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The Lancet: Experts call for a tobacco-free world by 2040

2015-03-13
Leading public health researchers today [Friday 13 March 2015] call for the sale of tobacco to be phased out by 2040, showing that with sufficient political support and stronger evidence-based action against the tobacco industry, a tobacco-free world - where less than 5% of adults use tobacco - could be possible in less than three decades. Writing in a major new Series in The Lancet, an international group of health and policy experts, led by Professors Robert Beaglehole and Ruth Bonita from the University of Auckland in New Zealand, call on the United Nations (UN) to ...

Antibiotic nanoparticles attack respiratory infection and reduce drug side effects

2015-03-13
Estoril, Portugal: Treating respiratory disease is often difficult because drugs have to cross biological barriers such as respiratory tissue and mucosa, and must therefore be given in large quantities in order for an effective amount to reach the target. Now researchers from Germany, Brazil and France have shown that the use of nanoparticles to carry antibiotics across biological barriers can be effective in treating lung infections. Doing so allows better delivery of the drug to the site of infection, and hence prevents the development of antibiotic resistance which ...

Chronic kidney disease may increase certain risks during pregnancy

2015-03-12
Highlights Among pregnant women, the risk for adverse pregnancy outcomes--such as preterm delivery or the need for neonatal intensive care--increased across stages of chronic kidney disease. The risks of intrauterine death or fetal malformations were not higher in women with chronic kidney disease. An estimated 26 million people in the United States have chronic kidney disease. Washington, DC (March 12, 2015) -- Even mild kidney disease during pregnancy may increase certain risks in the mother and baby, according to a study appearing in an upcoming issue of ...

New evidence that increasing economic inequality rises out of political partisanship

2015-03-12
BUFFALO, N.Y. - Political scientists at the University at Buffalo and Pennsylvania State University have published new research investigating how partisan differences in macroeconomic policy have contributed to substantial and rising economic inequality in the United States. The negative consequences of such policy decisions, researchers found, have a greater impact on people at the lower end of the economic spectrum, but are "significantly more muted" for those at the higher end of the spectrum. The study, "Partisan Differences in the Distributional Effects of Economic ...

Building a genomic GPS

2015-03-12
WORCESTER, MA - A new "app" for finding and mapping chromosomal loci using multicolored versions of CRISPR/Cas9, one of the hottest tools in biomedical research today, has been developed by scientists at the University of Massachusetts Medical School. This labeling system, details of which were published in PNAS and first presented at the American Society for Cell Biology/International Federation for Cell Biology annual meeting in Philadelphia in December, could be a key to understanding the spatial and temporal regulation of gene expression by allowing researchers to measure ...

E-cigarette advertising makes one crave ... tobacco?

2015-03-12
Television advertisements for e-cigarettes may be enticing current and even former tobacco smokers to reach for another cigarette. That is the finding by researchers Erin K. Maloney, Ph.D. and Joseph N. Cappella, Ph.D. from the University of Pennsylvania's Annenberg School for Communication, as reported in the journal Health Communication (online, March 2015). The researchers studied more than 800 daily, intermittent, and former smokers who watched e-cigarette advertising, and who then took a survey to determine smoking urges, intentions, and behaviors. Using a standard ...

NASA's Hubble observations suggest underground ocean on Jupiter's largest moon

NASA's Hubble observations suggest underground ocean on Jupiter's largest moon
2015-03-12
NASA's Hubble Space Telescope has the best evidence yet for an underground saltwater ocean on Ganymede, Jupiter's largest moon. The subterranean ocean is thought to have more water than all the water on Earth's surface. Identifying liquid water is crucial in the search for habitable worlds beyond Earth and for the search of life as we know it. "This discovery marks a significant milestone, highlighting what only Hubble can accomplish," said John Grunsfeld, associate administrator of NASA's Science Mission Directorate at NASA Headquarters, Washington. "In its 25 years ...

Toddlers in trouble

2015-03-12
CHICAGO --- A father's depression during the first years of parenting - as well as a mother's - can put their toddler at risk of developing troubling behaviors such as hitting, lying, anxiety and sadness during a critical time of development, according to a new Northwestern Medicine study. This is one of the first studies to show that the impact of a father's depression from postpartum to toddlerhood is the same as a mother's. Previous studies have focused mostly on mothers with postpartum depression and found that their symptoms may impact their children's behavior during ...

