New clues from the dawn of the solar system
2015-03-16
A research group in the UA Lunar and Planetary Laboratory has found evidence in meteorites that hint at the discovery of a previously unknown region within the swirling disk of dust and gas known as the protoplanetary disk - which gave rise to the planets in our solar system.
Led by Kelly Miller, a doctoral student in the lab of Dante Lauretta, the principal investigator of NASA's OSIRIS-REx mission, the team has found evidence of minerals within meteorites that formed in an environment that was enhanced in oxygen and sulfur and date from a time before the particles stuck ...
New research finds oceanic microbes behave in a synchrony across ocean basins
2015-03-16
Researchers from the University of Hawai'i - M?noa (UHM) and colleagues found that microbial communities in different regions of the Pacific Ocean displayed strikingly similar daily rhythms in their metabolism despite inhabiting extremely different habitats - the nutrient-rich waters off California and the nutrient-poor waters north of Hawai'i. Furthermore, in each location, the dominant photoautotrophs - light-loving bacteria that need solar energy to help them photosynthesize food from inorganic substances - appear to initiate a cascade effect wherein the other major ...
American College of Cardiology's 64th Annual Scientific Session PM tip sheet for March 15, 2015
2015-03-16
The studies below will be presented at the American College of Cardiology's 64th Annual Scientific Session on Sunday, March 15.
1. Survey Suggests Cardiologists May Not Be Prepared to Counsel Patients on Heart Healthy Diets
Even though most doctors believe diet is important in preventing and managing cardiovascular disease, there are major gaps in their knowledge and, in turn, efforts to educate patients about heart healthy diets may be falling short, according to a recent survey of 236 cardiologists and internal medicine physicians and trainees at a large tertiary ...
Bendavia does not reduce scarring from angioplasty after heart attack
2015-03-16
Patients who received the new drug Bendavia before undergoing angioplasty or receiving a stent to clear blocked arteries after a heart attack showed no significant reduction in scarring as compared to patients given a placebo, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.
The study is the first randomized, controlled trial of Bendavia, a drug designed to reduce the extent of tissue damage in the heart through a new approach that targets mitochondria in the cells. Although patients receiving the drug showed a 10 ...
Novel anti-clotting therapy in halted trial no better than existing agents
2015-03-16
SAN DIEGO (March 15, 2015) -- A novel therapy that would allow doctors to turn the body's blood-clotting ability off and on in a more controlled way was about as effective as established anticoagulants in patients undergoing angioplasty but was associated with higher rates of moderate to severe bleeding, according to an analysis of data from a terminated Phase III trial presented at the American College of Cardiology's 64th Annual Scientific Session. The study was officially halted in August due to an excess of severe allergic reactions, so authors caution that the data ...
CT scans appear to dramatically improve diagnosis of heart disease
2015-03-16
SAN DIEGO (March 15, 2015) -- Use of computed tomography coronary angiography, which provides 3-D images of the heart, coupled with standard care allows doctors to more accurately diagnose coronary artery disease in patients presenting with chest pain, therefore, leading to more appropriate follow-up testing and treatments, according to research presented at the American College of Cardiology's 64th Annual Scientific Session. Data also showed a trend toward a lower incidence of heart attacks among the group receiving the tests, known as CT scans, compared to usual care. ...
After 1 year, patients on new drug fare better than standard therapy
2015-03-16
SAN DIEGO (March 15, 2015) -- Patients taking evolocumab--an investigational therapy previously shown to dramatically lower "bad" cholesterol--were half as likely to die, suffer a heart attack or stroke, be hospitalized or need a procedure to open blocked arteries compared with those who received standard care, according to research presented at the American College of Cardiology's 64th Annual Scientific Session in San Diego.
In this open-label study, the rate of cardiovascular events was 2.18 percent after one year in the standard of care group, most of whom were on ...
SAPIEN 3 improves 30-day outcomes for major endpoints
2015-03-16
SAN DIEGO (March 15, 2015) -- The SAPIEN 3 heart valve demonstrated lower death, stroke and paravalvular leak rates than earlier generation devices in patients at high risk for surgery and showed encouraging results in intermediate-risk patients, according to research presented at the American College of Cardiology's 64th Annual Scientific Session.
Transcatheter aortic valve replacement, known as TAVR, is approved for patients with severe aortic stenosis--narrowing of the valve in the heart's main artery--whose health profile makes them ineligible or high-risk candidates ...
