FOR IMMEDIATE RELEASE Researchers at Johns Hopkins University School of Medicine say they have evidence from a new study in rats that spinal cord stimulation (SCS) may be useful in reducing chronic pain in people undergoing active treatment with a common anti-cancer drug. The study found that the use of SCS measurably reduced pain response in rats that were implanted with human lung cancer tissue — without compromising effectiveness of treatment with paclitaxel, a drug used to treat a variety of cancers. The study, published April 11 in Neuromodulation: Technology at the Neural ...

Norway, like other Nordic countries, widely utilised non-mandatory advice during the COVID-19 pandemic in the attempt to reduce social contacts among people and occasionally turned to obligatory measures, specifically during peaks in transmission. In comparison with stricter interventions, non-mandatory measures are usually less invasive and costly and have been recommended in previous pandemics, including influenza. Mobile phone data provides mobility metrics In their research article published in Eurosurveillance today, Kamineni et al. compare the impact on mobility when previously non-mandatory ...

WASHINGTON — New and advanced types of nuclear reactors could play an important role in helping the U.S. meet its long-term climate goals, but a range of technical, regulatory, economic, and societal challenges must first be overcome, says a new report from the National Academies of Sciences, Engineering, and Medicine. Development, testing, and widespread deployment of these reactors could take several decades. The report makes recommendations for the U.S. Department of Energy, the Nuclear Regulatory Commission, other federal and state agencies, and private industry to lay the groundwork required for advanced reactors to become a viable part of the U.S. energy system. Currently, ...

A plant-based compound purified from the traditional Chinese herb, Astragalus, has the potential to improve the outcome of heart attack patients, new research has revealed. Experts at Newcastle University, UK, have found that the product, known as TA-65®, significantly reduces inflammation and, unlike current cardiovascular treatments, does not negatively impact immunity. A study, published in GeroScience, showed that when TA-65® was given to older patients for over a year after their heart attack, it specifically increased lymphocytes, improving immunity ...

TORONTO, April 27, 2023 – Families of those with serious mental health issues feel stigmatized and alone, say York University researchers in a new study. “We are avoided. When we told our family, they shut us out, I am so hurt, and so angry” – 62-year-old mom with an adult son with serious mental illness, as described to York researchers. It’s well known that those who have serious mental illnesses such as schizophrenia face a great deal of stigma in society, but what has been less understood is the concept of “stigma by ...

The 819-day calendar used by ancient Mayans has long stumped researchers, but anthropologists from Tulane University may have finally deciphered its secrets. Researchers long suspected the calendar followed astronomical events, specifically how long it takes a planet to appear in the same place in the night sky as seen from Earth, known as the synodic periods of planets. But, according to the study published in Ancient Mesoamerica, the cycles in the Maya calendar cover a much larger timeframe than scholars previously thought. “Although prior research has sought to show planetary connections for the 819-day count, its four-part, color-directional scheme is too short to fit well with ...

Crop yield can be maximized when the best genetic variety and most effective crop management practices are used for cultivation. Scientists have developed various machine learning models to predict the factors that produce the greatest yield in specific crop plants. However, traditional models cannot accommodate high levels of variation in parameters or large data inputs. This can lead to the failure of models under certain circumstances. Also, since crop models are restricted to the types of input they can accommodate, ...

When manipulating an arcade claw, a player can plan all she wants. But once she presses the joystick button, it’s a game of wait-and-see. If the claw misses its target, she’ll have to start from scratch for another chance at a prize.  The slow and deliberate approach of the arcade claw is similar to state-of-the-art pick-and-place robots, which use high-level planners to process visual images and plan out a series of moves to grab for an object. If a gripper misses its mark, it’s back to the starting point, where the controller must map out a new plan.   Looking to give ...

