DNA testing before tissue diagnosis and time to treatment in lung cancer

JAMA Network Open

2023-07-25

(Press-News.org) About The Study: The use of plasma circulating tumor DNA testing before tissue diagnosis among patients with suspected advanced lung cancer may expedite biomarker testing and accelerate time to treatment.

Authors: Natasha B. Leighl, M.D., of the University Health Network in Toronto, Ontario, Canada, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi: 10.1001/jamanetworkopen.2023.25332)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.25332?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072523

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Origins of glioma brain cancer found to be in the epigenome

2023-07-25

RESEARCH SUMMARY Study Title: Modeling Epigenetic Lesions that Cause Gliomas Publication: Cell, Tuesday, July 25, 2023 (https://doi.org/10.1016/j.cell.2023.06.022) Dana-Farber Cancer Institute Authors: Gilbert J. Rahme, PhD; Nauman M. Javed, MD, PhD; Kaitlyn L. Puorro; Volker Hovestadt, PhD; Sarah E. Johnstone, MD, PhD; Bradley E. Bernstein, MD, PhD Summary: While cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at Dana-Farber and the Broad ...

Gloomy climate calculation: Scientists predict a collapse of the Atlantic ocean current to happen mid-century

2023-07-25

Gloomy climate calculation: Scientists predict a collapse of the Atlantic ocean current to happen mid-century. Important ocean currents that redistribute heat, cold and precipitation between the tropics and the northernmost parts of the Atlantic region will shut down around the year 2060 if current greenhouse gas emissions persist. This is the conclusion based on new calculations from the University of Copenhagen that contradict the latest report from the IPCC. Contrary to what we may imagine about the impact ...

CiDRE renders alveolar macrophages susceptible to SARS-CoV-2 invasion

2023-07-25

Researchers from Tokyo Medical and Dental University (TMDU) find that alveolar macrophages expressing the readthrough transcript CiDRE are stimulated by interleukin-10 to express ACE2, the SARS-CoV-2 receptor, and promote cytokine storm in patients with COVID-19 Tokyo, Japan – Despite intensive research since the pandemic began, much remains unknown about COVID-19, particularly why it can be so severe in some cases and relatively mild in others. Now, researchers from Japan have identified a genetic quirk that could make some patients more likely to experience severer ...

Robotic hand rotates objects using touch, not vision

2023-07-25

Inspired by the effortless way humans handle objects without seeing them, a team led by engineers at the University of California San Diego has developed a new approach that enables a robotic hand to rotate objects solely through touch, without relying on vision. Using their technique, the researchers built a robotic hand that can smoothly rotate a wide array of objects, from small toys, cans, and even fruits and vegetables, without bruising or squishing them. The robotic hand accomplished these tasks using only information based on touch. The work could aid in the development of robots that can manipulate objects in the ...

AI as a leader? A conversation we need to have!

2023-07-25

How can an AI become the boss? Already during the COVID-19 pandemic, we have seen how crucial digital technologies have become for leadership. Without Microsoft Teams, Zoom, and related programs, leaders would not have been able to reach their employees easily. These tools continue to enjoy a secured place in the office today. There is no surprise there. Anything that can be considered a competitive advantage will be utilized as such, and digital options are often quicker, more cost-efficient, or simply more convenient. Indeed, in the future, leadership as a whole is going to make giant leaps toward digitalization. The next phase is therefore only logical: digitally supported leadership, that ...

Mount Sinai receives significant funding to study which coronary revascularization procedure best improves survival and quality of life for women and underserved minority groups

2023-07-25

The Icahn School of Medicine at Mount Sinai will help lead and launch the first clinical trial focusing on women and minority populations to determine which coronary revascularization procedure best improves their survival and quality of life. This trial will be funded through $29.9 million from the Patient-Centered Outcomes Research Institute Award to the Icahn School of Medicine at Mount Sinai and Weill Cornell Medicine. “While there have been many trials comparing coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI), most have enrolled ...

Large PCORI award funds study of surgical options for coronary artery disease in underrepresented patient populations

2023-07-25

A multi-institutional team of scientists led by Dr. Mario Gaudino, the Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery and assistant dean for clinical trials at Weill Cornell Medicine, has been approved for a nearly $30 million funding award from the Patient-Centered Outcomes Research Institute (PCORI). The award will fund the first study among women and Black and Hispanic patients comparing the effectiveness of two revascularization options used to treat coronary artery disease. Coronary artery disease, a narrowing or blockage of coronary arteries due to plaque buildup, is the leading ...

Offsetting or reducing CO2: This is what consumers want

2023-07-25

Whether it’s recycled aluminum at Apple’s MacBook Air or compensation payments from Microsoft for emissions over the life of an Xbox, climate-friendly products are becoming more and more popular. But do consumers also pay attention to how a neutral climate balance is created? Companies use two ways to accomplish this goal: reducing emissions directly or compensating them afterward. “Both approaches can make a product climate-neutral and have a positive impact on the environment, while compensatory measures are being discussed more and more critically in the public. To this end, the consumers in our study were ...

AI uses lung CT data to predict mortality risk

2023-07-25

OAK BROOK, Ill. – Artificial intelligence (AI) can use data from low-dose CT scans of the lungs to improve risk prediction for death from lung cancer, cardiovascular disease and other causes, according to a study published in Radiology, a journal of the Radiological Society of North America (RSNA). The U.S Preventive Services Task Force recommends annual lung screening with low-dose CT (LDCT) of the chest for individuals ages 50 to 80 years with a high risk of lung cancer, such as longtime ...

Road salt pollution in many US lakes could stabilize at or below thresholds set by the EPA

2023-07-25

Since de-icing with road salt began in the 1930s, the salinity of lakes across much of the US has been steadily increasing, posing a potential threat to aquatic life and drinking water supplies. However, a cautiously optimistic new study in Limnology and Oceanography Letters concludes that if we can hold steady or decrease road salt use, levels in many lakes could stabilize below thresholds set by the US Environmental Protection Agency (EPA). “For the majority of US lakes, road salt pollution could be a solvable problem, if ...

Measurable residual disease shows strong potential as an early indicator of survival in patients with acute myeloid leukemia

Chemotherapy and radiation are comparable as pre-transplant conditioning for patients with b-acute lymphoblastic leukemia who have no measurable residual disease

DNA testing before tissue diagnosis and time to treatment in lung cancer

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: