The needs of millions of overlooked, 'left behind' adolescent women must become a more significant priority within international efforts to end poverty by 2030, a UK Government-commissioned report is urging. The University of Cambridge report, which was commissioned by the Foreign, Commonwealth and Development Office, argues that there is an urgent need to do more to support marginalised, adolescent women in low and middle-income countries; many of whom leave education early and then face an ongoing struggle to build secure livelihoods. Amid extensive evidence which highlights the difficulties these women face, it estimates that almost a third of adolescent ...

One third (35%) of people who took a new drug for treating obesity lost more than one-fifth (greater than or equal to 20%) of their total body weight, according to a major global study involving UCL researchers. The findings from the large-scale international trial, published today in the New England Journal for Medicine, are being hailed as a "gamechanger" for improving the health of people with obesity and could play a major part in helping the UK to reduce the impact of diseases, such as COVID-19. The drug, semaglutide, works by hijacking the body's own appetite regulating system in the brain leading to reduced hunger and calorie intake. Rachel Batterham, Professor of Obesity, Diabetes and Endocrinology ...

MUSC Hollings Cancer Center researchers found that a single strain of bacteria may be able to reduce the severity of graft-versus-host disease (GVHD), as reported online in February 2021 in JCI Insight. Bone marrow transplant can be a lifesaving procedure for patients with blood cancers. However, GVHD is a potentially fatal side effect of transplantation, and it has limited treatment options. This proof-of-concept study demonstrates that better treatment options may be on the horizon for patients with GVHD. Xue-Zhong Yu, M.D., associate director of Basic Science at Hollings Cancer Center, and lead ...

Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority populations. The early analysis, part of a large-scale program funded by the National Heart, Lung, and Blood Institute, examines one of the largest and most diverse data sets of high-quality whole genome sequencing, which makes up a person's DNA. It provides new genetic insights into heart, lung, blood and sleep disorders and how these conditions impact people with diverse racial and ...

A team, including an astronomer from the University of Hawai?i Institute for Astronomy (IfA), have confirmed a planetoid that is almost four times farther from the Sun than Pluto, making it the most distant object ever observed in our solar system. The planetoid, nicknamed "Farfarout," was first detected in 2018, and the team has now collected enough observations to pin down the orbit. The Minor Planet Center has now given it the official designation of 2018 AG37. Farfarout's name distinguished it from the previous record holder "Farout," found by the same team of astronomers in 2018. The team includes UH Mānoa's David Tholen, Scott S. Sheppard of ...

The United States spends more than $200 billion every year in efforts to treat and manage mental health. The onset of the coronavirus pandemic has only deepened the chasm for those experiencing symptoms of depression or anxiety. This breach has also widened, affecting more people. New research from Carnegie Mellon University, University of Pittsburgh and University of California, San Diego found that 61% of surveyed university students were at risk of clinical depression, a value twice the rate prior to the pandemic. This rise in depression came alongside dramatic shifts in lifestyle habits. The study documents dramatic changes in physical activity, sleep and time use at the onset ...

UNIVERSITY PARK, Pa. -- The descriptions on the fronts of infant and toddler food packages may not accurately reflect the actual ingredient amounts, according to new research. The team found that vegetables in the U.S. Department of Agriculture's "dark green" category were very likely to appear in the product name, but their average order in the ingredient list was close to fourth. In contrast, juice and juice concentrates that came earlier on the ingredient list were less likely to appear in product names. "Early experiences with food can mold children's preferences and contribute to building healthful, or unhealthful, eating habits that last a lifetime," said author Alyssa Bakke, staff sensory scientist, Penn State. "Our previous work found combining ...

New Rochelle, NY, February 10, 2021--It may be safe for COVID-infected mothers to maintain contact with their babies. Keeping them apart can cause maternal distress and have a negative effect on exclusive breastfeeding later in infancy, according to The COVID Mothers Study published in the peer-reviewed journal Breastfeeding Medicine. Click here to read the article now. In this worldwide study, infants who did not directly breastfeed, experience skin-to-skin care, or who did not room-in within arms' reach of their mothers were less likely to be exclusively breastfed in the first 3 months of life. Nearly 60% of ...

