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DHS report on risks of proposed Kansas biocontainment lab is incomplete

2010-11-16
WASHINGTON — A new National Research Council report requested by Congress finds "several major shortcomings" in a U.S. Department of Homeland Security assessment of risks associated with operating the proposed National Bio- and Agro-Defense Facility (NBAF) in Manhattan, Kan. The laboratory would study dangerous foreign animal diseases -- including the highly contagious foot-and-mouth disease (FMD), which affects cattle, pigs, deer, and other cloven-hoofed animals -- and diseases deadly to humans that can be transmitted between animals and people. Based on the DHS risk ...

Time to prepare for climate change

Time to prepare for climate change
2010-11-16
WASHINGTON – Though the massive glaciers of the greater Himalayan region are retreating slowly, development agencies can take steps now to help the region's communities prepare for the many ways glacier melt is expected to impact their lives, according to a new report. Programs that integrate health, education, the environment and social organizations are needed to adequately address these impacts, the report states. "The extremely high altitudes and sheer mass of High Asian glaciers mean they couldn't possibly melt in the next few decades," said Elizabeth Malone, a Battelle ...

T. rex's big tail was its key to speed and hunting prowess

2010-11-16
Tyrannosaurus rex was far from a plodding Cretaceous era scavenger whose long tail only served to counterbalance the up-front weight of its freakishly big head. T. rex's athleticism (and its rear end) has been given a makeover by University of Alberta graduate student Scott Persons. His extensive research shows that powerful tail muscles made the giant carnivore one of the fastest moving hunters of its time. As Persons says, "contrary to earlier theories, T. rex had more than just junk in its trunk." The U of A paleontology student began his research by comparing ...

Microsensors offer first look at whether cell mass affects growth rate

2010-11-16
CHAMPAIGN, Ill. — University of Illinois researchers are using a new kind of microsensor to answer one of the weightiest questions in biology – the relationship between cell mass and growth rate. The team, led by electrical and computer engineering and bioengineering professor Rashid Bashir, published its results in the online early edition of the Proceedings of the National Academy of Sciences. "It's merging micro-scale engineering and cell biology," said Bashir, who also directs the Micro and Nanotechnology Engineering Laboratory at Illinois. "We can help advance ...

Biochemistry of how plants resist insect attack determined

2010-11-16
Many plants, including crops, release volatiles in response to insect attack. The chemical compounds can be a defense or can be an aromatic call for help to attract enemies of the attacking insect. Researchers from Virginia Tech, Michigan State University, and Georg-August-University Göttingen have discovered how plants produce the defensive compounds. The research is reported this week in the online early edition of the Proceedings of the National Academy of Sciences. The article, "Herbivore-induced and floral homoterpene volatiles are biosynthesized by a single P450 ...

New research changes understanding of C4 plant evolution

2010-11-16
Frostburg, Md. (November 15, 2010) – A new analysis of fossilized grass-pollen grains deposited on ancient European lake and sea bottoms 16-35 million years ago reveals that C4 grasses evolved earlier than previously thought. This new evidence casts doubt on the widely-held belief that the rise of this incredibly productive group of plants was driven by a large drop in atmospheric carbon dioxide concentrations during the Oligocene epoch. The research team, led by University of Maryland Center for Environmental Science Appalachian Laboratory researcher Dr. David Nelson ...

Adding pharmacists to docs' offices helps patient outcomes, study shows

2010-11-16
Adding pharmacists to the primary care team right in doctors' offices may help patients with chronic diseases such as diabetes better manage associated risks, a new University of Alberta study had found. The blood pressure of patients with Type 2 diabetes dropped significantly when pharmacists were included in the on-site clinical examination and consulting process, the U of A study showed. Among 153 patients whose hypertension was inadequately controlled at the beginning of the study, the 82 who had advice from a pharmacist were more likely to reach blood pressure treatment ...

Guiltless gluttony: Misleading size labels lead to overeating

2010-11-16
People are easily fooled when it comes to food labels, and will eat more of something if they believe it's a "small" portion, according to a new study in the Journal of Consumer Research. Authors Nilufer Z. Ayinoglu (Koç University, Istanbul) and Aradhna Krishna (University of Michigan) found that inconsistent portion sizes contribute to people's uncertainty about the appropriate amount to eat. "In this context of large portion sizes and consumer uncertainty about appropriate food intake, we show that size labels chosen by food and drink vendors (such as 'small-medium-large') ...

Do consumers prefer 1 percent interest over 0 percent interest or is zero simply confusing?

