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Short bursts of daily activity linked to reduced cancer risk

2023-07-27
Promising new research suggests a total of just 4.5 minutes of vigorous activity that makes you huff and puff during daily tasks could reduce the risk of some cancers by up to 32 percent.  Published in JAMA Oncology and led by the University of Sydney, Australia, the study used data from wearable devices to track the daily activity of over 22,000 ‘non-exercisers’. Researchers then followed the group’s clinical health records for close to seven years to monitor for cancer. As few as four to five minutes of vigorous intermittent lifestyle physical activity or ‘VILPA’ was associated with a substantially lower cancer risk compared to those who undertook no ...

Johns Hopkins Applied Physics Laboratory restores cold sensation in amputees’ phantom limbs

Johns Hopkins Applied Physics Laboratory restores cold sensation in amputees’ phantom limbs
2023-07-27
Johns Hopkins Applied Physics Laboratory (APL) researchers have developed one of the world’s smallest, most intense and fastest refrigeration devices, the wearable thin-film thermoelectric cooler (TFTEC), and teamed with neuroscientists to help amputees perceive a sense of temperature with their phantom limbs. This advancement, one of the first of its kind, enables a useful new capability for a variety of applications, including improved prostheses, haptics for new modalities in augmented reality (AR) and thermally-modulated therapeutics for applications such as pain management. The technology also has a variety ...

New resource harmonizes 16S and shotgun sequencing data for microbiome research

New resource harmonizes 16S and shotgun sequencing data for microbiome research
2023-07-27
Two leading sequencing techniques are no longer at odds, thanks to an international effort led by scientists at University of California San Diego. In a study published July 27, 2023 in Nature Biotechnology, the researchers debuted a new reference database called Greengenes2, which makes it possible to compare and combine microbiome data derived from either 16S ribosomal RNA gene amplicon (16S) or shotgun metagenomics sequencing techniques.  “This is a significant moment in microbiome research, as we’ve effectively rescued over a decade’s worth of 16S data that might have otherwise become obsolete in the modern world ...

Preventing weight gain: Yo-yo no-go zones for Australians

2023-07-27
  There’s no doubt that Aussies love a good celebration. We’re all in when it comes to the weekend, and most of us can’t go past a Christmas celebration without a little bit of overindulging. But all this comes at a cost, and it’s taking a massive toll on our waistline.   Now, a world-first study from the University of South Australia exposes the real weight gains of everyday Australians, in a move to tackle overweight and obesity.   Funded by the NHMRC, and published in JAMA Open Network today, the study explored how weight changes across a 12-month period, finding that weight fluctuated throughout the year.   Specifically, ...

Closing cancer cell’s escape route

Closing cancer cell’s escape route
2023-07-27
Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell’s genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients. NF-κB is a family of gene regulators that controls a wide variety of cellular processes – from immune responses to embryonic development – and is activated by the enzyme complex ...

Fiber-infused ink enables 3D-printed heart muscle to beat

2023-07-27
Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures. Their goals include creating better in vitro platforms for discovering new therapeutics for heart disease, the leading cause of death in the United States, responsible for about one in every five deaths nationally, and using 3D-printed cardiac tissues to evaluate which treatments might work best in individual patients. A more distant aim is to fabricate implantable tissues that can heal or replace faulty or diseased structures inside a patient’s heart. In a paper published in Nature Materials, researchers ...

New technology promises rapid and reliable development of new diagnostic tests

New technology promises rapid and reliable development of new diagnostic tests
2023-07-27
QUT researchers have developed a new approach for designing molecular ON-OFF switches based on proteins which can be used in a multitude of biotechnological, biomedical and bioengineering applications. The research team demonstrated that this novel approach allows them to design and build faster and more accurate diagnostic tests for detecting diseases, monitoring water quality and detecting environmental pollutants. Professor Kirill Alexandrov, of the QUT School of Biology and Environmental ...

Jinghui Zhang, Ph.D., elected Fellow of the International Society for Computational Biology

Jinghui Zhang, Ph.D., elected Fellow of the International Society for Computational Biology
2023-07-27
(Memphis, Tenn. – July 27, 2023) St. Jude Children’s Research Hospital proudly announces that Jinghui Zhang, Ph.D., Member of the Department of Computational Biology, has been elected as a Fellow of the International Society for Computational Biology. Zhang is one of 15 scientists given this distinction in 2023. She’s being honored for the development and application of innovative computational methods, discovering novel targets and accelerating research and genomic data sharing to advance the diagnosis, treatment and surveillance of pediatric cancers and survivors.  “I ...