Oil and water may not mix, but adding the right nanoparticles to the recipe can convert these two immiscible fluids into an exotic gel with uses ranging from batteries to water filters to tint-changing smart windows. A new approach to creating this unusual class of soft materials could carry them out of the laboratory and into the marketplace. Scientists at the National Institute of Standards and Technology (NIST) and the University of Delaware have found what appears to be a better way to create these gels, which have been an area of intense research focus for more than a decade. ...

SAN ANTONIO -- Humans possess a formidable multi-layered defense system that protects us against viral infections. Better understanding of these defenses and the tricks that viruses use to evade them could open novel avenues for treating viral infections and possibly other diseases. For example, a human protein called SAMHD1 impedes replication of the human immunodeficiency virus (HIV) and other viruses by depleting deoxynucleotides ­­-- building blocks needed for the replication of the viral genome. It has long remained a mystery whether and how this protein is activated in response to infection. Now researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have discovered that SAMHD1 recognizes a unique molecular ...

Sawfish have disappeared from half of the world's coastal waters and the distinctive shark-like rays face complete extinction due to overfishing, according to END ...

EAST LANSING, Mich. - The 1918 influenza pandemic provides a cautionary tale for what the future may hold for COVID-19, says a Michigan State University researcher. After a decade studying a flu virus that killed approximately 15,000 Michigan residents, Siddharth Chandra, a professor in MSU's James Madison College, saw his research come to life as he watched the spread of the COVID-19 pandemic. "It was so surreal," said Chandra, who has a courtesy appointment in epidemiology and biostatistics. "All of a sudden, I was living my research." Chandra's research is published in the American Journal of Public Health with co-authors Julia Christensen, a graduate of James Madison College; Madhur Chandra, Senior ...

A team of astronomers, including associate professor Chad Trujillo of Northern Arizona University's Department of Astronomy and Planetary Science, have confirmed a planetoid that is almost four times farther from the Sun than Pluto, making it the most distant object ever observed in our solar system. The planetoid, which has been nicknamed "Farfarout," was first detected in 2018, and the team has now collected enough observations to pin down its orbit. The Minor Planet Center has now given it the official designation of 2018 AG37. Farfarout's nickname distinguished it from the previous record holder "Farout," found by the same team of astronomers ...

Orange, Calif. - The mutually beneficial relationship between legumes and rhizobia, the nitrogen-fixing soil bacteria that make their home in legume root nodules and create nutrient-rich fertilizer for them, is one of the most well-known and agronomically important examples of symbiosis. New research from END ...

Individual choices in medicine carry a certain amount of uncertainty. An innovative partnership at The University of Texas at Austin takes aim at medicine down to the individual level by applying state-of-the-art computation to medical care. "Medicine in its essence is decision-making under uncertainty, decisions about tests and treatments," said Radek Bukowski, MD, PhD, professor and associate chair of Investigation and Discovery in the Department of Women's Health at Dell Medical School at UT Austin. "The human body and the healthcare system are complex systems made of ...

Firefighters and emergency medical services workers are at high risk of exposure to COVID-19 while on the job and pose an additional risk of transmitting the virus to others. Although vaccines are a promising public health tool for reducing COVID-19 transmission, little has been known about the perceptions of the COVID-19 vaccine among first responders. To provide insight, a University of Miami Miller School of Medicine-led study queried a national sample of U.S. firefighters and emergency medical services workers through an anonymous online survey. The study results, published online Feb. 1 in the Journal of Occupational ...

Ten years ago, researchers at Aarhus University, Denmark, reported the discovery of centimeter-long cable bacteria, that live by conducting an electric current from one end to the other. Now the researchers document that a few cells operate with extremely high oxygen consumption while the rest of the cells process food and grow without oxygen. An outstanding way of life. We humans need food and oxygen to live. Now, imagine if oxygen was to be found only at the mountain top and food only in the valley. That's how the world looks like for cable bacteria, which live in the bottom of seas and lakes. For them, ...

