INDIANAPOLIS – Failure to have a prescription filled can undermine medical treatment, result in increased health care costs and potentially have devastating results for the patient. An editorial in the Nov. 16 issue of the Annals of Internal Medicine highlights the problem and issues a call to action. In the editorial, "Prescription Abandonment: Another Path to Medication Nonadherence," Michael D. Murray, PharmD, MPH, a Regenstrief Institute, Inc. investigator and Purdue University professor of pharmacy practice, and Jeff Harrison, Ph.D., of the University of Auckland, ...

Montreal, November 16, 2010 – Disadvantaged kids are more likely to drop out of high school, become premature parents and raise their own children in poverty, according to an exhaustive new study from researchers at Concordia University and the University of Ottawa. Published in the International Journal of Behavioral Development, the investigation was the first to follow boys and girls over three decades to examine whether childhood aggression, social withdrawal and low socio-economic status could impact adult wellbeing. "Low socioeconomic status appears to have ...

A new study from the Swedish medical university Karolinska Institutet shows that asthma drugs are a potential treatment for aortic aneurysm. These drugs, which block cysteinyl-leukotrienes, could reduce the break down of vessel wall tissue and the dilation of the aortic wall, and thus the risk of its rupturing. This could both save lives and reduce the need for complicated and risky surgery. The results are presented in the scientific journal PNAS. Aortic aneurism is a life-threatening disease caused by the weakening of a section of the wall of the aorta, which then ...

HealthSpace, the internet-accessible personal health organiser developed as part of the National Programme for IT in the National Health Service, was significantly less popular than anticipated, a research team from the University of London has found. Instead of the predicted 5-10% of the population signing up, only 0.13% of those invited got as far as activating the full functionality of their personal health record, according to the study published on bmj.com today. Professor Trisha Greenhalgh from Barts and the London School of Medicine and Dentistry led the team ...

Researchers from the Group of Applied Artificial Intelligence (GIAA) on the Colmenarejo Campus of UC3M have presented this application at the latest Salón Internacional de Material Eléctrico y Electrónico, recently held in Madrid. The participants at the stand of Infaimon, the company which has collaborated on this project, had the opportunity to test this interface with a videogame operated simply by moving ones hands as if holding a virtual steering wheel. For this purpose, the scientists have employed a time of flight camera or TOF with which they capture in 3D user's ...

An open letter from 20 consultants and a patient group published on bmj.com today, calls on the prime minister to take action over a legal loophole that allows drug companies to make easy profits by licensing existing treatments for rare (orphan) diseases. They argue that the current situation concerning orphan drugs is not in the best interests of patients or the NHS and that the cost to the NHS is likely to be above £10m a year. The original purpose of this legislation was to encourage drug companies to conduct research into rare diseases and develop new treatments. ...

The metallic particles in the smoke emitted by fireworks pose a health risk, particularly to people who suffer from asthma. This is the conclusion of a study led by researchers from the Institute of Environmental Assessment and Water Research (IDAEA-CSIC), published this week in the Journal of Hazardous Materials. "The toxicological research has shown that many of the metallic particles in the smoke from fireworks are bio-reactive and can affect human health", Teresa Moreno, a researcher from the IDAEA (CSIC) and lead author of a study that has been published this week ...

ANN ARBOR, Mich. -- University of Michigan researchers have solved the structure of a protein that is integral to processes responsible for maintaining a healthy heart and nervous system. The protein structure in question is cystathionine beta-synthase, known as CBS. CBS uses vitamin B6 to make hydrogen sulfide (H2S), a gaseous signaling molecule that helps maintain a healthy heart and nervous system. H2S also induces a state of suspended animation or hibernation in animals by decreasing body temperature and lowering metabolic rate. The work to decode the structure ...

Arlington, Va. — New research being presented at the 2010 International Pharmaceutical Federation (FIP) Pharmaceutical Sciences World Congress (PSWC) in association with the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition will feature an inhalable dry powder antibiotic that when used alone or with current treatments may significantly reduce treatment for tuberculosis (TB) and multi-drug resistant TB. There are an estimated 9.4 million new cases of TB worldwide, according to the most recent statistics from the World Health Organization. ...

Whether a small cut with a fruit knife, a surgical wound or a major injury caused by a fall – the body's defense and repair system leaps into action and tries to close the wound as quickly as possible. Small injuries usually heal within a few days, but a gaping wound will take longer to heal, and an infection can take hold even after several days. Dressings protect the site of the injury but to check the wound they have to be removed. This can be painful for the patient and moreover it risks giving germs the chance to enter and cause infection. Scientists at the Fraunhofer ...

Hair clippings, cayenne pepper and raw eggs – these are just a few of the odd ingredients recommended to keep those pesky deer away from your backyard garden. But what about farmers who have hundreds of acres of Christmas trees to protect? North Carolina State University extension specialists have now found an effective, inexpensive alternative to available commercial products to keep the deer at bay. The NC State researchers, led by Jeff Owen, a Christmas-tree production specialist, are exploring the use of inexpensive, inedible food byproducts – such as dried blood ...

WEST LAFAYETTE, Ind. - Researchers have demonstrated a new imaging tool for rapidly screening structures called single-wall carbon nanotubes, possibly hastening their use in creating a new class of computers and electronics that are faster and consume less power than today's. The semiconducting nanostructures might be used to revolutionize electronics by replacing conventional silicon components and circuits. However, one obstacle in their application is that metallic versions form unavoidably during the manufacturing process, contaminating the semiconducting nanotubes. Now ...