Motivation and pleasure deficits play important role in social functioning across psychiatric disorders

2023-07-27
Dr. Raymond Chan's team from the Institute of Psychology of the Chinese Academy of Sciences and his collaborators have recently shown that amotivation and anhedonia, rather than expressive dysfunction, play a crucial role in determining the social functioning of schizophrenia patients. The study was published in Nature Mental Health. Negative symptoms refer to the loss of normal functioning, including anhedonia, avolition, alogia, asociality, and affective blunting, and have been shown to be the most important predictors ...

Storing fat at the waist may NOT up diabetes risk, surprise findings indicate

Storing fat at the waist may NOT up diabetes risk, surprise findings indicate
2023-07-27
Conventional wisdom holds that storing fat around your belly puts you at increased risk for type 2 diabetes. But surprising new findings from the University of Virginia School of Medicine suggest that naturally occurring variations in our genes can lead some people to store fat at the waist but also protect them from diabetes. The unexpected discovery provides a more nuanced view of the role of obesity in diabetes and related health conditions. It also could pave the way for more personalized medicine – treatments tailored to the individual. ...

Using cosmic weather to study which worlds could support life

2023-07-27
COLUMBUS, Ohio – As the next generation of giant, high-powered observatories begin to come online, a new study suggests that their instruments may offer scientists an unparalleled opportunity to discern what weather may be like on far-away exoplanets.  Dubbed the extremely large telescopes (ELTs), these observatories, which include the Extremely Large Telescope (ELT), the Giant Magellan Telescope (GMT), and the Thirty Meter Telescope (TMT), will be some of the largest ground-based telescopes ever built, and their instruments are expected to exceed ...

Introducing the 'Polyphenols Innovation Network': Catalyzing advances in polyphenols research

Introducing the Polyphenols Innovation Network: Catalyzing advances in polyphenols research
2023-07-27
Malta – We are delighted to announce the launch of the Polyphenols Innovation Network (PIN), a pioneering initiative designed to accelerate progress in the field of polyphenols research by fostering a collaborative and innovative environment. Under the banner of PIN, our mission is to assemble a diverse team of multidisciplinary experts, committed to advancing the frontiers of polyphenols research, applications, and innovation. Projects of PIN: Three pioneering projects have been earmarked for initiation under the auspices ...

Study addresses use of teleneurology to improve access to outpatient care, other inequity issues

2023-07-27
INDIANAPOLIS – Accessing neurologic care often presents physical, geographical and financial challenges to patients, many of whom face chronic and disabling conditions. With a nationwide scarcity of neurologists in the U.S., especially in rural areas, disparities in access to timely neurological assessment and treatment are not uncommon. Telehealth addresses access to care as well as other inequity issues. To meet the need for prompter care and to diminish disparity for rural veterans, the U.S. Department of Veterans’ Affairs (VA) National Teleneurology Program was funded in 2019 by the VA’s Office of Rural Health. The program is a patient-centered, ...

UV disinfection in the treatment management of SARS-CoV-2 Omicron variants

UV disinfection in the treatment management of SARS-CoV-2 Omicron variants
2023-07-27
The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its new variants has created a need for effective disinfection technologies to protect against harmful pathogens. While vaccines offer some protection, their effectiveness against future variants is uncertain. Therefore, additional strategies are important during the pre-vaccine stage. UV irradiation has lately emerged as a safe, effective, and convenient strategy to inactivate and eliminate disease-causing micro-organisms. The wavelength range of 200-235 ...

Fullerene-pillared porous graphene with high water adsorption capacity

Fullerene-pillared porous graphene with high water adsorption capacity
2023-07-27
Separation processes are essential in the purification and concentration of a target molecule during water purification, removal of pollutants, and heat pumping, accounting for 10–15% of global energy consumption. To make the separation processes more energy efficient, improvement in the design of porous materials is necessary. This could drastically reduce energy costs by about 40–70%. The primary approach to improving the separation performance is to precisely control the pore structure. In this regard, ...

Tuning surface molecular design of porous carbon for blue energy harvesting

Tuning surface molecular design of porous carbon for blue energy harvesting
2023-07-27
Did you know rivers carry about 40 trillion metric tons of river water into the ocean every year? This meeting point, known as the estuary, holds great potential for electricity generation. Mixing the two types of water -- seawater and river water containing different salt concentrations -- releases a substantial amount of Gibbs free energy, which can be converted to electricity using semipermeable membranes. However, the performance of membranes has limited the economic viability of membrane-based approaches, leaving the vast potential of this naturally abundant energy source largely untapped. To overcome the challenges associated with the membranes, researchers have developed membrane-free ...

New research reveals historic migration’s link to present-day implicit racial bias

2023-07-27
Roughly six million Black people moved away from the American South during the Great Migration between 1910 and 1970, hoping to escape racial violence and discrimination while pursuing economic and educational opportunities. Now, research has uncovered a link between this historic event with present-day inequalities and implicit biases. In a new Social Psychological and Personality Science article, researchers report that current implicit bias among White people at the county-level is associated with the proportion of Black residents living in that county during the Great Migration (circa 1930). The research supports the Bias ...

