Conventional silicon-based computing, which has advanced by leaps and bounds in recent decades, is pushing against its practical limits. DNA computing could help take the digital era to the next level. Scientists are now reporting progress toward that goal with the development of a novel DNA-based GPS. They describe their advance in ACS' The Journal of Physical Chemistry B. Jian-Jun Shu and colleagues note that Moore's law, which marked its 50th anniversary in April, posited that the number of transistors on a computer chip would double every year. This doubling has ...

COLUMBUS, Ohio - A new study has identified a regulatory pathway in natural killer cells that inhibits their maturation and homing behavior. Natural killer cells are one of the body's first lines of defense against viruses and cancer. The findings could lead to new strategies for boosting natural-killer cell activity against cancer and viral infections. The study was led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James). It showed that a protein called Foxo1 ...

WASHINGTON, DC, May 6, 2015 -- Some 9 million American families lost their homes to foreclosure during the late 2000s housing bust, driving many to economic ruin and in search of new residences. Hardest hit were black, Latino, and racially integrated neighborhoods, according to a new Cornell University analysis of the crisis. Led by demographer Matthew Hall, researchers estimate racial segregation grew between Latinos and whites by nearly 50 percent and between blacks and whites by about 20 percent as whites abandoned and minorities moved into areas most heavily distressed ...

The justices of the nation's highest court are weighing whether the Environmental Protection Agency should have considered potential compliance costs before proceeding with a rule that requires power plants to reduce their mercury emissions. In March, lawyers from the government and industry presented their sides to the Supreme Court, which could decide the matter in June, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society. Glenn Hess, a senior correspondent at C&EN, notes that the EPA developed the ...

Water, when cooled below 32°F, eventually freezes -- it's science known even to pre-schoolers. But some substances, when they undergo a process called "rapid-freezing" or "supercooling," remain in liquid form -- even at below-freezing temperatures. The supercooling phenomenon has been studied for its possible applications in a wide spectrum of fields. A new Tel Aviv University study published in Scientific Reports is the first to break down the rules governing the complex process of crystallization through rapid-cooling. According to the research, membranes can be ...

The Ebola virus (EBOV) causes lethal hemorrhagic fever in humans, with extremely high morbidity and mortality. It was first discovered in two simultaneous outbreaks near the Ebola River in sub-Saharan Africa in 1976. Sporadic outbreaks followed until 2014, when it re-emerged in Western Africa and caused a widespread epidemic. As of 24 April 2015, the World Health Organization (WHO) has reported a total number of 26,101 suspected cases and 10,824 deaths. Despite the high death rate of the Ebola hemorrhagic disease, there are no FDA-approved treatments or vaccines available ...

Scientists at the University of Chicago, Harvard, and China have described the surprising discovery and function of a new DNA modification in insects, worms, and algae. Common DNA modifications occur through methylation, a chemical process that can dramatically change gene expression, which regulates the eventual production of proteins that carry out the functions of an organism. It's all part of a growing new subfield of epigenetics being pioneered by the University of Chicago's Chuan He and his collaborators. Through epigenetics, organisms sometimes bypass the genetic ...

UNIVERSITY OF CALIFORNIA, BERKELEY'S HAAS SCHOOL OF BUSINESS--Not everyone may care about having an impressive job title or a big, fancy house but all human beings desire a high level of social status, according to a newly published study. For decades, researchers have argued both sides of the question: is it human nature to want high standing in one's social circle, profession, or society in general? Prof. Cameron Anderson sought to settle the debate. In "Is the desire for status a fundamental human motive? A review of the empirical literature" (Psychological Bulletin, ...

Ludwig Maximilians Universitaet (LMU) in Munich physicists at the Laboratory for Attosecond Physics have developed a new laser-light source that will lead to significant advances in research on fundamental physics. The future of electronics lies in optical control of electron flows. That would enable data processing operations to be performed at frequencies equivalent to the rate of oscillation of visible light - some 100,000 times faster than is feasible with current techniques. Physicists at the Laboratory for Attosecond Physics (LAP), which is run jointly by LMU Munich ...

Tomosynthesis detects 40% more breast cancers than traditional mammography does, according to a major screening study from Lund University, Sweden. This is the first large-scale study to compare the screening method with regular mammograms. The 3D X-ray technique is also more comfortable for women, as breast compression is halved. A total of 7 500 women aged 40-74 took part in the first half of the study, which formed the basis for the findings. "We see a change as inevitable. Breast tomosynthesis will be introduced, it is just a question of when and on what scale," ...

A new system dynamic model makes it possible to plan the profitability of mining operations with greater precision than before. Researchers in business at Lappeenranta University of Technology, LUT have developed a model based on system thinking that supports investment decision-making by mining companies and helps optimise the guidance of production in mining investments. The model that has been built has already sparked interest among international mining companies. "The planning of international investments with the help of more detailed models can save tens of millions ...

VTT has developed a sensor that detects ethanol in the headspace of a food package. Ethanol is formed as a result of food spoilage. The sensor signal is wirelessly readable, for instance, by a mobile phone. VTT Technical Research Centre of Finland Ltd is searching for a partner so as to commercialise the sensor. The sensor monitors ethanol emitted from the spoilage of foods into the headspace of a package. Ethanol, in addition to carbon dioxide, was found to be the main volatile spoilage metabolite in fresh-cut fruit. The information given by the sensor is transmitted ...

This news release is available in German. On 11 March 2011, a massive release of stress between two overlapping tectonic plates occurred beneath the ocean floor off the coast of Japan, triggering a giant tsunami. The Tohoku quake resulted in the death of more than 15,000 people, the partial or total destruction of nearly 400,000 buildings, and major damage to the Fukushima nuclear power plant. This "superquake" may have been the largest in a series of earthquakes, thus marking the end of what's known as a supercycle: a sequence of several large earthquakes. A research ...

