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Penn study finds living kidney donation does not increase risk of death or heart disease for older

2014-07-09
PHILADELPHIA – Previous studies linking older age with kidney and heart disease have raised concerns about the safety of living kidney donation among older adults. However, in the first study to look closely at this issue, researchers at the Perelman School of Medicine at the University of Pennsylvania report that older kidney donors (55 years and above) enjoy similar life expectancy and cardiovascular health as very healthy older people who did not donate their kidneys. In light of the ever increasing organ transplant waitlists, the authors of the study hope the results ...

Projecting a 3-dimensional future

2014-07-09
Since the 1960s, theatergoers have shelled out for crude 3-D glasses, polarized glasses, and shutter glasses to enhance their viewing experience. These basic devices, used to trick the brain into perceiving an artificial three-dimensional reality, may soon be rendered obsolete with the introduction of new holography technology developed by Tel Aviv University researchers. TAU doctoral students Yuval Yifat, Michal Eitan, and Zeev Iluz have developed highly efficient holography based on nanoantennas that could be used for security as well as medical and recreational purposes. ...

Shark teeth analysis provides detailed new look at Arctic climate change

Shark teeth analysis provides detailed new look at Arctic climate change
2014-07-09
A new study shows that some shark species may be able to cope with the rising salinity of Arctic waters that may come with rising temperatures. The Arctic today is best known for its tundra and polar bear population, but it wasn't always like that. Roughly 53 to 38 million years ago during what is known as the Eocene epoch, the Arctic was more similar to a huge temperate forest with brackish water, home to a variety of animal life, including ancestors of tapirs, hippo-like creatures, crocodiles and giant tortoises. Much of what is known about the region during this period ...

Making a more healthful, low-fat hot dog without giving up texture

2014-07-09
With grilling season upon us, many backyard cooks are turning to more healthful alternatives to their savored but fatty hot dogs. But low fat can sometimes mean low satisfaction. Now researchers are reporting new progress toward addressing the texture problem in low-fat wieners that are made with olive oil rather than pork fat. Their study was published in ACS' Journal of Agricultural and Food Chemistry. Ana M. Herrero and colleagues note that hot-dog consumers have come to expect just the right amount of chewiness and springiness, among other things, from their beloved ...

Tiny DNA pyramids enter bacteria easily -- and deliver a deadly payload

2014-07-09
Bacterial infections usually announce themselves with pain and fever but often can be defeated with antibiotics — and then there are those that are sneaky and hard to beat. Now, scientists have built a new weapon against such pathogens in the form of tiny DNA pyramids. Published in the journal ACS Applied Materials & Interfaces, their study found the nanopyramids can flag bacteria and kill more of them than medicine alone. David Leong, Jianping Xie and colleagues note that some infectious pathogens can lie in wait, undetectable in the human body or in places that antibiotics ...

My brother's keeper

2014-07-09
This news release is available in French. Montreal, July 9, 2014 — Whether it's how to throw a ball or put together a puzzle, young children learn a lot from their older siblings. While researchers have long known that brothers and sisters teach each other about the world, most of their observations about this have been made in a lab setting. A new study recently published in the Journal of Cognition and Development by Concordia University education professor Nina Howe takes that investigation a step further by observing how children interact in their natural habitat: ...

What drives a child to abuse alcohol?

2014-07-09
This news release is available in French. By looking at 40 different factors in 14 year old teens, including brain structure and function, personality, life experiences and genetics, researchers can predict with 70% accuracy who will go on to develop binge drinking within the next two years. Impulsivity, hopelessness, sensation-seeking traits, lack of conscientiousness, and other variables such as life events and a family history of drug use contribute to the likelihood of binge drinking. Whether or not the child had had a single drink at age 14 was a particularly ...

One secret of ancient amber revealed

2014-07-09
The warm beauty of amber was captivating and mysterious enough to inspire myths in ancient times, and even today, some of its secrets remain locked inside the fossilized tree resin. But for the first time, scientists have now solved at least one of its puzzles that had perplexed them for decades. Their report on a key aspect of the gemstone's architecture appears in the ACS journal Analytical Chemistry. Jennifer Poulin and Kate Helwig of the Canadian Conservation Institute point out that much of the amber we see today had its origins millions of years ago, when it exuded ...

Sunshine vitamin ups bowel cancer survival odds, study finds

2014-07-09
Bowel cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a study shows. Patients with the highest levels of vitamin D have half the risk of dying compared with those with the lowest levels, the findings reveal. The study is the first to correlate total blood levels of vitamin D in bowel cancer patients after their diagnosis – which includes that produced after exposure to sunlight and that obtained from dietary sources – with their long term survival prospects. The University of Edinburgh team tested blood samples ...

