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Subarachnoid hemorrhage more commonly caused by environmental factors than genes

2010-09-20
The large Nordic twin study investigating the heritability of subarachnothe role of genetic factors underlying the development of SAH suggests that the role of genetic factors underlying the development of SAH is less than previously believed. The prevalence of subarachnoid haemorrhage (SAH) is almost three times as high in Finland and Japan as among other nationalities. In Finland, some 1,000 cases are diagnosed every year, with almost half of the cases ending in death. SAH predominantly affects the working age population. Haemorrhage occurs when an aneurysm, a balloon-like ...

Apollo discovery tells a new story

Apollo discovery tells a new story
2010-09-20
A rare bronze signet ring with the impression of the face of the Greek sun god, Apollo, has been discovered at Tel Dor, in northern Israel, by University of Haifa diggers. "A piece of high-quality art such as this, doubtlessly created by a top-of-the-line artist, indicates that local elites developing a taste for fine art and the ability to afford it were also living in provincial towns, and not only in the capital cities of the Hellenistic kingdoms," explains Dr. Ayelet Gilboa, Head of the Department of Archaeology at the University of Haifa, who headed the excavations ...

New nanomaterial, shaped like Stars of David, discovered at Hebrew University

2010-09-20
Jerusalem, Sept. 19, 2010 -- A new type of nanoparticle resembling the six-pointed Star of David (Magen David) that is the symbol on the flag of Israel has been discovered by researchers at the Hebrew University of Jerusalem. (One nanometer is a billionth of a meter.) The discovery, the researchers say, may lead to new ways for sensing of glucose in diagnosing diabetes or provide a catalyst to capture the sun's energy and turn it into clean fuel. Their work, they further believe, greatly contributes to understanding how hybrid nanoparticles form. Hybrid nanoparticles ...

Novel electronic biosensing technology could facilitate new era of personalized medicine

Novel electronic biosensing technology could facilitate new era of personalized medicine
2010-09-20
The multi-welled microplate, long a standard tool in biomedical research and diagnostic laboratories, could become a thing of the past thanks to new electronic biosensing technology developed by a team of microelectronics engineers and biomedical scientists at the Georgia Institute of Technology. Essentially arrays of tiny test tubes, microplates have been used for decades to simultaneously test multiple samples for their responses to chemicals, living organisms or antibodies. Fluorescence or color changes in labels associated with compounds on the plates can signal ...

Russian activists risk arrest highlighting denial of HIV treatment

2010-09-20
MOSCOW and NEW YORK, 20 September – A group of Russian AIDS activists are charging that the Russian Ministry of Health is denying that there are drug stock-outs that prevent patients from starting or continuing treatment. "In this situation, people with HIV face a choice: to die quietly at home or try to attract the attention of the government and the media," said Alexey Yaskovich, a Russian activist from Novgorod. "Therefore, activists will continue to go to the streets of Moscow and hold public events dedicated to saving their lives." Activists continue to mount protests ...

Seasonal flu vaccine lowers risk of first heart attack

2010-09-20
The seasonal flu vaccine is associated with a 19% reduction in the rate of first heart attack and early vaccination in the fall further increases the benefits, found a study published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj091891.pdf. As heart attacks increase significantly in winter when pneumonia and flu are prevalent, it has been suggested there may be a link between respiratory infections and heart attacks. The study, by researchers from the United Kingdom, looked at 78 706 patients aged 40 years or ...

In pregnancy, a large waistline and high triglycerides: Early screen for gestational diabetes

2010-09-20
A large waistline and high triglyceride levels in pregnant women could be an early screening tool for gestational diabetes, according to a study published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100378.pdf. Gestational diabetes is a significant public health concern, with potential negative effects on women and their babies, yet tests to diagnose are costly, time-consuming and unpleasant for pregnant women. As well, results are not available until relatively late in pregnancy, at about six months. Previous ...

New driver of T cell leukemia growth

2010-09-20
NKX3.1, a protein that suppresses the development of prostate tumors, promotes the growth of a different type of tumor in the blood, according to an article published online on September 20 in the Journal of Experimental Medicine (www.jem.org). Paul-Henri Romeo and colleagues find that TAL1, a protein abundantly expressed in approximately 40% of patients with T cell acute lymphoblastic leukemia (T-ALL), drives expression of NKX3.1. Eliminating NKX3.1 halted the growth of TAL1-expressing T-ALL cells in culture and after injection into mice. It's not yet clear how ...

