The younger generation of workers, although raised with and on technology, are not as technology savvy as the older generations believe. A new study by researchers in The University of Toledo John B. and Lillian E. Neff College of Business and Innovation published in the END ...

ATS 2021, New York, NY - Results from the NAVIGATOR study of tezepelumab showed that the new biologic therapy significantly reduced exacerbations requiring hospital stays and emergency department (ED) visits for adults and adolescents with severe, uncontrolled asthma, according to research presented at the ATS 2021 International Conference. NAVIGATOR (NCT03347279) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial. "Tezepelumab offers new therapeutic opportunities for patients who are currently ineligible for biologic treatments," said study author/investigator Arnaud Bourdin, MD, professor, Département de Pneumologie et Addictologie, PhyMedExp, University ...

ATS 2021, New York, NY - Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries. Dupilumab also rapidly improved lung function within two weeks, an improvement that was sustained for up to 52 weeks (the length of the trial), compared to placebo. "We hope results from the VOYAGE ...

The international community has made major progress towards the global target on protected and conserved area coverage, but has fallen far short on its commitments on the quality of these areas, according to a new report from the UN Environment Programme World Conservation Monitoring Centre (UNEP-WCMC) and the International Union for Conservation of Nature (IUCN), produced with support from the National Geographic Society. The latest edition of the biennial Protected Planet Report is the final report card on Aichi Target 11 - the global 10-year target on protected and conserved areas which aimed to bring important benefits to both biodiversity ...

ATLANTA - MAY 19, 2021 - Cancer prevention and early detection measures show mixed progress, and substantial racial/ethnic, socioeconomic, and geographic disparities continue to exist according to the recent American Cancer Society (ACS) article on cancer prevention and early detection efforts in the United States in 2018 and 2019. All data was compiled prior to the COVID-19 pandemic. This study, which appears in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, and accompanies the ACS's biennial report, Cancer Prevention & Early Detection Facts & Figures, is one of the only sources that looks at major modifiable ...

Abu Dhabi, UAE: NYU Abu Dhabi (NYUAD) researchers have developed a special noncontact multi-physics probe (NMP) that enables them to collect cytoplasmic samples from single tumor cells without disrupting their spatial configurations in the original tissue. The tiny tool can also be used to introduce foreign materials to selected cells within the tissue to alter their genetic makeup. As a result, the NMP will facilitate advanced studies that could improve the current understanding of the basic building blocks of diseases, including cancer and Alzheimers, and lead to the development of new therapies. Moreover, this could lead to a powerful tool in the field of stem cell biology and reprogramming. ...

No one expected the "Automated Guided Vehicles" at St. Olavs Hospital in Trondheim, Norway, to have personalities. These motorized units, like long boxes on wheels, are merely meant to transport garbage, medical equipment or food from one part of the hospital to another.  But because they have to interact with humans, by warning them to get out of the way, they have to talk. And that's when the fun began. Instead of using a generic Norwegian voice, they decided to give the hospital robots a voice that used the strong, distinctive local dialect. Suddenly these stainless-steel boxes, rolling around the hospital to transport goods, had a personality. They were kind of pushy. A little ...

The coronavirus pandemic has created a great demand for rapidly diagnosing SARS-CoV-2 infections. Reliable rapid tests are needed, for example, at airports and ports for testing travellers quickly and effortlessly before their journey. Researchers at the University of Helsinki have developed a new rapid assay principle for viral antigen detection, applying it to diagnosing SARS-CoV-2 infections. The test is based on a phenomenon known as time-resolved Förster resonance energy transfer (TR-FRET), where energy travels between two light-sensitive molecules when they are close enough to each other. TR-FRET makes it possible to measure viral particles or the body's own proteins by using what ...

Scientists from Tomsk Polytechnic University and Université Grenoble Alpes (France) have proposed a more accurate method for loading capability assessment of power transformers. As an example, the scientists defined the loading capability of the power transformer in Tomsk and Grenoble. The research findings are published in the International Journal of Electrical Power and Energy Systems (IF: 3,588, Q1). The cost of a power transformer can reach a few hundred million rubles that makes it the most expensive element of an electrical grid. Therefore, power engineers tend to use the loading capability of transformers in full. The method proposed by the TPU scientists can help to operate power transformers closer to their thermal limit. It will allow operators to control ...

