Whether doctors have knowledge of guidelines or not appears to be unsuitable as an indicator of how guidelines are being put into practice in the clinical routine. Taking the case of treatment by primary care physicians of three target diseases – hypertension, heart failure, and chronic coronary heart disease – in the current edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2011; 108(5) 61-9) Ute Karbach and her coauthors investigate the relationship for physicians between knowing the guidelines and acting in compliance with them. Data on 437 physicians' ...

If you want to improve the way you eat, the best way to do so is to both make an action plan and visualize yourself carrying it out, according to McGill researchers. "Telling people to just change the way they eat doesn't work; we've known that for a while," says Bärbel Knäuper of McGill's Department of Psychology."But research has shown that if people make a concrete plan about what they are going to do, they are better at acting on their intentions. What we've done that's new is to add visualization techniques to the action plan." In a study recently published in ...

Scientists at Trinity College Dublin have made an important discovery concerning how fledgling cancer cells self-destruct, which has the potential of impacting on future cancer therapies. The Trinity research group, led by Smurfit Professor of Medical Genetics, Professor Seamus Martin and funded by Science Foundation Ireland, has just published their findings in the internationally renowned journal, Molecular Cell. Professor Martin's team has discovered how a process called 'autophagy' – which literally means 'self-eating' – plays an important role in safeguarding against ...

Through his participation, the research team from Bochum, Duisburg-Essen, and Hamburg now has succeeded in an energy-state occupancy readout of those artificial atoms – using common interfaces to classic computers. This is a big step towards the application of such systems. They report about their findings in Nature Communications. One million instead of individual atoms In principle, the spin of electrons in individual atoms can be read-out, but the minuteness of the signals and the difficulty of localising individual atoms limit this technology to highly specialised ...

New research enhances the current knowledge of how human immunodeficiency virus type-1 (HIV-1), which causes AIDS, controls the cell cycle of cells that it infects. The new findings may shed light on how the virus reactivates after entering a dormant state, called latency. "As we better understand the biological events that revive HIV from latency, we hope to devise ways to eventually intervene in this process with better treatments for people with HIV infection," said study leader Terri H. Finkel, M.D., Ph.D., chief of Rheumatology at The Children's Hospital of Philadelphia. Finkel ...

This release is available in Spanish, French and German. The world watched in horror as Taliban fanatics ten years ago blew up the two gigantic Buddha statues that had since the 6th century looked out over the Bamiyan Valley in what is now Afghanistan. Located on the Silk Road, until the 10th century the 55 and 38 meter tall works of art formed the centerpiece of one of the world's largest Buddhist monastic complexes. Thousands of monks tended countless shrines in the niches and caves that pierced a kilometer-long cliff face. Since the suppression of the Taliban ...

Despite innumerable studies on lung cancer, many aspects of the disease have yet to be understood, including the role played by the retinoblastoma-related protein Rb2/p130 in the evolution of the disease. In a new study, researchers from the Sbarro Health Research Organization Center for Biotechnology Research (SHRO), a cancer, cardiovascular and diabetes research center located in the College of Science and Technology at Temple University in Philadelphia, PA, and at the University of Siena in Siena, Italy examined mechanisms that control Rb2/p130 gene expression in ...

New Rochelle, NY, February 25, 2011—Hashimoto's thyroiditis (HT), an inflammatory disorder of the thyroid, is the most common cause of hypothyroidism, but a study has suggested that even when thyroid function is normal, HT may increase symptoms and decrease quality of life, as described in an article in Thyroid, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). Thyroid is the Official Journal of the American Thyroid Association (ATA). The article is available free online at www.liebertpub.com/thy Hashimoto's thyroiditis most commonly affects ...

