Case Western Reserve University School of Medicine and Athersys, Inc. (NASDAQ: ATHX) announced a joint scientific study on spinal cord injury will be published today in the January issue of the Journal of Neuroscience. The study, by leading researchers from the Department of Neurosciences at the School of Medicine and scientists at Athersys, presents data supporting the potential therapeutic benefit of Athersys' MultiStem® program for spinal cord injury. Researchers observed that administration of Multipotent Adult Progenitor Cells (MAPC) following spinal cord injury in ...

PASADENA, Calif.—Using a common metal most famously found in self-cleaning ovens, Sossina Haile hopes to change our energy future. The metal is cerium oxide—or ceria—and it is the centerpiece of a promising new technology developed by Haile and her colleagues that concentrates solar energy and uses it to efficiently convert carbon dioxide and water into fuels. Solar energy has long been touted as the solution to our energy woes, but while it is plentiful and free, it can't be bottled up and transported from sunny locations to the drearier—but more energy-hungry—parts ...

Australian scientists using new image and cell technologies have for the first time caught malaria parasites in the act of invading red blood cells. The researchers, from the Walter and Eliza Hall Institute in Melbourne, Australia, and the University of Technology, Sydney (UTS), achieved this long-held aim using a combination of electron, light and super resolution microscopy, a technology platform new to Australia. The detailed look at what occurs as the parasite burrows through the walls of red blood cells provides new insights into the molecular and cellular events ...

A University of British Columbia study shows that there are enough pharmacies situated throughout Ontario communities to absorb many closures without negatively affecting geographical accessibility for residents. The research suggests concerns that reducing generic pricing could result in pharmacy shortages are unfounded. Last summer, the Ontario government cut the price of generic drugs by half – to approximately 25 per cent of the equivalent brand – leading to heated discussions on the sustainability of existing pharmacies. Some pharmacy chains claimed they might be ...

An International research team has discovered that seasonal temperatures in Europe, above all in winter, have been affected over the past 500 years by natural factors such as volcanic eruptions and solar activity, and by human activities such as the emission of greenhouse gases. The study, with Spanish involvement, could help us to better understand the dynamics of climate change. Up until now, it was thought that Europe's climate prior to 1900 was barely affected by external factors, but now a group of scientists has shown that natural phenomena such as volcanic eruptions ...

The study, published in the Journal of Clinical Investigation, reveals that damaged alpha-synuclein proteins (which are implicated in Parkinson's disease) can spread in a 'prion-like' manner, an infection model previously described for diseases such as BSE (mad cow disease). "This is a significant step forward in our understanding of the potential role of cell-to-cell transfer of alpha-synuclein in Parkinson's disease pathogenesis and we are very excited about the findings", says Professor Patrik Brundin at Lund University, Sweden, who led a team of investigators from ...

Researchers at Neiker-Tecnalia (the Basque Institute for Agricultural Research and Development) have undertaken a study on the epidemiology and diagnosis of infection by visna/maedi virus. This is a virus that affects sheep herds causing chronic interstitial pneumonia, mastitis and neurological disorders. The study confirmed that horizontal transmission (direct contact between infected animals) of the virus is the most likely path of infection, rather than vertical transmission (from infected suckling milk or colostrum). Since there is no current effective treatment against ...

The research team at the Centre for the Studies of Archaeological and Prehistoric Heritage (CEPAP) of Universitat Autònoma de Barcelona (UAB) have implemented an innovative system to register archaeological artefacts which eliminates problems in manual markings, such as errors in writing or erosion of data. The system, based on direct labelling using bi-dimensional data matrix (DM) codes, has been used by the CEPAP team during two years, in which numerous artefacts and bone remains from sites in Spain and Africa were registered. The marking of archaeological material, ...

Tel Aviv -- Although we're convinced that baby is brilliant when she mutters her first words, cognitive scientists have been conducting a decades-long debate about whether or not human beings actually "learn" language. Most theoretical linguists, including the noted researcher Noam Chomsky, argue that people have little more than a "language organ" -- an inherent capacity for language that's activated during early childhood. On the other hand, researchers like Dr. Roni Katzir of Tel Aviv University's Department of Linguistics insist that what humans can actually learn ...

Associate professor Anne Mangen at the University of Stavanger's Reading Centre asks if something is lost in switching from book to computer screen, and from pen to keyboard. The process of reading and writing involves a number of senses, she explains. When writing by hand, our brain receives feedback from our motor actions, together with the sensation of touching a pencil and paper. These kinds of feedback is significantly different from those we receive when touching and typing on a keyboard. Learning by doing Together with neurophysiologist Jean-Luc Velay at the ...

Malignant gliomas are fast-growing brain tumours with poor prospects of recovery depending on disease stage. Experts hope that the examination of patients by means of positron emission tomography (PET) is more helpful in the choice of the right treatment than other procedures. In a final report the German Institute for Quality and Efficiency in Health Care (IQWiG) has now investigated the benefit of PET in the detection of recurrences. According to this report, no robust conclusions are possible on the advantages or disadvantages of PET. Two research questions investigated The ...

Recent work, in particular the CAMERA study, has used MRI to study the brains of migraine sufferers and has shown that a higher proportion of these patients exhibit lesions of the brain microvessels than the rest of the population. Lesions of the brain microvessels Lesions of the brain microvessels, visible on cerebral MRI images, can be of various kinds: white-matter hyperintensities and, more rarely, silent infarcts leading to loss of white-matter tissue. They result from a deterioration of the small cerebral arteries that supply blood to the brain's white matter, ...