Short circuit in the food web

Short circuit in the food web
2014-07-09
Jena (Germany) They are amongst the most numerous inhabitants of the sea: tiny haptophytes of the type Emiliania huxleyi. Not visible to the naked eye, when they are in bloom in spring, they form square kilometer sized patches, they are even visible on satellite images. "Together with other phytoplankton, Emiliania huxleyi is responsible for approximately half of the global photosynthesis output," states Prof. Dr. Georg Pohnert of the Friedrich Schiller University Jena (Germany). In the process the greenhouse gas carbon dioxide – CO2 – is extracted from the atmosphere and ...

Fit for the frontline? New study identifies the hearing requirements of British soldiers

2014-07-09
AUDIO: The gunshot is a binaural recording using KEMAR, the weapon was an SA80 assault rifle and the microphone is 50m downrange from the firer and approximately 30cm from the bullet... Click here for more information. University of Southampton researchers, with assistance from the Ministry of Defence, have conducted the first study to identify the hearing requirements of British soldiers fighting on the frontline. The study, which provides an important and novel insight into ...

Even geckos can lose their grip

Even geckos can lose their grip
2014-07-09
Not even geckos and spiders can sit upside down forever. Nanophysics makes sure of that. Mechanics researchers at Linköping University have demonstrated this in an article just published in Physical Review E. Knowledge that can be of great industrial benefit. Geckos and spiders that seem to be able to sit still forever, and walk around upside down have fascinated researchers worldwide for many years. We will soon be able to buy smart new fasteners that hold the same way as the gecko's foot. But the fact is, sooner or later the grip is lost, no matter how little force ...

Frogs have developed rapid defences against the red swamp crayfish

Frogs have developed rapid defences against the red swamp crayfish
2014-07-09
The common frog is one of the amphibians with the highest distribution in the Iberian Peninsula. It reproduces preferably in permanent areas of water where it comes into contact with the red swamp crayfish, which preys on its larvae. Research carried out by the Spaniard Germán Orizaola from the University of Uppsala (Sweden) confirms that the larvae of these frogs have developed a defensive response to the invasive species. They also have deeper tails and larger bodies if they co-exist with the crayfish. Numerous invasive organisms are currently spreading outside of their ...

RUB chemists develop novel catalyst with 2 functions

2014-07-09
Chemists at the Ruhr-Universität Bochum have made a decisive step towards more cost-efficient regenerative fuel cells and rechargeable metal-air batteries. They developed a new type of catalyst on the basis of carbon, which can facilitate two opposite reactions: electrolysis of water and combustion of hydrogen with oxygen. A catalyst of this kind might make the storage of wind and solar energy and the manufacture of cost-efficient batteries, for example for electric cars, possible. The team published their report in the "International Edition" of the magazine "Angewandte ...

Rotten egg gas holds key to healthcare therapies

2014-07-09
It may smell of flatulence and have a reputation for being highly toxic, but when used in the right tiny dosage, hydrogen sulfide is now being being found to offer potential health benefits in a range of issues, from diabetes to stroke, heart attacks and dementia. A new compound (AP39), designed and made at the University of Exeter, could hold the key to future therapies, by targeting delivery of very small amounts of the substance to the right (or key) places inside cells. Scientists in Exeter have already found that the compound protects mitochondria – the "powerhouse" ...

NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection

NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection
2014-07-09
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched an early-stage clinical trial of CRS3123, an investigational oral antibiotic intended to treat Clostridium difficile (C. difficile) infection. CRS3123 (previously known as REP3123) is a narrow-spectrum agent that inhibits C. difficile growth while sparing normal intestinal bacteria. The Phase I trial will enroll up to 30 healthy men and women ages 18 to 45 in a dose-escalation study to evaluate the investigational drug's safety and tolerability. Quintiles, ...

The impact of big data on health care: Health Affairs' July issue

2014-07-09
Big data can yield big savings, if they are used in the right ways. David W. Bates of the Brigham and Women's Hospital and coauthors analyzed six use cases with strong opportunities for cost savings—high-cost patients; readmissions; triage; decompensation (when a patient's condition worsens); adverse events; and treatment optimization when a disease affects multiple organ systems. They suspect that cost-savings benefits will vary widely, though the current costs associated with all six scenarios will be significant. The authors suggest that using analytics for multiple ...

