Researchers at National Jewish Health found that a subset of children suffering recurring fevers as a result of long COVID-19, benefited from a daily medication treatment commonly used for gout and periodic fever syndrome. Using the drug Colchicine, researchers saw rapid improvement not only in their fevers but also with other long COVID symptoms such as brain fog, fatigue, and achiness. The case study was just published in Journal of Allergy and Clinical Immunology, (JACI: In Practice). Long COVID is defined as persistent symptoms lasting ...

East Hanover, NJ – April 25, 2023 – New data shows that Hispanics with disabilities in the United States rebounded to historic levels in the labor force following the first 12-month period of the COVID-19 pandemic. While the disparity between their non-Hispanic white counterparts remains, their recovery has narrowed this gap and surpassed that of their black/African American counterparts, according to experts speaking during last Friday’s nTIDE Deeper Dive Lunch & Learn Webinar. To further improve employment opportunities ...

In the majority of cases, graft failure after heart transplantation is attributable to abnormalities like severe coronary artery disease. As donors with extended criteria like advanced age and pre-existing heart conditions become eligible for heart transplantation, careful screening for congenital abnormalities has become crucial. Invasive coronary angiography is an essential screening tool that can detect coronary artery disease (CAD), a condition characterized by cholesterol deposits in the heart's arteries. However, logistical challenges limit utility so it’s used for fewer than a third of donors who are at risk of developing CAD. To overcome this limitation, a new heart ...

-- JOINT PRESS RELEASE OF FORSCHUNGSZENTRUM JÜLICH AND JOHANNES GUTENBERG UNIVERSITY MAINZ -- SynDLP could be a bacterial ancestor of eukaryotic membrane proteins The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks. The cell membrane encloses the cell interior, but is constantly remodeled, for example, due to membrane budding, invagination, or fusion processes. This also involves various proteins that were long assumed to be present exclusively or predominantly in higher organisms. ...

If they exist, intermediate-mass black holes likely devour wayward stars like a messy toddler — taking a few bites and then flinging the remains across the galaxy — a new Northwestern University-led study has found. In new 3D computer simulations, astrophysicists modeled black holes of varying masses and then hurled stars (about the size of our sun) past them to see what might happen.  When a star approaches an intermediate-mass black hole, it initially gets caught in the black hole’s orbit, the researchers discovered. After that, the black hole begins its lengthy and violent meal. Every time the star makes a lap, the black hole takes a bite — ...

Dungeness crab fishermen are at high risk for on-the-job injury, but having a metal bar to bang crab pots against as they harvest can help them prevent injury, an Oregon State University study found. The study sought to determine whether the fishermen-designed “banger bar” actually improves worker safety aboard crab vessels. The metal bar is installed atop the crab-sorting table and makes it easier for fishermen to empty the crab pots they haul up from the ocean floor, but there is no industry standard on whether crabbers install one or how they ...

1. Introduction While the pathophysiology of Parkinson’s disease (PD) is not fully understood, it has been traditionally linked to a reduction in the dopamine available to brain regions involved in motor control (Alexander, 2004, Brooks, 2010, Fahn, 2008, Meder et al., 2019, Obeso et al., 2017, Poewe et al., 2017). It is important to note that much of what is known about the neural bases of motor deficits in PD is based on task-based functional magnetic resonance imaging (fMRI) studies showing abnormal motor-related blood oxygen ...

Lutz Grossmann is on a scientific mission to create tasty, animal-free protein that has a low carbon footprint and is produced without relying on agricultural land – a usual and progressively stressed source of the global food supply.  “The increasing global population and a changing climate increase the pressure on our food and protein supply coming from these natural habitats,” says Grossmann, an assistant professor of food science at the University of Massachusetts Amherst.  “By 2050, we need ...