Fairfax, Va., January 18, 2011 – HIV-positive head and neck cancer patients respond well to radiation therapy treatments and experience similar toxicity rates as non-HIV-positive patients, despite prior reports to the contrary, according to a study in the January issue of the International Journal of Radiation Oncology•Biology•Physics, an official journal of the American Society for Radiation Oncology (ASTRO). Patients with HIV have a significantly higher risk of developing some types of cancers; however, since the use of highly active antiretroviral therapy (HAART) began ...

In birds as in humans, female fertility declines with age. But some female birds can slow the ticking of their biological clocks by choosing the right mates, according to results of a study published online last week in the journal Oikos. Female birds become progressively less fertile as age takes its toll, says biologist Josh Auld of the National Evolutionary Synthesis Center in Durham, North Carolina, and co-author of the Oikos paper. Older females lay fewer eggs, and they lay them later in the season--at a time when less food is available for their chicks. But ...

DETROIT— The combined results of a genetic blood test and a five-minute functional MRI successfully classified more than three-quarters of healthy older adults, many of whom were destined to develop cognitive decline within 18 months of testing. John Woodard, Ph.D., associate professor of psychology in the College of Liberal Arts and Sciences and Institute of Gerontology at Wayne State University, is lead author of "Predicting Cognitive Decline in Healthy Older Adults Using fMRI" published in the Journal of Alzheimer's Disease (vol. 21, no. 3). "No one had studied ...

CAMBRIDGE, Mass. -- MIT scientists have discovered that cells lining the blood vessels secrete molecules that suppress tumor growth and keep cancer cells from invading other tissues, a finding that could lead to a new way to treat cancer. Elazer Edelman, professor in the MIT-Harvard Division of Health Sciences and Technology (HST), says that implanting such cells adjacent to a patient's tumor could shrink a tumor or prevent it from growing back or spreading further after surgery or chemotherapy. He has already tested such an implant in mice, and MIT has licensed the technology ...

Baked goods made from hydrolyzed wheat flour are not toxic to celiac disease patients, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute. Celiac disease occurs in the digestive system when people cannot tolerate a protein called gluten, which is found primarily in wheat. "This is the first time that a wheat flour-derived product is shown to not be toxic after being given to celiac patients for 60 days," said Luigi Greco, MD, PhD, of the University of Napes, Italy, ...

Montreal, January 19, 2011 – Toddlers who learn a second language from infancy have an edge over their unilingual peers, according to a new study from Concordia University and York University in Canada and the Université de Provence in France. As reported in the Journal of Experimental Child Psychology, the research team tested the understanding of English and French words among 24-month-olds to see if bilingual toddlers had acquired comparable vocabulary in each language. "By 24 months, we found bilingual children had already acquired a vocabulary in each of their two ...

CHAPEL HILL, N.C. – Scientists around the world have been hot on the trail of a genetic mutation closely associated with some brain cancers and leukemia since the mutation's discovery in 2008. The hunt is now yielding fruit. In the Jan. 18, 2011 issue of Cancer Cell, researchers reveal how the mutation contributes to cancer development and suggest potential ways to counter its effects. About 75 percent of people with low-grade brain tumors and 20 percent of people with acute myeloid leukemia have a mutated version of a gene known as IDH. IDH helps cells metabolize, or ...

PITTSBURGH, Jan. 18 – Family caregivers who had not discussed life support measures with critically ill patients took nearly two weeks longer to decide to forego further medical intervention than those who had prior conversations about the issues, according to researchers from the University of Pittsburgh School of Medicine and the Graduate School of Public Health. They share their findings in a poster presentation at the Society of Critical Care Medicine congress this week in San Diego. Also, a patient's loved ones were more confident about acting as surrogate decision-makers ...

Washington, DC, January 19, 2011— Both boys and girls who are victims of bullying, including bullying through e-mail and the internet, are at elevated risk for depression. However, according to a new study, adolescent girls may engage in substance use as a result of bullying-related depression,. As schools reopen following the holidays, the message to parents of adolescent girls is that bullying can have serious consequences:"If your daughter is a victim of bullying, take it seriously, do all possible to prevent recurrence, and attend to possible depression and substance ...

Serious traffic gridlocks, like the jam on Beijing's national expressway a few months ago which brought vehicles to a halt for days, are a real-world issue needing attention. Unfortunately, such standstills are not uncommon in Beijing, or in other cities around the world. Such incidents motivate the analysis of traffic to minimize similar events and provide insight into road design and construction, such as where to install traffic lights and toll booths, how many lanes to build, and where to construct an overpass or a tunnel. The goals of these analyses are to relieve ...

MANHATTAN, Kan. -- The forecast for predicting the next political hotspots could be much more accurate because of a model developed by two Kansas State University professors and a colleague in New York. The model, named the Predictive Societal Indicators of Radicalism Model of Domestic Political Violence Forecast, is currently five for five in predicting which countries will likely experience an escalation in domestic political violence against their governments within the next five years. "So far it's been pretty accurate," said Sam Bell, assistant professor of political ...

TORONTO, Ont., Jan. 19, 2011–Health care systems around the world are failing to use evidence obtained through research when making decisions, causing inefficiencies and reduced quantity and quality of life, according to a leading expert in the field of "knowledge translation." "Failures to use research evidence to inform decision-making are apparent across all key decision-maker groups," said Dr. Sharon Straus, a geriatrician and director of knowledge translation at St. Michael's Hospital. Dr. Straus was the guest editor of the January issue of the Journal of Clinical ...

CHAMPAIGN, Ill. —Two aquatic biologists have proven that you don't have to travel to exotic locales to search for unusual new species. They discovered a distinctive species of crayfish in Tennessee and Alabama that is at least twice the size of its competitors. Its closest genetic relative, once thought to be the only species in its genus and discovered in 1884 about 130 miles away in Kentucky, can grow almost as big as a lobster. The researchers found their first specimen under one of the biggest rocks in the deepest part of a creek that has been a (literal) stomping ...