PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Assessment of neutrophil extracellular traps in coronary thrombus of case series of patients with COVID-19

2021-01-02
(Press-News.org) What The Study Did: Severe COVID-19 is characterized by the intense formation of neutrophil extracellular traps (NETs), leading to the blockage of microvessels, as shown in pulmonary samples. The occurrence of ST-elevated myocardial infarction (STEMI) is a serious cardiac manifestation of COVID-19; the intrinsic mechanism of coronary thrombosis appears to still be unknown. This case series report of five patients sought to determine the role of NETs in coronary thrombosis in patients with COVID-19.

Authors: Ana Blasco, M.D., Ph.D., of the Hospital Universitario Puerta de Hierro-Majadahonda in Madrid, Spain, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamacardio.2020.7308)

Editor's Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

INFORMATION:

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time
https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2020.7308?guestAccessKey=06999ae7-15ab-4b58-a4ce-b8adb0afe5dd&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=122920



ELSE PRESS RELEASES FROM THIS DATE:

Protein twist and squeeze confers cancer drug resistance

2021-01-02
In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years. Now, his team has published a review in the journal FEBS Letters, summarizing what they have learned following years of research on this and other ATP-binding cassette (ABC) transporter proteins. ABC transporter proteins are very similar across species and have various ...

Large transporter protein linked to schizophrenia

Large transporter protein linked to schizophrenia
2021-01-02
Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens. Now, Kazumitsu Ueda of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have provided evidence that mice with disrupted ABCA13 protein demonstrate a hallmark behaviour of schizophrenia. The team investigated ABCA13's functions and published their findings in the Journal of Biological Chemistry. ABCA13 belongs to a family of cellular transporter proteins called ATP-binding ...

Brain imaging predicts PTSD after brain injury

2021-01-02
Philadelphia, December 29, 2020 - Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder brought on by physical and/or psychological trauma. How its symptoms, including anxiety, depression and cognitive disturbances arise remains incompletely understood and unpredictable. Treatments and outcomes could potentially be improved if doctors could better predict who would develop PTSD. Now, researchers using magnetic resonance imaging (MRI) have found potential brain biomarkers of PTSD in people with traumatic brain injury (TBI). The study appears in ...

Imaging the twilight zone

Imaging the twilight zone
2021-01-02
What happens in the brain when our conscious awareness fades during general anesthesia and normal sleep? Finnish scientists studied this question with novel experimental designs and functional brain imaging. They succeeded in separating the specific changes related to consciousness from the more widespread overall effects, and discovered that the effects of anesthesia and sleep on brain activity were surprisingly similar. These novel findings point to a common central core brain network fundamental for human consciousness. Explaining the biological basis of human ...

Order and disorder in crystalline ice explained

2021-01-02
A fascinating substance with unique properties, ice has intrigued humans since time immemorial. Unlike most other materials, ice at very low temperature is not as ordered as it could be. A collaboration between the Scuola Internazionale Superiore di Studi Avanzati (SISSA), the Abdus Salam International Centre for Theoretical Physics (ICTP), the Institute of Physics Rosario (IFIR-UNR), with the support of the Istituto Officina dei Materiali of the Italian National Research Council (CNR-IOM), made new theoretical inroads on the reasons why this happens and on the way in which some of the missing order can be recovered. In that ordered state the team ...

Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease

Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease
2021-01-02
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in The Journal of the American Society of Nephrology. Chronic kidney disease (CKD) affects approximately ten percent of the global population. Hypertension is ...

Detective work in theoretical physics

Detective work in theoretical physics
2021-01-02
Scientific articles in the field of physics are mostly very short and deal with a very restricted topic. A remarkable exception to this is an article published recently by physicists from the Universities of Münster and Düsseldorf. The article is 127 pages long, cites a total of 1075 sources and deals with a wide range of branches of physics - from biophysics to quantum mechanics. The article is a so-called review article and was written by physicists Michael te Vrugt and Prof. Raphael Wittkowski from the Institute of Theoretical Physics and the Center for Soft Nanoscience at the University of Münster, together with ...

