COVID-19 vaccines may not produce sufficient antibody response in transplant recipients

When clinical trials were conducted to determine the immunogenicity -- the ability to elicit an immune response -- for the first two vaccines marshaled against SARS-CoV-2the virus that causes COVID-19, one group was not among those included: people who have received solid organ transplants and others (such as those with autoimmune disorders) who are immunocompromised.

Now, Johns Hopkins Medicine researchers have tried to rectify that inequity, taking one of the first looks at how people who are immunocompromised respond to their first dose of one of the two mRNA vaccines -- Moderna and Pfizer-BioNTech -- currently being administered worldwide. Their findings, as published March 15, 2021, in a research letter in the END