PHILADELPHIA -- Women diagnosed with breast cancer are often told not to eat soyfoods or soy-based supplements because they can interfere with anti-estrogen treatment. But new research being presented at the American Association for Cancer Research (AACR) Annual Meeting 2015 could eventually impact that advice, because in animals, a long history of eating soyfoods boosts the immune response against breast tumors, reducing cancer recurrence. The study, conducted at Georgetown Lombardi Comprehensive Cancer Center, could offer good news to some women whose diet has long ...

PHILADELPHIA, April 19, 2015 - Broccoli sprout extract protects against oral cancer in mice and proved tolerable in a small group of healthy human volunteers, the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter, announced today at the American Association for Cancer Research (AACR) Annual Meeting in Philadelphia. The promising results will be further explored in a human clinical trial, which will recruit participants at high risk for head and neck cancer recurrence later this year. This research is funded through Pitt's Specialized Program ...

PHILADEPHIA, April 19, 2015 - Identifying molecular changes that occur in tissue after chemotherapy could be crucial in advancing treatments for ovarian cancer, according to research from Magee-Womens Research Institute and Foundation (MWRIF) and the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter, presented today at the American Association for Cancer Research (AACR) Annual Meeting 2015. For years now, intraperitoneal chemotherapy, a treatment which involves filling the abdominal cavity with chemotherapy drugs after surgery, has been ...

PHILADELPHIA -Genetically modified versions of patients' own immune cells successfully traveled to tumors they were designed to attack in an early-stage trial for mesothelioma and pancreatic and ovarian cancers at the Perelman School of Medicine at the University of Pennsylvania. The data adds to a growing body of research showing the promise of CAR T cell technology. The interim results will be presented at the American Association for Cancer Research (AACR) Annual Meeting 2015, April 18-22. "The goal of this phase I trial was to study the safety and feasibility of ...

Using mobile apps in preschool classrooms may help improve early literacy skills and boost school readiness for low-income children, according to research by NYU's Steinhardt School of Culture, Education, and Human Development. "Guided use of an educational app may be a source of motivation and engagement for children in their early years," said Susan B. Neuman, professor of childhood and literacy education at NYU Steinhardt and the study's author. "The purpose of our study was to examine if a motivating app could accelerate children's learning, which it did." Neuman ...

Schools must track the academic progress of homeless students with as much care as they track special education, Title I and English language learner students, according to researchers at University of the Pacific. "In an age of accountability, schools focus their efforts and attention on the students they are mandated to report on," said Ronald Hallett, associate professor of education and lead author of the study. "We need to realign our policies and procedures if we are going to improve academic outcomes for homeless and highly mobile students." Hallett and his colleagues ...

Meaningful college experiences, including internships and studying abroad, may not matter as much as your major and what school you attend when it comes to job satisfaction and earnings, according to research by NYU's Steinhardt School of Culture, Education, and Human Development. "Our study adds important nuance to our understanding of the influence specific college experiences have on economic and attitudinal job outcomes in the years following college graduation," said Gregory Wolniak, director of the Center for Research on Higher Education Outcomes at NYU Steinhardt ...

PHILADELPHIA --Poorer outcomes for African-American women with estrogen-receptor positive (ER+) breast cancer, compared with European-American patients, appears to be due, in part, to a strong survival mechanism within the cancer cells, according to a study being presented at the American Association for Cancer Research (AACR) Annual Meeting 2015. Georgetown Lombardi Comprehensive Cancer Center investigators report that breast tumors from African-American patients show reduced sensitivity to tamoxifen, a leading treatment for ER+ breast cancer, caused by increased activation ...

Chapel Hill, N.C., April 17, 2015 - Achelios Therapeutics will announce results from a Phase IIa placebo-controlled clinical trial in moderate and severe migraine sufferers treated with TOPOFEN (TM), the company's proprietary topical anti-migraine therapy. The data to be presented demonstrate that the simple application of a well-known non-steroidal anti-inflammatory drug (NSAID), using the company's proprietary formulation on the skin, over the trigeminal nerve branches, can be a safe and effective alternative treatment for patients suffering from acute migraine. William ...

Study shows there are six different types of obese people Treating individuals according to which 'type' could be more effective Targeted strategies would also mean a more efficient use of NHS services One size does not fit all when it comes to tackling obesity, according to a new study by the University of Sheffield. Researchers looking at how to tackle the country's obesity issue - which costs the NHS £6billion pounds every year* - found that currently individuals are often treated the same regardless of how healthy they are, where they live or their ...

A new paper by a team of researchers led by Karel Matous, College of Engineering Associate Professor of Computational Mechanics in the Department of Aerospace and Mechanical Engineering at the University of Notre Dame, describes how an accurate statistical description of heterogeneous particulate materials, which is used within statistical micromechanics theories, governs the overall thermo-mechanical properties. This detailed statistical description was computed using a novel adaptive interpolation/integration scheme on the nation's largest parallel supercomputers. Quantifying ...

According to the World Health Organization's 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection. Although the impact of malaria is still significant, the statistics reflect a considerable reduction in the global malaria burden. Since 2010, disease transmission has been reduced by 30 percent and mortality due to malaria has decreased by almost half. Artemisinins are powerful drugs that have the most rapid action of all current drugs against Plasmodium falciparum, the parasite ...

For decades, frustrated parents and teachers have barked at fidgety children with ADHD to "Sit still and concentrate!" But new research shows that if you want ADHD kids to learn, you have to let them squirm. The foot-tapping, leg-swinging and chair-scooting movements of children with attention-deficit/hyperactivity disorder are actually vital to how they remember information and work out complex cognitive tasks, according to a study published in an early online release of the Journal of Abnormal Child Psychology. The findings show the longtime prevailing methods for ...