CAMBRIDGE, MA — MIT engineers have designed a new nanoparticle sensor that could enable early diagnosis of cancer with a simple urine test. The sensors, which can detect many different cancerous proteins, could also be used to distinguish the type of a tumor or how it is responding to treatment. The nanoparticles are designed so that when they encounter a tumor, they shed short sequences of DNA that are excreted in the urine. Analyzing these DNA “barcodes” can reveal distinguishing features of a particular patient’s tumor. The researchers designed their test so that it can be performed using a strip of paper, ...

99% of the world's population breathes air that exceeds the limits recommended by the World Health Organization (WHO). This scenario is exacerbated in urban areas where more than 50% of the world's population is concentrated. To mitigate the problem of air pollution, considered by the WHO to be the main environmental risk factor for health worldwide, it is crucial to have more reliable and accurate data on the concentration of air pollutants in our cities, especially nitrogen dioxide (NO2) because of its harmful effects on ...

Humans and horses have enjoyed a strong working relationship for nearly 10,000 years — a partnership that transformed how food was produced, people were transported and even how wars were fought and won. Today, we look to horses for companionship, recreation and as teammates in competitive activities like racing, dressage and showing. Can these age-old interactions between people and their horses teach us something about building robots designed to improve our lives? Researchers with the University of Florida say yes. “There are no fundamental guiding principles ...

Doctors often use tongue depressors when peering in a patient’s mouth and throat. But what if that flat wooden spatula could actively evaluate the patient’s health? That’s the premise of an ecofriendly disposable sensor, reported in ACS’ Analytical Chemistry, that can check levels of glucose and other biomarkers in saliva. Researchers say the easy-to-produce device could someday help doctors assess a range of conditions. Wood is a renewable, biodegradable, natural material that is widely available at low cost, which makes it attractive for researchers who design electronics and sensors. However, this is challenging because the material isn’t good ...

WHAT: Children with multisystem inflammatory syndrome (MIS-C)—a rare condition linked with the virus that causes COVID-19—have biochemical indicators of cell injury and cell death that are distinct from other children with COVID-19, according to a study funded by the National Institutes of Health. Using high speed, artificial intelligence-controlled molecular sequencing of blood-and-plasma RNA and plasma DNA, researchers found that children with MIS-C have biomarkers indicating damage to multiple organs, the lining of blood vessels and the nervous system. MIS-C usually occurs two to six weeks after ...

LA JOLLA, CALIF. April 25, 2023 - With the help of a new grant from the U.S. Department of Defense for more than $1.7 million, Associate Professor Charles Spruck, Ph.D., will advance an innovative therapeutic approach for metastatic prostate cancer. Known as viral mimicry, the approach tricks the body into thinking that it has a viral infection, stimulating an immune response that can help the body fight cancer. “In viral mimicry, the body thinks there’s an infection, which kicks the ...

Effective weed control is crucial in agriculture to ensure high crop productivity. It entails the careful separation of weeds from crops before herbicides are sprayed in the fields. In simple terms, the goal of weed control is to remove the weeds while ensuring that the crop are not harmed. Traditional weed control methods have several drawbacks, such as crop contamination, herbicide waste, and poor accuracy. Therefore, it is essential to develop methods that can precisely locate and identify the boundary between a crop and weed and implement ...

Researchers have a new scientific tool called Polybot, combining the power of artificial intelligence with robotics. Potential applications include speeding up the discovery of wearable biomedical devices, materials for better batteries and more. Today’s wearable technologies like smart glasses and watches are just the start. The next generation of flexible electronics will be more efficient and sustainable, better able to monitor our health and treat certain diseases, and much more. They will be composed of electronic polymer materials — a soft pliable substance that can conduct electricity. “Just imagine the next generation of polymer ...

New York (April 25, 2022) — The American Geriatrics Society (AGS) today announced Shelley R. McDonald, DO, PhD, MCG, as 2023 Clinician of the Year. Dr. McDonald, who is an Associate Professor of Internal Medicine at Duke University School of Medicine, will be honored at the 2023 AGS Annual Scientific Meeting (#AGS23) being held in Long Beach, CA, from May 4-6 (preconference day is May 3). “Our 2023 Clinician of the year, Dr. Shelley McDonald, is a national champion for improved perioperative care of older adults undergoing surgery,” said ...