Unique proteins found in heat-loving organisms attach to plant matter

2015-03-12
Unique proteins newly discovered in heat-loving bacteria are more than capable of attaching themselves to plant cellulose, possibly paving the way for more efficient methods of converting plant matter into biofuels. The unusual proteins, called tapirins (derived from the Maori verb 'to join'), bind tightly to cellulose, a key structural component of plant cell walls, enabling these bacteria to break down cellulose. The conversion of cellulose to liquid biofuels, such as ethanol, is paramount to the use of renewable feedstocks. In a paper published online in the Journal ...

New protocol can help emergency departments evaluate patients with acute chest pain

2015-03-12
WINSTON-SALEM, N.C. - March 12, 2015 - A recently developed risk-evaluation protocol can help hospital emergency department personnel more efficiently determine which patients with acute chest pain can be sent home safely, according to a randomized trial conducted at Wake Forest Baptist Medical Center. The study, published in the current online issue of the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes, found that chest-pain patients who were evaluated with the new protocol, called the HEART Pathway, had 12 percent fewer cardiac tests, ...

Satellite sees rare subtropical storm 90Q in southern Atlantic

Satellite sees rare subtropical storm 90Q in southern Atlantic
2015-03-12
The Brazilian Navy Hydrographic Centre reported that a sub-tropical storm had formed on March 11 near east of the Brazilian state of Rio Grande do Sul, the southeastern most state in Brazil. NOAA's GOES-East satellite provided imagery of the Atlantic that showed Subtropical Cyclone 90Q off the southeastern coast of Brazil at 17:45 UTC (1:45 p.m. EDT). The system appeared to have fragmented banding of thunderstorms around the low-level center. The image was created by NASA/NOAA's GOES Project at NASA's Goddard Space Flight Center in Greenbelt, Maryland. At 1200 UTC (8 ...

Naturally acidic waters of Puget Sound surround UW's Friday Harbor Labs

Naturally acidic waters of Puget Sound surround UW's Friday Harbor Labs
2015-03-12
For more than 100 years, marine biologists at Friday Harbor Laboratories have studied the ecology of everything from tiny marine plants to giant sea stars. Now, as the oceans are undergoing a historic shift in chemistry, the lab is establishing itself as a place to study what that will mean for marine life. And the University of Washington laboratory is uniquely placed in naturally acidic waters that may be some of the first pushed over the edge by human-generated carbon emissions. A paper published last month in Limnology and Oceanography tracks about two years of ...

Case Western Reserve scientists find hidden meaning and 'speed limits' within genetic code

2015-03-12
Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code -- the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness -- and, ultimately, keep them from emerging in the first place. "Our discovery is that the genetic code is more complex than we knew," said senior researcher Jeff Coller, PhD, ...

Molecule-making machine simplifies complex chemistry

Molecule-making machine simplifies complex chemistry
2015-03-12
CHAMPAIGN, Ill. -- A new molecule-making machine could do for chemistry what 3-D printing did for engineering: Make it fast, flexible and accessible to anyone. Chemists at the University of Illinois, led by chemistry professor and medical doctor Martin D. Burke, built the machine to assemble complex small molecules at the click of a mouse, like a 3-D printer at the molecular level. The automated process has the potential to greatly speed up and enable new drug development and other technologies that rely on small molecules. "We wanted to take a very complex process, ...

Inflammatory factor IL-3 may play essential role in development of sepsis

2015-03-12
A new study finds that Interleukin-3 (IL-3), an inflammatory factor most associated with allergic reactions, appears to have an important role in the overwhelming, life-threatening immune reaction called sepsis. In the March 13 issue of Science, investigators from Massachusetts General Hospital (MGH) describe finding that the presence of IL-3 is essential to the development of sepsis in a mouse model of the condition and that IL-3 levels in human patients with sepsis are higher in those at greater risk of dying. "Sepsis is an extremely dangerous conditions that claims ...

Humans adapted to living in rainforests much sooner than thought

Humans adapted to living in rainforests much sooner than thought
2015-03-12
An international research team has shed new light on the diet of some of the earliest recorded humans in Sri Lanka. The researchers from Oxford University, working with a team from Sri Lanka and the University of Bradford, analysed the carbon and oxygen isotopes in the teeth of 26 individuals, with the oldest dating back 20,000 years. They found that nearly all the teeth analysed suggested a diet largely sourced from the rainforest. This study, published in the early online edition of the journal, Science, shows that early modern humans adapted to living in the rainforest ...

