ORLANDO - A two-drug combination is safe and active in newly diagnosed acute myeloid leukemia and myelodysplastic syndrome patients who are usually excluded from clinical trials because they have other illnesses or poor performance status - a measure of disease progression - researchers reported this week at the 52nd American Society of Hematology Annual Meeting. "Our findings suggest current eligibility standards that prevent participation by these patients in phase I and phase II clinical trials might be inadequate," said Guillermo Garcia-Manero, M.D., professor in ...

Scientists have discovered how a network of repair proteins enables bacteria to prioritise the repair of the most heavily used regions of the DNA molecules that carry the instructions necessary for living cells to function. The research, carried out by academics at the University of Bristol and published in Molecular Cell (Dec. 2010), reveals that there are greater similarities between the DNA repair systems of bacteria and humans than had been suspected. When the chemical "letters" in a cell's DNA book of instructions are damaged the instructions become difficult ...

San Antonio - Metastatic breast cancer patients whose blood contains circulating tumor cells (CTCs) before or after treatment with high-dose chemotherapy and blood stem cell transplant have shorter survival periods, according to a new study by researchers at The University of Texas MD Anderson Cancer Center in Houston. The findings were presented today in a poster session at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium. In addition, patients with higher percentages of epithelial cells, or the presence of a specific cellular transition, had higher chances ...

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. The information is embargoed for the time of presentation at the symposium. HOXB7 GENE PROMOTES TAMOXIFEN RESISTANCE (Presentation # PD05-10) Many postmenopausal women with early-stage breast cancers who initially respond well to tamoxifen become ...

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. The information is embargoed for the time of presentation at the symposium. TRIO OF DRUGS MAY COMBAT "TRIPLE NEGATIVE" BREAST CANCER (Presentation # PD01-05) Working with cell cultures and mouse models, researchers at the Johns Hopkins Kimmel ...

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. The information is embargoed for the time of presentation at the symposium. SIMPLE FINGERTIP TEST MAY IDENTIFY BREAST CANCER PATIENTS AT RISK FOR CARPAL TUNNEL SYNDROME (Presentation # P2-14-09) As many as half of postmenopausal women taking aromatase ...

PITTSBURGH— Nonchemical treatment systems are touted as environmentally conscious stand-ins for such chemicals as chlorine when it comes to cleaning the water-based air-conditioning systems found in many large buildings. But a recent study by University of Pittsburgh researchers suggests that this diverse class of water-treatment devices may be ineffective and can allow dangerous bacteria to flourish in the cooling systems of hospitals, commercial offices, and other water-cooled buildings almost as much as they do in untreated water. The two-year study by a team in Pitt's ...

"Directed Self-Assembly of Vertical Nanotubes for Biosensors, Logic, and Nano-Biofuel Cells," will be the focus of NJIT's exhibit today at the National Nanotechnology Innovation Summit 10 http://www.nsti.org/events/NNI/, at the Gaylord Center in Washington, DC. The event celebrates the 10th anniversary of the national nanotechnology initiative. NJIT was the only university in New Jersey selected for this exposition featuring practical applications of nanoscience resulting from the last decade of federal funding under the National Nanotechnology Initiative (NNI). ...

DALLAS – Dec. 10, 2010 – It's a medical Catch-22: carotid artery surgery can itself cause stroke, but so can asymptomatic carotid disease if left untreated. UT Southwestern Medical Center researchers have now developed a clinical risk prediction rule using factors such as sex, race and health history to assess the danger the surgery poses, while a modified version will help patients make a more fully informed choice about whether to have the procedure. "It may take a thief to catch a thief, but physicians don't want to cause stroke while trying to prevent stroke, so ...

GALVESTON, Texas — "You'll be back on your feet in no time" is a phrase familiar to anyone who's ever had to spend time in a hospital. Now, a new study has shown that hospitalized elderly patients who literally "get back on their feet" by taking even short walks around a hospital unit tend to leave the hospital sooner than their more sedentary peers. Conducted at the University of Texas Medical Branch at Galveston and described in a paper appearing in the current issue of Archives of Internal Medicine, the study draws on data collected from 162 hospitalized patients over ...

It is estimated that 38 million people worldwide are currently infected with HIV and that 4.1 million more are added each year. For scientists to design treatment therapies that are effective over the long-term it is essential to learn more about how the virus mutates and develops resistance to medications. New, groundbreaking research by University of Victoria biomedical engineer Stephanie Willerth has significantly advanced the understanding of HIV and how to treat it. "The virus mutates at a very high rate which is very problematic for HIV patients because the virus ...

(Washington, DC) – A recent study of the use of metaphors in spoken language and various sign languages shows that certain types of metaphors are difficult to convey in sign language. The study, "Iconicity and metaphor: Constraints on metaphorical extension of iconic forms," to be published in the December 2010 issue of the scholarly journal Language, is authored by Irit Meir of the University of Haifa. A preprint version is available on line at: http://lsadc.org/info/documents/2010/press-releases/meir.pdf. Dr. Meir's research sheds new light on the interrelations between ...

The December issue of The Quarterly Review of Biology is now available. The issue features articles on the nature of individual organisms, evolution observed in the lab, play behavior across animal species, and a criticism of intelligent design creationism. Abstracts are available at http://www.journals.uchicago.edu/toc/qrb/current. What is an Individual? For organisms like fish, mice, and people, it's not hard to distinguish between individuals. However, for colonial creatures like corals and anemones, and for organisms like slime molds and bacteria, the line separating ...