Research has found that strict lockdowns to reduce the spread of COVID-19 might be responsible for delaying normal cardiorespiratory development in children. The study, the first to examine the topic, is published in the European Journal of Pediatrics. It was carried out by Dr Lee Smith of Anglia Ruskin University (ARU) and a team of academics from Spain, led by Dr Ruben Lopez-Bueno of the University of Zaragoza. The research involved a group of 89 children from a school in north-eastern Spain. The country introduced a strict six-week lockdown in spring 2020, during which under-15s were unable to leave their homes except for medical ...

World-leading eye experts have made a breakthrough that could potentially change the way cataracts are treated - with potential for drug therapy to replace surgery. Cataract is a clouding of the eye lens that develops over time and affects the quality of vision. It is caused by an accumulation of protein in the lens that reduce the transmission of light to the retina. Previous research led by ARU found that cataracts account for almost half of global cases of blindness. A significantly developed cataract can only currently be treated by a surgical procedure to remove the cloudy lens and insert an artificial replacement. A team of international scientists, ...

Due to the extensive clearing of their habitat, these primates sometimes turn to palm oil monocultures while foraging. This often leads to conflicts with farmers. The macaques do not damage the palm oil fruits to any great extent. On the contrary, they can even benefit palm oil cultivation, as they are excellent hunters of the masses of rats found on plantations, the main pest found there. As a new study has now been able to prove, however, regularly visiting the plantations has a significant impact on macaques' social behaviour. This was shown by researchers from the Max Planck Institute for Evolutionary Anthropology (MPI-EVA), Leipzig University (UL), Universiti Sains Malaysia (USM) and the German Centre for Integrative Biodiversity Research (iDiv). The new findings ...

Active music-making can provide cognitive benefits to older adults with mild cognitive impairment or dementia, according to an analysis of all relevant studies. The analysis, which is published in the Journal of the American Geriatrics Society, also found that music may help improve their quality of life and mood. The analysis included nine studies with a total of 495 participants. The authors noted that music-based interventions could potentially provide millions of older adults with critical support for their cognitive, emotional, and social well-being. "We are excited to see these results because participating in music, like singing in a choir or playing ...

Brazil is the world leader in sweet orange production, but citrus cultivation in the region faces constant threats concerning the availability of water and the outbreak of diseases. New research published in the Journal of Applied Microbiology indicates that a fatty acid called hexanoic acid may help protect against one such problem: citrus canker, a bacterial infection that causes brownish eruptive lesions on the leaves, stems, and fruit of citrus trees. Hexanoic acid might be a suitable substitute for chemicals used to protect citrus from bacterial infections. Investigators examined several ...

Little is known concerning environmental contaminants in predators at the top of a food chain. A study published in Environmental Toxicology and Chemistry has demonstrated that new types of brominated flame retardants accumulate in the tissues of killer whales near Norway and are also passed on to nursing offspring. Investigators also detected man-made chemicals called perfluoroalkyl substances (PFAS) in the tissues of adult killer whales. Thresholds for health effects of PFAS in marine mammals are not established, but the chemical has been linked to reproductive and endocrine effects in wildlife. In addition, polychlorinated biphenyls (PCBs), which have long been banned, were detected in the blubber of 7 of the 8 killer whales in the study at levels that exceeded the ...

Skoltech researchers and their colleagues from China and Germany have presented a new search algorithm for single-atom-alloy catalysts (SAACs) that found more than 200 yet unreported candidates. Their work provides a recipe for finding best SAACs for various applications. The paper was published in the journal END ...

Scientists have successfully treated flies displaying behavioural problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics. Schizophrenia is a severe long-term mental health condition that is historically poorly understood and treated. It is relatively common, affecting one to two per cent of the population, and is known to be up to 80 per cent genetic in origin. Recent advances in sequencing genomes of people with schizophrenia have identified a list of novel genes and mutations associated with the disease. Many ...

NEW YORK, NY (May 19, 2021)--A new study from Columbia University and an international team of researchers identifies multiple ways to achieve the same health benefits from exercise--as long as the exercise "cocktail" includes plenty of light physical activity. "For decades, we've been telling people that the way to stay healthy is to get at least 30 minutes of exercise five days a week," says Keith Diaz, PhD, assistant professor of behavioral medicine and director of the exercise testing laboratory at the Center for Behavioral Cardiovascular Health at Columbia University Vagelos College of Physicians and Surgeons. "But even if you're one of the few adults who can stick to this advice, 30 minutes represents ...