Benefits seen for first-in-field brain shield used with TAVR
2015-03-16
SAN DIEGO (March 15, 2015) -- An investigational device that deflects debris away from the brain during transcatheter aortic valve replacement seems to improve in-hospital safety outcomes and cognitive scores at discharge, according to preliminary findings from a small randomized study presented at the American College of Cardiology's 64th Annual Scientific Session.
The valve replacement procedure, known as TAVR, dislodges minute particles from the clogged valve, freeing them to float through the bloodstream. Much of this debris travels "downstream" from the heart, but ...
SAPIEN valve, surgery equivalent at 5-years
2015-03-16
SAN DIEGO (March 15, 2015) -- Five-year data suggest that the SAPIEN transcatheter heart valve is a feasible option for patients with severe aortic stenosis deemed to be at high risk for open-heart surgery, though valve leakage was more common with the first-generation valve evaluated in this study than with surgery, according to research from PARTNER I presented at the American College of Cardiology's 64th Annual Scientific Session.
When the blockage of an aortic valve becomes severe, replacement is the only real treatment choice, but many elderly and frail people are ...
Self-expanding TAVR widens advantage over surgery at 2 years
2015-03-16
SAN DIEGO (March 15, 2015) -- Two-year data show a continued survival advantage for self-expanding transcatheter aortic valve replacement (TAVR) over standard surgery in high-risk patients with severe aortic stenosis, according to research presented at the American College of Cardiology's 64th Annual Scientific Session.
Aortic stenosis--a problem that occurs when the valve in the heart's main artery doesn't open fully--forces the heart to work harder to pump blood and is life-threatening over time. Valve replacement is common when this condition becomes severe, but the ...
MitraClip valve repair continues to show benefit in commercial setting
2015-03-16
SAN DIEGO (March 15, 2015) --The commercial track record with transcatheter mitral valve repair, approved for patients at high risk for surgery, compares favorably with pre-approval reports, according to findings from a U.S. registry presented at the American College of Cardiology's 64th Annual Scientific Session.
Healthy valves function as one-way gates that keep blood moving forward through the heart. Severely damaged mitral valves don't close properly, allowing blood to leak backward. If the valve isn't repaired or replaced, the condition can cause serious health ...
Police not prepared for death investigations
2015-03-16
Police are ill-equipped to investigate non-criminal deaths and face a challenge to avoid re-traumatising bereaved families as well as emotionally protecting themselves, according to QUT research.
Investigating death: the emotional and cultural challenges for police found it was usually junior officers sent to sudden death investigations and tasked with not only gathering evidence, but also comforting family members and explaining the coronial process.
The research has been published in the journal of Policing and Society.
"The vast majority of deaths are neither ...
Risk patterns identified that make people more vulnerable to PTSD
2015-03-16
NEW YORK, NY - Researchers have built a new computational tool that identifies 800 different ways people are at increased risk for post-traumatic stress disorder (PTSD), permitting for the first time a personalized prediction guide.
Results from the study out of NYU Langone Medical Center are published online (date) in the journal BMC Psychiatry.
"Our study shows that high-risk individuals who have experienced a traumatic event can be identified less than two weeks after they are first seen in the emergency department," says Arieh Y. Shalev, MD, the Barbara Wilson ...
Survey finds doctors want to learn more about diet and cardiovascular disease prevention
2015-03-16
NEW YORK, March 15, 2015 - Most physicians are aware of the importance of lifestyle factors in preventing cardiovascular disease (CVD) -- and believe diet is as important as statin therapy and exercise, according to a new survey from NYU Langone Medical Center.
Researchers found that a majority of doctors would welcome additional training in diet and nutrition so that they can effectively inform patients on the subject. The study will be presented at the American College of Cardiology's 64th Annual Scientific Session as a poster presentation.
The 28-question online survey, ...
Pollution levels linked to stroke-related narrowing of arteries
2015-03-16
NEW YORK, March 4, 2015 - Air pollution has been linked to a dangerous narrowing of neck arteries that occurs prior to strokes, according to researchers at NYU Langone Medical Center.
The scientists analyzed medical test records for more than 300,000 people living in New York, New Jersey or Connecticut. They found that people living in zip codes with the highest average levels of fine-particulate-matter pollution were significantly more likely to show signs of narrowing (stenosis) in their internal carotid arteries, compared to those living in zip codes with the lowest ...
Dialing a bespoke signal
2015-03-16
March 16, 2015, New York, NY - Exploring the fundamental mechanism by which a cell-surface receptor transmits its signal, an international team of Ludwig researchers and their colleagues has established proof of concept for an entirely new approach to drug design. They report that a class of synthetic molecules known as diabodies can, from outside the cell, latch onto a target receptor and manipulate it in such a manner as to induce distinct and varying effects within cells and tissues. Led by Christopher Garcia of Ludwig Stanford, the researchers show in lab experiments ...
