Vancouver, BC - Scientists supported by Genome BC have set a new standard for studying outbreaks of infectious disease by combining advanced genomics with a detailed map of the social relationships between cases to investigate a recent outbreak of tuberculosis in a BC community. The study tracked 41 individuals who developed tuberculosis: patient interviews revealed a tightly-knit community where most patients knew one another, while DNA fingerprinting of the bacterial samples from each individual showed them to be identical to each other. These two factors together ...

Imagine your city isn't as safe as it used to be. Robberies are on the rise, home invasions are increasing and murder rates have nearly doubled in the past three years. What should city officials do about it? Hire more cops to round up the thugs and lock them away in a growing network of prisons? Or design programs that promise more peace by addressing issues like a faltering economy and underperforming schools? Your answer – and the reasoning behind it – can hinge on the metaphor being used to describe the problem, according to new research by Stanford psychologists. ...

ANN ARBOR, Mich. – Doctors are increasingly using a convenient blood glucose test for diagnosing diabetes and pre-diabetes, but a study by the University of Michigan's C.S. Mott Children's Hospital shows it's not the best way to diagnose diabetes in children. The hemoglobin A1c test has become the preferred way to diagnose diabetes among the millions of Americans who have diabetes but show no symptoms. The simple test measures longer-term blood sugar levels -- without requiring patients to fast overnight. But U-M researchers say more study is needed before doctors ...

Americans and Canadians are getting vastly different search results when they look up prescription drug information online, says a study by researchers at the University of British Columbia. Residents of the United States searching on Google for both brand and generic drug names get directed to the government-run National Library of Medicine. However, Canadians performing the same searches end up getting Wikipedia for generic drug searches, and drug company sites for brand searches, according to the study, published online yesterday by the Annals of Pharmacotherapy. "The ...

CHAMPAIGN, Ill. — Researchers have developed a simple method of making short protein chains with spiral structures that can also dissolve in water, two desirable traits not often found together. Such structures could have applications as building blocks for self-assembling nanostructures and as agents for drug and gene delivery. Led by Jianjun Cheng, a professor of materials science and engineering at the University of Illinois, the research team will publish its findings in the Feb. 22 edition of the journal Nature Communications. Materials scientists have been interested ...

The preliminary results of the Semporna Marine Ecological Expedition (December 2010) indicate that Semporna may have the world's highest marine biodiversity. The expedition yielded a record number of 43 species of mushroom corals. Furthermore, some new species were discovered, among which at least two shrimps and possibly a number of gall crabs. The health of the reefs was judged to be relatively poor: 36% of the transects had fair, another 36% had poor live coral cover. Eighteen scientists from Malaysia, the Netherlands and the USA spent three weeks examining the reefs ...

Complementary and alternative medicine (CAM) is increasingly popular in maternity care, but healthcare professionals need formal evidence-based education and guidance about its use, according to a review in the March issue of the Journal of Advanced Nursing. There is also need for greater respect and cooperation between conventional and alternative practitioners and improved communication with patients about the growing use of CAM. University-based members of the Network of Researchers in the Public Health of Complementary and Alternative Medicine (NORPHCAM) reviewed ...

Immunology: Three percent of the world's population is currently infected by hepatitis C. The virus hides in the liver and can cause cirrhosis and liver cancer, and it's the most frequent cause of liver transplants in Denmark. Since the virus mutates strongly, we have no traditional vaccine, but researchers at the University of Copenhagen are now the first to succeed in developing a vaccine, which provides future hope for medical protection from this type of hepatitis. "The hepatitis C virus (HCV) has the same infection pathways as HIV," says Jan Pravsgaard Christensen, ...

Pukas Surf (the leading manufacturer and distributor of high-performance surfboards in Europe) and Tecnalia Research & Innovation have presented their research work into the mechanical behaviour of surfboards. Surfing is still a sport governed by feelings. Most innovations in board design and manufacture, as well as analysis of surfing technique, have been the result of "trial and error" procedures and the experiences of shapers, trainers and surfers. The driving forces behind this joint project aim to "turn feelings into facts and figures" and provide as yet unquantified ...

CLEVELAND – February 21, 2011 – New research shows that medications which have raised safety concerns over heart attack and stroke risks may not have gotten approval from the Food and Drug Administration (FDA) if the cardiovascular effects of fluid retention had been better understood. Fluid retention may explain the increased risk of heart attacks and strokes of medications such as Vioxx®, Bextra®, and Avandia®. The research published in Clinical Hemorheology and Microcirculation (IOS Press, ISSN 1386-0291), calculates the effects of fluid retention upon the velocity ...

New research determined that an increase in the severity of hallux valgus, or bunion deformity, progressively reduced both general and foot-specific health related quality of life (HRQOL). Bunion deformity was found in 36% of the study population and occurred more frequently in women and older individuals. Pain in other parts of the body beyond the foot was associated with increased bunion severity. Details of this UK population-based study appear in the March issue of Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of ...

"The presence of two resistent forms of protozoons, the oocysts from the Cryptosporidium genus and cysts of the Giardia genus, is one of the greatest public health problems in water supply, because these parasites can easily survive our water treatment systems", José Antonio Castro Hermida, a scientist at the Galician Institute for Food Quality in the Xunta de Galicia (regional government), tells SINC. A team led by this researcher took 232 water samples in 55 Galician towns, and confirmed the presence of these infectious life forms in waste water treatment plants, drinking ...

This release is available in Spanish and French. Drivers aged over 60 have higher crash rates in non problematic operating environments –as in junctions– than drivers of other age groups. Although elderly drivers present deteriorated driving abilities, they have proved to be more cautious, to compensate such deficiencies. This way, older drivers avoid engaging in risky behaviours like speeding, passing dangerously or driving under the effects of alcohol. Such were the conclusions drawn of the study conducted by University of Granada researchers and recently published ...

