Adults with congenital heart disease are more likely to suffer heart-focused anxiety – a fear of heart-related symptoms and sensations – if their parents were overprotective during their childhood and adolescence. Dr. Lephuong Ong from Orion Health Services in Vancouver, and colleagues from University Health Network and York University in Toronto, Canada, suggest that health care professionals could encourage greater independence for adolescents and adults with congenital heart disease to improve their psychosocial adjustment. Dr. Ong's work1 is published online in Springer's ...

Animals react to infections in a number of ways. Among the first is the production of cell factors such as interferons and IL-1beta. Interferons have several functions, including activating a series of intracellular signals such as Tyk2 (Tyrosine kinase 2), while IL-1beta is important for the induction of inflammation, which helps directly to protect the body against attack. However, inflammation must be kept tightly in check as it may also harm the body. Cells control IL-1beta activity in a number of ways, regulating not only the amount of messenger RNA (mRNA) that encodes ...

A new approach to evaluating a person's risk of cardiovascular disease, stroke, high blood pressure, or heart failure is reported this month in the International Journal of Data Mining, Modelling and Management. The technique uses fuzzy logic to teach a neural network computer program to analyze patient data and spot correlations that can be translated into a risk factor for an individual. Khanna Nehemiah of the Anna University Chennai, India, and colleagues have developed a medical diagnostic system for predicting the severity of cardiovascular disease based on combining ...

WEST LAFAYETTE, Ind. - Researchers at Purdue University have developed a facility aimed at learning precisely how coal and biomass are broken down in reactors called gasifiers as part of a project to strengthen the scientific foundations of the synthetic fuel economy. "A major focus is to be able to produce a significant quantity of synthetic fuel for the U.S. air transportation system and to reduce our dependence on petroleum oil for transportation," said Jay Gore, the Reilly University Chair Professor of Combustion Engineering at Purdue. The research is part of work ...

Montreal September 15, 2010 – The human quest for longer life may be one step closer, thanks to research from Concordia University. Published in the journal Aging, a new study is the first to identify the role of a bile acid, called lithocholic acid (LCA), in extending the lifespan of normally aging yeast. The findings may have significant implications for human longevity and health, as yeast share some common elements with people. "Although we found that LCA greatly extends yeast longevity, yeast do not synthesize this or any other bile acid found in mammals," says ...

AUSTIN, Texas—The development of new organic batteries—lightweight energy storage devices that work without the need for toxic heavy metals—has a brighter future now that chemists have discovered a new way to pass electrons back and forth between two molecules. The research is also a necessary step toward creating artificial photosynthesis, where fuel could be generated directly from the sun, much as plants do. University of Texas at Austin chemists Christopher Bielawski and Jonathan Sessler led the research, which was published in Science. When molecules meet, they ...

U.S. Department of Agriculture (USDA) scientists and their partners have announced the preliminary release of the sequenced genome of the cacao tree, an achievement that will help sustain the supply of high-quality cocoa to the $17 billion U.S. chocolate industry and protect the livelihoods of small farmers around the world by speeding up development, through traditional breeding techniques, of trees better equipped to resist the droughts, diseases and pests that threaten this vital agricultural crop. The effort is the result of a partnership between USDA's Agricultural ...

Want to know how a Japanese person is feeling? Pay attention to the tone of his voice, not his face. That's what other Japanese people would do, anyway. A new study examines how Dutch and Japanese people assess others' emotions and finds that Dutch people pay attention to the facial expression more than Japanese people do. "As humans are social animals, it's important for humans to understand the emotional state of other people to maintain good relationships," says Akihiro Tanaka of Waseda Institute for Advanced Study in Japan. "When a man is smiling, probably he is happy, ...

Scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio have found a gene that causes high levels of bad cholesterol to accumulate in the blood as a result of a high-cholesterol diet. Researchers studied a strain of laboratory opossums developed at SFBR that has normal blood levels of "bad" low-density lipoprotein (LDL) cholesterol when fed a standard low-cholesterol diet, but extremely elevated levels of LDL cholesterol when fed a high-cholesterol diet. These high-responding opossums are used to identify the genes and the underlying mechanisms ...