Discovery of new drug targets for memory impairment in Alzheimer's disease

Discovery of new drug targets for memory impairment in Alzheimers disease
2014-07-09
VIDEO: This is a movie showing how the reactive astrocytes in the brains of Alzheimer's disease model produce the inhibitory transmitter GABA by the enzyme MAO-B and release GABA through the... Click here for more information. Alzheimer's disease, which is the most common cause of dementia, is fatal and currently, there is no cure. In Alzheimer's disease, brain cells are damaged and destroyed, leading to devastating memory loss. It is reported that 1 in 8 Americans aged 65 or over ...

Neuroprotective effects of low concentration of lithium

2014-07-09
Lithium, as a neuroprotective agent, benefits for neuronal survival. Recent cDNA array studies have demonstrated that mood stabilizer lithium exhibits neuroprotective effects through multiple targets. Dr. Riadh Nciri and his team, Purpan Medicine Faculty, Paul Sabatier University, France, exposed SH-SY5Y cells to 0.5 mmol/L lithium carbonate for 25-50 weeks and then detected the expression levels of some neurobiology related genes and post-translational modifications of stress proteins in SH-SY5Y cells. cDNA arrays showed that pyruvate kinase 2 (PKM2) and calmodulin 3 expression ...

Filiform needle acupuncture versus antidepressant drugs for poststroke depression

2014-07-09
Whether acupuncture or antidepressant drugs exhibit better therapeutic effects on poststroke depression remains disputed. The effectiveness of acupuncture for poststroke depression can be evaluated by evidence-based medicine studies, which provide evidence for clinical application. Systematic review or meta-analysis studies have demonstrated that early acupuncture is superior to conventional western medicine in the treatment of poststroke depression. However, high-quality literatures are needed to further validate the effectiveness of acupuncture for poststroke depression. ...

What aggravates hippocampal neuronal injury in acute cerebral ischemia?

What aggravates hippocampal neuronal injury in acute cerebral ischemia?
2014-07-09
Activation of extracellular signal-regulated kinase 1/2 has been demonstrated in acute cerebral ischemia. Yaning Zhao and her colleagues, Hebei United University, China induced transient whole-brain ischemia by four-vessel occlusion in normal and diabetic rats and intravenously injected diabetic rats with extracellular signal-regulated kinase 1/2 30 minutes before ischemia as a pretreatment. Results showed that during the pathological progression of cerebral ischemia/reperfusion in rats, activation of extracellular signal-regulated kinase 1/2 exhibits protective effect ...

Depression in AMD patients with low vision can be halved by integrated therapies

2014-07-09
SAN FRANCISCO – July 9, 2014 – The first clinical trial to examine integrated low vision and mental health treatment has shown that the approach can reduce the incidence of depression by half among people with low vision due to age-related macular degeneration (AMD). The results of the study were published online today in Ophthalmology, the journal of the American Academy of Ophthalmology. Low vision is a visual impairment that interferes with a person's ability to perform everyday tasks and cannot be corrected with glasses, contact lenses, medicine or surgery. A common ...

Rehabilitation helps prevent depression from age-related vision loss

Rehabilitation helps prevent depression from age-related vision loss
2014-07-09
Depression is a common risk for people who have lost their vision from age-related macular degeneration (AMD), but a new study shows that a type of rehabilitation therapy can cut this risk in half. The study was funded by the National Eye Institute (NEI), part of the National Institutes of Health. "Our results emphasize the high risk of depression from AMD, and the benefits of multi-disciplinary treatment that bridges primary eye care, psychiatry, psychology, and rehabilitation," said Barry Rovner, M.D., a professor of psychiatry and neurology at the Sidney Kimmel Medical ...

Researchers led by Stanford engineer figure out how to make more efficient fuel cells

Researchers led by Stanford engineer figure out how to make more efficient fuel cells
2014-07-09
Solar power and other sources of renewable energy can help combat global warming but they have a drawback: they don't produce energy as predictably as plants powered by oil, coal or natural gas. Solar panels only produce electricity when the sun is shining, and wind turbines are only productive when the wind is brisk. Ideally, alternative energy sources would be complemented with massive systems to store and dispense power – think batteries on steroids. Reversible fuel cells have been envisioned as one such storage solution. Fuel cells use oxygen and hydrogen as fuel ...

Children on dairy farms less likely to develop allergies

2014-07-09
The occurrence of allergic diseases has risen dramatically in Western societies. One frequently cited reason is that children are less exposed to microorganisms and have fewer infections than previous generations, thereby delaying maturation of the immune system. A study by researchers at Sahlgrenska Academy, University of Gothenburg, monitored children until the age of three to examine maturation of the immune system in relation to allergic disease. All of the children lived in rural areas of the Västra Götaland Region, half of them on farms that produced milk. Lower ...
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