2010-11-16
Why would someone choose a credit card with a one percent interest rate over another with a zero percent rate? A new study in the Journal of Consumer Research finds that consumers are often flummoxed when it comes to zero. "A reasonable assumption is that a product will be more attractive when it offers more of a good thing, such as free pictures (with a digital camera purchase), or less of a bad thing, like interest rates on a credit card," writes author Mauricio Palmeira (Monash University, Australia). But Palmeira's research found that consumer comparison methods tend ...

Natural compound shows promise against Huntington's disease

Natural compound shows promise against Huntingtons disease
2010-11-16
LA JOLLA, CA-Fisetin, a naturally occurring compound found in strawberries and other fruits and vegetables, slows the onset of motor problems and delays death in three models of Huntington's disease, according to researchers at the Salk Institute for Biological Studies. The study, published in the online edition of Human Molecular Genetics, sets the stage for further investigations into fisetin's neuroprotective properties in Huntington's and other neurodegenerative conditions. Huntington's disease (HD) is an inherited disorder that destroys neurons in certain parts of ...

Tiny RNA molecules control labor, may be key to blocking premature birth

2010-11-16
DALLAS – Nov. 15, 2010 – Tiny molecules called microRNAs act together with hormones to control the onset of labor, raising the prospect that RNA-based drugs might be able to prevent premature labor, researchers at UT Southwestern Medical Center have discovered in a preclinical study. "With these findings, we understand better the system that controls labor, so with future research we might have the potential to manipulate it and prevent preterm birth," said Dr. Carole Mendelson, professor of biochemistry and obstetrics and gynecology at UT Southwestern and senior author ...

Shopping religiously

2010-11-16
Marketers hope to connect between the consumer and the products they represent by creating a strong brand identity. Now a Tel Aviv University researcher is giving marketers a heavenly new angle to consider ― religious faith ― on which to build their advertising strategies. Prof. Ron Shachar of Tel Aviv University's Leon Recanati Graduate School of Business Administration says that a consumer's religiosity has a large impact on his likelihood for choosing particular brands. Comsumers who are deeply religious are less likely to display an explicit preference ...

Does the wisdom of crowds prevail when betting on football?

2010-11-16
Point spreads—the number of points by which a strong team can be expected to defeat a weaker team—are supposed to reflect the "wisdom of crowds." But a new study in the Journal of Consumer Research found that crowds don't have a clue. "Point spread betting markets seem to offer an important example of crowd wisdom, because point spreads are very accurate and are widely believed to reflect the 'crowd's' prediction of upcoming sporting events," write authors Joseph P. Simmons (Yale University), Leif D. Nelson (University of California at Berkeley), Jeff Galak (Carnegie ...

The bitter breakup: What happens when consumers dump their brands?

2010-11-16
It's just like a bad breakup: People get emotional when they end a relationship with a brand. A new study in the Journal of Consumer Research examines what happens when people turn their backs on the brands they once loved. "Customers who were once enthusiastic about a brand may represent a headache for the associated firm beyond the lost revenue of foregone sales because they sometimes become committed to harming the firm," write authors Allison R. Johnson (University of Western Ontario), Maggie Matear (Queens University, Kingston, Ontario), and Matthew Thomson (University ...

When pride in achievement leads to a large order of fries

2010-11-16
You aced that test; now it's time for a treat. Sometimes pride in an achievement can lead people to indulge in unhealthy choices, according to a new study in the Journal of Consumer Research. "Across four studies in the food consumptions and spending domains, we show that pride is associated with two opposing forces; it promotes a sense of achievement, which increases indulgence, and it promotes self-awareness, which facilitates self control," write authors Keith Wilcox (Babson College), Thomas Kramer (University of South Carolina), and Sankar Sen (Baruch College). The ...

Understanding consumer behavior: Make them think it was their idea or decision?

2010-11-16
Consumers value goals they've chosen on their own more than those that are imposed on them, according to a new study in the Journal of Consumer Research. "When people believe they have autonomously chosen to pursue a goal themselves, they feel the goal is increasingly valuable as they put in more effort, because they experience their own effort as signaling how much they care about it," write authors Ying Zhang (University of Texas at Austin), Jing Xu, Zixi Jiang (both Peking University), and Szu-chi Huang (University of Texas at Austin). It seems that when people ...

Is heart disease genetic destiny or lifestyle?

2010-11-16
CHICAGO --- Is cardiovascular health in middle age and beyond a gift from your genes or is it earned by a healthy lifestyle and within your control? Two large studies from Northwestern Medicine confirm a healthy lifestyle has the biggest impact on cardiovascular health. One study shows the majority of people who adopted healthy lifestyle behaviors in young adulthood maintained a low cardiovascular risk profile in middle age. The five most important healthy behaviors are not smoking, low or no alcohol intake, weight control, physical activity and a healthy diet. The other ...

