DALLAS - March 10, 2021 - UT Southwestern scientists have identified key genes involved in brain waves that are pivotal for encoding memories. The END ...

Bacteria employ many different strategies to regulate gene expression in response to fluctuating, often stressful, conditions in their environments. One type of regulation involves non-coding RNA molecules called small RNAs (sRNAs), which are found in all domains of life. A new study led by researchers at the University of Illinois describes, for the first time, the impacts of sRNA interactions in individual bacterial cells. Their findings are reported in the journal Nature Communications, with the paper selected as an Editors' highlight article. Bacterial sRNAs are often involved in regulating stress responses using mechanisms that involve base-pairing ...

While neurological complications of COVID-19 in children are rare, in contrast to adults, an international expert review of positive neuroimaging findings in children with acute and post-infectious COVID-19 found that the most common abnormalities resembled immune-mediated patterns of disease involving the brain, spine, and nerves. Strokes, which are more commonly reported in adults with COVID-19, were much less frequently encountered in children. The study of 38 children, published in the journal Lancet, was the largest to date of central nervous system imaging manifestations of COVID-19 in children. "Thanks to a major international collaboration, we found that neuroimaging manifestations ...

When we recall a memory, we retrieve specific details about it: where, when, with whom. But we often also experience a vivid feeling of remembering the event, sometimes almost reliving it. Memory researchers call these processes objective and subjective memory, respectively. A new study from the Center for Mind and Brain at the University of California, Davis, shows that objective and subjective memory can function independently, involve different parts of the brain, and that people base their decisions on subjective memory -- how they feel about a memory -- more than on its accuracy. "The study distinguishes between ...

Aspirin is an established, safe, and low-cost medication in long-standing common use in prevention and treatment of cardiovascular diseases, and in the past a pain relief and fever reducing medication. The use of aspirin was very popular during the 1918 Spanish Influenza pandemic, several decades before in-vitro confirmation of its activity against RNA viruses. Studies showed that aspirin, in addition to its well-known anti-inflammatory effects, could modulate the innate and adaptive immune responses helping the human immune system battle some viral infections. With this information ...

Computer engineers at the world's largest companies and universities are using machines to scan through tomes of written material. The goal? Teach these machines the gift of language. Do that, some even claim, and computers will be able to mimic the human brain. But this impressive compute capability comes with real costs, including perpetuating racism and causing significant environmental damage, according to a new paper, "On the Dangers of Stochastic Parrots: Can Language Models Be Too Big? ?" The paper is being presented Wednesday, March 10 at the ACM Conference on Fairness, Accountability and Transparency (ACM FAccT). This is the first exhaustive review of the literature surrounding the risks that come with rapid growth of language-learning technologies, said ...

Effective, specific, with a reversible and non-harmful action: the identikit of the perfect biomaterial seems to correspond to graphene flakes, the subject of a new study carried out by SISSA - International School for Advanced Studies of Trieste, Catalan Institute of Nanoscience and Nanotechnology (ICN2) of Barcelona and the National Graphene Institute of the University of Manchester, in the framework of the European Graphene Flagship project. This nanomaterial has demonstrated the ability to interact with the functions of the nervous system in vertebrates in a very specific manner, interrupting the building up of a pathological process that leads ...

Healthcare personnel who were infected with COVID-19 had stronger risk factors outside the workplace than in their hospital or healthcare setting. That is the finding of a new study published today in JAMA Network Open conducted by University of Maryland School of Medicine (UMSOM) researchers, colleagues at the Centers for Disease Control and Prevention (CDC) and three other universities. The study examined survey data from nearly 25,000 healthcare providers in Baltimore, Atlanta, and Chicago including at University of Maryland Medical System (UMMS) hospitals. They found that having a known exposure to someone who tested positive for COVID-19 in the community was the strongest risk factor for testing ...

