lawyer and need the information the most, as the system is complex and can be daunting with permanent consequences. Dallas-based US immigration expert Steven Riznyk ...

Qsan Technology is announcing that all models (P300Q, P500Q, F300Q, S300Q) in Q series have been certified for Windows Server 2008 R2, Windows Server 2008 32- and 64-bit, Windows Server 2003 R2 32- and 64-bit from Microsoft's Windows Hardware Quality Labs (WHQL). This is Qsan's commitment to our customers that it's a never-ending quest to pursue upmost quality, reliability and performance. We can offer you a full range of storage solutions from 10Gb iSCSI, 1Gb iSCSI, 4Gb Fibre Channel to 6Gb SAS direct attached system. With WHQL certification in place, it ensures that our ...

Virtual Simulations Inc. is pleased to announce the establishment of a new business partnership with Remograph AB in which it will become a distributor of Remograph's Remo 3D modeling / CAD software for the north, center and South American regions. Remo 3D is a powerful, yet aggressively priced 3D modeling CAD software that represents a new milestone toward making virtual world authoring accessible for all types of businesses. The pricing scheme of Remo 3D makes it possible to equip large development teams with multiple licenses in a way that is not possible with competing ...

Researchers at Emory University School of Medicine and the University of Chicago have developed a method for labeling and mapping a "sixth nucleotide," whose biological role scientists are only beginning to explore. The method is described online this week in Nature Biotechnology. The method allowed the researchers to see for the first time how 5-hydroxymethylcytosine (5-hmC) is distributed throughout the genome. Unlike 5-methylcytosine (5-mC), a chemical modification of DNA that is generally found on genes that are turned off, this extra layer of modification is enriched ...

The protozoan parasite Toxoplasma gondii and the pathogenic bacterium Chlamydia trachomatis exemplify convergent evolution, the development of a similar biological trait in unrelated lineages, according to research presented today at the American Society of Cell Biology's 50th Annual Meeting in Philadelphia. The biological trait shared by the two pathogens is their modus operandi – how they operate inside human host cells to reproduce themselves, said scientists at the Johns Hopkins Bloomberg School of Public Health, working with researchers at the University of Maryland ...

Cultured mesenchymal stem cells can "feel" at least several microns below the surface of an artificial microfilm matrix, gauging the elasticity of the extracellular bedding that is a crucial variable in determining their fate, researchers reported today at the American Society for Cell Biology's 50th Annual Meeting in Philadelphia. Controlling or predicting how stem cells differentiate into cells of a specific tissue type is a critical issue in the bioengineering of artificial tissue and in stem cell medicine. To determine how deep a cell's sense of touch can reach, ...

Deleting the receptor, not the protein ghrelin itself, turns up the body's fat-burning thermostat, giving aging mice an exothermic boost toward a svelte physique, researchers reported at the American Society of Cell Biology's 50th Annual Meeting in Philadelphia. The protein's receptor, growth hormone secretagogue receptor (GHS-R), might make a better target than ghrelin for treating obesity, according to Yuxiang Sun, M.D., Ph.D., of the Baylor College of Medicine in Houston, TX. Sun said that experimentally deleting the receptor from the body cells of laboratory mice ...

Long considered a freewheeling loner, the Trypanosoma brucei parasite responsible for African sleeping sickness has revealed a totally unexpected social side, opening a potential chink in the behavioral armor of this and other supposedly solitary human parasites, according to research presented at the American Society for Cell Biology's 50th Annual Meeting in Philadelphia. "The concept of bacteria acting as groups of cells communicating and cooperating with one another has had a major impact on our understanding of bacterial physiology and pathogenesis, but this paradigm ...

Small details between "in vivo" and "in vitro" studies make for big differences in understanding diabetes and other secretory dysfunctions Exocytosis, the fundamental process by which cells secrete hormones such as insulin and other useful biological substances, is regulated far differently in life than in laboratory tissue cultures and explanted organs, according to research presented today at the American Society of Cell Biology's 50th Annual Meeting in Philadelphia. The unexpected findings that exocytosis regulation "in vivo" is not the same as the process long studied ...