WEST LAFAYETTE, Ind. - Researchers at Purdue University are studying the effects of fire on steel structures, such as buildings and bridges, using a one-of-a-kind heating system and a specialized laboratory for testing large beams and other components. Building fires may reach temperatures of 1,000 degrees Celsius, or more than 1,800 degrees Fahrenheit, said Amit Varma, a Purdue associate professor of civil engineering who is leading the work.g1 "At that temperature, exposed steel would take about 25 minutes to lose about 60 percent of its strength and stiffness," he ...

PITTSBURGH—A computer algorithm developed at Carnegie Mellon University matched living kidney donors with medically compatible transplant candidates late last month as the national Organ Procurement and Transplantation Network (OPTN), operated by the United Network for Organ Sharing (UNOS), began a national pilot program to increase the number of kidney paired-donation (KPD) transplants. The initial run of the computer matching process included just 43 kidney transplant candidates and 45 potential living donors, but a national KPD pool eventually could include as many ...

Three days of critical international discussion and debate, led by a panel of experts from the International Society of Clinical Densitometry (ISCD) and the International Osteoporosis Foundation (IOF), have served to clarify a number of important questions pertaining to the interpretation and use of FRAX® in clinical practice. The WHO Fracture Risk Assessment Tool (FRAX®), with models for some 26 countries, is an important new online tool that is being used by a steadily increasing number of physicians around the world. FRAX® is country-specific and calculates a patient's ...

Strokes, seizures and other neurological complications related to heart surgery account for "considerable morbidity and mortality," Loyola University Health System neurologists report in the November issue of the journal Hospital Practice. Other complications include delirium, central nervous system infections, pituitary gland problems, spinal cord or peripheral nerve injuries, residual effects of anesthesia and medication toxicity. Complications can involve any part of the central and peripheral nervous systems. "Neurologic complications are always a risk with cardiac ...

University of Alberta research has discovered a strong link between depression and risky sexual behaviours such as improper condom use, transactional sex and relationship violence among young people in South Africa. The research shows that depression is common among young South Africans, and could be making a significant contribution towards the HIV epidemic. As well, the researchers believe that depression could be contributing to risky sexual behaviours around the world, and that preventing or treating it may reduce the global burden of sexually transmitted diseases, ...

November 16, 2010 -- Scientists who study acoustics (the "science of sound") have over the years developed a variety of techniques to probe the hidden depths of oceans. This week, many of these acoustic researchers will come together to discuss how these technologies were used to monitor April's Deepwater Horizon oil spill, to present new data on the gusher's ecological impacts, and to highlight new techniques under development that could improve our ability to detect oil in ocean water. This special session will take place on November 17, 2010 at the 2nd Pan-American/Iberian ...

By examining the distinct wave patterns formed from complex biochemical reactions within the human body, diseased organs may be more effectively identified, says Zhengdong Cheng, associate professor in the Artie McFerrin Department of Chemical Engineering at Texas A&M University, who has developed a model that simulates how these wave patterns are generated. His findings, which appear in the October issue of the journal "Physical Review E," detail Cheng's work with a system designed to model cells in a biochemical environment, similar to what occurs inside the human body. His ...

CHAMPAIGN, Ill. — According to a popular hypothesis, grasses such as maize, sugar cane, millet and sorghum got their evolutionary start as a result of a steep drop in atmospheric carbon dioxide levels during the Oligocene epoch, more than 23 million years ago. A new study overturns that hypothesis, presenting the first geological evidence that the ancestors of these and other C4 grasses emerged millions of years earlier than previously established. The findings are published in the journal Geology. C4 plants are more efficient than C3 plants at taking up atmospheric ...

Two new studies have shown that a unique program in East Harlem that helps middle school students learn practical health skills and gain a better understanding of medical conditions, such as diabetes and hypertension, resulted in increased interest in college attendance and medical careers among the students who attended the program. The results were presented at the American Public Health Association (APHA) Annual Meeting this month in Denver. The MedStart Summer Enrichment Program was created in the summer of 2009 by Edward Chu and Melissa Schneiderman, two third-year ...

EAST LANSING, Mich. — Almost a third of cerebral malaria survivors developed epilepsy or other behavioral disorders in the most comprehensive study to date of the disease in African children, solidifying the link between malaria and neuropsychiatric disorders that affect hundreds of thousands of children. The research – led by Gretchen Birbeck, an associate professor of neurology and ophthalmology in Michigan State University's College of Osteopathic Medicine – appears in the current edition of The Lancet Neurology. Cerebral malaria is a severe form of malaria affecting ...

Using particles that are 1/100,000 the width of a human hair to deliver drugs to cells or assist plants in fighting off pests may sound like something out of a science fiction movie, but these scenarios may be a common occurrence in the near future. Carbon nanotubes, cylindrically shaped carbon molecules with a diameter of about 1 nanometer, have many potential applications in a variety of fields, such as biomedical engineering and medical chemistry. Proteins, nucleic acids, and drugs can be attached to these nanotubes and delivered to cells and organs. Carbon nanotubes ...

BERKELEY, Calif.—The Department of Energy's National Energy Research Scientific Computing Center (NERSC), already one of the world's leading centers for scientific productivity, is now home to the fifth most powerful supercomputer in the world and the second most powerful in the United States, according to the latest edition of the TOP500 list, the definitive ranking of the world's top computers. NERSC's newest supercomputer, a 153,408 processor-core Cray XE6 system, posted a performance of 1.05 petaflops (quadrillions of calculations per second) running the Linpack benchmark. ...

With the help of babies and more than 5,000 of their diapers, Emory University researchers have developed an accurate, noninvasive method to determine estrogen levels in infants. The method, previously used in nonhuman primates, will allow researchers to learn more about the association between estrogen levels in human infants and their long-term reproductive development as well as the development of sex-specific behaviors, such as toy preference or cognitive differences. What's more, the method will also allow researchers to look at how early disruption of the endocrine ...