BLOOMINGTON, Ind. -- A first draft of the cacao genome is complete, a consortium of academic, governmental, and industry scientists announced today. Indiana University Bloomington scientists performed much of the sequencing work, which is described and detailed at http://www.cacaogenomedb.org/, the official website of the Cacao Genome Database project. Despite being led and funded by a private company, Mars Inc., Cacao Genome Database scientists say one of their chief concerns has been making sure the Theobroma cacao genome data was published for all to see -- especially ...

A new technology for removing water from ultrafine coal slurry has been successfully tested at the commercial scale at an operating coal cleaning plant. The technology offers the possibility of reducing the coal slurry impoundment problem from the source. A peer-reviewed paper on this new technology was presented Sept. 15 at the 13th Australian Coal Preparation Society Conference, Cairns, Queensland. Cleaning coal after it has been mined is done with water. The bulk of the coal mined is relatively coarse in size and, therefore, can be readily washed of impurities and ...

BOSTON—Cancer patients who die in the hospital or an intensive care unit have worse quality of life at the end-of-life, compared to patients who die at home with hospice services, and their caregivers are at higher risk for developing psychiatric illnesses during bereavement, according to a study by researchers at Dana-Farber Cancer Institute. One striking finding of the study, reported in the September 13th issue of the Journal of Clinical Oncology, was that bereaved caregivers of patients who died in an intensive care unit (ICU) were five times more likely to be diagnosed ...

Reducing the delivery of nutrients to the Chesapeake Bay is one of the most important components of restoration efforts to achieve a healthy Bay ecosystem. The USGS has developed a new method for tracking the progress toward reducing nitrogen and phosphorus delivery from the watershed to the Bay. "The public and public officials care deeply about progress towards clean water goals for the Chesapeake Bay and other impaired waters of the Nation," said Robert Hirsch, USGS Research Hydrologist who led the development of this new method. "We developed the new technique and ...

The number of times our cells can divide is dictated by telomeres, stretches of DNA at the tips of our chromosomes. Understanding how telomeres keep our chromosomes – and by extension, our genomes – intact is an area of intense scientific focus in the fields of both aging and cancer. Now, scientists at The Wistar Institute have published the first detailed report on the structure and function of a crucial domain in the protein known as Cdc13, which sustains telomeres by clamping to DNA and recruiting replicating enzymes to the area. While the nature of this portion of ...

Hurricane Igor is a monster hurricane in terms of strength and size. To get a perspective on its size, it is the same distance from one end of the storm to the other as it is from Boston, Mass. to Richmond, Va., some 550 miles. That's a 10-hour drive from one end to the other, and NASA satellites captured that entire distance in one image. Because Hurricane Igor is a large storm and even if Igor doesn't make a direct landfall in Bermuda, the extent of the winds (the wind field) is so large that the National Hurricane Center noted that Bermuda can be buffeted by winds ...

Scientists are reporting discovery of the biological secrets that enable plants growing near the Chernobyl Nuclear Power Plant to adapt and flourish in highly radioactive soil — legacy of the 1986 nuclear disaster in the Ukraine. Their study, which helps solve a long-standing mystery, appears in ACS' Environmental Science & Technology, a semi-monthly journal. Martin Hajduch and colleagues note that plants have an unexpected ability to adapt to an environment contaminated with radiation following the April 26, 1986 accident at Chernobyl. Their previous research, for example, ...

NASA's Aqua satellite captured the birth of Tropical Storm Karl on Sept. 14 as it passed overhead at 3:05 p.m. EDT in the Caribbean. This morning, Karl made landfall in the east coast of the Yucatan Peninsula, Mexico. By 5 p.m. EDT on Sept. 14, System 92L intensified quickly in the western Caribbean and became the thirteenth tropical depression that quickly fired up into Tropical Storm Karl. NASA's Aqua satellite was flying overhead at 3:05 p.m. EDT and the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument captured a visible image of Karl as he was rapidly ...