Studies show that some species may require breeding in captivity within the next 200 years to avoid extinction. This reality places heavy importance on the reintroduction practices used to successfully transfer species from captivity to the wild. A new study from George Mason University looks at some of the most popular conservation techniques and identifies which have the highest likelihood of success for the reintroduction of bird species back into the wild. George Mason doctoral student Jessica Roberts and biology professor Dr. David Luther examined various conservation management methods from the past 50 years to identify the most successful ...

A new test revealed that FDA-approved antibiotics — available at your neighborhood pharmacy — can effectively treat superbugs. They are not prescribed, however, because the gold-standard test predicts they will not work. The new test may improve the way antibiotics are developed, tested and prescribed — and it is openly available to all. The research has significant implications in the fight against bacterial resistance by optimizing the prescription and use of currently available antibiotics and enhancing the efforts to discover new ones. Developed by a research team of UC Santa Barbara scientists, the antibiotic study was published in the ...

Animals tend to get smaller as their populations grow because of increased competition for food resources among members of the same species. That’s not what has happened with California sea lions, however, according to a new study led by scientists at UC Santa Cruz. Published April 27 in Current Biology, the study found that male California sea lions have gotten bigger as the population grew over the past 50 years, while female body size has remained stable. “It’s counterintuitive. You would expect that their body size would decrease as dietary resource competition intensified,” said coauthor Paul Koch, professor of Earth and planetary sciences at UCSC. The ...

In a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the organs of recently deceased patients to understand how metastatic cutaneous melanoma spreads in those who had initially benefited from precision therapies. Results are published online ahead of print in Nature Medicine. The researchers, including collaborators at the Lineberger Comprehensive Cancer Center in Chapel Hill, North Carolina, and the Vanderbilt-Ingram Cancer Center in Nashville, Tennessee, said unveiling the landscape of DNA and RNA alterations ...

A unique treatment combining radiation and immunotherapy can eradicate pancreatic tumors while stopping the cancer from spreading, according to a new study by researchers at the University of Colorado Cancer Center. The study, published today in the journal Cancer Cell, offers new hope to those with this often deadly disease. “This is the first time we’ve seen the eradication of a pancreatic tumor that suggests the cancer cell has memory, meaning we can stop the disease from coming back,” said lead author Sana Karam, MD, PhD, member of the CU ...

A study of ChatGPT found the artificial intelligence tool answered less than half of the test questions correctly from a study resource commonly used by physicians when preparing for board certification in ophthalmology. The study, published in JAMA Ophthalmology and led by St. Michael’s Hospital, a site of Unity Health Toronto, found ChatGPT correctly answered 46 per cent of questions when initially conducted in Jan. 2023. When researchers conducted the same test one month later, ChatGPT scored more than 10 per cent higher. The potential of AI in medicine and exam preparation ...

Habitats suitable for Asian elephants (Elephas maximus) across Asia have decreased by over 64% – equating to 3.3 million square kilometres of land – since the year 1700, estimates a study published in Scientific Reports. The authors suggest that habitat loss from 1700, after centuries of relative stability, coincides with the colonial-era use of land and subsequent agricultural intensification in South Asia. Asian elephants live in a range of habitats including grasslands and rainforests, but with increasing human use of land and habitat loss, elephants can come ...

Health and environmental advocates today called on communities, school boards and governments at every level to accelerate the electrification of school buses, replacing tens of thousands of diesel-powered school buses spewing toxic fumes that can seriously harm child health and interfere with learning. Led by the Canadian Partnership for Children’s Health and Environment (CPCHE), a coalition of 34 organisations made the goal of all-electric school bus fleets in Canada the central focus of this year’s national Healthy Environments for Learning Day (April 27). The joint call for urgent action by ...