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research. Now, experts at Cincinnati Children's report success at averting drug resistance in a subtype of brain tumors called glioblastomas. Importantly, the research indicates that the approach may also work in other cancers, such as melanoma, that exhibit a similar pathway of drug resistance. The method involves inhibiting a protein called SCD and reducing the ...

A potent ozone-depleting chemical whose emissions unexpectedly spiked in recent years has quickly dropped back to much lower levels, putting the recovery of the stratospheric ozone layer back on track, according to a new study by scientists at MIT, the University of Bristol, and other institutions in South Korea, the U.S., Japan, Australia, and Switzerland. The chemical in question is CFC-11, a chlorofluorocarbon that was once commonly used for refrigeration, insulation, and other purposes. When emitted to the atmosphere, CFC-11 can loft into the stratosphere, where the sun's ultraviolet radiation breaks the chemical down to release chlorine -- a noxious chemical that then eats ...

In the face of a changing climate and crop diseases, manufacturers of products containing natural flavors and fragrances are pivoting to a new way to source ingredients. Companies have been partnering with biotechnology firms to manufacture scents and flavors using fermented microbes, which experts say are more sustainable. A new story in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, details how the industry is brewing up new fragrances. Although the availability of natural fragrances and flavors like citrus and vanilla is dwindling, the demand for them has increased, writes Senior Business Editor Melody Bomgardner. In recent years, flavor and fragrance companies have been working with the biotech industry to shore ...

Rates of overweight and obesity in children are rising around the world, with serious long-term consequences for health and health care costs. In prior research, video and mobile games have helped children eat healthier and exercise more. A new study examined how Indian 10- and 11-year-olds' food choices were affected by playing a pediatric dietary mobile game that uses implicit learning--educating players without making them aware of the lessons through innovations in neurocognitive training and immersive technology. The study found that the game significantly improved children's food choices immediately after play. The study was conducted by researchers at Carnegie Mellon University (CMU), Hofstra University, Johns Hopkins University Center for Communication Programs (CCP), ...

The visibility of scientific articles and conference papers is conditional upon being easily found in academic search engines, especially Google Scholar. To enhance this visibility, search engine optimization (SEO) has been applied in recent years to academic search engines in order to optimize documents and, thereby, ensure they are better ranked in search pages (i.e., academic search engine optimization or ASEO). Recent research, published in Future Internet, has found out whether the language of the document is a factor involved in the sorting algorithm of search results on Google Scholar. The study authors are Cristòfol Rovira, Lluís Codina and ...

Because of their small size, some microorganisms can come through the pores of bacterial filters. Such filtrable microorganisms are difficult to grow in lab conditions and therefore remain understudied. Scientists believe that filtrable microorganisms are widely spread in the biosphere and participate in many biogeochemical processes, such as the restoration of sulfur in deep-see regions. They also play an important role in the production and use of dissolved organic matter. This term refers to a group of compounds (such as amino acids, organic acids and monomeric sugars) that are easily utilizable sources of nutrients in freshwater systems. These compounds occur in pristine lotic systems at very low concentrations mainly from primary producers ...

FRANKFURT. The lens of the human eye gets its transparency and refractive power from the fact that certain proteins are densely packed in its cells. These are mainly crystallines. If this dense packing cannot be maintained, for example due to hereditary changes in the crystallines, the result is lens opacities, known as cataracts, which are the most common cause of vision loss worldwide. In order for crystallins to be packed tightly in lens fibre cells, they must be folded stably and correctly. Protein folding already begins during the biosynthesis of proteins in the ribosomes, which are large protein complexes. Ribosomes ...

Seismic monitoring devices linked to the internet are vulnerable to cyberattacks that could disrupt data collection and processing, say researchers who have probed the devices for weak points. Common security issues such as non-encrypted data, insecure protocols, and poor user authentication mechanisms are among the biggest culprits that leave seismological networks open to security breaches, Michael Samios of the National Observatory of Athens and colleagues write in a new study published in Seismological Research Letters. Modern seismic stations are now implemented as an Internet-of-Things (IoT) station, with physical devices that connect and exchange data with other devices and systems over the Internet. In their test attacks ...