Internal body clock controls fat metabolism, UCI study shows

2010-11-16
Irvine, Calif., Nov. 15, 2010 — UC Irvine researchers have discovered that circadian rhythms – the internal body clock – regulate fat metabolism. This helps explain why people burn fat more efficiently at certain times of day and could lead to new pharmaceuticals for obesity, diabetes and energy-related illnesses. The study was headed by Paolo Sassone-Corsi, Donald Bren Professor and chair of pharmacology. A leading expert on circadian rhythms, he discovered many of the key molecular switches governing these biological processes. He and his colleagues found that one of ...

Brain scans detect autism's signature

2010-11-16
An autism study by Yale School of Medicine researchers using functional magnetic resonance imaging (fMRI) has identified a pattern of brain activity that may characterize the genetic vulnerability to developing autism spectrum disorder (ASD). Published today in the early edition of Proceedings of the National Academy of Sciences, the study could eventually lead to earlier and more accurate autism diagnosis. ASD is defined by impaired social interaction and communication, and can disrupt the brain's ability to interpret the movements of other people, known as "biological ...

Iron in coronary artery plaque is a marker of heart attack risk, say Mayo Clinic researchers

2010-11-16
CHICAGO - Plaque in a heart artery looks threatening, but cardiologists know that many of these buildups will not erupt, dislodge and block a vessel, causing a heart attack that can be fatal. Some will, however, and the challenge is to figure out atherosclerotic plaque that is dangerous and treat or remove it. Now, researchers at Mayo Clinic have shown that iron, derived from blood, is much more prevalent in the kind of plaque that is unstable and is thus more likely to promote a myocardial infarction (MI) - heart attack - and possibly sudden death. The team of researchers ...

Reducing salt in teen diet could have big impact on future health

2010-11-16
Cutting back on salt in teenagers' diets by as little as one-half teaspoon, or three grams, a day, could reduce the number of young adults with high blood pressure by 44 to 63 percent, according to new research presented Sunday, Nov. 14 at the American Heart Association's Scientific Sessions 2010 meeting in Chicago. The findings indicate that the food industry and those who regulate it could substantially improve the nation's health through even small reductions in the amount of salt in processed foods, which account for the majority of salt consumed in this country. "The ...

Erythropoietin counteracts breast cancer treatment with herceptin

Erythropoietin counteracts breast cancer treatment with herceptin
2010-11-16
HOUSTON - Red-blood-cell-boosting drugs used to treat anemia may undermine breast cancer treatment with Herceptin, a targeted therapy that blocks the cancer-promoting HER2 protein, researchers from The University of Texas MD Anderson Cancer Center report in the Nov. 16 edition of Cancer Cell. "Our research indicates when the two drugs were used at the same time, Herceptin was less effective," said study senior author Zhen Fan, M.D., associate professor in MD Anderson's Department of Experimental Therapeutics. Natural erythropoietin (EPO) controls the body's red blood ...

Stem cell patch may result in improved function following heart attack

2010-11-16
CINCINNATI—University of Cincinnati (UC) researchers have found that applying a stem cell-infused patch together with overexpression of a specific cell instruction molecule promoted cell migration to damaged cardiac tissue following heart attack and resulted in improved function in animal models. The researchers also found that function improved more so than when stem cells were directly injected in heart tissue—a therapy that is being studied elsewhere. These findings are being presented for the first time at the American Heart Association's Scientific Meeting in Chicago ...

Shortest-pulse X-ray beams could illuminate atomic, molecular interactions

2010-11-16
ANN ARBOR, Mich.---Ultra-short X-ray beams produced at the University of Michigan could one day serve as more sensitive medical diagnostic tools, and they could work like strobe lights to allow researchers to observe chemical reactions that happen in quadrillionths of a second. The researchers used the HERCULES high-intensity, table-top laser to create X-ray beams that rival those made in expensive and massive synchrotron particle accelerators. The National Synchrotron Light Source II, for example, under construction at Brookhaven National Laboratory, is slated to be ...

Novel ocean-crust mechanism could affect world's carbon budget

2010-11-16
The Earth is constantly manufacturing new crust, spewing molten magma up along undersea ridges at the boundaries of tectonic plates. The process is critical to the planet's metabolism, including the cycle of underwater life and the delicate balance of carbon in the ocean and atmosphere. Now, scientists at the Woods Hole Oceanographic Institution (WHOI) have observed ocean crust forming in an entirely unexpected way—one that may influence those cycles of life and carbon and, in turn, affect the much-discussed future of the world's climate. Working at the Guaymas basin ...
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