This Friday sees fashion retailer New Look open their biggest ever store in Dublin's Jervis centre. This follows the huge success of the opening of their flagship store on bustling Oxford Circus, London. The store opening party is on 4th November, and invites a mix of press, bloggers, celebrities and competition winners to come and enjoy the show and the store. With music, bubbly, food and a fashion show planned, excitement is building towards the official store opening on 5th November. The store opening follows countdowns in the local press over the last couple of ...

Acapulco in Mexico is one of the most visited tourist destination and it attracts thousands of visitors each year. Acapulco is known for its lovely beaches, its pleasant climate and its many entertainment activities. The night life here is legendary and it is known to be a lively, vibrant place at night. There are many sophisticated and interesting restaurants, night clubs and bars in Acapulco and its very vibe is quite magical and enjoyable. The Acapulco Bay is a great view with its crystal clear water and it is often the most preferred choice for newly weds to enjoy their ...

Smart Software, Inc., provider of industry-leading demand forecasting, planning, and inventory optimization solutions, today announced that Quala S.A., with operations in six Latin American countries and one of the largest consumer goods manufacturing companies in Colombia, has gone live with Smart Software's flagship product, SmartForecasts. Quala replaced its legacy forecasting software with SmartForecasts and will utilize the new forecasting system as the foundation of its sales and operations planning process for its Colombian operations. Forecasting results are integrated ...

Corcentric, a leading provider of accounts payable automation solutions, today announced the appointment of James Wright as National Account Manager. He brings over 15 years of consultative sales experience to Fortune 1000 companies, focusing in the area of Accounts Payable Automation. Mr. Wright is responsible for building the client base for Corcentric's accounts payable solution, COR360, which enables companies to manage 100% of their paper and electronic invoice submissions, invoice approvals and matching, supplier customer service, purchase order requisitioning, ...

Didriks - www.didriks.com - announces the introduction of Brahms Mount artisanal blankets and textiles to its home furnishing collection. Brahms Mount, a signature American brand preserving a tradition of fine textile weaving in Hallowell, Maine, complements Didriks existing collection of high quality textiles which include Libeco Home, Jokipiin Pellava, and Chilewich. Brahms Mount blankets, throws and towels are woven on antique shuttle looms in an 1866 historic mill. Brahms Mount maintains an uncompromising attention to quality and to natural fibers and dyes to create ...

Catapults are often associated with a medieval means of destruction, but for some plants, they are an effective way to launch new life. Dispersing seeds greater distances by catapulting can provide selective advantages, including the establishment of populations in new environments and escape from certain threats. In new work published in the recent October issue of American Journal of Botany (http://www.amjbot.org/cgi/reprint/97/10/1595), Dr. Ellerby, students, and postdoctoral researcher Shannon Gerry at Wellesley College measured the mechanics involved in catapulting ...

SAN DIEGO, CA (November 3, 2010)—Removal of the prostate gland often eradicates early-stage cancer. But patients whose cancer has spread may need to follow up with what is known as salvage radiation therapy. Researchers at Fox Chase have now determined a better way to monitor outcomes after this procedure. A team led by Mark Buyyounouski, M.D., M.S., radiation oncologist at Fox Chase who will present the results at the annual meeting of the American Society for Radiation Oncology, found that levels of a prostate-specific protein up to 18 months after salvage radiation ...

A major CSIRO breakthrough in wireless technology designed to bring broadband to people living beyond the optical fibre network, has been unveiled in Sydney. The first half of CSIRO's Ngara technolgy will enable multiple users to upload information at the same time, without reducing their individual systems' data transfer rate of 12 Mbps. "Someone who doesn't live near the fibre network could get to it using our new wireless system," CSIRO ICT Centre Director Dr Ian Oppermann said. "They'd be able to upload a clip to YouTube in real-time and their data rate wouldn't ...