An international team led by Artem R. Oganov, a Professor at Skoltech and MISIS, and Dr. Ivan Troyan from the Institute of Crystallography of RAS performed theoretical and experimental research on a new high-temperature superconductor, yttrium hydride (YH6). Their findings were published in the journal Advanced Materials. Yttrium hydrides rank among the three highest-temperature superconductors known to date. The leader among the three is a material with an unknown S-C-H composition and superconductivity at 288 K, which is followed by lanthanum hydride, LaH10, superconducting at temperatures up to 259 K), and, finally, yttrium hydrides, YH6 and YH9, with maximum superconductivity temperatures of 224 K and 243 K, respectively. The superconductivity of YH6 ...

Boston - A new study shows that providing a non-acute care space after hospital discharge for patients with COVID-19 who are experiencing homelessness helped reduce hospitalizations and keep inpatient beds available for those requiring acute care. Published in JAMA Network Open and led by researchers at Boston Medical Center's (BMC) Grayken Center for Addiction, the study demonstrates the importance of developing innovative approaches to tackle issues facing people experiencing homelessness, including their inability to isolate, in order to mitigate additional ...

Associations between strong predictors of suicidal behaviors over the life course, such as adverse childhood events (ACEs), remain understudied among youth of color. Although not previously considered high risk, suicide attempts among Black youth increased 73% between 1991 and 2017. Published in the Children and Youth Services Review, University of Minnesota researchers pulled data from the 2016 Minnesota Student Survey (MSS) to examine associations between ACEs, school connectedness and suicide ideation and attempts among Somali, Latino, Hmong and Non-Hispanic ...

Research published in Environmental Toxicology and Chemistry shows that the presence of polybrominated diphenyl ethers (PBDEs) in bald eagle populations is slowly declining. Bald eagles are apex predators that nest and, more importantly, feed along water bodies, making them excellent bioindicators of environmental contaminants that bioaccumulate up the aquatic food web. The findings are both good news for eagles and instructive for regulators tasked with managing surface water quality by setting protective levels for wildlife, as well as fish consumption advisories for humans. Lead author Bill Route from the National ...

Scientists at Tokyo Institute of Technology (Tokyo Tech) have uncovered mechanisms underlying the activation of the MRN complex-- the cell's DNA scissors. Using purified yeast proteins, they demonstrated that phosphorylation of Ctp1, a homolog of a tumor-suppressor protein, plays a key role in activating MRN complex's DNA clipping activity. Intriguingly, a short segment of yeast Ctp1 or its human counterpart could stimulate endonuclease activity of their respective MRN complexes, suggesting its conserved function across species. DNA functions as a roadmap that guides the identity and functions of cells. A glitch in the DNA ...

BINGHAMTON, NY -- Star employees often get most of the credit when things go right, but also shoulder most of the blame when things go wrong, according to new research from Binghamton University, State University of New York. The study explored the potential risks and rewards of collaborating with stars - individuals who have a reputation for exhibiting exceptional performance - and how individual performance factors into how much credit and blame is shared with collaborators. "Stars are human, and they fail from time to time. We wanted to shift the focus away from stars, and find out what happens to the people who collaborate ...

ALBUQUERQUE, N.M. -- Geoscientists at Sandia National Laboratories used 3D-printed rocks and an advanced, large-scale computer model of past earthquakes to understand and prevent earthquakes triggered by energy exploration. Injecting water underground after unconventional oil and gas extraction, commonly known as fracking, geothermal energy stimulation and carbon dioxide sequestration all can trigger earthquakes. Of course, energy companies do their due diligence to check for faults -- breaks in the earth's upper crust that are prone to earthquakes -- but sometimes ...

Eye contact is a key to establishing a connection, and teachers use it often to encourage participation. But can a robot do this too? Can it draw a response simply by making "eye" contact, even with people who are less inclined to speak up. A recent study suggests that it can. Researchers at KTH Royal Institute of Technology published results of experiments in which robots led a Swedish word game with individuals whose proficiency in the Nordic language was varied. They found that by redirecting its gaze to less proficient players, a robot can elicit involvement from even the most reluctant participants. Researchers Sarah Gillet and Ronald Cumbal say the results offer evidence that robots could play a productive role in educational settings. Calling on someone by name isn't ...