About The Study: This systematic review and meta-analysis suggests a higher incidence of Bell palsy (BP) among SARS-CoV-2–vaccinated versus placebo groups. The occurrence of BP did not differ significantly between recipients of the Pfizer/BioNTech versus Oxford/AstraZeneca vaccines. SARS-CoV-2 infection posed a significantly greater risk for BP than SARS-CoV-2 vaccination.  Authors: Amir Kheradmand, M.D., of Johns Hopkins University in Baltimore, and Mehran Rahimlou, Ph.D., of the Zanjan University of Medical Sciences in Zanjan, Iran, are the corresponding authors.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoto.2023.0160) Editor’s ...

About The Study: In this study that included 125 text-based multiple-choice questions provided by the OphthoQuestions free trial for ophthalmic board certification examination preparation, ChatGPT answered approximately half of the questions correctly. Medical professionals and trainees should appreciate the advances of AI in medicine while acknowledging that ChatGPT as used in this investigation did not answer sufficient multiple-choice questions correctly for it to provide substantial assistance in preparing for board certification at this time. Authors: Rajeev H. Muni, M.D., M.Sc., of St. Michael’s Hospital/Unity Health Toronto in Toronto, is the corresponding ...

About The Study: The findings of this study suggest that ChatGPT provides postoperative instructions that are helpful for patients with a fifth-grade reading level or different health literacy levels. However, ChatGPT generated instructions scored lower in understandability, actionability, and procedure-specific content than Google Search– and institution-specific instructions.  Authors: Noel Ayoub, M.D., M.B.A., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoto.2023.0704) Editor’s ...

An international team of researchers led by Prof. MA Keping from the Institute of Botany of the Chinese Academy of Sciences (IBCAS) has shown that forests with higher tree species richness tend to have greater arthropod diversity. The researchers showed that higher tree diversity promotes productivity through the suppression of herbivores by enemy arthropods. These findings, published recently in Nature Ecology & Evolution, underscore the importance of arthropod diversity as a mediator of the effects of tree diversity ...

Researchers from Tokyo Medical and Dental University (TMDU) utilize an advanced DNA sequencing technique to reveal the factors that contributed to the death of a 5-year-old child with COVID-19 Tokyo, Japan – Sudden, unexplained child mortality is a tragedy; determining the cause of death is important for improving healthcare and providing loved ones with closure. Now, researchers from Japan have reported the use of an advanced DNA sequencing technique, whole-exome sequencing (WES), to determine why a young child died after a relatively mild infection. In a study published ...

A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of ageing at the molecular level. They found that the process of reading genetic information does not run as smoothly in older individuals as it does in younger ones. These changes in the transcription process are due to particular RNA molecules that influence the activity of individual genes and thus determine which proteins the body produces – physiological ...

New research out of the University of Cincinnati examines the association between genetics and the presence of opioid use disorder (OUD). The study identified six single nucleotide polymorphisms (SNPs) or genetic variants that are linked to OUD. The study was published in the journal Clinical Pharmacology & Therapeutics. “We are trying to identify some of the genetic variants that might play into OUD,” says Caroline Freiermuth, MD, associate professor in the Department of Emergency ...

WASHINGTON — Researchers have developed a new light-based computing scheme that uses a photonic integrated circuit to reduce the energy necessary for cryptocurrency and blockchain applications. Mining cryptocurrencies like Bitcoin—a process of verifying transactions and adding new cryptocurrency to the blockchain—consumes up to 1% of the world’s energy. This energy expenditure is expected to grow as cryptocurrency and blockchain applications become increasingly mainstream. Cryptocurrencies are digital currencies created using encryption algorithms. These alternative currencies require ...

The State Key Laboratory of Marine Pollution (SKLMP) of City University of Hong Kong (CityU) received approval from the UNESCO Intergovernmental Oceanographic Commission (IOC) Sub-Commission for the Western Pacific (WESTPAC) to establish the first UNESCO regional training and research Centre (the Coastal-COMMIT Centre, also known as the “Centre”) on coastal contaminant monitoring and marine innovative technologies in Hong Kong for the Western Pacific region. The Centre aims to strengthen the monitoring capacity for marine pollution in the Western Pacific region, promote the development of marine innovation ...