BETHESDA, MD – October 15, 2010 – Thousands of the world's top scientists and clinicians in the human genetics field will convene to present their latest research findings at the American Society of Human Genetics (ASHG) 60th Annual Meeting, on November 2-6, 2010, in Washington, D.C. A number of the scientific papers presented at the ASHG 2010 meeting will provide information about important new research findings in statistical genetics and genetic epidemiology. One such research abstract of interest on these topics titled, "Mitochondrial Haplogroup X is Associated with ...

New research is helping to unravel the events that underlie the "spread" of Alzheimer's disease (AD) throughout the brain. The research, published by Cell Press in the November 4th issue of the journal Neuron, follows disease progression from a vulnerable brain region that is affected early in the disease to interconnected brain regions that are affected in later stages. The findings may contribute to design of therapeutic interventions as targeting the brain region where AD originates would be simpler than targeting multiple brain areas. An alteration in brain levels ...

New research provides fascinating insight into mechanisms that underlie recovery after damage to a region of the brain important for memory and attention. The research, published by Cell Press in the November 4th issue of the journal Neuron, highlights the role of undamaged portions of the brain that can "take over" and support the recovery of function. Brain damage can have devastating consequences, depending on the location and severity of the injury. Damage to an area of the brain called the prefrontal cortex often results in deficits in memory and attention. However, ...

HOUSTON ― An antibody loaded with an anti-cancer agent produced complete or partial remissions in 38 percent of patients with relapsed or therapy-resistant Hodgkin lymphoma enrolled in a phase I clinical trial, investigators report in the Nov. 4 issue of the New England Journal of Medicine. "That level of objective responses to a drug is impressive for a Phase I trial," said study lead author Anas Younes, M.D., professor in The University of Texas MD Anderson Cancer Center's Department of Lymphoma/Myeloma. "These encouraging results are being confirmed in a large ...

SAN DIEGO, Nov. 3 – Stereotactic body radiotherapy (SBRT), a radiation therapy procedure pioneered at the University of Pittsburgh Cancer Institute (UPCI) that precisely delivers a large dose of radiation to tumors, may effectively control and treat head and neck cancers when combined with the chemotherapy Cetuximab, according to researchers from UPCI. The results of the research will be presented today at the American Society for Radiation Oncology (ASTRO) annual meeting in San Diego. The study, led by Dwight E. Heron, M.D., professor of otolaryngology and vice chairman ...

PITTSBURGH, Nov. 3 – Medicare patients in regions that spend the most on prescription medications are not necessarily getting better quality care, according to a new study of spending practices from the University of Pittsburgh Graduate School of Public Health (GSPH). The findings, published in the Nov. 3 Online First issue of the New England Journal of Medicine, reveal great variation across the country in both drug spending and the rate of inappropriate prescriptions for the elderly. Lead investigator Yuting Zhang, Ph.D., assistant professor of health economics at GSPH, ...

ANN ARBOR, Mich. — When Medicare policy changes led to reductions in reimbursement for hormonal treatment of prostate cancer, there was a sharp decline in its use among patients not likely to benefit from the treatment. But among patients for whom the therapy is clearly beneficial, doctors continued to prescribe it at the same rate, according to a new study. This finding suggests that financial reform of health care can reduce unnecessary care without impacting care to those patients most likely to benefit from a treatment. "We found that physicians respond to reimbursement, ...

Flexible smart materials that can manipulate light to shield objects from view have been much-theorised but now researchers in Scotland have made a practical breakthrough that brings the possibility of an invisibility cardigan – or any other item of invisibility clothing - one step closer. Two challenges to the creation of smart flexible materials that can cloak from visible light are making meta-atoms small enough to interact with visible light, and the fabrication of metamaterials that can be detached from the hard surfaces they are developed on to be used in more ...

