Lower testosterone during puberty increases the brain's sensitivity to it in adulthood
For men with lower levels during puberty, higher testosterone increases brain response to faces
2021-02-15
(Press-News.org) Young men with lower testosterone levels throughout puberty become more sensitive to how the hormone influences the brain's responses to faces in adulthood, according to new research published in JNeurosci.
During prenatal brain development, sex hormones like testosterone organize the brain in permanent ways. But research suggests that testosterone levels during another developmental period -- puberty -- may have long-lasting effects on brain function, too.
Liao et al. examined the relationship between puberty testosterone levels and the brain's response to faces. Liao's team recruited 500 men around age 19 who had been participants in the Avon Longitudinal Study of Parents and Children, a British birth cohort study established in 1991-1992. The longitudinal study collected blood samples at several time points throughout puberty, which the research team used to determine testosterone levels. The study participants were asked to watch videos of facial expressions while in in an fMRI scanner and provide a saliva sample on the day of the scan. For men with lowest testosterone levels during puberty, high levels of testosterone on the day of the fMRI scan were linked to greater brain activity in areas sensitive to faces. However, men with higher levels of testosterone throughout puberty did not show an increase in activity in these brain areas with high testosterone levels. These results highlight that an individual's history, not just their state on a given day, may contribute to the individual differences often seen in brain responses.
INFORMATION:
Manuscript title: Pubertal Testosterone and Brain Response To Faces in Young Adulthood: an Interplay Between Organizational and Activational Effects in Young Men
About JNeurosci
JNeurosci, the Society for Neuroscience's first journal, was launched in 1981 as a means to communicate the findings of the highest quality neuroscience research to the growing field. Today, the journal remains committed to publishing cutting-edge neuroscience that will have an immediate and lasting scientific impact, while responding to authors' changing publishing needs, representing breadth of the field and diversity in authorship.
About The Society for Neuroscience
The Society for Neuroscience is the world's largest organization of scientists and physicians devoted to understanding the brain and nervous system. The nonprofit organization, founded in 1969, now has nearly 37,000 members in more than 90 countries and over 130 chapters worldwide.
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[Press-News.org] Lower testosterone during puberty increases the brain's sensitivity to it in adulthood
For men with lower levels during puberty, higher testosterone increases brain response to faces