In plants, channels set the rhythm

2021-01-02
Although plants are anchored to the ground, they spend most of their lifetime swinging in the wind. Like animals, plants have 'molecular switches' on the surface of their cells that transduce a mechanical signal into an electrical one in milliseconds. In animals, sound vibrations activate 'molecular switches' located in the ear. Scientists from the CNRS, INRAE, Ecole Polytechnique, Université Paris-Saclay and Université Clermont-Auvergne (1) have found that in plants, rapid oscillations of stems and leaves ...

Sugars influence cell-to-surface adhesion

Sugars influence cell-to-surface adhesion
2021-01-02
How can cells adhere to surfaces and move on them? This is a question which was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China). The researchers used the green alga Chlamydomonas reinhardtii as their model organism. They manipulated the alga by altering the sugar modifications in proteins on the cell surface. As a result, they were able to alter the cellular surface adhesion, also known as adhesion force. The results have now been published in the ...

A single gene 'invented' haemoglobin several times

A single gene invented haemoglobin several times
2021-01-02
Thanks to the marine worm Platynereis dumerilii, an animal whose genes have evolved very slowly, scientists from CNRS, Université de Paris and Sorbonne Université, in association with others at the University of Saint Petersburg and the University of Rio de Janeiro, have shown that while haemoglobin appeared independently in several species, it actually descends from a single gene transmitted to all by their last common ancestor. These findings were published on 29 December 2020 in BMC Evolutionary Biology. Having red blood is not peculiar to humans or mammals. ...

LAST 30 PRESS RELEASES:

How rice plants tell head from toe during early growth

Scientists design solar-responsive biochar that accelerates environmental cleanup

Construction of a localized immune niche via supramolecular hydrogel vaccine to elicit durable and enhanced immunity against infectious diseases

Deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy

DHL-11, a novel prieurianin-type limonoid isolated from Munronia henryi, targeting IMPDH2 to inhibit triple-negative breast cancer

Discovery of SARS-CoV-2 PLpro inhibitors and RIPK1 inhibitors with synergistic antiviral efficacy in a mouse COVID-19 model

Neg-entropy is the true drug target for chronic diseases

Oxygen-boosted dual-section microneedle patch for enhanced drug penetration and improved photodynamic and anti-inflammatory therapy in psoriasis

Early TB treatment reduced deaths from sepsis among people with HIV

Palmitoylation of Tfr1 enhances platelet ferroptosis and liver injury in heat stroke

Structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity

Therapeutic drug monitoring of biologics in inflammatory bowel disease: An evidence-based multidisciplinary guidelines

New global review reveals integrating finance, technology, and governance is key to equitable climate action

New study reveals cyanobacteria may help spread antibiotic resistance in estuarine ecosystems

Around the world, children’s cooperative behaviors and norms converge toward community-specific norms in middle childhood, Boston College researchers report

How cultural norms shape childhood development

University of Phoenix research finds AI-integrated coursework strengthens student learning and career skills

Next generation genetics technology developed to counter the rise of antibiotic resistance

Ochsner Health hospitals named Best-in-State 2026

A new window into hemodialysis: How optical sensors could make treatment safer

High-dose therapy had lasting benefits for infants with stroke before or soon after birth

‘Energy efficiency’ key to mountain birds adapting to changing environmental conditions

Scientists now know why ovarian cancer spreads so rapidly in the abdomen

USF Health launches nation’s first fully integrated institute for voice, hearing and swallowing care and research

Why rethinking wellness could help students and teachers thrive

Seabirds ingest large quantities of pollutants, some of which have been banned for decades

When Earth’s magnetic field took its time flipping

Americans prefer to screen for cervical cancer in-clinic vs. at home

Rice lab to help develop bioprinted kidneys as part of ARPA-H PRINT program award

Researchers discover ABCA1 protein’s role in releasing molecular brakes on solid tumor immunotherapy

[Press-News.org] Assessment of neutrophil extracellular traps in coronary thrombus of case series of patients with COVID-19