April 17, 2015 - A multicenter team of U.S. and Venezuelan scientists, led by researchers from NYU Langone Medical Center, have discovered the most diverse collection of bodily bacteria yet in humans among an isolated tribe of Yanomami Indians in the remote Amazonian jungles of southern Venezuela. By comparison, the microbiome of people living in industrialized countries is about 40 percent less diverse, the scientists estimate. The team reports its findings today in the journal Science Advances. The results, the researchers say, suggest a link between modern antibiotics ...

Research by scientists at The University of Manchester has revealed that the colour of light has a major impact on how the brain clock measures time of day and on how the animals' physiology and behavior adjust accordingly. The study, for the first time, provides a neuronal mechanism for how our internal clock can measure changes in light colour that accompany dawn and dusk. In research publishing on April 17th in the Open Access journal PLOS Biology, the researchers looked at the change in light around dawn and dusk to analyze whether colour could be used to determine ...

Scientists from the Icahn School of Medicine, collaborating with a multicenter team of U.S. and Venezuelan researchers, have discovered the most diverse collection of bacteria yet in humans among an isolated tribe of Yanomami Amerindians in the remote Amazonian jungles of Venezuela. Bacterial diversity in the Yanomami, previously unexposed to antibiotics or industrialized diets, was found to be nearly double that of people living in industrialized countries, and was also significantly higher than in other remote populations moderately exposed to modern practices. The team ...

An annual report from Tel Aviv University researchers reveals that anti-Semitic incidents rose dramatically worldwide in 2014, with violent attacks on Jews ranging from armed assaults to vandalism against synagogues, schools, and cemeteries. The report, released on April 15 by TAU's Kantor Center for the Study of Contemporary European Jewry, recorded 766 incidents, mostly in Western Europe, compared to 554 in 2013 -- a surge of nearly 40 percent. The report called 2014 the worst year for anti-Semitic attacks since 2009. The authors of the report characterized such attacks ...

Researchers at the University of California, San Diego School of Medicine have created an in vitro, live-cell artificial vessel that can be used to study both the application and effects of devices used to extract life-threatening blood clots in the brain. The artificial vessel could have significant implications for future development of endovascular technologies, including reducing the need for animal models to test new devices or approaches. The findings are published in the current online issue of the journal Stroke. Cerebrovascular disease covers a group of dysfunctions ...

Early indicators of the malaria parasite in Africa developing resistance to the most effective drug available have been confirmed, according to new research published in Antimicrobial Agents and Chemotherapy. Researchers at the London School of Hygiene & Tropical Medicine found Plasmodium falciparum malaria parasites with a mutation to the gene Ap2mu were less sensitive to the antimalarial drug artemisinin. A study in 2013, also led by the School, suggested an initial link between a mutation in the ap2mu gene and low levels of malaria parasites remaining in the blood ...

COLUMBUS, Ohio - Previous research published by researchers at The Ohio State University Wexner Medical Center and three other institutions showed that when children with attention-deficit/hyperactivity disorder (ADHD) and serious physical aggression were prescribed both a stimulant and an antipsychotic drug, along with teaching parents behavior management techniques, they had a reduction of aggressive and serious disruptive behavior. Now, L. Eugene Arnold and Michael Aman, professors emeritus at the Nisonger Center at Ohio State's Wexner Medical Center, and their colleagues ...

RICHMOND, Va. (April 17, 2015) -- In a recent study, Virginia Commonwealth University School of Medicine researchers predicted which cirrhosis patients would suffer inflammations and require hospitalization by analyzing their saliva, revealing a new target for research into a disease that accounts for more than 30,000 deaths in the United States each year. The findings could trigger a change in the way researchers study chronic liver disease and associated microbiota, the network of tiny organisms in the human body such as bacteria and fungi that can either bolster an ...

This news release is available in German. Bonn, April 16 /Tokyo, April 17, 2015 - An international team of researchers at German Center for Neurodegenerative Diseases (DZNE) and Tokyo Institute of Technology (Tokyo Tech) have revealed in a collaborative study - published today in NEURON, that neurons in the eye change on the molecular level when they are exposed to prolonged light. The researchers could identify that a feedback signalling mechanism is responsible for these changes. The innate neuronal property might be utilized to protect neurons from degeneration ...

By combining two highly innovative experimental techniques, scientists at the University of Illinois at Urbana-Champaign have for the first time simultaneously observed the structure and the correlated function of specific proteins critical in the repair of DNA, providing definitive answers to some highly debated questions, and opening up new avenues of inquiry and exciting new possibilities for biological engineering. Scientists who study biological systems at the molecular level have over the years looked to the structure of protein molecules--how the atoms are organized--to ...

In anticipation of the forthcoming 2015 White House Conference on Aging (WHCoA), The Gerontological Society of America (GSA) has produced a special issue of The Gerontologist that outlines a vision for older adults' economic and retirement security, health, caregiving, and social well-being for the next decade and beyond. And because this year also marks the 50th anniversary of Medicare, Medicaid, and the Older Americans Act, as well as the 80th anniversary of Social Security, articles within the issue also explore ways to safeguard the continuing success of these programs. The ...

CAMBRIDGE, MA -- Many years of research have shown that for students from lower-income families, standardized test scores and other measures of academic success tend to lag behind those of wealthier students. A new study led by researchers at MIT and Harvard University offers another dimension to this so-called "achievement gap": After imaging the brains of high- and low-income students, they found that the higher-income students had thicker brain cortex in areas associated with visual perception and knowledge accumulation. Furthermore, these differences also correlated ...