November 4, 2010 – The autoimmune disease type 1 diabetes (T1D), also known as juvenile diabetes, is diagnosed in approximately 70,000 children worldwide per year. Genetics is increasingly being recognized as playing a significant role in susceptibility to the disorder, but outside a handful of genes, a clear understanding of the genetic architecture that underlies T1D has remained elusive. In a study published online today in Genome Research (www.genome.org), scientists have identified a novel gene associated with diabetes in mice that is revealing new clues about genomic ...

Researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco, and Pfizer Inc., have determined that two new compounds may be effective in treating both alcohol and nicotine dependence at the same time. In a paper published in the November 3, 2010 issue of Neuropsychopharmacology, the researchers showed that alcohol consumption in rodents was significantly decreased by two compounds that target neuronal nicotinic acetylcholine receptor (nAChR) subtype 34*. nAChRs are proteins found in the brain and broader ...

Remember the Star Wars scene in which R2D2 projects a three-dimensional image of a troubled Princess Leia delivering a call for help to Luke Skywalker and his allies? What used to be science fiction is now close to becoming reality thanks to a breakthrough in 3D holographic imaging technology developed at the University of Arizona College of Optical Sciences. A team led by optical sciences professor Nasser Peyghambarian developed a new type of holographic telepresence that allows the projection of a three-dimensional, moving image without the need for special eyewear ...

SAN FRANCISCO, CA – November 3, 2010—Scientists at the Gladstone Institute of Neurological Disease (GIND) have offered new information about the events that underlie the "spread" of Alzheimer's disease (AD) throughout the brain. The research, published in the November 4th issue of the journal Neuron, follows disease progression from a vulnerable brain region that is affected early in the disease to interconnected brain regions that are affected in later stages. The findings may contribute to design of therapeutic interventions, as targeting the brain region where AD originates ...

Many gene variants have been linked to autism, but how do these subtle changes alter the brain, and ultimately, behavior? Using a blend of brain imaging and genetic detective work, scientists at UCLA's David Geffen School of Medicine and Semel Institute for Neuroscience and Human Behavior are the first to illustrate how genetic variants rewire the brain. Published in the Nov. 3 online edition of Science Translational Medicine, their discovery offers the crucial missing physical evidence that links altered genes to modified brain function and learning. "This is a key ...

CAMBRIDGE, Mass. -- Humans have long taken advantage of the huge variety of medicinal compounds produced by plants. Now MIT chemists have found a new way to expand plants' pharmaceutical repertoire by genetically engineering them to produce unnatural variants of their usual products. The researchers, led by Associate Professor Sarah O'Connor, have added bacterial genes to the periwinkle plant, enabling it to attach halogens such as chlorine or bromine to a class of compounds called alkaloids that the plant normally produces. Many alkaloids have pharmaceutical properties, ...

Brain research over the past 30 years has shown that if a part of the brain controlling movement or sensation or language is lost because of a stroke or injury, other parts of the brain can take over the lost function – often as well as the region that was lost. New research at the University of California, Berkeley, shows that this holds true for memory and attention as well, though – at least for memory – the intact brain helps out only when needed and conducts business as usual when it's not. These results support the hypothesis that memory is not stored in one place, ...

Researchers at the University of Arizona (UA), Tucson, have developed a holographic system that can transmit a series of 3D images in near-real-time, a precursor to holographic videoconferencing. The system incorporates a novel, photorefractive polymer--one that can rapidly refresh holographic images and is scalable for production--coupled to a unique system for recording and transmitting 3D images of individuals and objects via Ethernet. Lead author Pierre-Alexandre Blanche and his colleagues from the university and Nitto Denko Technical Corp. of Oceanside, Calif., ...

Stroke is the leading cause of adult disability, due to the brain's limited capacity for recovery. Physical rehabilitation is the only current treatment following a stroke, and there are no medications available to help promote neurological recovery. Now, a new UCLA study published in the Nov. 11 issue of the journal Nature offers insights into a major limitation in the brain's ability to recover function after a stroke and identifies a promising medical therapy to help overcome this limitation. Researchers interested in how the brain repairs itself already know ...