Sri Lanka floods easier to predict with India weather tool

2023-07-27
Floods and landslides in Sri Lanka could be better predicted by applying weather forecasting techniques currently used in India, a study has found. The new research has the potential to help communities better prepare for extreme rainfall in Sri Lanka. The South Asian island is extremely vulnerable to floods and landslides caused by heavy rainfall. In May 2017, more than 150 people were killed after Sri Lanka experienced flooding triggered by monsoon rains. Led by Dr Akshay Deoras and published today (Thursday, 27 July) in Geophysical Research Letters, the study expands the ...

Study highlights importance of quality and potency of saw palmetto extracts in prostate health supplements

2023-07-27
A new study published in the Journal of Urology Open Plus reveals that 7 saw palmetto products met the identity and potency standards to effectively address urinary tract symptoms associated with an enlarged prostate. According to the lead author of the study, Dr. Bilal Chughtai, who is a board-certified urologist, of the 28 supplements included in the study, only six of the lipid extracts and one multi-active product were found to have the appropriate dosage of 320 milligrams of saw palmetto extract and the minimum 80% fatty acids clinically shown to address ...

New app developed at NYU Tandon School of Engineering promises to make navigating subway stations easier for people with blindness and low vision

New app developed at NYU Tandon School of Engineering promises to make navigating subway stations easier for people with blindness and low vision
2023-07-27
A new trip-planning app has shown encouraging results in improving navigation inside subway stations, according to a study published in IEEE Journal of Translational Engineering in Health and Medicine, promising the possibility of easier commutes for people who are blind and low-vision.  Designed by researchers at NYU Tandon School of Engineering and NYU Grossman School of Medicine, Commute Booster routes public-transportation users through the “middle mile” – the part of a journey inside subway stations or other similar transit hubs – in addition to the “first” and “last” miles that bring travelers to and from those hubs.  “The ...

New research shows potential role for mangos in supporting vascular health and antioxidant activities

2023-07-27
Boston - July 27, 2023 - Mangos are one of the most popular fruits1 in the world, grown in more than 100 countries2 globally and consumed by an extremely diverse population. Now, two new studies funded by the National Mango Board and presented as posters during the American Society for Nutrition’s Annual Conference (Nutrition 2023) show mangos may play a role in risk reductions for vascular issues while helping to improve antioxidant levels among relatively healthy adult men and women who are overweight ...

James Webb Space Telescope sees Jupiter moons in a new light

James Webb Space Telescope sees Jupiter moons in a new light
2023-07-27
With its sensitive infrared cameras and high-resolution spectrometer, the James Webb Space Telescope (JWST) is revealing new secrets of Jupiter's Galilean satellites, in particular Ganymede, the largest moon, and Io, the most volcanically active. In two separate publications, astronomers who are part of JWST's Early Release Science program report the first detection of hydrogen peroxide on Ganymede and sulfurous fumes on Io, both the result of Jupiter's domineering influence. "This ...

Tiny surgical robots could transform detection and treatment of cancers

Tiny surgical robots could transform detection and treatment of cancers
2023-07-27
The ultra-soft tentacle, which measures just 2 millimetres in diameter and is controlled by magnets, can reach some of the smallest bronchial tubes and could transform the treatment of lung cancer.  It paves the way for a more accurate, tailored, and far less invasive approach to treatment and has been developed by engineers, scientists and clinicians based at the STORM Lab in Leeds.  The researchers tested the magnetic tentacle robot on the lungs of a cadaver and found that it can travel 37% deeper than the standard equipment and leads to less tissue damage.  The results ...

Fusion model hot off the wall 

Fusion model hot off the wall 
2023-07-27
Kyoto, Japan -- Humans may never be able to tame the Sun, but hydrogen plasma -- making up most of the Sun's interior -- can be confined in a magnetic field as part of fusion power generation: with a caveat.  The extremely high temperature plasmas, typically as high as 100 million degrees Celsius, confined in the tokamaks -- donut-shaped fusion reactors -- cause damage to the containment walls of these mega devices. Researchers inject hydrogen and inert gases near the device wall to cool the plasma by radiation and recombination, ...

Stockholm University leads Bio-LUSH for development of new sustainable bio-based fibers for a circular bioeconomy

2023-07-27
Bio-LUSH, a Horizon Europe project led by Stockholm University, extracts high-quality fibers from diverse plants, maximizing resource utilization for sustainable bio-based innovation. Supported by the EU-call Circular Bio-based Europe Joint Undertaking (CBE JU), the research project establishes a value chain for sustainable products such as textiles, food packaging and reinforced composites ready for the consumer market, thus driving plant-based solutions for a circular bioeconomy. The four-year Bio-LUSH project, launched in May 2023, supports the establishment of a ...
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