The study, published today in the journal Critical Care Medicine and carried out at Royal Brompton Hospital, followed children undergoing surgery for congenital heart disease, and found that by analysing metabolites in the blood -- molecules created as a result of metabolism -- it was possible to predict a child's clinical outcome. Congenital heart disease is relatively common, affecting between 4 and 14 babies in every 1,000 live births. Around one third of affected children require surgery during early childhood. However, surgery itself can cause complications, affecting ...

University of Adelaide researchers have discovered a target for the development of completely new antibiotics against disease-causing bacteria. Published online ahead of print in the leading microbiology journal Molecular Microbiology, the researchers have identified a building block common to many types of bacterial 'virulence factors' (the bacterial proteins which act as weapons to cause disease, such as toxins or degrading enzymes). The building block, called the Passenger-associated Transport Repeat (PATR), has been found in virulence factors of many major harmful ...

Recognizing that patients' experiences of childhood and adult trauma are common and have a direct impact on their health, UCSF clinical researchers and Positive Women's Network-USA have developed and are reporting a new primary care model. "In our clinic where we treat women with HIV, we are able to deliver lifesaving anti-HIV medications, but we still lose patients far too often. Looking back over the last ten years, only 16 percent of our patient deaths were due to HIV/AIDS. Most deaths were due to events such as depression, suicide, murder, drug overdoses and lung ...

Scientists at the University of Copenhagen have identified one mechanism that explains how some stem cells choose to become a given cell type: the cells combine specific sets of proteins at precise positions along the DNA. When these particular groups of proteins are combined, the gates are opened so that certain groups of genes can now be used, giving the cells a new identity. Scientists have now identified one of these combinations, which drive the cells along the path that allow them to become organs such as liver and pancreas. This latest research could lead scientists ...

About one-quarter of adults aged 65 years and older used mobility devices--such as canes, walkers, and wheelchairs--in 2011, and about a third of these reported using multiple devices. The use of such devices was not linked with an increased risk of falling, but people who used canes were more likely to report limiting their activities because they worried about falling. The findings indicate that the percentage of older adults using mobility devices has increased in recent years, and the use of multiple devices is common. "Staying active is a key component to staying ...

It sounds like something out of a horror movie: a penis-shaped worm which was able to turn its mouth inside out and drag itself around by its tooth-lined throat, which resembled a cheese grater. But a new study of the rather unfortunately-named penis worm has found that their bizarre dental structure may help in the identification of previously unrecognised fossil specimens from the time on Earth when animals were first coming into their own. Reconstructing the teeth of penis worms, or priapulids, in fine detail has enabled researchers from the University of Cambridge ...

CHICAGO -- When managers create a culture where employees know the boss puts employees' needs over his or her own, measureable improvements in customer satisfaction, higher job performance by employees, and lower turnover are the result, according to research by Robert Liden, Sandy Wayne, Chenwei Liao, and Jeremy Meuser, that has just been published in the Academy of Management Journal. Employees feel the most valued, and in return give back to the company and its customers when their bosses create a culture of trust, caring, cooperation, fairness and empathy. According ...

1986 was the least diverse year in the charts The musical revolution said to have been driven by The Beatles and The Rolling Stones was already underway before they arrived in the US. The rise of hip-hop caused the single most radical change in the US charts The researchers studied trends in style, the diversity of the charts, and the timing of musical revolutions. They find that, contrary to popular belief, the so-called "British Invasion" of US pop music by groups such as The Beatles and The Rolling Stones, did not start a rock revolution, but only followed existing ...

A new study has found high levels of infection with hepatitis C (HCV) across Africa, particularly in people infected with HIV. In the largest study of its kind to date, researchers from Imperial College London and Médecins Sans Frontières/Doctors Without Borders (MSF) collated data on over 1.1 million individuals from 213 studies to provide policymakers with robust estimates of the burden of HCV infection. The report, published in The Lancet Infectious Diseases, found that around three per cent of people in sub-Saharan Africa have been infected with HCV ...

Private practice directly affects the quality of care that NHS patients receive and doctors should not be allowed to work "on both sides of the divide", writes a senior doctor in The BMJ this week. John Dean, a consultant cardiologist at Royal Devon and Exeter NHS Foundation Trust Hospital, describes how he quit private practice after realising "it has direct adverse effects on the NHS." To begin with, he says he felt that he needed the money "to renovate the house, educate the children, and so on." And he was sure that he could keep the private work separate from the ...

WASHINGTON, D.C. - Ethanol fuel refineries could be releasing much larger amounts of some ozone-forming compounds into the atmosphere than current assessments suggest, according to a new study that found emissions of these chemicals at a major ethanol fuel refinery are many times higher than government estimates. New airborne measurements downwind from an ethanol fuel refinery in Decatur, Illinois, show that ethanol emissions are 30 times higher than government estimates. The measurements also show emissions of all volatile organic compounds (VOCs), which include ethanol, ...

URBANA, Ill. - While consumer demand for edamame or vegetable soybean remains on the rise in the United States, it's not widely grown in this country. Nearly 85 million acres of grain-type soybean were grown in the U.S. in 2014, yet edamame imported from Asia appears to dominate what we eat in this country, said a University of Illinois crop scientist. There have been limitations to growing edamame in the U.S. Midwest, including little research on the cultivars that could be used here and how to grow the crop sustainably, explained Marty Williams, who is also an ecologist ...