Researchers have provided the first thorough mechanistic account of how a genetic defect leads to malignant hypothermia (MH) and central core disease (CCD), rare genetic skeletal muscle disorders. The study appears in the January issue of the Journal of General Physiology (www.jgp.org). Mutations in the type 1 ryanodine receptor (RYR1), the calcium release channel of the sarcoplasmic reticulum (SR) activated during skeletal muscle excitation-contraction (EC) coupling, give rise to CCD. One of the most common CCD-causing mutations is Ile4895Thr. Now, Robert Dirksen (University ...

ST. PAUL, Minn. – Many people with incurable brain tumors use alternative therapies, such as taking vitamins and homeopathy, in addition to their conventional treatments, according to a study published in the December 14, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology. About 40 percent of brain tumor patients in the study used alternative therapies including homeopathic remedies, vitamin supplements and psychological therapy. "The use of these alternative treatments may be largely overlooked and underestimated," said study ...

Folic acid can reduce birth defects including neural tube defects, congenital heart disease and oral clefts but some speculate high intakes of folic acid may be associated with adverse events such as colorectal cancer, states an article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100568.pdf. This study, conducted by researchers at Children's Hospital of Eastern Ontario Research Institute and The Hospital for Sick Children, is the first of its kind in more than three decades, to examine the folate status of Canadians ...

Disease-management programs, which may include patient education, psychological intervention, dietary education, self-monitoring and telemedicine, can improve diabetes care, states an article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj091786.pdf. The study, by French researchers, included 41 randomized controlled trials published between 1990 and 2009 with a total of 7013 patients. The findings showed that disease-management programs are more effective than usual care in reducing glycated hemoglobin levels ...

VIDEO: This movie spotlights one waggle dance by a forager that had been sleep-deprived the previous night. The average dance angle of this dance is superimposed over the dancer and variance around... Click here for more information. AUSTIN, Texas—In the busy world of a honey bee hive, worker bees need their rest in order to best communicate the location of food to their hive mates, research from The University of Texas at Austin shows. "When deprived of sleep, humans ...

SAN ANTONIO, Texas, U.S.A. (Dec. 13, 2010) — Scientists at the UT Health Science Center San Antonio restored learning and memory in an Alzheimer's disease mouse model by increasing a protein called CBP. Salvatore Oddo, Ph.D., of the university's Department of Physiology and Barshop Institute for Longevity and Aging Studies, said this is the first proof that boosting CBP, which triggers the production of other proteins essential to creating memories, can reverse Alzheimer's effects. The finding, reported this week in Proceedings of the National Academy of Sciences, provides ...

Boston, Mass. – It's widely recognized that fragmentation of medical information is a problem in health care, but the extent of the problem and how many patients may be at risk haven't been well quantified. In a new retrospective study, researchers at Children's Hospital Boston looked at adult acute care in Massachusetts and found that of 3.6 million adults visiting an acute care site during a five-year period, almost a third sought care at two or more different hospitals. These patients accounted for more than half of all acute care visits in the state, as well as more ...

The number of people with asthma has increased sharply over the past few decades. It has been suggested that this is a result of decreased childhood exposure to microorganisms. A team of researchers — led by Dale Umetsu, at Harvard Medical School, Boston; Michio Shimamura, at the University of Tsukuba, Japan; and Petr Illarionov, at the University of Birmingham, United Kingdom — has now provided concrete evidence in mice to support this idea and identified an underlying mechanism to explain this protection, which the team hope could be exploited to develop ways to prevent ...

Chronic myeloid leukemia (CML) was transformed from a fatal disease to a chronic condition by the development of a drug known as imatinib, which targets the protein that drives this disease (BCR-ABL). However, imatinib does not cure patients, they must take the drug lifelong, as disease recurs if they stop taking it. This is because imatinib does not kill all the CML cells; some, which are known as CML stem cells, persist. A key to therapeutically targeting CML stem cells is knowing whether they rely on BCR-ABL to persist. Answers to this will determine whether more effective ...