Preserving nerve cells in motor neuron disease

2010-09-20
A team of researchers, led by Scott Oakes, at the University of California, San Francisco, has identified a way to prevent symptom onset, weight loss, and paralysis and extend survival in a mouse model of amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease), providing a new avenue of research for the development of therapeutics for ALS and other motor neuron diseases. ALS and other motor neuron diseases are neurological disorders that selectively affect nerve cells that control voluntary muscle activities such as speaking, walking, breathing, swallowing, ...

JCI online early table of contents: Sept. 20, 2010

2010-09-20
EDITOR'S PICK: Preserving nerve cells in motor neuron disease A team of researchers, led by Scott Oakes, at the University of California, San Francisco, has identified a way to prevent symptom onset, weight loss, and paralysis and extend survival in a mouse model of amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease), providing a new avenue of research for the development of therapeutics for ALS and other motor neuron diseases. ALS and other motor neuron diseases are neurological disorders that selectively affect nerve cells that control voluntary ...

Lightweight true random number generators a step closer

2010-09-20
The widespread use of true random number generators (TRNGs) has taken a step closer following the creation of the most lightweight designs to date by researchers at Queen's University Belfast's Institute of Electronics, Communications and Information Technology (ECIT). Members of the Institute's cryptography research team have produced a series of circuits that are up to 50 per cent smaller than anything else currently available. Optimised for digital circuits, FPGA and ASIC, they push efficiency to the limit by using just one logic gate, one look-up table and four transistors ...

Protein may advance Parkinson's by preventing neurons from clearing debris

Protein may advance Parkinsons by preventing neurons from clearing debris
2010-09-20
A protein linked to Parkinson's disease may cause neurodegeneration by inhibiting autophagy—the process in which cells digest some of their contents—according to a study in the September 20 issue of the Journal of Cell Biology (www.jcb.org). Autophagy serves to clear a variety of toxic waste from cells, including misfolded proteins and defective mitochondria. These two types of cellular trash accumulate in neurons from Parkinson's patients, suggesting that autophagy could be impaired in these cells. A commonly amassed protein in Parkinson's disease is alpha-synuclein, ...

Magnetic attraction for fish, crabs?

Magnetic attraction for fish, crabs?
2010-09-20
SEATTLE – Super-sized electromagnetic coils are helping explain how aquatic life might be affected by renewable energy devices being considered for placement along America's coastal waters and in the nation's rivers. Scientists with the Department of Energy's Pacific Northwest National Laboratory are examining whether a variety of fish and invertebrates change their behavior during and after exposure to an electromagnetic field similar to those produced by marine and hydrokinetic power devices that capture energy from ocean waves, tides, currents and rivers. Research began ...

Female fish abandoned by males to raise offspring on their own

2010-09-20
Caring for children can be a tough job, particularly if you are a female cichlid fish. Native to the crater lakes of Nicaragua, cichlid fish look after their young by defending them against would-be predators. While male and female cichlid fish generally share parental responsibilities, research shows that this is not always the case. Conducted by an international team of researchers that included two biologists from Monash University, and published in the journal Behavioral Ecology and Sociobiology, new research has shown that male cichlid fish have a propensity ...

Secrets of birds' sexual signals revealed

Secrets of birds sexual signals revealed
2010-09-20
Patterned feathers, previously thought to be used only for camouflage in birds, can play an important role in attracting a mate and fending off rivals, a University of Melbourne study reveals. Ms Thanh-Lan Gluckman, co-author of the paper and Masters of Philosophy student from the Department of Zoology at the University of Melbourne, Australia, said this finding brought a new perspective to research in animal communication and evolution. "The implication of this study is that feathers don't need to be bright and showy to be used in sexual signalling and hence this changes ...

Protein behind development of immune system sentinels identified

Protein behind development of immune system sentinels identified
2010-09-20
A protein called PU.1 is essential for the development of dendritic cells, the sentinels of the immune system, Walter and Eliza Hall Institute researchers in Melbourne, Australia, have shown. Dendritic cells (DC) are immune cells that present proteins from foreign invaders, such as viruses, to the killer T cells of the immune system, allowing a full immune response to be mounted against the invaders. Researchers from the Immunology division have been studying dendritic cells and how different molecules regulate their development. Dr Li Wu said one of the molecules ...

Citizen scientist

2010-09-20
We are all scientists now, thanks to SETI@home, Galaxy Zoo, The Great Sunflower Project, Folding@home and counltess other projects that allow individuals to take part in scientific research directly or indirectly. In the case of SETI@home and Folding@home one shares one's computer CPU with the researchers, whereas Galaxy Zoo is more about active involvement with the classification of stellar objects in images of the night sky, for instance. Now, writing in the International Journal of Organisational Design and Engineering, US researchers have mapped out an approach to ...