SAN FRANCISCO – Scientists from the Department of Energy's Pacific Northwest National Laboratory will present their research at the 2010 American Geophysical Union Fall Meeting, which runs Monday, Dec. 13 through Friday, Dec. 17 at the Moscone Convention Center in San Francisco. SPLAT unearths complex view of airborne particles Measuring individual particles instead of the average reveals a complex landscape Climate researchers trying to characterize aerosol particles – tiny bits of organic molecules, sulfate, dust, soot and more – are limited to measuring averages, ...

Alfred Lee and Don Campbell, authors of the internationally acclaimed book, Perfect Breathing: Transform Your Life One Breath at a Time (Sterling Publishing/New York City), today announced that the makers of BreathSlim , a revolutionary new breathing device that trains users to breathe correctly to fully utilize the power of oxygen, will begin excerpting relevant sections of Perfect Breathing to help users better understand the tremendous impact mindful breathing has on health, well-being and performance. "We are excited about the potential of teaming up to share these ...

Staff Virtual, a leading provider of Virtual Assistants (VAs), provisioning turnkey offshore team development, is pleased to announce new improvements to the company's phone system, and high-speed Internet connections located in our Manila, Philippines offices. Staff Virtual's new phone system, powered by Enzu, is a flexible, cloud-based, multi-extension business phone system with advanced voice and fax functionality, always-on digital-line service, unlimited calling and full-featured phones that arrive pre-configured and ready for use. Staff Virtual chose Enzu, an ...

TonerGreen, the online printer supplies store that produces eco-friendly, U.S.-made and non-patent infringing ink and laser toner cartridges, has just been given an excellent rating by Better Business Bureau, also known as BBB. Better Business Bureau or BBB is a well-known organization that monitors and keeps records of every business that it grants accreditation. A business with a good rating or grade from BBB means that it has great products and customer service, assuring buyers that they are getting more than their money's worth. Furthermore, BBB makes sure that it ...

Emeraldfish.com, the new boutique shopping experience for women and men desiring beautiful, functional and contemporary objects from Italy, France, Germany, Pakistan, Korea and many other countries for modern living, is officially launched today. With today's announcement, EmeraldFish.com online shoppers now have access to a luxurious travel trunk in the form of a distinctive site comprising elements of design, style, and cultural appreciation. Emeraldfish.com merchandise is priced between $25 to $2500, and scaled to every budget level giving shoppers access to beautiful ...

It is no secret that honey helps to soothe the throat and ease the effects of certain illnesses during the cold and flu season. However, one type of honey is being used more successfully than ordinary honey. It has been discovered that Manuka Honey from New Zealand contains healing properties not found in other types of honey, making it extremely effective in treating a wide spectrum of health conditions. Manuka Honey's famed antibacterial properties are now being used in hospitals to ward off antibiotic-resistant strains of bacteria that cause potentially life threatening ...

Tonerboss, the leading HP laser toner cartridge expert, is always providing high quality premium compatible laser toner cartridges and ink cartridges at an affordable price. Exciting promos and discounts are being offered to make sure that Tonerboss shoppers would receive a hundred percent customer satisfaction. For this Christmas Season, Tonerboss.com is giving away free shipping for all orders of premium compatible laser toners and ink cartridges that would reach the amount of $49 and above. This is one of the greasest offers an e-commerce printer supply store like ...

New England Burials At Sea (NEBAS) Founder, Captain Brad White recently chose the Chelsea Clock Company of Boston, MA to be the exclusive supplier of renowned ships clocks to families who select sea burial services. White said, "Chelsea Clocks are the finest clocks and have been made in America for the last 114 years. Chelsea's are known as timekeepers of the sea for the US military and have graced ocean yachts and also stood watch at meetings between heads of state. These clocks are treasured by passionate collectors and are cherished from one generation to the next. From ...

Due to its overwhelming success more than 20 local and nationally recognized dance crews perform live for the second MOTOR CITY MOVEMENT in Pontiac at the Crofoot Ballroom in Pontiac on December 30 at 7:30 p.m. With new acts, featured favorites and the hottest dancers and choreographers in the nation gathered in one place, MOTOR CITY MOVEMENT is set to top its first show this December. Hit shows including America's Best Dance Crew, Dancing With the Stars, and So You Think You Can Dance have all helped to make dance a mainstream art form. Launching in Detroit, MOTOR CITY ...

Rinkya's Yousei (elves) who dwell deep within the Rinkya warehouse packing and shipping Japanese goods to the rest of the world have gotten used to this annual report, once again greeting us with milk and cookies laced with Saki as they give us a quick snapshot of the holiday shopping picture. The oldest Yousei said "Can't spend a lot of time this year yakking, both the new French site and Rinkya Stores have us exhausted up to our eyeballs. "Toys and games are at the top," said the Yousei heading up the Gamer Department. "The Super Mario 25th Anniversary for Nintendo, ...

American Writers & Artists Inc. (AWAI), http://www.awaionline.com, today announced its newest program: The Business Side of B2B Copywriting: How to Get Clients, Grow Your Business, and Boost Your Income and invited participants to work together to stay motivated and launch their own B2B copywriting businesses in time for the New Year. "With B2B copywriting you can be in control of your own fate" said Pete Savage, thriving B2B copywriter, and co-author of The Business Side of B2B Copywriting, in a recent teleconference broadcast to AWAI members. Ed Gandia, also a successful ...

Although each type of female entrepreneur will find a masterminding group and situation that meets her unique needs and desires, every entrepreneur should carefully consider several topics when creating or joining a mastermind group, to ensure she receives the maximum benefit. Best of the Janes: Getting the Most Out of Masterminding is the latest article by entrepreneurial expert Michele DeKinder-Smith. The article reveals three considerations every entrepreneur must consider when creating a mastermind group - so they can reap the maximum rewards of this powerful concept. ...