Development of a carnivorous pitcher leaf
2015-03-16
Carnivorous plants have strange-shaped leaves, and they can grow on nutrient-poor environments by trapping and eating small animals. Charles Darwin, often called "the father of evolution", was also interested in carnivorous plants, and he wrote a book titled "Insectivorous Plants" published in 1875. Since then a lot of researches have been done, but how such strange-shaped leaves were altered during evolution remained unknown.
A research team in Japan has revealed how carnivorous pitcher leaves are formed in Sarracenia purpurea, a carnivorous plant native to North America. ...
Biodiversity-protected areas in Indonesia ineffective in preventing deforestation: NUS-led study
2015-03-16
Establishing protected areas in forests is one way to keep deforestation at bay and safeguard biodiversity. However, a study led by researchers from the National University of Singapore (NUS) has revealed that such a measure is ineffective in the case of biodiversity-focused protected areas in Indonesia.
The research, led by Assistant Professor Roman Carrasco of the Department of Biological Sciences at the NUS Faculty of Science and Assistant Professor Alex Cook of NUS' Saw Swee Hock School of Public Health, found that the monitoring and prevention of road construction ...
High-dose zinc acetate lozenges may help shorten symptoms associated with the common cold
2015-03-16
According to a meta-analysis published in BMC Family Practice, high dose zinc acetate lozenges may help shorten diverse symptoms associated with the common cold.
The common cold is an infection caused by over a hundred viruses, and it is a major cause of days off school or work and visits to a doctor.
A previous meta-analysis of three randomized trials found that high dose zinc acetate lozenges shorten the duration of colds by 42%. Since all of the three studies reported the duration of diverse respiratory symptoms and of systemic symptoms such as muscle ache and headache, ...
Neither more food nor better food -- still, fish biomass increases
2015-03-16
To increase the biomass of fish, contemporary ecological theory predicts that either the amount of food or the quality of the food has to increase. In a recent experiment, researchers at Umeå University doubled the fish biomass under identical food supply and food quality by only controlling how much of total food supply that was channelled to juvenile and adult fish, respectively. The results have major implications for the exploitation (harvest) of fish populations and the coexistence of predatory fish and their prey.
To increase the biomass of a population, contemporary ...
New possibilities for the treatment of breast cancer arise, with the help of mathematics
2015-03-16
A means of reprogramming a flawed immune response into an efficient anti-tumoral one was brought to light by the results of a translational trial relating to breast cancer. Thanks to the innovative combination of mathematical modelisation and experimentation, only 20 tests were necessary, whereas traditional experimentation would have required 596 tests to obtain the same results.
The study was jointly conducted by Doctor Marie-Agnès Doucey (Experimental oncology, Centre Ludwig de l'UNIL pour la recherche sur le cancer), Professor Ioannis Xenarios (UNIL, SIB, Vital-IT) ...
The devil's helmet for a legendary tiger moth
2015-03-16
The Menetries's tiger moth (Borearctia menetriesii) is the most rare and enigmatic representative among the Palearctic Arctiinae. During an expedition in almost inaccessible wild taiga area of Eastern Siberia, Russian scientists had the luck to encounter it. During their studies they also recorded feeding larva of this mysterious species on a native devil's helmet host plant for the first time. The study was published in the open access journal Nota Lepidopterologica.
The Menetries's tiger moth (Borearctia menetriesii) is the most rare and enigmatic representative among ...
The 10-point guide to the integral management of menopausal health
2015-03-16
Amsterdam, March 16, 2015 - Elsevier journal Maturitas, today announced the publication of a position statement by the European Menopause and Andropause Society (EMAS) covering the ten- point guide to the integral management of menopausal health. This has been written to mark the 10th EMAS Congress in Madrid May 20-22, 2015.
With increased longevity and more women becoming centenarians, management of the menopause and post-reproductive health is of growing importance as it has the potential to help promote health over several decades. Women have individual needs and the ...
American College of Cardiology's 64th Annual Scientific Session AM tip sheet
2015-03-16
The studies below will be presented at the American College of Cardiology's 64th Annual Scientific Session the morning of Saturday, March 14.
1. Depression May Influence Cardiovascular Outcomes
A new study adds to the evidence that depression may influence cardiovascular outcomes, prompting authors to call on cardiologists to pay closer attention to depression when managing patients with heart disease.
Researchers at Care Institute of Medical Sciences in India found depression to be independently associated with a greater chance of cardiovascular death and lower quality ...
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