NEW YORK, April 25, 2023 ‒ Aetion®, the global leader in real-world evidence (RWE) technology and analytics, is pleased to announce the culmination of the RCT-DUPLICATE demonstration project, with complete findings published today in The Journal of the American Medical Association (JAMA). This three-year initiative tested whether researchers asking clinical questions in real-world data (RWD) — data from patients’ day-to-day interactions with the healthcare system — would obtain similar results to findings from randomized clinical trials (RCTs). In cases where clinical trial designs aligned with real patient care processes, the RWE studies and RCTs came ...

Consumption of cannabis (marijuana) or derivatives during pregnancy can cause respiratory problems for the baby, such as impaired control of breathing and diminished sensitivity to carbon dioxide, both of which favor sudden infant death syndrome. These are the main findings of a study conducted in Brazil and reported in an article published in the British Journal of Pharmacology. The authors are researchers at São Paulo State University (UNESP) and the University of São Paulo (USP). They gave pregnant rats a synthetic compound (WIN 55) that acts on the brain in a similar manner to natural cannabinoids. Harmful effects occurred mainly in male pups. “Cannabis ...

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between “test tube” data about neurons and the function of those cells in the living brain. Their study, published in the peer-reviewed journal Nature Communications, could help in the development of treatments for neurological diseases and disorders that target specific neuron types based on their roles.  “This work allows us to start looking at the brain like the complex machine that it is, rather than ...

Medical centers around the world could significantly reduce their carbon footprint and expenses by turning off MRIs and putting them in the lowest power mode instead of idling them when not in use, a new study in Radiology found. Health care is responsible for up to 4.4% of global carbon emissions, and imaging contributes an outsized share due to its energy-intensive devices, especially MRI. A 2020 study found that three CTs and four MRIs used the same amount of energy per year as a town of 852 people, for example. Though turning a machine off is better than idling, a substantial amount of MRI energy consumption occurs in “off” ...

CHAMPAIGN, Ill. — In a new study, scientists explored the links between three measures known to independently predict healthy aging: nutrient intake, brain structure and cognitive function. Their analysis adds to the evidence that these factors jointly contribute to brain health in older adults.  Reported in the Journal of Nutrition, the study found that blood markers of two saturated fatty acids, along with certain omega-6, -7 and -9 fatty acids, correlated with better scores on tests of memory and with larger brain structures in the frontal, ...

For the first time in the University of North Carolina at Charlotte’s nearly 80-year history, a faculty member has won a NASA Exobiology grant. Assistant Professor of Bioinformatics and Genomics Richard Allen White III will use the ultra-competitive grant in his research on microbialites, a kind of “living rock” that could hold the key to how life formed on Earth. Microbialites form when microbial mats, living colonies of mostly bacteria, transform into stronger hard structures. White explores how viruses may have helped to kickstart the transformation (i.e., lithification) of modern microbialites, which ...

Treating opioid addiction should be much easier now than it was a few years ago, thanks to pandemic-era rule changes that aim to improve access to buprenorphine, a medicine proven to help in recovery. But a new study shows the rate of people starting on buprenorphine remained flat from 2019 through 2022, while the percentage of patients who stayed on buprenorphine for at least six months hovered at just over 20% from 2016 through 2022. Until more health care providers start offering buprenorphine treatment -- and to take advantage of opportunities like emergency visits and hospitalizations ...

WASHINGTON, April 25, 2023 – Tsunamis are incredibly destructive waves that can destroy coastal infrastructure and cause loss of life. Early warnings for such natural disasters are difficult because the risk of a tsunami is highly dependent on the features of the underwater earthquake that triggers it. In Physics of Fluids, by AIP Publishing, researchers from the University of California, Los Angeles and Cardiff University in the U.K. developed an early warning system that combines state-of-the-art acoustic technology with artificial intelligence to immediately classify earthquakes and determine potential tsunami ...