Marine scientists unveil the mystery of life on undersea mountains

Marine scientists unveil the mystery of life on undersea mountains
2010-09-20
They challenge the mountain ranges of the Alps, the Andes and the Himalayas in size yet surprisingly little is known about seamounts, the vast mountains hidden under the world's oceans. Now in a special issue of Marine Ecology scientists uncover the mystery of life on these submerged mountain ranges and reveal why these under studied ecosystems are under threat. The bathymetry of our oceans is now resolved at a scale and detail unimaginable by early pioneers and recent estimates suggest that, globally, there may be up to 100,000 seamounts, yet despite best efforts less ...

Study gets measure of how best to prevent blood clots

2010-09-20
Treating hospital patients with thigh-length surgical stockings, rather than knee-high socks, can reduce life threatening blood clots, a new study suggests. Researchers found that knee-high stockings, which are similar to flight socks, do little in stroke patients to prevent deep vein thrombosis (DVT), a life threatening form of blood clot that can travel up into the heart and lungs, . The CLOTS (Clots in Legs Or sTockings after Stroke) study from the University of Edinburgh highlights that the clot rate in stroke patients was higher among those fitted with the shorter ...

The Amazon rainforest -- a cloud factory

The Amazon rainforest -- a cloud factory
2010-09-20
The forest in the Amazon Basin produces its own rain. During the wet season, aerosol particles, which serve to condensate clouds and precipitation here, mainly consist of organic material. These aerosols are released by the rainforest itself. This has been demonstrated by scientists from the Max Planck Institute for Chemistry in Mainz, who are now able to draw conclusions about the mechanisms of this ecosystem: the high content of organic material indicates that the Amazon Basin acts as a largely self-contained biogeochemical reactor during the rainy season. The results ...

Vigilant camera eye

Vigilant camera eye
2010-09-20
»Goal, goal, goal!« fans in the stadium are absolutely ecstatic, the uproar is enormous. So it's hardly surprising that the security personnel fail to spot a brawl going on between a few spectators. Separating jubilant fans from scuffling hooligans is virtually impossible in such a situation. Special surveillance cameras that immediately spot anything untoward and identify anything out of the ordinary could provide a solution. Researchers from the Fraunhofer Institute for Applied Information Technology FIT in Sankt Augustin have now developed such a device as part of the ...

Image sensors for extreme temperatures

Image sensors for extreme temperatures
2010-09-20
More and more car manufacturers are equipping their vehicles with image sensors – e.g. to register the presence of pedestrians or vehicles in the blind spot or to detect obstacles when parking. The sensors must be able to function in extremely high temperatures and in blazing sunlight. If they are installed behind the rear view mirror or on the instrument panel, for example, they can get very hot. The Fraunhofer Institute for Microelectronic Circuits and Systems IMS in Duisburg has developed a CMOS (complementary metal oxide semiconductor) image sensor for an industrial ...

Taking the pulse of coral reefs

Taking the pulse of coral reefs
2010-09-20
Healthy reefs with more corals and fish generate predictably greater levels of noise, according to researchers working in Panama. This has important implications for understanding the behaviour of young fish, and provides an exciting new approach for monitoring environmental health by listening to reefs. Contrary to Jacques Cousteau's 'Silent World', coral reefs are surprisingly noisy places, with fish and invertebrates producing clicks and grunts which combine to produce cacophonies of noise. Each reef is subtly different depending on the size and composition of the ...

Earth's highest coastal mountain on the move

Earths highest coastal mountain on the move
2010-09-20
The rocks of Colombia's Sierra Nevada de Santa Marta—the highest coastal mountain on Earth—tell a fascinating tale: The mountain collides and then separates from former super-continents. Volcanoes are born and die. The mountain travels from Peru to northern Colombia and finally rotates in a clockwise direction to open up an entirely new geological basin. Smithsonian scientists were part of a four-year project to study Santa Marta's geological evolution. Their findings are published in the October 2010 special issue of the Journal of South American Earth Sciences. The study ...

Returning troops face both physical and mental challenges

2010-09-20
Is the US health system comprehensively meeting the needs of returning veterans? With the recent attention to mental illness in returning soldiers, and post-traumatic stress disorder (PTSD) in particular, little research has focused on the medical care needs of those returning from Operation Enduring Freedom/Operation Iraqi Freedom, according to Dr. Susan Frayne, from the VA Palo Alto Health Care System and Stanford University, and colleagues. Their research highlights that veterans suffering from PTSD also suffer more medical illnesses than do those with no mental health ...
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