Almost 600 million years ago, before the rapid evolution of life forms known as the Cambrian explosion, a community of seaweeds and worm-like animals lived in a quiet deep-water niche near what is now Lantian, a small village in south China. Then they simply died, leaving some 3,000 nearly pristine fossils preserved between beds of black shale deposited in oxygen-free and unbreathable waters. Scientists from the Chinese Academy of Sciences, Virginia Tech in the United States and Northwest University in Xi'an, China report the discovery of the fossils in the Feb. 17 ...

Tel Aviv — Civil protests, from peaceful sit-ins at the Pentagon to violent riots in Cairo, nonetheless share some common characteristics. To study how protests evolve in public spaces, Dr. Tali Hatuka, an architect and head of Tel Aviv University's Laboratory of Contemporary Urban Design, has dissected some of the world's most publicized protests — those in Washington, Istanbul, Tel Aviv, Beijing, and Leipzig. History shows that protests and civil disobedience are inevitable and necessary expressions of dissent in any democratic nation — and under many authoritarian ...

Researchers at IRB Barcelona have completed the 3D structural sequence adopted by several essential proteins in the exchange of substances between the extra and intracellular milieu. This finding provides a global perspective of the structural changes that occur in these relevant proteins during basic cell processes, such as protein synthesis, the regulation of metabolism and cell volume, and nerve transmission. The exchange of substances between the intra and extra cellular environment is performed by transporter proteins located in cell membranes. These proteins act ...

Troy, N.Y. – In the restaurant of the future, you will always enjoy the perfect meal with that full-bodied 2006 cabernet sauvignon, you will always know your dinner companions' favorite merlot, and you will be able to check if the sommelier's cellar contains your favorite pinot grigio before you even check your coat. These feats of classic cuisine will come to the modern dinner through the power of Semantic Web technology. Web scientist and Rensselaer Polytechnic Institute Tetherless World Research Constellation Professor Deborah McGuinness has been developing a family ...

This release is available in German. They have been used as standard in multimedia electronics for a long time, and now they are making rapid inroads in high performance applications: CMOS image sensors are no longer only used in cell phones and digital cameras. The automotive industry, for instance, has discovered the potential of optical semiconductor chips and is increasingly using them in driver assistance systems – from parking aids and road lane detection to blind-spot warning devices. In special applications, however, the sensors that convert light into electrical ...

Philadelphia, PA, 23 February 2011 - Understanding the genetics of bipolar disorder could lead to new treatments, but identifying specific genetic variations associated with this disorder has been challenging. A new study in Biological Psychiatry implicates a brain protein called Piccolo in the risk for inheriting bipolar disorder. In the orchestra of neuronal proteins, Piccolo is a member of a protein family that includes another protein called Bassoon. Piccolo is located at the endings of nerve cells, where it contributes to the ability of nerve cells to release their ...

Millions of people dealing with health issues have found comfort sharing their stories online with others who experience similar ailments, but research on their clinical effectiveness is limited, and findings are mixed. Among people with mental illnesses, the results are sparser, even though research has shown that this group prefers online peer support groups over face-to-face support groups. To that end, Mark Salzer, chair of the Rehabilitation Department at Temple University, studied the effectiveness of online peer support for people with a mental illness in what ...

Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible for this genetic readout, but is prone to transcriptional arrest. The biochemist Professor Patrick Cramer, Director of LMU's Genzentrum, and his research associate Dr. Alan Cheung have now shown for the first time – and captured on film -- what happens when Pol II arrests at a "roadblock". They were even able to observe how transcript is reactivated. ...

This release is available in German. Most large wind turbines currently operate at variable speeds. When the wind is strong, the rotor turns fast; when it slows down, the rotor speed drops. Typically rotors complete 12 to 16 revolutions per minute. The generator is connected to the rotor via a gearbox. Here too, the speed of rotation varies with the speed of the wind. Yet, a wind turbine may only feed alternating current with exactly the frequency of the electric grid. That is why the alternating current from generators is today transformed into direct current by way ...

With most people unable to get enough vitamin D from sunlight or foods, scientists are suggesting that a new vitamin D-fortified food — bread made with high-vitamin D yeast — could fill that gap. Their study, confirming that the approach works in laboratory tests, appears in ACS' Journal of Agricultural and Food Chemistry. Connie Weaver and colleagues cite studies suggesting that up to 7 in 10 people in the United States may not get enough vitamin D, which enables the body to absorb calcium. Far from just contributing to healthy bones, however, vitamin D seems to have ...

University of British Columbia geophysicists are offering a new explanation for seismic tremors accompanying volcanic eruptions that could advance forecasting of explosive eruptions such as recent events at Mount Pinatubo in the Philippines, Chaiten Volcano in Chile, and Mount St. Helens in Washington State. All explosive volcanic eruptions are preceded and accompanied by tremors that last from hours to weeks, and a remarkably consistent range of tremor frequencies has been observed by scientists before and during volcanic eruptions around the world. However, the underlying ...

Scientists who examined more than 10,000 chemical compounds during the last year in search of potential new drugs for a group of untreatable brain diseases, are reporting that one substance shows unusual promise. The early positive signs for so-called prion diseases come from research in laboratory mice and cell cultures, they say in a report in ACS' Journal of Medicinal Chemistry. Adam Renslo and colleagues, who include Nobel Laureate Stanley B. Prusiner, explain that prion diseases include conditions like mad cow disease in animals and Creutzfeldt-Jakob Disease in humans, ...