Imagine that you're in a bar and you accidentally knock over your neighbor's beer. He turns around and stares at you, looking for confrontation. Do you buy him a new drink, or do you try to outstare him to make him back off? New research published in Psychological Science, a journal of the Association for Psychological Science, suggests that the dominance behavior exhibited by staring someone down can be reflexive. Our primate relatives certainly get into dominance battles; they mostly resolve the dominance hierarchy not through fighting, but through staring contests. ...

SAN ANTONIO, Texas, U.S.A. (Feb. 25, 2011) — The death of insulin-producing beta cells in the pancreas is a core defect in diabetes. Scientists in Italy and Texas now have discovered a new way that these cells die — by toxic imbalance of a molecule secreted by other pancreatic cells. "Our study shows that neighboring cells called alpha cells can behave like adversaries for beta cells. This was an unexpected finding," said Franco Folli, M.D., Ph.D., professor of medicine/diabetes at The University of Texas Health Science Center at San Antonio. He is co-lead author on the ...

Scientists are unravelling the environmental changes that took place around the Arctic during an exceptional episode of ancient global warming. Newly published results from a high-resolution study of sediments collected on Spitsbergen represent a significant contribution to this endeavour. The study was led by Dr Ian Harding and Prof John Marshall of the University of Southampton's School of Ocean and Earth Science (SOES), based at the National Oceanography Centre, Southampton. Around 56 million years ago there was a period of global warming called the Paleocene–Eocene ...

Researching animals in the wild can be challenging, especially if it involves a rare or elusive species like the giant panda or the clouded leopard. To remedy this, scientists rely heavily on camera traps—automated cameras with motion sensors. Left to photograph what passes in front of them, the cameras record the diversity and very often the behavior of animals around the world. The Smithsonian has brought together more than 202,000 wildlife photos from seven projects conducted by Smithsonian researchers and their colleagues into one searchable website, siwild.si.edu. ...

Botulism is a rare disease and recurrent botulism even more rare. However, in California, recurrent wound botulism among injection drug users has been on the rise and makes up three-quarters of reported cases in the United States. A new study published in Clinical Infectious Diseases and currently available online (http://cid.oxfordjournals.org/content/early/2011/02/07/cid.cir005.full) examines this problem. From 1993 through 2006, 17 injection drug users were identified within the surveillance system of the California Department of Public Health for having recurrent ...

COLUMBIA, Mo. - Nearly 16 million Americans will be diagnosed with Alzheimer's disease or another type of dementia by 2050, according to the Alzheimer's Association. Symptoms include mood and behavior changes, disorientation, memory loss and difficulty walking and speaking. The effects of anti-dementia drugs on patients' emotions and behaviors are inconsistent. Now, University of Missouri researchers have found that participation in TimeSlips, a drug-free, creative storytelling intervention, improves communication skills and positive affect in persons with dementia. TimeSlips ...

February 25, 2011 -- Nearly one in eleven (8.6%) preschool children in the U.S. has been diagnosed with asthma and in some inner city neighborhoods, the figure is closer to one in seven. But, few asthma management programs are designed for parents of preschool children. The Asthma Basics for Children (ABC) program, established by Columbia University's Mailman School of Public Health and a coalition of community service organizations, educators, parenting programs, and community pediatric providers, addressed this need with a multi-layered approach that offers educational ...

Literature and films have left us with vivid images of the grasshopper plagues that devastated the Great Plains in the 1870s. Although commonly referred to as grasshoppers, the infestations were actually by Rocky Mountain locusts. The Rocky Mountain locust became extinct in 1902, but their cousins, grasshoppers and Mormon crickets, today still cause an estimated $1.5 billion (2005 U.S. dollars) in damage to grazing lands in the American West. A long-running research project directed by University of Notre Dame biologist Gary Belovsky, who also is director of the Notre ...