The protein α-synuclein is one of the most abundant proteins in the human brain. It is often referred to as the "Parkinson protein", as deposition of this protein in brain cells is a hallmark of Parkinson's disease. Despite the high interest of biomedical research in the protein, many questions concerning the function and physiology of α-synuclein in living cells still remain to be answered. For example, it was previously unclear whether and to what extent the protein binds to and interacts with internal cell components such as membranes. As such processes could play a role in the development of the disease, the team led by Konstanz-based physical chemist Professor Malte Drescher used the further development of an established measurement method called ...

An article published by the researchers of the Biodiversity Unit at the University of Turku, Finland, highlights how amateur venom-extraction business is threatening scorpion species. Sustainably produced scorpion venoms are important, for example, in the pharmacological industry. However, in the recent years, there has been a dramatic increase in the number of people involved in the trade and vast numbers of scorpions are harvested from nature. This development is endangering the future of several scorpion species in a number of areas. Scorpions have existed on Earth for over 430 million years. Currently comprising over 2,500 extant species, scorpions occur on almost all the major landmasses in a range of habitats from ...

Gravity is the weakest of all known forces in nature - and yet it is most strongly present in our everyday lives. Every ball we throw, every coin we drop - all objects are attracted by the Earth's gravity. In a vacuum, all objects near the Earth's surface fall with the same acceleration: their velocity increases by about 9.8 m/s every second. The strength of gravity is determined by the mass of the Earth and the distance from the center. On the Moon, which is about 80 times lighter and almost 4 times smaller than the Earth, all objects fall 6 times slower. And on a planet of the size of a ladybug? ...

A new study published Tuesday 10 March, No Smoking Day, from King's College London highlights the 'clear benefit' of using e-cigarettes daily in order to quit smoking, and supports their effectiveness when compared to other methods of quitting, including nicotine replacement therapy or medication. Although the number of people in England who smoke has continued to fall in recent years, tobacco smoking is still the leading preventable cause of premature death and disease - killing nearly 75,000 people in England in 2019. While e-cigarettes have been around for more than a decade, evidence on their effectiveness for helping people to ...

There's a surprising amount of information stored in the hardened plaque, or calculus, between teeth. And if that calculus belongs to the remains of a person who lived in ancient times, the information could reveal new insights about the past. But the tiny samples can be difficult to work with. Now, in ACS' Journal of Proteome Research, scientists apply a new method to this analysis, finding more proteins than traditional approaches. The human mouth is full of interesting molecules: DNA and enzymes in saliva, proteins and lipids from bits of food stuck between teeth, the bacterial ...

Amsterdam, NL, March 10, 2021 - Music-based interventions have become a core ingredient of effective neurorehabilitation in the past 20 years thanks to the growing body of knowledge. In this END ...

People are different. New technology is good for patients and the healthcare system. But it could also expand the already significant health disparities in Norway and other countries. "Women and men with higher education in Norway live five to six years longer than people with that only have lower secondary school education," says Emil Øversveen, a postdoctoral fellow at the Norwegian University of Science and Technology's (NTNU) Department of Sociology and Political Science. He is affiliated with CHAIN, the Centre for Global Health Inequalities Research. The centre works to reduce social health ...

In the dry air and soil of Texas' Southern High Plains, improving soil health can be tough. We usually think of healthy soil as moist and loose with lots of organic matter. But this can be hard to achieve in this arid area of Texas. Lindsey Slaughter, a member of the Soil Science Society of America, set out with her fellow researchers to test a solution that kills two birds with one stone. They put excess cow manure on these soils to see if they could make them healthier. The team recently published their research in the Soil Science Society of America Journal. "We know that planting perennial grasslands for cattle production can help protect and restore soil in semi-arid lands that are likely to erode and degrade from intense ...

The per-capita rates of new COVID-19 cases and COVID-19 deaths were higher in states with Democrat governors in the first months of the pandemic last year, but became much higher in states with Republican governors by mid-summer and through 2020, possibly reflecting COVID-19 policy differences between GOP- and Democrat-led states, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Medical University of South Carolina. For their study, the researchers analyzed data on SARS-CoV-2-positive nasal swab tests, COVID-19 diagnoses, and COVID-19 ...