Carbon nanotubes — those tiny particles poised to revolutionize electronics, medicine, and other areas — are much bigger in the strength department than anyone ever thought, scientists are reporting. New studies on the strength of these submicroscopic cylinders of carbon indicate that on an ounce-for-ounce basis they are at least 117 times stronger than steel and 30 times stronger than Kevlar, the material used in bulletproof vests and other products. The findings, which could expand commercial and industrial applications of nanotube materials, appear in the monthly journal ...

CHICAGO --- The millions of middle-aged and older adults who suffer from insomnia have a new drug-free prescription for a more restful night's sleep. Regular aerobic exercise improves the quality of sleep, mood and vitality, according to a small but significant new study from Northwestern Medicine. The study is the first to examine the effect of aerobic exercise on middle-aged and older adults with a diagnosis of insomnia. About 50 percent of people in these age groups complain of chronic insomnia symptoms. The aerobic exercise trial resulted in the most dramatic ...

Scientists reported new evidence on the effectiveness of that old folk remedy — cranberry juice — for urinary tract infections at the ACS' 240th National Meeting. "A number of controlled clinical trials — these are carefully designed and conducted scientific studies done in humans — have concluded that cranberry juice really is effective for preventing urinary tract infections," said Terri Anne Camesano, Ph.D., who led the study. "That has important implications, considering the size of the problem and the health care costs involved." Estimates suggest that urinary tract ...

Tests of a potential vaccine against "Ich" — the dreaded "white-spot" disease that plagues fish in commercial fish farms, public aquariums, pet fish retail outlets, and home aquariums — are raising hopes for finally controlling the disease, scientists reported at the 240th National Meeting of the American Chemical Society. "Outbreaks of the parasitic disease caused by Ichthyophthirius (Ich) can result in losses of 50-100 percent of fish," Dehai Xu, Ph.D., said. "The disease is very common, and almost every home fish hobbyist has encountered it. Once the parasite infects ...

Funding from an anonymous wealthy family has been the secret to progress, at long last, in developing drugs that show promise for helping millions of people worldwide with Fragile X syndrome, the most common genetic cause of autism. That's the topic of a fascinating article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine. C&EN Senior Editor Lisa Jarvis notes that until recent interest from big pharmaceutical companies, a small drug company in Cambridge, Mass. named Seaside Therapeutics was virtually the only company trying to develop ...

Rapid improvements in facial-recognition software mean airport security workers might one day know with near certainty whether they're looking at a stressed-out tourist or staring a terrorist in the eye. A research team led by Dr. Alice O'Toole, a professor in The University of Texas at Dallas' School of Behavioral and Brain Sciences, is evaluating how well these rapidly evolving recognition programs work. The researchers are comparing the rates of success for the software to the rates for non-technological, but presumably "expert" human evaluation. "The government ...

SCOTTSDALE, Ariz. (Sept. 14, 2010) – A new investigational drug designed to penetrate and attack pancreatic cancer cells has been administered to a patient for the first time ever at the Virginia G. Piper Cancer Center at Scottsdale Healthcare. ASG-5ME is a potent, targeted compound designed to selectively kill cancer cells, says Daniel Von Hoff, MD, a principal investigator in the Phase I clinical trial. Pancreatic cancer is a fast-growing and difficult to treat form of cancer, and is the fourth leading cause of cancer death in the United States. "ASG-5ME is intended ...

SALT LAKE CITY—The Intermountain West is renowned for the beauty of its towering mountains and high deserts, but according to new research from an investigator with the University of Utah Brain Institute the region's lofty altitudes significantly influence a deadly problem: the high prevalence of suicides in this part of the country. In the Sept. 15, 2010, online edition of the American Journal of Psychiatry, Perry F. Renshaw, M.D., Ph.D., MBA, professor of psychiatry at the U School of Medicine and an investigator with Utah Science Technology and Research (USTAR) initiative, ...