ARLINGTON, Va.-Successfully taking a small radio receiver intended for space applications and creating a full-featured radio frequency system, initially designed for a Marine Corps unmanned aircraft, would not have been possible without the integrated effort of three naval entities. The Software Reprogrammable Payload (SRP), a collaborative effort between the Office of Naval Research, the Naval Research Laboratory and Marine Corps aviation, is currently targeted for the Shadow unmanned aircraft system (UAS). Based on the successful development of SRP, Marine Corps ...

HOUSTON - Like a bounty hunter returning escapees to custody, a cancer-fighting gene converts organ cells that change into highly mobile stem cells back to their original, stationary state, researchers report online at Nature Cell Biology. This newly discovered activity of the p53 gene offers a potential avenue of attack on breast cancer stem cells thought to play a central role in progression and spread of the disease, according to scientists at The University of Texas MD Anderson Cancer Center. Long known for monitoring DNA damage and forcing defective cells to kill ...

Rice University scientists and their colleagues have found that when growing corn crops for ethanol, more means less. A new paper in today's online edition of the American Chemical Society's journal Environmental Science and Technology shows how farmers can save money on fertilizer while they improve their production of feedstock for ethanol and alleviate damage to the environment. The research has implications for an industry that has grown dramatically in recent years to satisfy America's need for energy while trying to cut the nation's reliance on fossil fuels. The ...

Hawaii growers can now export more fruits and vegetables to the U.S. mainland, thanks to technology advanced by U.S. Department of Agriculture (USDA) scientists and cooperators. Delicious tropical fruits and vegetables such as papaya, rambutan, longan, dragon fruit and purple-fleshed sweet potato are gaining popularity in the continental United States. But just five years ago, it would have been difficult to find these tropical delicacies in grocery stores. That's because strict quarantine restrictions and phytosanitary measures are in place to ensure agricultural pests ...

In a finding that once again displays the power of the female, UCSF neuroscientists have discovered that teenage male songbirds, still working to perfect their song, improve their performance in the presence of a female bird. The finding sheds light on how social cues can impact the process of learning, the researchers said, and, specifically, could offer insights into the way humans learn speech and other motor skills. It also could inform strategies for rehabilitating people with motor disorders or brain injuries. The study was reported in a recent early online edition ...

Using tiny spheres of radioactive liquid to guide surgeons as they remove potentially cancerous material in the lungs is safe and more effective than other techniques, Italian researchers report at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011, Lugano, Switzerland. Dr Luca Bertolaccini, Dr Alberto Terzi and colleagues from Santa Croce e Carle Hospital in Cuneo, Italy, studied a technique known as radio-guided surgery in 19 patients. Each of the patients had been found to have 'single pulmonary nodules' in their lungs. Single ...

The targeted cancer drug erlotinib has comparable efficacy to chemotherapy, and is better tolerated, in hard-to-treat cases where a patient's cancer has progressed quickly after treatment with first-line therapy, the results of a new phase III trial show. Dr Tudor Ciuleanu from the Institute of Oncology Ion Chiricuta, Cluj-Napoca, Romania, reported this finding from the international TITAN study at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011, Lugano, Switzerland. "The TITAN study is the first trial to evaluate whether ...

Famed especially for the excellence of its peacekeepers and ice hockey players, Canada's water experts are now increasingly needed to help countries elsewhere brace for drought, flood and unsafe water problems looming on a 15 to 20 year horizon. Within a single generation, recent studies show, water demand in many countries will exceed supply by an estimated 40%, with one-third of humanity having half the water required for life's basics. In flood-prone places, meanwhile, catastrophic flood events normally expected once a century - similar to those recently witnessed ...

PROVIDENCE, R.I. [Brown University] — Freshmen on the eve of finals and graduate students staring down a thesis committee may not feel this way, but the privilege of obtaining an advanced education correlates with decades of lower blood pressure, according to a study led by a public health researcher at Brown University. The benefit appears to be greater for women than for men. Eric Loucks, assistant professor of community health, says the analysis of nearly 4,000 patient records from the 30-year Framingham Offspring Study may help explain a widely documented association ...