The work was conducted under the auspices of the Russian Science Foundation; the project "Synthesis and research of a new class of nanocomposite ceramics with degenerate dielectric constant for optoplasmonic applications" is headed by Professor Sergey Kharintsev (KFU's Institute of Physics). Professor Kharintsev, the first co-author, comments, "Under the influence of light, collective oscillations of electrons can be excited in metallic nanostructures, and as a result the electric field in the vicinity of the nanostructures strongly increases. The field of physics that studies the effects of generation and propagation of such electromagnetic excitations is ...

Computed tomography -- CT scanning -- which combines a series of X-ray images taken from different angles around an organism and uses computer processing to create cross-sectional images of its bones, is providing new insight into an old initiative to characterize fishes in Africa's Lake Malawi. The process, demonstrated in a new study using the high-resolution X-ray computer system in Penn State's Center for Quantitative X-Ray Imaging, is important because it will lead to the identification and management of more of the fish species in Africa's second largest lake, according to lead researcher Jay Stauffer Jr., distinguished professor of ichthyology in the College of Agricultural Sciences. "Before they can effectively ...

"I think you're on mute." This was the most-used phrase of 2020, according to Human Resources Online. Emblazoned on T-shirts and embossed on coffee-mugs, we used the meme to make fun of ourselves while learning video-conferencing tools like Zoom and Microsoft's Teams. But for the more than 7 million Americans who suffer from vocal disorders, not being heard is a serious matter. Many people who have normal speaking skills have great difficulty communicating when their voice box, the larynx, fails. This can occur if the vocal cords, the two bands of smooth muscle tissue in the larynx, suffer damage from an accident, surgical procedure, viral infection or cancer. There is no replacement for the ...

SARS-CoV-2 has evolved to acquire mutations on the spike protein--the part of the virus that protrudes from its surface and latches onto cells to infect them--that enhance the coronavirus' ability to bind to human cells or evade antibodies. A new study from the Centers for Genomics and Systems Biology at New York University and NYU Abu Dhabi uses computational modeling to assess the biological significance of spike protein mutations, uncovering versions of the virus that bind more tightly or resist antibodies and offering a promising public health surveillance tool. The study, which appears in the Journal of Molecular Biology, also suggests that these mutations on the spike protein are a key ...

Press release - ESE statement: COVID-19 and endocrine and metabolic diseases. An updated statement from the European Society of Endocrinology New expert statement confirms strong links between our hormones and COVID-19 The endocrine system is strongly involved in SARS-Cov-2 infection - so much so that evidence of an "endocrine phenotype" of COVID-19 has emerged, according to a statement by the European Society of Endocrinology (ESE) published in the journal Endocrine in April 2021. Leading endocrinology researchers looked into the evidence that has accumulated over the past year since the pandemic emerged, and consistently found evidence ...

PROVIDENCE, R.I. [Brown University] -- The field of mathematical topology is often described in terms of donuts and pretzels. To most of us, the two differ in the way they taste or in their compatibility with morning coffee. But to a topologist, the only difference between the two is that one has a single hole and the other has three. There's no way to stretch or contort a donut to make it look like a pretzel -- at least not without ripping it or pasting different parts together, both of which are verboten in topology. The different number of holes make two shapes that are fundamentally, inexorably different. In recent years, researchers have drawn on mathematical topology to help explain a range of phenomena like phase transitions in matter, aspects of Earth's climate and even how zebrafish ...

One-quarter to one-third of young, active patients who undergo anterior cruciate ligament reconstruction experience a second ACL injury after they return to sport (RTS). New research indicates that young athletes who feel confident about their knee health at the time of medical clearance for sports participation after ACL surgery have a higher likelihood of meeting all RTS criteria related to physical function but also have a higher likelihood of experiencing a second ACL injury within 2 years after RTS. The study, which included 159 participants with an average age of 17 years, is published in the Journal of Orthopaedic Research. "These data suggest that as health care providers, we may need to re-evaluate the tools we currently use to determine readiness to return ...