Measles cases predicted to almost double in Ebola epidemic countries

2015-03-12
An international study involving the University of Southampton suggests there could be a rise in measles cases of 100,000 across the three countries most affected by the Ebola outbreak in West Africa due to health system disruptions. The research in the journal Science, led by Princeton and Johns Hopkins University in the USA, predicts that the size of a measles outbreak will increase from 127,000 at the start of the Ebola epidemic in early 2014, to 227,000 after 18 months of the outbreak. This would result in an additional 5,000 measles deaths, and potentially as many ...

Political liberals display greater happiness, UCI study finds

2015-03-12
Irvine, Calif. - What does it mean to be happy? Is it how happy you say you are, or is it how happy you act? Previous research has found that political conservatives report being happier than political liberals. But UC Irvine psychologists have discovered that those on the left exhibit happier speech patterns and facial expressions. "The so-called 'happiness gap' between liberals and conservatives is more complicated than we thought," said Sean Wojcik, a doctoral student in psychology & social behavior at UCI and lead author of the study, which appears this month in Science. Prior ...

Summer storm weakening leads to more persistent heat extremes

2015-03-12
This is shown in a study to be published in the renowned journal Science by a team of researchers from the Potsdam Institute for Climate Impact Research. They link the findings to changes in the Arctic caused by man-made global warming. "When the great air streams in the sky above us get disturbed by climate change, this can have severe effects on the ground," says lead-author Dim Coumou. "While you might expect reduced storm activity to be something good, it turns out that this reduction leads to a greater persistence of weather systems in the Northern hemisphere mid-latitudes. ...

Magnetic brain stimulation

2015-03-12
CAMBRIDGE, Mass--Researchers at MIT have developed a method to stimulate brain tissue using external magnetic fields and injected magnetic nanoparticles -- a technique allowing direct stimulation of neurons, which could be an effective treatment for a variety of neurological diseases, without the need for implants or external connections. The research, conducted by Polina Anikeeva, an assistant professor of materials science and engineering, graduate student Ritchie Chen, and three others, has been published in the journal Science. Previous efforts to stimulate the ...

You are when you eat

2015-03-12
SAN DIEGO (Thursday, March 12, 2015) -- If you're looking to improve your heart health by changing your diet, when you eat may be just as important as what you eat. In a new study published today in Science, researchers at San Diego State University and the Salk Institute for Biological Studies found that by limiting the time span during which fruit flies could eat, they could prevent aging- and diet-related heart problems. The researchers also discovered that genes responsible for the body's circadian rhythm are integral to this process, but they're not yet sure how. Previous ...

3-D printer for small molecules opens access to customized chemistry

2015-03-12
Howard Hughes Medical Institute scientists have simplified the chemical synthesis of small molecules, eliminating a major bottleneck that limits the exploration of a class of compounds offering tremendous potential for medicine and technology. Scientists led by Martin Burke, an HHMI early career scientist at the University of Illinois at Urbana-Champaign, used a single automated process to synthesize 14 distinct classes of small molecules from a common set of building blocks. Burke's team envisions expanding the approach to enable the production of thousands of potentially ...

Distinct brain mechanisms related to dental pain relief

2015-03-12
Boston, Mass., USA - Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Michael L. Meier, Center for Dental Medicine, University of Zürich, Switzerland, will present a study titled "Distinct Brain Mechanisms Related to Dental Pain Relief." The IADR General Session is being held in conjunction with the 44th Annual Meeting of the American Association for Dental Research and the 39th Annual Meeting of the Canadian Association for Dental Research. Local anesthesia has made life more comfortable for dental ...

Study shows why exercise magnifies exhaustion for chronic fatigue syndrome patients

2015-03-12
The mechanism that causes high-performance athletes to "feel the burn" turns out to be the culprit in what makes people with chronic fatigue syndrome feel exhausted by the most common daily activities, new University of Florida Health research shows. Published in the February issue of the journal Pain, the study shows that the neural pathways that transmit feelings of fatigue to the brain might be to blame. In those with chronic fatigue syndrome, the pathways do their job too well. The findings also provide evidence for the first time that peripheral tissues such as ...

In vitro effects of topical neuromodulatory medication on orofacial tissue

2015-03-12
Boston, Mass., USA - Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher M.J. Al-Musawi, Newcastle University, Newcastle upon Tyne, UK, will present a study titled "In Vitro Effects of Topical Neuromodulatory Medication on Orofacial Tissue." The IADR General Session is being held in conjunction with the 44th Annual Meeting of the American Association for Dental Research and the 39th Annual Meeting of the Canadian Association for Dental Research. Systemic neuromodulatory medication (NM) such as Amitriptyline, ...
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